CD123 Monoclonal Antibody (6H6), PE-Cyanine7, eBioscience | Invitrogen 25-1239-42 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD123 Monoclonal Antibody (6H6), PE-Cyanine7, eBioscience

catalog :

25-1239-42

quantity :

100 Tests

price :

US 413.00

clonality :

monoclonal

host :

mouse

conjugate :

PE/Cy7

clone name :

6H6

reactivity :

human

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 25

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human	Barbosa R, Silva S, Silva S, Melo A, Pereira Santos M, Barata J, et al. Reduced BAFF-R and increased TACI expression in common variable immunodeficiency. J Clin Immunol. 2014;34:573-83 pubmed publisher
	Liu Z, Wang P, Yuan S, Wang Y, Cao P, Wen F, et al. LncRNA BC200/miR-150-5p/MYB positive feedback loop promotes the malignant proliferation of myelodysplastic syndrome. Cell Death Dis. 2022;13:126 pubmed publisher
	Roy A, Wang G, Iskander D, O Byrne S, Elliott N, O Sullivan J, et al. Transitions in lineage specification and gene regulatory networks in hematopoietic stem/progenitor cells over human development. Cell Rep. 2021;36:109698 pubmed publisher
	Baumgaertner P, Sankar M, Herrera F, Benedetti F, Barras D, Thierry A, et al. Unsupervised Analysis of Flow Cytometry Data in a Clinical Setting Captures Cell Diversity and Allows Population Discovery. Front Immunol. 2021;12:633910 pubmed publisher
	González Menéndez P, Romano M, Yan H, Deshmukh R, Papoin J, Oburoglu L, et al. An IDH1-vitamin C crosstalk drives human erythroid development by inhibiting pro-oxidant mitochondrial metabolism. Cell Rep. 2021;34:108723 pubmed publisher
	Ben Othman R, Cai B, Liu A, Varankovich N, He D, Blimkie T, et al. Systems Biology Methods Applied to Blood and Tissue for a Comprehensive Analysis of Immune Response to Hepatitis B Vaccine in Adults. Front Immunol. 2020;11:580373 pubmed publisher
	Parakrama R, Fogel E, Chandy C, Augustine T, Coffey M, Tesfa L, et al. Immune characterization of metastatic colorectal cancer patients post reovirus administration. BMC Cancer. 2020;20:569 pubmed publisher
	Psaila B, Wang G, Rodriguez Meira A, Li R, Heuston E, Murphy L, et al. Single-Cell Analyses Reveal Megakaryocyte-Biased Hematopoiesis in Myelofibrosis and Identify Mutant Clone-Specific Targets. Mol Cell. 2020;78:477-492.e8 pubmed publisher
	Schulz V, Yan H, Lezon Geyda K, An X, Hale J, Hillyer C, et al. A Unique Epigenomic Landscape Defines Human Erythropoiesis. Cell Rep. 2019;28:2996-3009.e7 pubmed publisher
	Lagou V, Garcia Perez J, Smets I, Van Horebeek L, Vandebergh M, Chen L, et al. Genetic Architecture of Adaptive Immune System Identifies Key Immune Regulators. Cell Rep. 2018;25:798-810.e6 pubmed publisher
	Bastian O, Croes M, Alblas J, Koenderman L, Leenen L, Blokhuis T. Neutrophils Inhibit Synthesis of Mineralized Extracellular Matrix by Human Bone Marrow-Derived Stromal Cells In Vitro. Front Immunol. 2018;9:945 pubmed publisher
	Kinstrie R, Karamitros D, Goardon N, Morrison H, Hamblin M, Robinson L, et al. Heterogeneous leukemia stem cells in myeloid blast phase chronic myeloid leukemia. Blood Adv. 2016;1:160-169 pubmed publisher
	Chahroudi A, Cartwright E, Lee S, Mavigner M, Carnathan D, Lawson B, et al. Target cell availability, rather than breast milk factors, dictates mother-to-infant transmission of SIV in sooty mangabeys and rhesus macaques. PLoS Pathog. 2014;10:e1003958 pubmed publisher
	Ataide M, Andrade W, Zamboni D, Wang D, Souza M, Franklin B, et al. Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection. PLoS Pathog. 2014;10:e1003885 pubmed publisher
	Bosinger S, Johnson Z, Folkner K, Patel N, Hashempour T, Jochems S, et al. Intact type I Interferon production and IRF7 function in sooty mangabeys. PLoS Pathog. 2013;9:e1003597 pubmed publisher
	Compte N, Zouaoui Boudjeltia K, Vanhaeverbeek M, De Breucker S, Tassignon J, Trelcat A, et al. Frailty in old age is associated with decreased interleukin-12/23 production in response to toll-like receptor ligation. PLoS ONE. 2013;8:e65325 pubmed publisher
	Frleta D, Ochoa C, Kramer H, Khan S, Stacey A, Borrow P, et al. HIV-1 infection-induced apoptotic microparticles inhibit human DCs via CD44. J Clin Invest. 2012;122:4685-97 pubmed publisher
	Metenou S, Kovacs M, Dembele B, Coulibaly Y, Klion A, Nutman T. Interferon regulatory factor modulation underlies the bystander suppression of malaria antigen-driven IL-12 and IFN-Î³ in filaria-malaria co-infection. Eur J Immunol. 2012;42:641-50 pubmed publisher
	De Gobbi M, Garrick D, Lynch M, Vernimmen D, Hughes J, Goardon N, et al. Generation of bivalent chromatin domains during cell fate decisions. Epigenetics Chromatin. 2011;4:9 pubmed publisher
	Meera S, Madhuri T, Manisha G, Ramesh P. Irreversible loss of pDCs by apoptosis during early HIV infection may be a critical determinant of immune dysfunction. Viral Immunol. 2010;23:241-9 pubmed publisher
	Cavaleiro R, Baptista A, Soares R, Tendeiro R, Foxall R, Gomes P, et al. Major depletion of plasmacytoid dendritic cells in HIV-2 infection, an attenuated form of HIV disease. PLoS Pathog. 2009;5:e1000667 pubmed publisher
	Xu W, He B, Chiu A, Chadburn A, Shan M, Buldys M, et al. Epithelial cells trigger frontline immunoglobulin class switching through a pathway regulated by the inhibitor SLPI. Nat Immunol. 2007;8:294-303 pubmed
	Peduzzi E, Groeper C, Schütte D, Zajac P, Rondini S, Mensah Quainoo E, et al. Local activation of the innate immune system in Buruli ulcer lesions. J Invest Dermatol. 2007;127:638-45 pubmed
	Assaf C, Gellrich S, Whittaker S, Robson A, Cerroni L, Massone C, et al. CD56-positive haematological neoplasms of the skin: a multicentre study of the Cutaneous Lymphoma Project Group of the European Organisation for Research and Treatment of Cancer. J Clin Pathol. 2007;60:981-9 pubmed
	Jaye D, Geigerman C, Herling M, Eastburn K, Waller E, Jones D. Expression of the plasmacytoid dendritic cell marker BDCA-2 supports a spectrum of maturation among CD4+ CD56+ hematodermic neoplasms. Mod Pathol. 2006;19:1555-62 pubmed

product information

Product Type :

Antibody

Product Name :

CD123 Monoclonal Antibody (6H6), PE-Cyanine7, eBioscience

Catalog # :

25-1239-42

Quantity :

100 Tests

Price :

US 413.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (1 ug)/test

Species :

Human

Clone :

6H6

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

IL-3Ra (Interleukin-3 receptor subunit alpha) belongs to the type I cytokine receptor family and is a heterodimer with a unique alpha chain paired with the common beta (beta c or CDw131) subunit. IL-3Ra is responsible for the transmission of signal of Interleukin-3. IL-3Ra and IL-3Rb chain heterodimerization is induced by Interleukin-3, which is required for receptor activation but not high affinity binding. IL-3Ra is also reported that IL-3Ra subunits are overexpressed on acute myeloid leukemia (AML) blasts compared with normal hematopoietic cells and are thus potential targets for novel therapeutic agents.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (1 ug)/test

Aliases :

CD123; CD123 antigen; CDw123; Cyrl; cytokine receptor-like protein CYRL; hIL-3Ra; Il-3 alpha subunit; IL-3 receptor alpha chain; IL-3 receptor alpha SP2 isoform; IL-3 receptor subunit alpha; IL3R; IL-3R subunit alpha; Il3ra; IL-3RA; IL-3R-alpha; IL3RAY; IL3RX; IL3RY; interleukin 3 receptor subunit alpha; interleukin 3 receptor, alpha; interleukin 3 receptor, alpha (low affinity); interleukin 3 receptor, alpha chain; interleukin-3 receptor class II alpha chain; Interleukin-3 receptor subunit alpha; Sut-1

more info or order :

Invitrogen product webpage