CD122 Monoclonal Antibody (TM-b1 (TM-beta1)), PE-Cyanine7, eBioscience | Invitrogen 25-1222-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD122 Monoclonal Antibody (TM-b1 (TM-beta1)), PE-Cyanine7, eBioscience

catalog :

25-1222-82

quantity :

100 ug

price :

US 484.00

clonality :

monoclonal

host :

rat

conjugate :

PE/Cy7

clone name :

TM-b1 (TM-beta1)

reactivity :

mouse

application :

flow cytometry

citations: 5

Reference
LUCAS B, White A, Cosway E, Parnell S, James K, Jones N, et al. Diversity in medullary thymic epithelial cells controls the activity and availability of iNKT cells. Nat Commun. 2020;11:2198 pubmed publisher
Dege C, Fegan K, Creamer J, Berrien Elliott M, Luff S, Kim D, et al. Potently Cytotoxic Natural Killer Cells Initially Emerge from Erythro-Myeloid Progenitors during Mammalian Development. Dev Cell. 2020;53:229-239.e7 pubmed publisher
Wang S, Xia P, Chen Y, Qu Y, Xiong Z, Ye B, et al. Regulatory Innate Lymphoid Cells Control Innate Intestinal Inflammation. Cell. 2017;171:201-216.e18 pubmed publisher
Kim P, Kwilas A, Xu W, Alter S, Jeng E, Wong H, et al. IL-15 superagonist/IL-15RÎ±Sushi-Fc fusion complex (IL-15SA/IL-15RÎ±Su-Fc; ALT-803) markedly enhances specific subpopulations of NK and memory CD8+ T cells, and mediates potent anti-tumor activity against murine breast and colon carcinomas. Oncotarget. 2016;7:16130-45 pubmed publisher
French J, Roark C, Born W, O Brien R. {gamma}{delta} T cell homeostasis is established in competition with {alpha}{beta} T cells and NK cells. Proc Natl Acad Sci U S A. 2005;102:14741-6 pubmed

product information

Product Type :

Antibody

Product Name :

CD122 Monoclonal Antibody (TM-b1 (TM-beta1)), PE-Cyanine7, eBioscience

Catalog # :

25-1222-82

Quantity :

100 ug

Price :

US 484.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.25 ug/test

Species :

Mouse

Clone :

TM-b1 (TM-beta1)

Isotype :

IgG2b, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

CD122 (Interleukin 2 receptor) is involved in T cell-mediated immune responses, primarily expressed in the hematopoietic system and is present in 3 forms. The low affinity form of CD122 is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from CD122. The protein encoded by the CD122 gene represents the beta subunit and is a type I membrane protein. Diseases associate with CD122 protein dysfunction include oligoarticular juvenile idiopathic arthritis and rheumatoid factor negative juvenile idiopathic arthritis.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 ug/test

Aliases :

CD122; CD122 antigen; high affinity IL-2 receptor beta subunit; high affinity IL-2 receptor subunit beta; IL-15 receptor beta chain; IL15RB; IL15Rbeta; IL-15Rbeta; IL-2 receptor beta chain; IL-2 receptor subunit beta; IL-2/15 receptor-beta; Il-2/15Rbeta; IL-2R subunit beta; IL2RB; IL-2RB; IL2RBC; Il-2Rbeta; interleukin 15 receptor, beta; interleukin 2 receptor subunit beta; interleukin 2 receptor, beta; interleukin 2 receptor, beta chain; Interleukin-15 receptor subunit beta; Interleukin-2 receptor subunit beta; p70; p70-75; p75