CD105 (Endoglin) Monoclonal Antibody (MJ7/18), PE-Cyanine7, eBioscience | Invitrogen 25-1051-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD105 (Endoglin) Monoclonal Antibody (MJ7/18), PE-Cyanine7, eBioscience

catalog :

25-1051-82

quantity :

100 µg

price :

US 419.00

clonality :

monoclonal

host :

rat

conjugate :

PE/Cy7

clone name :

MJ7/18

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 23

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse	Weishaupt H, Attema J. A Method to Study the Epigenetic Chromatin States of Rare Hematopoietic Stem and Progenitor Cells; MiniChIP-Chip. Biol Proced Online. 2010;12:1-17 pubmed publisher
	Kyryk V, Tsupykov O, Ustymenko A, Smozhanik E, Govbakh I, Butenko G, et al. Age-related ultrastructural changes in spheroids of the adipose-derived multipotent mesenchymal stromal cells from ovariectomized mice. Front Cell Neurosci. 2023;17:1072750 pubmed publisher
	L xf3 pez D, Apostol A, Lebish E, Valencia C, Romero Mulero M, Pavlovich P, et al. Prenatal inflammation perturbs murine fetal hematopoietic development and causes persistent changes to postnatal immunity. Cell Rep. 2022;41:111677 pubmed publisher
	Yuan O, Ugale A, De Marchi T, Anthonydhason V, Konturek Ciesla A, Wan H, et al. A somatic mutation in moesin drives progression into acute myeloid leukemia. Sci Adv. 2022;8:eabm9987 pubmed publisher
	Seras Franzoso J, D xed az Riascos Z, Corchero J, Gonz xe1 lez P, Garc xed a Aranda N, Manda xf1 a M, et al. Extracellular vesicles from recombinant cell factories improve the activity and efficacy of enzymes defective in lysosomal storage disorders. J Extracell Vesicles. 2021;10:e12058 pubmed publisher
	Wei H, Zhou W, Hu G, Shi C. Induction of mesenchymal stem cell‑like transformation in rat primary glial cells using hypoxia, mild hypothermia and growth factors. Mol Med Rep. 2021;23: pubmed publisher
	Zhang C, Gu X, Zhao G, Wang W, Shao J, Zhu J, et al. Extracellular HMGB-1 activates inflammatory signaling in tendon cells and tissues. Ther Adv Chronic Dis. 2020;11:2040622320956429 pubmed publisher
	Huang J, Zhao L, Fan Y, Liao L, Ma P, Xiao G, et al. The microRNAs miR-204 and miR-211 maintain joint homeostasis and protect against osteoarthritis progression. Nat Commun. 2019;10:2876 pubmed publisher
	Yu B, Li Q, Zhou M. LPS‑induced upregulation of the TLR4 signaling pathway inhibits osteogenic differentiation of human periodontal ligament stem cells under inflammatory conditions. Int J Mol Med. 2019;43:2341-2351 pubmed publisher
	Stivala S, Codilupi T, Brkic S, Baerenwaldt A, Ghosh N, Hao Shen H, et al. Targeting compensatory MEK/ERK activation increases JAK inhibitor efficacy in myeloproliferative neoplasms. J Clin Invest. 2019;130:1596-1611 pubmed publisher
	Gulati G, Murphy M, Marecic O, Lopez M, Brewer R, Koepke L, et al. Isolation and functional assessment of mouse skeletal stem cell lineage. Nat Protoc. 2018;13:1294-1309 pubmed publisher
	Ge J, Burnier L, Adamopoulou M, Kwa M, Schaks M, Rottner K, et al. RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells. J Biol Chem. 2018;293:9358-9369 pubmed publisher
	Redgrave R, Tual Chalot S, Davison B, Singh E, Hall D, Amirrasouli M, et al. Cardiosphere-Derived Cells Require Endoglin for Paracrine-Mediated Angiogenesis. Stem Cell Reports. 2017;8:1287-1298 pubmed publisher
	Ojeda Fernandez L, Recio Poveda L, Aristorena M, Lastres P, Blanco F, Sanz Rodriguez F, et al. Mice Lacking Endoglin in Macrophages Show an Impaired Immune Response. PLoS Genet. 2016;12:e1005935 pubmed publisher
	Shankman L, Gomez D, Cherepanova O, Salmon M, Alencar G, Haskins R, et al. KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis. Nat Med. 2015;21:628-37 pubmed publisher
	Cheng C, Lee Y, Lin S, HuangFu W, Liu I. Cell-autonomous heparanase modulates self-renewal and migration in bone marrow-derived mesenchymal stem cells. J Biomed Sci. 2014;21:21 pubmed publisher
	Cheng C, Lian W, Hsiao F, Liu I, Lin S, Lee Y, et al. Isolation and characterization of novel murine epiphysis derived mesenchymal stem cells. PLoS ONE. 2012;7:e36085 pubmed publisher
	Yan A, Avraham T, Zampell J, Haviv Y, Weitman E, Mehrara B. Adipose-derived stem cells promote lymphangiogenesis in response to VEGF-C stimulation or TGF-?1 inhibition. Future Oncol. 2011;7:1457-73 pubmed publisher
	Wu X, Yu G, Parks H, Hebert T, Goh B, Dietrich M, et al. Circadian mechanisms in murine and human bone marrow mesenchymal stem cells following dexamethasone exposure. Bone. 2008;42:861-70 pubmed publisher
	Perez Gomez E, Villa Morales M, Santos J, Fernandez Piqueras J, Gamallo C, Dotor J, et al. A role for endoglin as a suppressor of malignancy during mouse skin carcinogenesis. Cancer Res. 2007;67:10268-77 pubmed
	Korpanty G, Carbon J, Grayburn P, Fleming J, Brekken R. Monitoring response to anticancer therapy by targeting microbubbles to tumor vasculature. Clin Cancer Res. 2007;13:323-30 pubmed
	Onoe T, Ohdan H, Tokita D, Shishida M, Tanaka Y, Hara H, et al. Liver sinusoidal endothelial cells tolerize T cells across MHC barriers in mice. J Immunol. 2005;175:139-46 pubmed
	Quintanilla M, Ramirez J, Perez Gomez E, Romero D, Velasco B, Letarte M, et al. Expression of the TGF-beta coreceptor endoglin in epidermal keratinocytes and its dual role in multistage mouse skin carcinogenesis. Oncogene. 2003;22:5976-85 pubmed

product information

Product Type :

Antibody

Product Name :

CD105 (Endoglin) Monoclonal Antibody (MJ7/18), PE-Cyanine7, eBioscience

Catalog # :

25-1051-82

Quantity :

100 µg

Price :

US 419.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.25 µg/test

Species :

Mouse

Clone :

MJ7/18

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 µg/test

Aliases :

AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); Eng; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein

more info or order :

Invitrogen product webpage