CD73 Monoclonal Antibody (eBioTY/11.8 (TY/11.8)), PE-Cyanine7, eBioscience™ | Invitrogen 25-0731-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD73 Monoclonal Antibody (eBioTY/11.8 (TY/11.8)), PE-Cyanine7, eBioscience™

catalog :

25-0731-82

quantity :

100 µg

price :

US 309.00

clonality :

monoclonal

host :

rat

conjugate :

PE/Cy7

clone name :

eBioTY/11.8 (TY/11.8)

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; 1:50; fig 3h	Bemark M, Hazanov H, Strömberg A, Komban R, Holmqvist J, Köster S, et al. Limited clonal relatedness between gut IgA plasma cells and memory B cells after oral immunization. Nat Commun. 2016;7:12698 pubmed publisher
	Davies O, Grover L, Lewis M, Liu Y. PDGF is a potent initiator of bone formation in a tissue engineered model of pathological ossification. J Tissue Eng Regen Med. 2018;12:e355-e367 pubmed publisher
	Guichard V, Bonilla N, Durand A, Audemard Verger A, Guilbert T, Martin B, et al. Calcium-mediated shaping of naive CD4 T-cell phenotype and function. elife. 2017;6: pubmed publisher
	Buus T, Ødum N, Geisler C, Lauritsen J. Three distinct developmental pathways for adaptive and two IFN-γ-producing γδ T subsets in adult thymus. Nat Commun. 2017;8:1911 pubmed publisher
	Chamieh F, Collignon A, Coyac B, Lesieur J, Ribes S, Sadoine J, et al. Accelerated craniofacial bone regeneration through dense collagen gel scaffolds seeded with dental pulp stem cells. Sci Rep. 2016;6:38814 pubmed publisher
	Jhala G, Chee J, Trivedi P, Selck C, Gurzov E, Graham K, et al. Perinatal tolerance to proinsulin is sufficient to prevent autoimmune diabetes. JCI Insight. 2016;1:e86065 pubmed publisher
	Young A, Ngiow S, Barkauskas D, Sult E, Hay C, Blake S, et al. Co-inhibition of CD73 and A2AR Adenosine Signaling Improves Anti-tumor Immune Responses. Cancer Cell. 2016;30:391-403 pubmed publisher
	Toomer K, Yuan X, Yang J, Dee M, Yu A, Malek T. Developmental Progression and Interrelationship of Central and Effector Regulatory T Cell Subsets. J Immunol. 2016;196:3665-76 pubmed publisher
	TejÃ³n G, ManrÃquez V, De Calisto J, Flores SantibÃ¡Ã±ez F, Hidalgo Y, CrisÃ³stomo N, et al. Vitamin A Impairs the Reprogramming of Tregs into IL-17-Producing Cells during Intestinal Inflammation. Biomed Res Int. 2015;2015:137893 pubmed publisher
	Garimella M, Kour S, Piprode V, Mittal M, Kumar A, Rani L, et al. Adipose-Derived Mesenchymal Stem Cells Prevent Systemic Bone Loss in Collagen-Induced Arthritis. J Immunol. 2015;195:5136-48 pubmed publisher
	Cheng C, Lee Y, Lin S, HuangFu W, Liu I. Cell-autonomous heparanase modulates self-renewal and migration in bone marrow-derived mesenchymal stem cells. J Biomed Sci. 2014;21:21 pubmed publisher
	Du Y, Roh D, Mann M, Funderburgh M, Funderburgh J, Schuman J. Multipotent stem cells from trabecular meshwork become phagocytic TM cells. Invest Ophthalmol Vis Sci. 2012;53:1566-75 pubmed publisher
	Yan A, Avraham T, Zampell J, Haviv Y, Weitman E, Mehrara B. Adipose-derived stem cells promote lymphangiogenesis in response to VEGF-C stimulation or TGF-?1 inhibition. Future Oncol. 2011;7:1457-73 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD73 Monoclonal Antibody (eBioTY/11.8 (TY/11.8)), PE-Cyanine7, eBioscience™

Catalog # :

25-0731-82

Quantity :

100 µg

Price :

US 309.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.125 µg/test

Species :

Mouse

Clone :

eBioTY/11.8 (TY/11.8)

Isotype :

IgG1

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

CD73 (Ecto-5-prime-nucleotidase, 5-prime-ribonucleotide phosphohydrolase) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. CD73 consists of a dimer of 2 identical 70 kDa subunits bound externally to the plasma membrane by a glycosyl phosphatidyl inositol linkage. CD73 is used as a marker of lymphocyte differentiation. Consequently, a deficiency of CD73 occurs in a variety of immunodeficiency diseases. Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from CD73 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate. The CD73 gene has been localized to 6q14-q21 by immunofluorescence and a study of a panel of human x mouse hybrids that contained fragments of chromosome 6 as translocations. Defects in the CD73 gene can lead to the calcification of joints and arteries, and intestinal tuberculosis. Two transcript variants encoding different isoforms of CD73 have been found.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.125 µg/test

Aliases :

2210401F01Rik; 5 nucleotidase, ecto; 5' nucleotidase, ecto; 5'-NT; 5'-nucleotidase; 5'-nucleotidase ecto; 5'-nucleotidase, ecto (CD73); AI447961; CALJA; CD73; E5NT; ecto-5'-nucleotidase; eN; eNT; NT; Nt5; Nt5e; NTE; Purine 5-Prime-Nucleotidase

more info or order :

Invitrogen product webpage