CD68 Monoclonal Antibody (FA-11), PE-Cyanine7, eBioscience | Invitrogen 25-0681-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD68 Monoclonal Antibody (FA-11), PE-Cyanine7, eBioscience

catalog :

25-0681-82

quantity :

100 µg

price :

US 409

clonality :

monoclonal

host :

rat

conjugate :

PE/Cy7

clone name :

FA-11

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; 1:130; loading ...	Glausen T, Carrillo G, Jin R, Boyle J, Saeij J, Wohlfert E, et al. The Toxoplasma Polymorphic Effector GRA15 Mediates Seizure Induction by Modulating Interleukin-1 Signaling in the Brain. MBio. 2021;12:e0133121 pubmed publisher
flow cytometry; mouse; 1:200; loading ...; fig 4s1	Madel M, Ibáñez L, Ciucci T, Halper J, Rouleau M, Boutin A, et al. Dissecting the phenotypic and functional heterogeneity of mouse inflammatory osteoclasts by the expression of Cx3cr1. elife. 2020;9: pubmed publisher
	Mucci A, Lopez Rodriguez E, Hetzel M, Liu S, Suzuki T, Happle C, et al. iPSC-Derived Macrophages Effectively Treat Pulmonary Alveolar Proteinosis in Csf2rb-Deficient Mice. Stem Cell Reports. 2018;11:696-710 pubmed publisher
	Chi B, Wang S, Bi S, Qin W, Wu D, Luo Z, et al. Effects of ganoderic acid A on lipopolysaccharide-induced proinflammatory cytokine release from primary mouse microglia cultures. Exp Ther Med. 2018;15:847-853 pubmed publisher
	Steggerda S, Bennett M, Chen J, Emberley E, Huang T, Janes J, et al. Inhibition of arginase by CB-1158 blocks myeloid cell-mediated immune suppression in the tumor microenvironment. J Immunother Cancer. 2017;5:101 pubmed publisher
	Jin R, Blair S, Warunek J, Heffner R, Blader I, Wohlfert E. Regulatory T Cells Promote Myositis and Muscle Damage in Toxoplasma gondii Infection. J Immunol. 2017;198:352-362 pubmed
	Mucci A, Kunkiel J, Suzuki T, Brennig S, Glage S, Kühnel M, et al. Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency. Stem Cell Reports. 2016;7:292-305 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD68 Monoclonal Antibody (FA-11), PE-Cyanine7, eBioscience

Catalog # :

25-0681-82

Quantity :

100 µg

Price :

US 409

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 1 µg/test

Species :

Mouse

Clone :

FA-11

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 µg/test

Aliases :

CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen

more info or order :

Invitrogen product webpage