CD41a Monoclonal Antibody (HIP8), PE-Cyanine7, eBioscience™ | Invitrogen 25-0419-41 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD41a Monoclonal Antibody (HIP8), PE-Cyanine7, eBioscience™

catalog :

25-0419-41

quantity :

25Tests

price :

US 160

clonality :

monoclonal

host :

mouse

conjugate :

PE/Cy7

clone name :

HIP8

reactivity :

human

application :

flow cytometry

citations: 9

Reference
Zhao K, Zheng W, Dong X, Yin R, Gao R, Li X, et al. EDAG promotes the expansion and survival of human CD34+ cells. PLoS ONE. 2018;13:e0190794 pubmed publisher
Xie R, Hu P, Li W, Ren Y, Yang J, Yang Y, et al. The effect of platelet-derived microparticles in stored apheresis platelet concentrates on polymorphonuclear leucocyte respiratory burst. Vox Sang. 2014;106:234-41 pubmed publisher
Balduini A, Di Buduo C, Malara A, Lecchi A, Rebuzzini P, Currao M, et al. Constitutively released adenosine diphosphate regulates proplatelet formation by human megakaryocytes. Haematologica. 2012;97:1657-65 pubmed publisher
Ekser B, Lin C, Long C, Echeverri G, Hara H, Ezzelarab M, et al. Potential factors influencing the development of thrombocytopenia and consumptive coagulopathy after genetically modified pig liver xenotransplantation. Transpl Int. 2012;25:882-96 pubmed publisher
Dayananda K, Singh I, Mondal N, Neelamegham S. von Willebrand factor self-association on platelet GpIbalpha under hydrodynamic shear: effect on shear-induced platelet activation. Blood. 2010;116:3990-8 pubmed publisher
Blue R, Kowalska M, Hirsch J, Murcia M, Janczak C, Harrington A, et al. Structural and therapeutic insights from the species specificity and in vivo antithrombotic activity of a novel alphaIIb-specific alphaIIbbeta3 antagonist. Blood. 2009;114:195-201 pubmed publisher
Shah M, Bergeron A, Dong J, LÃ³pez J. Flow cytometric measurement of microparticles: pitfalls and protocol modifications. Platelets. 2008;19:365-72 pubmed publisher
Arimura Y, Vang T, Tautz L, Williams S, Mustelin T. TCR-induced downregulation of protein tyrosine phosphatase PEST augments secondary T cell responses. Mol Immunol. 2008;45:3074-84 pubmed publisher
Rajesh D, Chinnasamy N, Mitalipov S, Wolf D, Slukvin I, Thomson J, et al. Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells. Stem Cells. 2007;25:490-9 pubmed

product information

Product Type :

Antibody

Product Name :

CD41a Monoclonal Antibody (HIP8), PE-Cyanine7, eBioscience™

Catalog # :

25-0419-41

Quantity :

25Tests

Price :

US 160

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 µL (0.125 µg)/test

Species :

Human

Clone :

HIP8

Isotype :

IgG1, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

CD41 (platelet glycoprotein IIb, ITGA2B) is composed of two subunits -120 kDa a, alpha and 23 kDa b, beta- that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. CD41 is also involved in blood coagulation by mediating platelet aggregation. Upon blood vessel damage, CD41 binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during the early stages of hematopoietic differentiation. Diseases associated with CD41 dysfunction include Glansmann Thrombasthenia, and Platelet type-16 bleeding disorder.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 µL (0.125 µg)/test

Aliases :

BDPLT2, CD41, CD41B, GP2B, GPIIb, GT, GTA, HPA3, GPalpha IIb, integrin alpha-IIb, platelet fibrinogen receptor, alpha subunit, platelet membrane glycoprotein IIb, platelet-specific antigen BAK, ITGA2B