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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD39 Monoclonal Antibody (24DMS1), PE-Cyanine7, eBioscience
catalog :
25-0391-82
quantity :
100 ug
price :
US 449.00
clonality :
monoclonal
host :
rat
conjugate :
PE/Cy7
clone name :
24DMS1
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 29
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 8b
Lu L, Li T, Feng X, Liu Z, Liu Y, Chao T, et al. Excessive immunosuppression by regulatory T cells antagonizes T cell response to schistosome infection in PD-1-deficient mice. PLoS Pathog. 2022;18:e1010596 pubmed publisher
  • flow cytometry; mouse; loading ...
Levine A, Mendoza A, Hemmers S, Moltedo B, Niec R, Schizas M, et al. Stability and function of regulatory T cells expressing the transcription factor T-bet. Nature. 2017;546:421-425 pubmed publisher
  • flow cytometry; mouse; fig s3
Chen S, Chang B, Chang S, Tong T, Ham S, Sherry B, et al. BTK inhibition results in impaired CXCR4 chemokine receptor surface expression, signaling and function in chronic lymphocytic leukemia. Leukemia. 2016;30:833-43 pubmed publisher
Que W, Ueta H, Hu X, Morita Nakagawa M, Fujino M, Ueda D, et al. Temporal and spatial dynamics of immune cells in spontaneous liver transplant tolerance. iScience. 2023;26:107691 pubmed publisher
Martens P, Ellis D, Bruggeman Y, Viaene M, Laureys J, Teyton L, et al. Preventing type 1 diabetes in late-stage pre-diabetic NOD mice with insulin: A central role for alum as adjuvant. Front Endocrinol (Lausanne). 2022;13:1023264 pubmed publisher
Grebinoski S, Zhang Q, Cillo A, Manne S, Xiao H, Brunazzi E, et al. Autoreactive CD8+ T cells are restrained by an exhaustion-like program that is maintained by LAG3. Nat Immunol. 2022;23:868-877 pubmed publisher
Kragten N, Taggenbrock R, Parga Vidal L, van Lier R, Stark R, van Gisbergen K. Hobit and Blimp-1 instruct the differentiation of iNKT cells into resident-phenotype lymphocytes after lineage commitment. Eur J Immunol. 2022;52:389-403 pubmed publisher
Mendu S, Stremska M, Schappe M, Moser E, Krupa J, Rogers J, et al. Targeting the ion channel TRPM7 promotes the thymic development of regulatory T cells by promoting IL-2 signaling. Sci Signal. 2020;13: pubmed publisher
Calvo Barreiro L, Eixarch H, Ponce Alonso M, Castillo M, Lebrón Galán R, Mestre L, et al. A Commercial Probiotic Induces Tolerogenic and Reduces Pathogenic Responses in Experimental Autoimmune Encephalomyelitis. Cells. 2020;9: pubmed publisher
Zhao R, Qiao J, Zhang X, Zhao Y, Meng X, Sun D, et al. Toll-Like Receptor-Mediated Activation of CD39 Internalization in BMDCs Leads to Extracellular ATP Accumulation and Facilitates P2X7 Receptor Activation. Front Immunol. 2019;10:2524 pubmed publisher
Adamiak M, Bujko K, Brzeźniakiewicz Janus K, Kucia M, Ratajczak J, Ratajczak M. The Inhibition of CD39 and CD73 Cell Surface Ectonucleotidases by Small Molecular Inhibitors Enhances the Mobilization of Bone Marrow Residing Stem Cells by Decreasing the Extracellular Level of Adenosine. Stem Cell Rev Rep. 2019;15:892-899 pubmed publisher
Rothweiler S, Feldbrügge L, Jiang Z, Csizmadia E, Longhi M, Vaid K, et al. Selective deletion of ENTPD1/CD39 in macrophages exacerbates biliary fibrosis in a mouse model of sclerosing cholangitis. Purinergic Signal. 2019;15:375-385 pubmed publisher
Shin B, Kress R, Kramer P, Darley Usmar V, Bellis S, Harrington L. Effector CD4 T cells with progenitor potential mediate chronic intestinal inflammation. J Exp Med. 2018;215:1803-1812 pubmed publisher
Hirata Y, Furuhashi K, Ishii H, Li H, Pinho S, Ding L, et al. CD150high Bone Marrow Tregs Maintain Hematopoietic Stem Cell Quiescence and Immune Privilege via Adenosine. Cell Stem Cell. 2018;22:445-453.e5 pubmed publisher
Chatterjee S, Daenthanasanmak A, Chakraborty P, Wyatt M, Dhar P, Selvam S, et al. CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response. Cell Metab. 2018;27:85-100.e8 pubmed publisher
Pandya H, Shen M, Ichikawa D, Sedlock A, Choi Y, Johnson K, et al. Differentiation of human and murine induced pluripotent stem cells to microglia-like cells. Nat Neurosci. 2017;20:753-759 pubmed publisher
Fabbiano S, Menacho Márquez M, Robles Valero J, Pericacho M, Matesanz Marín A, García Macías C, et al. Immunosuppression-Independent Role of Regulatory T Cells against Hypertension-Driven Renal Dysfunctions. Mol Cell Biol. 2015;35:3528-46 pubmed publisher
Friebe D, Yang T, Schmidt T, Borg N, Steckel B, Ding Z, et al. Purinergic signaling on leukocytes infiltrating the LPS-injured lung. PLoS ONE. 2014;9:e95382 pubmed publisher
Vokaer B, Charbonnier L, Lemaître P, Spilleboudt C, Le Moine A. IL-17A and IL-2-expanded regulatory T cells cooperate to inhibit Th1-mediated rejection of MHC II disparate skin grafts. PLoS ONE. 2013;8:e76040 pubmed publisher
Bönner F, Borg N, Jacoby C, Temme S, Ding Z, Flogel U, et al. Ecto-5'-nucleotidase on immune cells protects from adverse cardiac remodeling. Circ Res. 2013;113:301-12 pubmed publisher
Hackstein H, Wachtendorf A, Kranz S, Lohmeyer J, Bein G, Baal N. Heterogeneity of respiratory dendritic cell subsets and lymphocyte populations in inbred mouse strains. Respir Res. 2012;13:94 pubmed publisher
Regateiro F, Chen Y, Kendal A, Hilbrands R, Adams E, Cobbold S, et al. Foxp3 expression is required for the induction of therapeutic tissue tolerance. J Immunol. 2012;189:3947-56 pubmed publisher
Kinsey G, Huang L, Jaworska K, Khutsishvili K, Becker D, Ye H, et al. Autocrine adenosine signaling promotes regulatory T cell-mediated renal protection. J Am Soc Nephrol. 2012;23:1528-37 pubmed publisher
Bönner F, Borg N, Burghoff S, Schrader J. Resident cardiac immune cells and expression of the ectonucleotidase enzymes CD39 and CD73 after ischemic injury. PLoS ONE. 2012;7:e34730 pubmed publisher
Ehrentraut H, Westrich J, Eltzschig H, Clambey E. Adora2b adenosine receptor engagement enhances regulatory T cell abundance during endotoxin-induced pulmonary inflammation. PLoS ONE. 2012;7:e32416 pubmed publisher
Kachikwu E, Iwamoto K, Liao Y, DeMarco J, Agazaryan N, Economou J, et al. Radiation enhances regulatory T cell representation. Int J Radiat Oncol Biol Phys. 2011;81:1128-35 pubmed publisher
Sun X, Wu Y, Gao W, Enjyoji K, Csizmadia E, Muller C, et al. CD39/ENTPD1 expression by CD4+Foxp3+ regulatory T cells promotes hepatic metastatic tumor growth in mice. Gastroenterology. 2010;139:1030-40 pubmed publisher
Zhou Q, Yan J, Putheti P, Wu Y, Sun X, Toxavidis V, et al. Isolated CD39 expression on CD4+ T cells denotes both regulatory and memory populations. Am J Transplant. 2009;9:2303-11 pubmed publisher
Hyman M, Petrovic Djergovic D, Visovatti S, Liao H, Yanamadala S, Bouïs D, et al. Self-regulation of inflammatory cell trafficking in mice by the leukocyte surface apyrase CD39. J Clin Invest. 2009;119:1136-49 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CD39 Monoclonal Antibody (24DMS1), PE-Cyanine7, eBioscience
Catalog # :
25-0391-82
Quantity :
100 ug
Price :
US 449.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.25 ug/test
Species :
Mouse
Clone :
24DMS1
Isotype :
IgG2b, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
CD39 cell surface antigen is a 70-100kD molecule expressed on peripheral blood B cells, monocytes, T cell clones, and also weakly expressed on granulocytes. CD39 has intrinsic ecto-ATPase activity. Expression of CD39 is induced on T cells and increased on B cells as a late activation antigen.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.25 ug/test
Aliases :
2610206B08Rik; AA408691; ATPDase; Cd39; CD39 antigen; DKFZp686D194; DKFZp686I093; ecto-apyrase; Ecto-ATP diphosphohydrolase 1; ecto-ATPase 1; ecto-ATPDase 1; Ectonucleoside triphosphate diphosphohydrolase 1; ENTPD1; FLJ40921; FLJ40959; Lymphoid cell activation antigen; NTPDase 1; NTPDase-1; SPG64
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA