product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD31 (PECAM-1) Monoclonal Antibody (WM-59 (WM59)), PE-Cyanine7, eBioscience™
catalog :
25-0319-41
quantity :
25 Tests
price :
US 309.00
clonality :
monoclonal
host :
mouse
conjugate :
PE/Cy7
clone name :
WM-59 (WM59)
reactivity :
human
application :
flow cytometry
more info or order :
Invitrogen product webpage
citations: 45
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 1b
Chang S, Kohlgruber A, Mizoguchi F, Michelet X, Wolf B, Wei K, et al. Stromal cell cadherin-11 regulates adipose tissue inflammation and diabetes. J Clin Invest. 2017;127:3300-3312 pubmed publisher
  • flow cytometry; human; fig 3
Kim H, Huang L, Critser P, Yang Z, Chan R, Wang L, et al. Notch ligand Delta-like 1 promotes in vivo vasculogenesis in human cord blood-derived endothelial colony forming cells. Cytotherapy. 2015;17:579-92 pubmed publisher
Zhang B, He L, Liu Y, Zhang J, Zeng Q, Wang S, et al. Prostaglandin E2 Is Required for BMP4-Induced Mesoderm Differentiation of Human Embryonic Stem Cells. Stem Cell Reports. 2018;10:905-919 pubmed publisher
Mizoguchi F, Slowikowski K, Wei K, Marshall J, Rao D, Chang S, et al. Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis. Nat Commun. 2018;9:789 pubmed publisher
Philippeos C, Telerman S, Oulès B, Pisco A, Shaw T, Elgueta R, et al. Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations. J Invest Dermatol. 2018;138:811-825 pubmed publisher
Doll S, Dreßen M, Geyer P, Itzhak D, Braun C, Doppler S, et al. Region and cell-type resolved quantitative proteomic map of the human heart. Nat Commun. 2017;8:1469 pubmed publisher
Bahador M, Gras Navarro A, Rahman M, Dominguez Valentin M, Sarowar S, Ulvestad E, et al. Increased infiltration and tolerised antigen-specific CD8+ TEM cells in tumor but not peripheral blood have no impact on survival of HCMV+ glioblastoma patients. Oncoimmunology. 2017;6:e1336272 pubmed publisher
Li Y, Brauer P, Singh J, Xhiku S, Yoganathan K, Zuniga Pflucker J, et al. Targeted Disruption of TCF12 Reveals HEB as Essential in Human Mesodermal Specification and Hematopoiesis. Stem Cell Reports. 2017;9:779-795 pubmed publisher
Almalki S, Agrawal D. ERK signaling is required for VEGF-A/VEGFR2-induced differentiation of porcine adipose-derived mesenchymal stem cells into endothelial cells. Stem Cell Res Ther. 2017;8:113 pubmed publisher
Almalki S, Llamas Valle Y, Agrawal D. MMP-2 and MMP-14 Silencing Inhibits VEGFR2 Cleavage and Induces the Differentiation of Porcine Adipose-Derived Mesenchymal Stem Cells to Endothelial Cells. Stem Cells Transl Med. 2017;6:1385-1398 pubmed publisher
Pal D, Pertot A, Shirole N, Yao Z, Anaparthy N, Garvin T, et al. TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24- cancer cells. elife. 2017;6: pubmed publisher
Ho J, Lee C, Lin S. No Significant Reduction of Circulating Endothelial-Derived and Platelet-Derived Microparticles in Patients with Psoriasis Successfully Treated with Anti-IL12/23. Biomed Res Int. 2016;2016:3242143 pubmed publisher
Izumi D, Ishimoto T, Miyake K, Sugihara H, Eto K, Sawayama H, et al. CXCL12/CXCR4 activation by cancer-associated fibroblasts promotes integrin β1 clustering and invasiveness in gastric cancer. Int J Cancer. 2016;138:1207-19 pubmed publisher
Gargus M, Niu C, Vallone J, Binkley J, Rubin D, Shaker A. Human esophageal myofibroblasts secrete proinflammatory cytokines in response to acid and Toll-like receptor 4 ligands. Am J Physiol Gastrointest Liver Physiol. 2015;308:G904-23 pubmed
Feng Y, Zhu M, Dangelmajer S, Lee Y, Wijesekera O, Castellanos C, et al. Hypoxia-cultured human adipose-derived mesenchymal stem cells are non-oncogenic and have enhanced viability, motility, and tropism to brain cancer. Cell Death Dis. 2014;5:e1567 pubmed publisher
Yuan K, Orcholski M, Panaroni C, Shuffle E, Huang N, Jiang X, et al. Activation of the Wnt/planar cell polarity pathway is required for pericyte recruitment during pulmonary angiogenesis. Am J Pathol. 2015;185:69-84 pubmed publisher
Park T, Bhutto I, Zimmerlin L, Huo J, Nagaria P, Miller D, et al. Vascular progenitors from cord blood-derived induced pluripotent stem cells possess augmented capacity for regenerating ischemic retinal vasculature. Circulation. 2014;129:359-72 pubmed publisher
Murakami M, Horibe H, Iohara K, Hayashi Y, Osako Y, Takei Y, et al. The use of granulocyte-colony stimulating factor induced mobilization for isolation of dental pulp stem cells with high regenerative potential. Biomaterials. 2013;34:9036-47 pubmed publisher
Yu H, Lee H, Choi H, Ahn J, Choi J, Song H, et al. Characterization of CD45-/CD31+/CD105+ circulating cells in the peripheral blood of patients with gynecologic malignancies. Clin Cancer Res. 2013;19:5340-50 pubmed publisher
Dvergsten J, Mueller R, Griffin P, Abedin S, Pishko A, Michel J, et al. Premature cell senescence and T cell receptor-independent activation of CD8+ T cells in juvenile idiopathic arthritis. Arthritis Rheum. 2013;65:2201-10 pubmed publisher
Azevedo R, Soares M, Albuquerque A, Tendeiro R, Soares R, Martins M, et al. Long-term immune reconstitution of naive and memory t cell pools after haploidentical hematopoietic stem cell transplantation. Biol Blood Marrow Transplant. 2013;19:703-12 pubmed publisher
Ginsberg M, James D, Ding B, Nolan D, Geng F, Butler J, et al. Efficient direct reprogramming of mature amniotic cells into endothelial cells by ETS factors and TGF? suppression. Cell. 2012;151:559-75 pubmed publisher
Fekete N, Rojewski M, Furst D, Kreja L, Ignatius A, Dausend J, et al. GMP-compliant isolation and large-scale expansion of bone marrow-derived MSC. PLoS ONE. 2012;7:e43255 pubmed publisher
Liu R, Ratajczak M. Enumeration of very small embryonic-like stem cells in peripheral blood. Methods Mol Biol. 2012;904:207-19 pubmed publisher
Luo Y, Dallaglio K, Chen Y, Robinson W, Robinson S, McCarter M, et al. ALDH1A isozymes are markers of human melanoma stem cells and potential therapeutic targets. Stem Cells. 2012;30:2100-13 pubmed publisher
Abreu M, Sealy L. Cells expressing the C/EBPbeta isoform, LIP, engulf their neighbors. PLoS ONE. 2012;7:e41807 pubmed publisher
Na I, Wittenbecher F, Dziubianau M, Herholz A, Mensen A, Kunkel D, et al. Rabbit antithymocyte globulin (thymoglobulin) impairs the thymic output of both conventional and regulatory CD4+ T cells after allogeneic hematopoietic stem cell transplantation in adult patients. Haematologica. 2013;98:23-30 pubmed publisher
Park T, Zimmerlin L, Zambidis E. Efficient and simultaneous generation of hematopoietic and vascular progenitors from human induced pluripotent stem cells. Cytometry A. 2013;83:114-26 pubmed publisher
Murakami M, Imabayashi K, Watanabe A, Takeuchi N, Ishizaka R, Iohara K, et al. Identification of novel function of vimentin for quality standard for regenerated pulp tissue. J Endod. 2012;38:920-6 pubmed publisher
Ekser B, Lin C, Long C, Echeverri G, Hara H, Ezzelarab M, et al. Potential factors influencing the development of thrombocytopenia and consumptive coagulopathy after genetically modified pig liver xenotransplantation. Transpl Int. 2012;25:882-96 pubmed publisher
Danova Alt R, Heider A, Egger D, Cross M, Alt R. Very small embryonic-like stem cells purified from umbilical cord blood lack stem cell characteristics. PLoS ONE. 2012;7:e34899 pubmed publisher
Ifergan I, Kebir H, Alvarez J, Marceau G, Bernard M, Bourbonniere L, et al. Central nervous system recruitment of effector memory CD8+ T lymphocytes during neuroinflammation is dependent on ?4 integrin. Brain. 2011;134:3560-77 pubmed publisher
Meyer Zu Hörste M, Ströher E, Berchner Pfannschmidt U, Schmitz Spanke S, Pink M, Gothert J, et al. A novel mechanism involved in the pathogenesis of Graves ophthalmopathy (GO): clathrin is a possible targeting molecule for inhibiting local immune response in the orbit. J Clin Endocrinol Metab. 2011;96:E1727-36 pubmed publisher
Choi H, Kim J, Kwon E, Che J, Lee J, Cho S, et al. Establishment of efficacy and safety assessment of human adipose tissue-derived mesenchymal stem cells (hATMSCs) in a nude rat femoral segmental defect model. J Korean Med Sci. 2011;26:482-91 pubmed publisher
Morse M, McNeel D. Prostate cancer patients on androgen deprivation therapy develop persistent changes in adaptive immune responses. Hum Immunol. 2010;71:496-504 pubmed publisher
Kim W, Sun Y, Do H, Autissier P, Halpern E, Piatak M, et al. Monocyte heterogeneity underlying phenotypic changes in monocytes according to SIV disease stage. J Leukoc Biol. 2010;87:557-67 pubmed publisher
Campeau P, Rafei M, Boivin M, Sun Y, Grabowski G, Galipeau J. Characterization of Gaucher disease bone marrow mesenchymal stromal cells reveals an altered inflammatory secretome. Blood. 2009;114:3181-90 pubmed publisher
Romieu Mourez R, Francois M, Boivin M, Bouchentouf M, Spaner D, Galipeau J. Cytokine modulation of TLR expression and activation in mesenchymal stromal cells leads to a proinflammatory phenotype. J Immunol. 2009;182:7963-73 pubmed publisher
Matthews K, Lim Z, Afzali B, Pearce L, Abdallah A, Kordasti S, et al. Imbalance of effector and regulatory CD4 T cells is associated with graft-versus-host disease after hematopoietic stem cell transplantation using a reduced intensity conditioning regimen and alemtuzumab. Haematologica. 2009;94:956-66 pubmed publisher
Azevedo R, Soares M, Barata J, Tendeiro R, Serra Caetano A, Victorino R, et al. IL-7 sustains CD31 expression in human naive CD4+ T cells and preferentially expands the CD31+ subset in a PI3K-dependent manner. Blood. 2009;113:2999-3007 pubmed publisher
Figueroa Tentori D, Querol S, Dodi I, Madrigal A, Duggleby R. High purity and yield of natural Tregs from cord blood using a single step selection method. J Immunol Methods. 2008;339:228-35 pubmed publisher
Kalkunte S, Lai Z, Tewari N, Chichester C, Romero R, Padbury J, et al. In vitro and in vivo evidence for lack of endovascular remodeling by third trimester trophoblasts. Placenta. 2008;29:871-8 pubmed publisher
Ridgway J, Zhang G, Wu Y, Stawicki S, Liang W, Chanthery Y, et al. Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis. Nature. 2006;444:1083-7 pubmed
Porat Y, Porozov S, Belkin D, Shimoni D, Fisher Y, Belleli A, et al. Isolation of an adult blood-derived progenitor cell population capable of differentiation into angiogenic, myocardial and neural lineages. Br J Haematol. 2006;135:703-14 pubmed
Umeda K, Heike T, Yoshimoto M, Shinoda G, Shiota M, Suemori H, et al. Identification and characterization of hemoangiogenic progenitors during cynomolgus monkey embryonic stem cell differentiation. Stem Cells. 2006;24:1348-58 pubmed
product information
Product Type :
Antibody
Product Name :
CD31 (PECAM-1) Monoclonal Antibody (WM-59 (WM59)), PE-Cyanine7, eBioscience™
Catalog # :
25-0319-41
Quantity :
25 Tests
Price :
US 309.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 5 µL (0.06 µg)/test
Species :
Human
Clone :
WM-59 (WM59)
Isotype :
IgG1, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 5 µL (0.06 µg)/test
Aliases :
C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA