CD13 Monoclonal Antibody (WM-15 (WM15)), PE-Cyanine7, eBioscience | Invitrogen 25-0138-42 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD13 Monoclonal Antibody (WM-15 (WM15)), PE-Cyanine7, eBioscience

catalog :

25-0138-42

quantity :

100 Tests

price :

US 406.00

clonality :

monoclonal

host :

mouse

conjugate :

PE/Cy7

clone name :

WM-15 (WM15)

reactivity :

human

application :

flow cytometry

citations: 12

Reference
Ghashghaei M, Liu Y, Ettles J, Bombaci G, Ramkumar N, Liu Z, et al. Translation efficiency driven by CNOT3 subunit of the CCR4-NOT complex promotes leukemogenesis. Nat Commun. 2024;15:2340 pubmed publisher
Zhao T, Liu S, Hanna N, Jalal S, Ding X, Wan J, et al. LAL deficiency induced myeloid-derived suppressor cells as targets and biomarkers for lung cancer. J Immunother Cancer. 2023;11: pubmed publisher
Sheikh B, Guhathakurta S, Tsang T, Schwabenland M, Renschler G, Herquel B, et al. Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature. Nat Cell Biol. 2020;22:828-841 pubmed publisher
Lin K, Rutter J, Xie A, Pardieu B, Winn E, Bello R, et al. Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer. Nat Genet. 2020;52:408-417 pubmed publisher
Fenouille N, Bassil C, Ben Sahra I, Benajiba L, Alexe G, Ramos A, et al. The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia. Nat Med. 2017;23:301-313 pubmed publisher
Guijarro Muñoz I, Compte M, Álvarez Cienfuegos A, Alvarez Vallina L, Sanz L. Lipopolysaccharide activates Toll-like receptor 4 (TLR4)-mediated NF-?B signaling pathway and proinflammatory response in human pericytes. J Biol Chem. 2014;289:2457-68 pubmed publisher
Zhang K, Chen W, Zhang Y, Ge Y, Ju S, Yang P, et al. An anti-human CD13 monoclonal antibody that suppresses the suppressive function of Treg cells. Monoclon Antib Immunodiagn Immunother. 2013;32:16-20 pubmed publisher
Carnevale J, Ross L, Puissant A, Banerji V, Stone R, DeAngelo D, et al. SYK regulates mTOR signaling in AML. Leukemia. 2013;27:2118-28 pubmed publisher
Zheng Y, Shang B, Li Y, Zhen Y. An NGR-integrated and enediyne-energized apoprotein shows CD13-targeting antitumor activity. Biomed Pharmacother. 2013;67:164-71 pubmed publisher
Reske A, Pollara G, Krummenacher C, Katz D, Chain B. Glycoprotein-dependent and TLR2-independent innate immune recognition of herpes simplex virus-1 by dendritic cells. J Immunol. 2008;180:7525-36 pubmed
Riemann D, Kehlen A, Thiele K, Lohn M, Langner J. Induction of aminopeptidase N/CD13 on human lymphocytes after adhesion to fibroblast-like synoviocytes, endothelial cells, epithelial cells, and monocytes/macrophages. J Immunol. 1997;158:3425-32 pubmed
Look A, Ashmun R, Shapiro L, Peiper S. Human myeloid plasma membrane glycoprotein CD13 (gp150) is identical to aminopeptidase N. J Clin Invest. 1989;83:1299-307 pubmed

product information

Product Type :

Antibody

Product Name :

CD13 Monoclonal Antibody (WM-15 (WM15)), PE-Cyanine7, eBioscience

Catalog # :

25-0138-42

Quantity :

100 Tests

Price :

US 406.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (0.5 ug)/test

Species :

Human

Clone :

WM-15 (WM15)

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

CD13 (ANPEP) is a 150-170 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types. CD13 is a metalloprotease that preferentially catalyzes removal of neutral amino acids from small peptides, thus activating or inactivating bioactive peptides. CD13 also has a role in extracellular matrix degradation, antigen processing and signal transduction, is important in inflammatory responses, regulates intercellular contact, cell motility and vascularization. CD13 is expressed by granulocytes, monocytes, myeloid leukemia cells, and is involved in protection of leukemic cells against apoptosis and its expression associated with poor prognosis of carcinomas. CD13 functions as an aminopeptidase enzyme and is also alpha receptor for coronavirus.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (0.5 ug)/test

Aliases :

alanyl (membrane) aminopeptidase; alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150); alanyl aminopeptidase; alanyl aminopeptidase, membrane; aminopeptidase; aminopeptidase Ey; Aminopeptidase M; aminopeptidase N; aminopeptidase N.; aminopeptidase N/CD13; Anpep; APDE; Apm; AP-M; APN; AP-N; bAPN; cAPN; Cd13; cluster of differentiation antigen 13 (CD13); fAPN; gp130; gp150; h AP-N; hAPN; kidney aminopeptidase M; kidney Zn peptidase; KZP; Lap1; Lap-1; leucine arylaminopeptidase 1; LOW QUALITY PROTEIN: aminopeptidase N; membrane alanine aminiopeptidase; membrane alanine aminopeptidase; membrane alanyl aminopeptidase; membrane protein p161; Microsomal aminopeptidase; myeloid plasma membrane glycoprotein CD13; p150; pAPN; PEPN; porcine aminopeptidase N; rAPN; rbAPN; Unknown (protein for MGC:126949)