CD5 Monoclonal Antibody (53-7.3), PE-Cyanine7, eBioscience™ | Invitrogen 25-0051-81 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD5 Monoclonal Antibody (53-7.3), PE-Cyanine7, eBioscience™

catalog :

25-0051-81

quantity :

50 µg

price :

US 235

clonality :

monoclonal

host :

rat

conjugate :

PE/Cy7

clone name :

53-7.3

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 25

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 2b, 7c, 7d, 7e	Lu L, Li T, Feng X, Liu Z, Liu Y, Chao T, et al. Excessive immunosuppression by regulatory T cells antagonizes T cell response to schistosome infection in PD-1-deficient mice. PLoS Pathog. 2022;18:e1010596 pubmed publisher
flow cytometry; mouse; 1:200; tbl 1	Jackson Jones L, Duncan S, Magalhaes M, Campbell S, Maizels R, McSorley H, et al. Fat-associated lymphoid clusters control local IgM secretion during pleural infection and lung inflammation. Nat Commun. 2016;7:12651 pubmed publisher
flow cytometry; mouse	Chen S, Chang B, Chang S, Tong T, Ham S, Sherry B, et al. BTK inhibition results in impaired CXCR4 chemokine receptor surface expression, signaling and function in chronic lymphocytic leukemia. Leukemia. 2016;30:833-43 pubmed publisher
flow cytometry; mouse	Weber G, Chousterman B, Hilgendorf I, Robbins C, Theurl I, Gerhardt L, et al. Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis. J Exp Med. 2014;211:1243-56 pubmed publisher
flow cytometry; mouse; fig 2	Nussbaum J, Van Dyken S, von Moltke J, Cheng L, Mohapatra A, Molofsky A, et al. Type 2 innate lymphoid cells control eosinophil homeostasis. Nature. 2013;502:245-8 pubmed publisher
	Azam Z, Sapra L, Baghel K, Sinha N, Gupta R, Soni V, et al. Cissus quadrangularis (Hadjod) Inhibits RANKL-Induced Osteoclastogenesis and Augments Bone Health in an Estrogen-Deficient Preclinical Model of Osteoporosis Via Modulating the Host Osteoimmune System. Cells. 2023;12: pubmed publisher
	Sapra L, Shokeen N, Porwal K, Saini C, Bhardwaj A, Mathew M, et al. Bifidobacterium longum Ameliorates Ovariectomy-Induced Bone Loss via Enhancing Anti-Osteoclastogenic and Immunomodulatory Potential of Regulatory B Cells (Bregs). Front Immunol. 2022;13:875788 pubmed publisher
	Ercoli G, Ramos Sevillano E, Nakajima R, de Assis R, Jasinskas A, Goldblatt D, et al. The Influence of B Cell Depletion Therapy on Naturally Acquired Immunity to Streptococcus pneumoniae. Front Immunol. 2020;11:611661 pubmed publisher
	New J, Dizon B, Fucile C, Rosenberg A, Kearney J, King R. Neonatal Exposure to Commensal-Bacteria-Derived Antigens Directs Polysaccharide-Specific B-1 B Cell Repertoire Development. Immunity. 2020;53:172-186.e6 pubmed publisher
	Khiew S, Jain D, Chen J, Yang J, Yin D, Young J, et al. Transplantation tolerance modifies donor-specific B cell fate to suppress de novo alloreactive B cells. J Clin Invest. 2020;130:3453-3466 pubmed publisher
	Walker J, Clark P, Crisp A, Barlow J, Szeto A, Ferreira A, et al. Polychromic Reporter Mice Reveal Unappreciated Innate Lymphoid Cell Progenitor Heterogeneity and Elusive ILC3 Progenitors in Bone Marrow. Immunity. 2019;: pubmed publisher
	Moretti F, Klapproth S, Ruppert R, Margraf A, Weber J, Pick R, et al. Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus. elife. 2018;7: pubmed publisher
	Niemeyer B, Oko L, Medina E, Oldenburg D, White D, Cool C, et al. Host Tumor Suppressor p18INK4c Functions as a Potent Cell-Intrinsic Inhibitor of Murine Gammaherpesvirus 68 Reactivation and Pathogenesis. J Virol. 2018;92: pubmed publisher
	Ren G, Jin W, Cui K, Rodrigez J, Hu G, Zhang Z, et al. CTCF-Mediated Enhancer-Promoter Interaction Is a Critical Regulator of Cell-to-Cell Variation of Gene Expression. Mol Cell. 2017;67:1049-1058.e6 pubmed publisher
	Freitas C, Hamblin G, Raymond C, Weber K. Naïve helper T cells with high CD5 expression have increased calcium signaling. PLoS ONE. 2017;12:e0178799 pubmed publisher
	Alrefai H, Muhammad K, Rudolf R, Pham D, Klein Hessling S, Patra A, et al. NFATc1 supports imiquimod-induced skin inflammation by suppressing IL-10 synthesis in B cells. Nat Commun. 2016;7:11724 pubmed publisher
	Lykken J, Horikawa M, Minard Colin V, Kamata M, Miyagaki T, Poe J, et al. Galectin-1 drives lymphoma CD20 immunotherapy resistance: validation of a preclinical system to identify resistance mechanisms. Blood. 2016;127:1886-95 pubmed publisher
	Rak G, Osborne L, Siracusa M, Kim B, Wang K, Bayat A, et al. IL-33-Dependent Group 2 Innate Lymphoid Cells Promote Cutaneous Wound Healing. J Invest Dermatol. 2016;136:487-496 pubmed publisher
	Stitelman D, Brazelton T, Bora A, Traas J, Merianos D, Limberis M, et al. Developmental stage determines efficiency of gene transfer to muscle satellite cells by in utero delivery of adeno-associated virus vector serotype 2/9. Mol Ther Methods Clin Dev. 2014;1:14040 pubmed publisher
	Weber G. Immune targeting of the pleural space by intercostal approach. BMC Pulm Med. 2015;15:14 pubmed publisher
	Pone E, Lam T, Lou Z, Wang R, Chen Y, Liu D, et al. B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses. J Immunol. 2015;194:3065-78 pubmed publisher
	Mion F, D IncÃ F, Danelli L, Toffoletto B, Guarnotta C, Frossi B, et al. Mast cells control the expansion and differentiation of IL-10-competent B cells. J Immunol. 2014;193:4568-79 pubmed publisher
	Jeong Y, Hong S, Cho S, Lee W, Lee S. Induction of IL-10-producing CD1dhighCD5+ regulatory B cells following Babesia microti-infection. PLoS ONE. 2012;7:e46553 pubmed publisher
	Sestero C, McGuire D, De Sarno P, Brantley E, Soldevila G, Axtell R, et al. CD5-dependent CK2 activation pathway regulates threshold for T cell anergy. J Immunol. 2012;189:2918-30 pubmed publisher
	Sanchez Aguilera A, Rattmann I, Drew D, Müller L, Summey V, Lucas D, et al. Involvement of RhoH GTPase in the development of B-cell chronic lymphocytic leukemia. Leukemia. 2010;24:97-104 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD5 Monoclonal Antibody (53-7.3), PE-Cyanine7, eBioscience™

Catalog # :

25-0051-81

Quantity :

50 µg

Price :

US 235

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.25 µg/test

Species :

Mouse

Clone :

53-7.3

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein. CD5 is present on all mature T-lymphocytes, on most of thymocytes and on many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor in regulating T-cell proliferation. CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by many T cell leukemia, lymphomas, and activated T cells. Diseases associated with CD5 dysfunction include thymus cancer and Richter's Syndrome.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 µg/test

Aliases :

CD antigen CD5; CD5; CD5 antigen; CD5 antigen (p56-62); CD5 antigen p56-62; Cd5 molecule; CD5 protein; CD74 antigen, invariant polypeptide of major; fCD5; LEU1; Ly-1; Ly-12; Ly-A; Lymphocyte antigen 1; Lymphocyte antigen CD5; lymphocyte antigen T1/Leu-1; Lyt-1; Pan T cell; T1; T-cell surface glycoprotein CD5; unnamed protein product

more info or order :

Invitrogen product webpage