| Reference |
|---|
Sprooten J, Vanmeerbeek I, Datsi A, Govaerts J, Naulaerts S, Laureano R, et al. Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells. Cell Rep Med. 2024;5:101377 pubmed publisher |
Chen M, Peng Q, Tan Z, Xu S, Wang Y, Wu A, et al. Targeting Aquaporin-3 Attenuates Skin Inflammation in Rosacea. Int J Biol Sci. 2023;19:5160-5173 pubmed publisher |
Lim Y, Yoon G, Ryu Y, Jeong D, Song J, Kim Y, et al. Human lncRNA SUGCT-AS1 Regulates the Proinflammatory Response of Macrophage. Int J Mol Sci. 2023;24: pubmed publisher |
Kiss M, Mindur J, Yates A, Lee D, Fullard J, Anzai A, et al. Interleukin-3 coordinates glial-peripheral immune crosstalk to incite multiple sclerosis. Immunity. 2023;56:1502-1514.e8 pubmed publisher |
Liu K, Gao Y, Xiao W, Fu J, Huang S, Han X, et al. Multidimensional Analysis of Lung Lymph Nodes in a Mouse Model of Allergic Lung Inflammation following PM2.5 and Indeno[1,2,3-cd]pyrene Exposure. Environ Health Perspect. 2023;131:37014 pubmed publisher |
Agrafiotis A, Neumeier D, Hong K, Chowdhury T, Ehling R, Kuhn R, et al. Generation of a single-cell B cell atlas of antibody repertoires and transcriptomes to identify signatures associated with antigen specificity. iScience. 2023;26:106055 pubmed publisher |
Yang W, Qiu W, Zhang T, Xu K, Gu Z, Zhou Y, et al. Nsun2 coupling with RoRγt shapes the fate of Th17 cells and promotes colitis. Nat Commun. 2023;14:863 pubmed publisher |
Gurska L, Okabe R, Schurer A, Tong M, Soto M, Choi D, et al. Crizotinib Has Preclinical Efficacy in Philadelphia-Negative Myeloproliferative Neoplasms. Clin Cancer Res. 2023;29:943-956 pubmed publisher |
Wang Y, Sansone A, Smirnov A, Stallings C, Orvedahl A. Myeloid autophagy genes protect mice against fatal TNF- and LPS-induced cytokine storm syndromes. Autophagy. 2023;19:1114-1127 pubmed publisher |
Tajima M, Strober W. Evaluation of Glutaminolysis in T Cells. Curr Protoc. 2022;2:e540 pubmed publisher |
Liu Y, Li Q, Alikarami F, Barrett D, Mahdavi L, Li H, et al. Small-Molecule Inhibition of the Acyl-Lysine Reader ENL as a Strategy against Acute Myeloid Leukemia. Cancer Discov. 2022;12:2684-2709 pubmed publisher |
Vrij E, Scholte Op Reimer Y, Roa Fuentes L, Misteli Guerreiro I, Holzmann V, Frias Aldeguer J, et al. A pendulum of induction between the epiblast and extra-embryonic endoderm supports post-implantation progression. Development. 2022;149: pubmed publisher |
Lee A, Feng E, Chew M, Balint E, Poznanski S, Giles E, et al. Type I interferon regulates proteolysis by macrophages to prevent immunopathology following viral infection. PLoS Pathog. 2022;18:e1010471 pubmed publisher |
Colombo G, Travelli C, Porta C, Genazzani A. Extracellular nicotinamide phosphoribosyltransferase boosts IFNγ-induced macrophage polarization independently of TLR4. iScience. 2022;25:104147 pubmed publisher |
Hochrein S, Wu H, Eckstein M, Arrigoni L, Herman J, Schumacher F, et al. The glucose transporter GLUT3 controls T helper 17 cell responses through glycolytic-epigenetic reprogramming. Cell Metab. 2022;34:516-532.e11 pubmed publisher |
Gadomski S, Fielding C, Garc xed a Garc xed a A, Korn C, Kapeni C, Ashraf S, et al. A cholinergic neuroskeletal interface promotes bone formation during postnatal growth and exercise. Cell Stem Cell. 2022;29:528-544.e9 pubmed publisher |
Ahmed N, Etzrodt M, Dettinger P, Kull T, Loeffler D, Hoppe P, et al. Blood stem cell PU.1 upregulation is a consequence of differentiation without fast autoregulation. J Exp Med. 2022;219: pubmed publisher |
Neumeier D, Pedrioli A, Genovese A, Sandu I, Ehling R, Hong K, et al. Profiling the specificity of clonally expanded plasma cells during chronic viral infection by single-cell analysis. Eur J Immunol. 2022;52:297-311 pubmed publisher |
Jiang L, Yang M, He S, Li Z, Li H, Niu T, et al. MMP12 knockout prevents weight and muscle loss in tumor-bearing mice. BMC Cancer. 2021;21:1297 pubmed publisher |
Wilfahrt D, Philips R, Lama J, Kizerwetter M, Shapiro M, McCue S, et al. Histone deacetylase 3 represses cholesterol efflux during CD4+ T-cell activation. elife. 2021;10: pubmed publisher |
Shen Y, Jiang L, Iyer V, Raposo B, Dubnovitsky A, Boddul S, et al. A rapid CRISPR competitive assay for in vitro and in vivo discovery of potential drug targets affecting the hematopoietic system. Comput Struct Biotechnol J. 2021;19:5360-5370 pubmed publisher |
Pescador N, Francisco V, V xe1 zquez P, Esquinas E, Gonz xe1 lez P xe1 ramos C, Valdecantos M, et al. Metformin reduces macrophage HIF1α-dependent proinflammatory signaling to restore brown adipocyte function in vitro. Redox Biol. 2021;48:102171 pubmed publisher |
Stamos D, Clubb L, Mitra A, Chopp L, Nie J, Ding Y, et al. The histone demethylase Lsd1 regulates multiple repressive gene programs during T cell development. J Exp Med. 2021;218: pubmed publisher |
Kiritsy M, McCann K, MOTT D, Holland S, Behar S, Sassetti C, et al. Mitochondrial respiration contributes to the interferon gamma response in antigen-presenting cells. elife. 2021;10: pubmed publisher |
Spiljar M, Steinbach K, Rigo D, Su xe1 rez Zamorano N, Wagner I, Hadadi N, et al. Cold exposure protects from neuroinflammation through immunologic reprogramming. Cell Metab. 2021;33:2231-2246.e8 pubmed publisher |
Karki R, Sundaram B, Sharma B, Lee S, Malireddi R, Nguyen L, et al. ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis. Cell Rep. 2021;37:109858 pubmed publisher |
Guo B, Peng Y, Gu Y, Zhong Y, Su C, Liu L, et al. Resveratrol pretreatment mitigates LPS-induced acute lung injury by regulating conventional dendritic cells' maturation and function. Open Life Sci. 2021;16:1064-1081 pubmed publisher |
Jang Y, Song H, Seo G, Jo H, Park S, Park H, et al. Lactoferrin Potentiates Inducible Regulatory T Cell Differentiation through TGF-β Receptor III Binding and Activation of Membrane-Bound TGF-β. J Immunol. 2021;207:2456-2464 pubmed publisher |
Zhao X, Liu J, Zhang C, Yu N, Lu Z, Zhang S, et al. Porphyromonas gingivalis exacerbates ulcerative colitis via Porphyromonas gingivalis peptidylarginine deiminase. Int J Oral Sci. 2021;13:31 pubmed publisher |
Chi X, Jin W, Bai X, Zhao X, Shao J, Li J, et al. RORα is critical for mTORC1 activity in T cell-mediated colitis. Cell Rep. 2021;36:109682 pubmed publisher |
Khateb A, Deshpande A, Feng Y, Finlay D, Lee J, Lazar I, et al. The ubiquitin ligase RNF5 determines acute myeloid leukemia growth and susceptibility to histone deacetylase inhibitors. Nat Commun. 2021;12:5397 pubmed publisher |
Yamada H, Saegusa J, Sendo S, Ueda Y, Okano T, Shinohara M, et al. Effect of resolvin D5 on T cell differentiation and osteoclastogenesis analyzed by lipid mediator profiling in the experimental arthritis. Sci Rep. 2021;11:17312 pubmed publisher |
Flommersfeld S, B xf6 ttcher J, Ersching J, Flossdorf M, Meiser P, Pachmayr L, et al. Fate mapping of single NK cells identifies a type 1 innate lymphoid-like lineage that bridges innate and adaptive recognition of viral infection. Immunity. 2021;54:2288-2304.e7 pubmed publisher |
Qian Y, Arellano G, Ifergan I, Lin J, Snowden C, Kim T, et al. ZEB1 promotes pathogenic Th1 and Th17 cell differentiation in multiple sclerosis. Cell Rep. 2021;36:109602 pubmed publisher |
Wang F, Li Z, Zhou J, Wang G, Zhang W, Xu J, et al. SIRT1 regulates the phosphorylation and degradation of P27 by deacetylating CDK2 to promote T-cell acute lymphoblastic leukemia progression. J Exp Clin Cancer Res. 2021;40:259 pubmed publisher |
Luo M, Lai W, He Z, Wu L. Development of an Optimized Culture System for Generating Mouse Alveolar Macrophage-like Cells. J Immunol. 2021;207:1683-1693 pubmed publisher |
Ahirwar D, Charan M, Mishra S, Verma A, Shilo K, Ramaswamy B, et al. Slit2 Inhibits Breast Cancer Metastasis by Activating M1-Like Phagocytic and Antifibrotic Macrophages. Cancer Res. 2021;81:5255-5267 pubmed publisher |
Yu S, Tripod M, Atasoy U, Chen J. HuR Plays a Positive Role to Strengthen the Signaling Pathways of CD4+ T Cell Activation and Th17 Cell Differentiation. J Immunol Res. 2021;2021:9937243 pubmed publisher |
Nguyen G, Xu S, Adams W, Leong J, Bunnell S, Mansour M, et al. Neutrophils require SKAP2 for reactive oxygen species production following C-type lectin and Candida stimulation. iScience. 2021;24:102871 pubmed publisher |
Roberto M, Varano G, Viñas Castells R, Holmes A, Kumar R, Pasqualucci L, et al. Mutations in the transcription factor FOXO1 mimic positive selection signals to promote germinal center B cell expansion and lymphomagenesis. Immunity. 2021;54:1807-1824.e14 pubmed publisher |
Adlung L, Stapor P, T xf6 nsing C, Schmiester L, Schwarzm xfc ller L, Postawa L, et al. Cell-to-cell variability in JAK2/STAT5 pathway components and cytoplasmic volumes defines survival threshold in erythroid progenitor cells. Cell Rep. 2021;36:109507 pubmed publisher |
Orellana E, Liu Q, Yankova E, Pirouz M, De Braekeleer E, Zhang W, et al. METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation. Mol Cell. 2021;: pubmed publisher |
Kim G, Kim W, Lim S, Lee H, Koo J, Nam K, et al. In Vivo Induction of Regulatory T Cells Via CTLA-4 Signaling Peptide to Control Autoimmune Encephalomyelitis and Prevent Disease Relapse. Adv Sci (Weinh). 2021;8:2004973 pubmed publisher |
He J, Shangguan X, Zhou W, Cao Y, Zheng Q, Tu J, et al. Glucose limitation activates AMPK coupled SENP1-Sirt3 signalling in mitochondria for T cell memory development. Nat Commun. 2021;12:4371 pubmed publisher |
Agarwal P, Li H, Choi K, Hueneman K, He J, Welner R, et al. TNF-α-induced alterations in stromal progenitors enhance leukemic stem cell growth via CXCR2 signaling. Cell Rep. 2021;36:109386 pubmed publisher |
Puleston D, Baixauli F, Sanin D, Edwards Hicks J, Villa M, Kabat A, et al. Polyamine metabolism is a central determinant of helper T cell lineage fidelity. Cell. 2021;184:4186-4202.e20 pubmed publisher |
Yang L, Chan A, Miyashita K, Delaney C, Wang X, Li H, et al. High-resolution characterization of gene function using single-cell CRISPR tiling screen. Nat Commun. 2021;12:4063 pubmed publisher |
AbuEid M, McAllister D, McOlash L, Harwig M, Cheng G, Drouillard D, et al. Synchronous effects of targeted mitochondrial complex I inhibitors on tumor and immune cells abrogate melanoma progression. iScience. 2021;24:102653 pubmed publisher |
Debackere K, Marcelis L, Demeyer S, Vanden Bempt M, Mentens N, Gielen O, et al. Fusion transcripts FYN-TRAF3IP2 and KHDRBS1-LCK hijack T cell receptor signaling in peripheral T-cell lymphoma, not otherwise specified. Nat Commun. 2021;12:3705 pubmed publisher |
Di Marcantonio D, Martinez E, Kanefsky J, Huhn J, Gabbasov R, Gupta A, et al. ATF3 coordinates serine and nucleotide metabolism to drive cell cycle progression in acute myeloid leukemia. Mol Cell. 2021;81:2752-2764.e6 pubmed publisher |
Sonoda S, Murata S, Kato H, Zakaria F, Kyumoto Nakamura Y, Uehara N, et al. Targeting of Deciduous Tooth Pulp Stem Cell-Derived Extracellular Vesicles on Telomerase-Mediated Stem Cell Niche and Immune Regulation in Systemic Lupus Erythematosus. J Immunol. 2021;206:3053-3063 pubmed publisher |
Zheng J, MEYERHOLZ D, Wong L, Gelb M, Murakami M, Perlman S. Coronavirus-specific antibody production in middle-aged mice requires phospholipase A2G2D. J Clin Invest. 2021;131: pubmed publisher |
Bian Z, Shi L, Kidder K, Zen K, Garnett Benson C, Liu Y. Intratumoral SIRPα-deficient macrophages activate tumor antigen-specific cytotoxic T cells under radiotherapy. Nat Commun. 2021;12:3229 pubmed publisher |
Li M, Yan Y, Zhang X, Zhang Y, Xu X, Zhang L, et al. Scaffold compound L971 exhibits anti-inflammatory activities through inhibition of JAK/STAT and NFκB signalling pathways. J Cell Mol Med. 2021;: pubmed publisher |
Supper E, Rudat S, Iyer V, Droop A, Wong K, Spinella J, et al. Cut-like homeobox 1 (CUX1) tumor suppressor gene haploinsufficiency induces apoptosis evasion to sustain myeloid leukemia. Nat Commun. 2021;12:2482 pubmed publisher |
Qu J, Yang Z. Protocol to produce high-titer retrovirus for transduction of mouse bone marrow cells. STAR Protoc. 2021;2:100459 pubmed publisher |
Dikiy S, Li J, Bai L, Jiang M, Janke L, Zong X, et al. A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance. Immunity. 2021;54:931-946.e11 pubmed publisher |
Zheng W, Song H, Luo Z, Wu H, Chen L, Wang Y, et al. Acetylcholine ameliorates colitis by promoting IL-10 secretion of monocytic myeloid-derived suppressor cells through the nAChR/ERK pathway. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher |
Baba T, Yoshida T, Tanabe Y, Nishimura T, Morishita S, Gotoh N, et al. Cytoplasmic DNA accumulation preferentially triggers cell death of myeloid leukemia cells by interacting with intracellular DNA sensing pathway. Cell Death Dis. 2021;12:322 pubmed publisher |
Thomas M, Abdelhamed S, Hiltenbrand R, Schwartz J, Sakurada S, Walsh M, et al. Pediatric MDS and bone marrow failure-associated germline mutations in SAMD9 and SAMD9L impair multiple pathways in primary hematopoietic cells. Leukemia. 2021;35:3232-3244 pubmed publisher |
Lv K, Gong C, Antony C, Han X, Ren J, Donaghy R, et al. HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis. Cell Stem Cell. 2021;28:1275-1290.e9 pubmed publisher |
Buffolo F, Petrosino V, Albini M, Moschetta M, Carlini F, Floss T, et al. Neuroinflammation induces synaptic scaling through IL-1β-mediated activation of the transcriptional repressor REST/NRSF. Cell Death Dis. 2021;12:180 pubmed publisher |
Mei Y, Wang M, Lu G, Li J, Peng L, Lang Y, et al. Postponing tumor onset and tumor progression can be achieved by alteration of local tumor immunity. Cancer Cell Int. 2021;21:97 pubmed publisher |
Klawonn A, Fritz M, Castany S, Pignatelli M, Canal C, Similä F, et al. Microglial activation elicits a negative affective state through prostaglandin-mediated modulation of striatal neurons. Immunity. 2021;54:225-234.e6 pubmed publisher |
Kiuchi M, Onodera A, Kokubo K, Ichikawa T, Morimoto Y, Kawakami E, et al. The Cxxc1 subunit of the Trithorax complex directs epigenetic licensing of CD4+ T cell differentiation. J Exp Med. 2021;218: pubmed publisher |
He L, Wang L, Zeng H, Tan P, Ma G, Zheng S, et al. Engineering of a bona fide light-operated calcium channel. Nat Commun. 2021;12:164 pubmed publisher |
Latif A, Newcombe A, Li S, Gilroy K, Robertson N, Lei X, et al. BRD4-mediated repression of p53 is a target for combination therapy in AML. Nat Commun. 2021;12:241 pubmed publisher |
Dey A, Gonon A, P xe9 cheur E, Pezet M, Villiers C, Marche P. Impact of Gold Nanoparticles on the Functions of Macrophages and Dendritic Cells. Cells. 2021;10: pubmed publisher |
Permanyer M, Bosnjak B, Glage S, Friedrichsen M, Floess S, Huehn J, et al. Efficient IL-2R signaling differentially affects the stability, function, and composition of the regulatory T-cell pool. Cell Mol Immunol. 2021;18:398-414 pubmed publisher |
Sun Y, Zhou Y, Shi Y, Zhang Y, Liu K, Liang R, et al. Expression of miRNA-29 in Pancreatic β Cells Promotes Inflammation and Diabetes via TRAF3. Cell Rep. 2021;34:108576 pubmed publisher |
Yabe R, Chung S, Murayama M, Kubo S, Shimizu K, Akahori Y, et al. TARM1 contributes to development of arthritis by activating dendritic cells through recognition of collagens. Nat Commun. 2021;12:94 pubmed publisher |
Xu N, Palmer D, Robeson A, Shou P, Bommiasamy H, Laurie S, et al. STING agonist promotes CAR T cell trafficking and persistence in breast cancer. J Exp Med. 2021;218: pubmed publisher |
Nagamachi A, Kanai A, Nakamura M, Okuda H, Yokoyama A, Shinriki S, et al. Multiorgan failure with abnormal receptor metabolism in mice mimicking Samd9/9L syndromes. J Clin Invest. 2021;131: pubmed publisher |
Karki R, Sharma B, Tuladhar S, Williams E, Zalduondo L, Samir P, et al. Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes. Cell. 2021;184:149-168.e17 pubmed publisher |
Almeida L, Dhillon LaBrooy A, Castro C, Adossa N, Carriche G, Guderian M, et al. Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis. Immunity. 2021;54:68-83.e6 pubmed publisher |
Tyrrell D, Blin M, Song J, Wood S, Goldstein D. Aging Impairs Mitochondrial Function and Mitophagy and Elevates Interleukin 6 Within the Cerebral Vasculature. J Am Heart Assoc. 2020;9:e017820 pubmed publisher |
Kong H, Reczek C, McElroy G, Steinert E, Wang T, Sabatini D, et al. Metabolic determinants of cellular fitness dependent on mitochondrial reactive oxygen species. Sci Adv. 2020;6: pubmed publisher |
Cerezo Wallis D, Contreras Alcalde M, Troulé K, Catena X, Mucientes C, Calvo T, et al. Midkine rewires the melanoma microenvironment toward a tolerogenic and immune-resistant state. Nat Med. 2020;26:1865-1877 pubmed publisher |
Kidder K, Bian Z, Shi L, Liu Y. Inflammation Unrestrained by SIRPα Induces Secondary Hemophagocytic Lymphohistiocytosis Independent of IFN-γ. J Immunol. 2020;205:2821-2833 pubmed publisher |
Browning L, Miller C, Kuczma M, Pietrzak M, Jing Y, Rempala G, et al. Bone Morphogenic Proteins Are Immunoregulatory Cytokines Controlling FOXP3+ Treg Cells. Cell Rep. 2020;33:108219 pubmed publisher |
Wong R, Belk J, Govero J, Uhrlaub J, Reinartz D, Zhao H, et al. Affinity-Restricted Memory B Cells Dominate Recall Responses to Heterologous Flaviviruses. Immunity. 2020;53:1078-1094.e7 pubmed publisher |
Xu C, Wang L, Fozouni P, Evjen G, Chandra V, Jiang J, et al. SIRT1 is downregulated by autophagy in senescence and ageing. Nat Cell Biol. 2020;22:1170-1179 pubmed publisher |
Xiao Y, Qureischi M, Dietz L, Vaeth M, Vallabhapurapu S, Klein Hessling S, et al. Lack of NFATc1 SUMOylation prevents autoimmunity and alloreactivity. J Exp Med. 2021;218: pubmed publisher |
Piseddu I, R xf6 hrle N, Knott M, Moder S, Eiber S, Schnell K, et al. Constitutive Expression of CCL22 Is Mediated by T Cell-Derived GM-CSF. J Immunol. 2020;205:2056-2065 pubmed publisher |
Bromley S, Akbaba H, Mani V, Mora Buch R, Chasse A, Sama A, et al. CD49a Regulates Cutaneous Resident Memory CD8+ T Cell Persistence and Response. Cell Rep. 2020;32:108085 pubmed publisher |
Tan J, Liu H, Huang M, Li N, Tang S, Meng J, et al. Small molecules targeting RORγt inhibit autoimmune disease by suppressing Th17 cell differentiation. Cell Death Dis. 2020;11:697 pubmed publisher |
Chang D, Xing Q, Su Y, Zhao X, Xu W, Wang X, et al. The Conserved Non-coding Sequences CNS6 and CNS9 Control Cytokine-Induced Rorc Transcription during T Helper 17 Cell Differentiation. Immunity. 2020;53:614-626.e4 pubmed publisher |
Gleitz H, Dugourd A, Leimkühler N, Snoeren I, Fuchs S, Menzel S, et al. Increased CXCL4 expression in hematopoietic cells links inflammation and progression of bone marrow fibrosis in MPN. Blood. 2020;136:2051-2064 pubmed publisher |
Kim D, Nguyen Q, Lee J, Lee S, Janocha A, Kim S, et al. Anti-inflammatory Roles of Glucocorticoids Are Mediated by Foxp3+ Regulatory T Cells via a miR-342-Dependent Mechanism. Immunity. 2020;53:581-596.e5 pubmed publisher |
Bachmann M, Lamprecht L, Gonther S, Pfeilschifter J, Muhl H. A murine cellular model of necroinflammation displays RAGE-dependent cytokine induction that connects to hepatoma cell injury. J Cell Mol Med. 2020;: pubmed publisher |
Yan J, Hedl M, Abraham C. Myeloid Cell-Intrinsic IRF5 Promotes T Cell Responses through Multiple Distinct Checkpoints In Vivo, and IRF5 Immune-Mediated Disease Risk Variants Modulate These Myeloid Cell Functions. J Immunol. 2020;205:1024-1038 pubmed publisher |
Pessoa Rodrigues C, Herman J, Herquel B, Valsecchi C, Stehle T, Grün D, et al. Temporal expression of MOF acetyltransferase primes transcription factor networks for erythroid fate. Sci Adv. 2020;6:eaaz4815 pubmed publisher |
Consiglio C, Udartseva O, Ramsey K, Bush C, Gollnick S. Enzalutamide, an Androgen Receptor Antagonist, Enhances Myeloid Cell-Mediated Immune Suppression and Tumor Progression. Cancer Immunol Res. 2020;8:1215-1227 pubmed publisher |
Zhang Y, Guo Y, Gough S, Zhang J, Vann K, Li K, et al. Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion. Nat Commun. 2020;11:3339 pubmed publisher |
Kahlfuss S, Kaufmann U, Concepcion A, Noyer L, Raphael D, Vaeth M, et al. STIM1-mediated calcium influx controls antifungal immunity and the metabolic function of non-pathogenic Th17 cells. EMBO Mol Med. 2020;12:e11592 pubmed publisher |
Li Z, He C, Zhang J, Zhang H, Wei H, Wu S, et al. P2Y6 Deficiency Enhances Dendritic Cell-Mediated Th1/Th17 Differentiation and Aggravates Experimental Autoimmune Encephalomyelitis. J Immunol. 2020;205:387-397 pubmed publisher |
Numata A, Kwok H, Zhou Q, Li J, Tirado Magallanes R, Angarica V, et al. Lysine acetyltransferase Tip60 is required for hematopoietic stem cell maintenance. Blood. 2020;136:1735-1747 pubmed publisher |
Schick J, Schafer J, Alexander C, Dichtl S, Murray P, Christensen D, et al. Cutting Edge: TNF Is Essential for Mycobacteria-Induced MINCLE Expression, Macrophage Activation, and Th17 Adjuvanticity. J Immunol. 2020;205:323-328 pubmed publisher |
Meyer L, Verbist K, Albeituni S, Scull B, Bassett R, Stroh A, et al. JAK/STAT pathway inhibition sensitizes CD8 T cells to dexamethasone-induced apoptosis in hyperinflammation. Blood. 2020;136:657-668 pubmed publisher |
Matthias J, Heink S, Picard F, Zeiträg J, Kolz A, Chao Y, et al. Salt generates antiinflammatory Th17 cells but amplifies pathogenicity in proinflammatory cytokine microenvironments. J Clin Invest. 2020;130:4587-4600 pubmed publisher |
Mikami N, Kawakami R, Chen K, Sugimoto A, Ohkura N, Sakaguchi S. Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation. Proc Natl Acad Sci U S A. 2020;117:12258-12268 pubmed publisher |
Morianos I, Trochoutsou A, Papadopoulou G, Semitekolou M, Banos A, Konstantopoulos D, et al. Activin-A limits Th17 pathogenicity and autoimmune neuroinflammation via CD39 and CD73 ectonucleotidases and Hif1-α-dependent pathways. Proc Natl Acad Sci U S A. 2020;117:12269-12280 pubmed publisher |
Qi H, Tian D, Li M, Zhang C, Jin H, Liu L, et al. Foxo3 Promotes the Differentiation and Function of Follicular Helper T Cells. Cell Rep. 2020;31:107621 pubmed publisher |
Zhang Z, Huang X, Wang E, Huang Y, Yang R. Suppression of Mll1-Complex by Stat3/Cebpβ-Induced miR-21a/21b/181b Maintains the Accumulation, Homeostasis, and Immunosuppressive Function of Polymorphonuclear Myeloid-Derived Suppressor Cells. J Immunol. 2020;204:3400-3415 pubmed publisher |
Azizov V, Dietel K, Steffen F, Dürholz K, Meidenbauer J, Lucas S, et al. Ethanol consumption inhibits TFH cell responses and the development of autoimmune arthritis. Nat Commun. 2020;11:1998 pubmed publisher |
Hewitson J, West K, James K, Rani G, Dey N, Romano A, et al. Malat1 Suppresses Immunity to Infection through Promoting Expression of Maf and IL-10 in Th Cells. J Immunol. 2020;204:2949-2960 pubmed publisher |
He H, Xu P, Zhang X, Liao M, Dong Q, Cong T, et al. Aging-induced IL27Ra signaling impairs hematopoietic stem cells. Blood. 2020;136:183-198 pubmed publisher |
Mayr L, Grabherr F, Schwärzler J, Reitmeier I, Sommer F, Gehmacher T, et al. Dietary lipids fuel GPX4-restricted enteritis resembling Crohn's disease. Nat Commun. 2020;11:1775 pubmed publisher |
Yang G, Song W, Postoak J, Chen J, Martinez J, Zhang J, et al. Autophagy-related protein PIK3C3/VPS34 controls T cell metabolism and function. Autophagy. 2021;17:1193-1204 pubmed publisher |
Francisco D, Wang Y, Conway M, Hurbon A, Dy A, Addison K, et al. Surfactant Protein-A Protects against IL-13-Induced Inflammation in Asthma. J Immunol. 2020;204:2829-2839 pubmed publisher |
Wang Z, Zhao M, Yin J, Liu L, Hu L, Huang Y, et al. E4BP4-mediated inhibition of T follicular helper cell differentiation is compromised in autoimmune diseases. J Clin Invest. 2020;130:3717-3733 pubmed publisher |
Basilico S, Wang X, Kennedy A, Tzelepis K, Giotopoulos G, Kinston S, et al. Dissecting the early steps of MLL induced leukaemogenic transformation using a mouse model of AML. Nat Commun. 2020;11:1407 pubmed publisher |
Chen J, Martindale J, Abdelmohsen K, Kumar G, FORTINA P, Gorospe M, et al. RNA-Binding Protein HuR Promotes Th17 Cell Differentiation and Can Be Targeted to Reduce Autoimmune Neuroinflammation. J Immunol. 2020;204:2076-2087 pubmed publisher |
Liu F, Wang X, Geng H, Bu H, Wang P, De Plaen I, et al. Interferon-γ inhibits sirtuin 6 gene expression in intestinal epithelial cells through a microRNA-92b-dependent mechanism. Am J Physiol Cell Physiol. 2020;318:C732-C739 pubmed publisher |
Wang X, Ni L, Wan S, Zhao X, Ding X, Dejean A, et al. Febrile Temperature Critically Controls the Differentiation and Pathogenicity of T Helper 17 Cells. Immunity. 2020;52:328-341.e5 pubmed publisher |
Roy D, Chen J, Mamane V, Ma E, Muhire B, Sheldon R, et al. Methionine Metabolism Shapes T Helper Cell Responses through Regulation of Epigenetic Reprogramming. Cell Metab. 2020;31:250-266.e9 pubmed publisher |
Oatley M, Bölükbaşı Ö, Svensson V, Shvartsman M, Ganter K, Zirngibl K, et al. Single-cell transcriptomics identifies CD44 as a marker and regulator of endothelial to haematopoietic transition. Nat Commun. 2020;11:586 pubmed publisher |
Song B, Lee J, Park Y, Kim I, Kim B, Shin K, et al. Differentiation of c-Kit+ CD24+ natural killer cells into myeloid cells in a GATA-2-dependent manner. FASEB J. 2020;34:4462-4481 pubmed publisher |
Gao Y, Deason K, Jain A, Irizarry Caro R, Dozmorov I, Coughlin L, et al. Transcriptional profiling identifies caspase-1 as a T cell-intrinsic regulator of Th17 differentiation. J Exp Med. 2020;217: pubmed publisher |
Kang L, Zhang X, Ji L, Kou T, Smith S, Zhao B, et al. The colonic macrophage transcription factor RBP-J orchestrates intestinal immunity against bacterial pathogens. J Exp Med. 2020;217: pubmed publisher |
Sidwell T, Liao Y, Garnham A, Vasanthakumar A, Gloury R, Blume J, et al. Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis. Nat Commun. 2020;11:252 pubmed publisher |
Chen C, Li B, Millman S, Chen C, Li X, Morris J, et al. Vitamin B6 Addiction in Acute Myeloid Leukemia. Cancer Cell. 2020;37:71-84.e7 pubmed publisher |
Vyas S, Hansda A, Kaplan M, Goswami R. Calcitriol Regulates the Differentiation of IL-9-Secreting Th9 Cells by Modulating the Transcription Factor PU.1. J Immunol. 2020;204:1201-1213 pubmed publisher |
Okuyama Y, Nagashima H, Ushio Fukai M, Croft M, Ishii N, So T. IQGAP1 restrains T-cell cosignaling mediated by OX40. FASEB J. 2020;34:540-554 pubmed publisher |
Oppezzo A, Bourseguin J, Renaud E, Pawlikowska P, Rosselli F. Microphthalmia transcription factor expression contributes to bone marrow failure in Fanconi anemia. J Clin Invest. 2020;130:1377-1391 pubmed publisher |
Lückel C, Picard F, Raifer H, Campos Carrascosa L, Guralnik A, Zhang Y, et al. IL-17+ CD8+ T cell suppression by dimethyl fumarate associates with clinical response in multiple sclerosis. Nat Commun. 2019;10:5722 pubmed publisher |
Huang C, Chiu S, Huang H, Cheng B, Pan H, Huang W, et al. A reporter mouse for non-invasive detection of toll-like receptor ligands induced acute phase responses. Sci Rep. 2019;9:19065 pubmed publisher |
Wang Y, Lu T, Sun G, Zheng Y, Yang S, Zhang H, et al. Targeting of apoptosis gene loci by reprogramming factors leads to selective eradication of leukemia cells. Nat Commun. 2019;10:5594 pubmed publisher |
Dietrich J, Ott L, Roth M, Witt J, Geerling G, Mertsch S, et al. MSC Transplantation Improves Lacrimal Gland Regeneration after Surgically Induced Dry Eye Disease in Mice. Sci Rep. 2019;9:18299 pubmed publisher |
Greenberg Z, Monlish D, Bartnett R, Yang Y, Shen G, Li W, et al. The Tetraspanin CD53 Regulates Early B Cell Development by Promoting IL-7R Signaling. J Immunol. 2020;204:58-67 pubmed publisher |
Xu W, Zhao X, Wang X, Feng H, Gou M, Jin W, et al. The Transcription Factor Tox2 Drives T Follicular Helper Cell Development via Regulating Chromatin Accessibility. Immunity. 2019;51:826-839.e5 pubmed publisher |
Xiong Z, Xia P, Zhu X, Geng J, Wang S, Ye B, et al. Glutamylation of deubiquitinase BAP1 controls self-renewal of hematopoietic stem cells and hematopoiesis. J Exp Med. 2020;217: pubmed publisher |
Labi V, Peng S, Klironomos F, Munschauer M, Kastelic N, Chakraborty T, et al. Context-specific regulation of cell survival by a miRNA-controlled BIM rheostat. Genes Dev. 2019;33:1673-1687 pubmed publisher |
Brown C, Gudjonson H, Pritykin Y, Deep D, Lavallée V, Mendoza A, et al. Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity. Cell. 2019;179:846-863.e24 pubmed publisher |
Yan D, Wang J, Sun H, Zamani A, Zhang H, Chen W, et al. TIPE2 specifies the functional polarization of myeloid-derived suppressor cells during tumorigenesis. J Exp Med. 2020;217: pubmed publisher |
Zhou W, Yui M, Williams B, Yun J, Wold B, Cai L, et al. Single-Cell Analysis Reveals Regulatory Gene Expression Dynamics Leading to Lineage Commitment in Early T Cell Development. Cell Syst. 2019;9:321-337.e9 pubmed publisher |
I T, Sumita Y, Yoshida T, Honma R, Iwatake M, Raudales J, et al. Anti-inflammatory and vasculogenic conditioning of peripheral blood mononuclear cells reinforces their therapeutic potential for radiation-injured salivary glands. Stem Cell Res Ther. 2019;10:304 pubmed publisher |
Sun X, Cui Y, Feng H, Liu H, Liu X. TGF-β signaling controls Foxp3 methylation and T reg cell differentiation by modulating Uhrf1 activity. J Exp Med. 2019;216:2819-2837 pubmed publisher |
Albright A, Kabat J, Li M, Raso F, Reboldi A, Muppidi J. TGFβ signaling in germinal center B cells promotes the transition from light zone to dark zone. J Exp Med. 2019;216:2531-2545 pubmed publisher |
Mondragon L, Mhaidly R, De Donatis G, Tosolini M, Dao P, Martin A, et al. GAPDH Overexpression in the T Cell Lineage Promotes Angioimmunoblastic T Cell Lymphoma through an NF-κB-Dependent Mechanism. Cancer Cell. 2019;36:268-287.e10 pubmed publisher |
Schüler F, Afreen S, Manzl C, Hacker G, Erlacher M, Villunger A. Checkpoint kinase 1 is essential for fetal and adult hematopoiesis. EMBO Rep. 2019;20:e47026 pubmed publisher |
Hagenstein J, Melderis S, Nosko A, Warkotsch M, Richter J, Ramcke T, et al. A Novel Role for IL-6 Receptor Classic Signaling: Induction of RORγt+Foxp3+ Tregs with Enhanced Suppressive Capacity. J Am Soc Nephrol. 2019;30:1439-1453 pubmed publisher |
Tyrkalska S, Pérez Oliva A, Rodríguez Ruiz L, Martínez Morcillo F, Alcaraz Pérez F, Martínez Navarro F, et al. Inflammasome Regulates Hematopoiesis through Cleavage of the Master Erythroid Transcription Factor GATA1. Immunity. 2019;: pubmed publisher |
Zhou J, Huang S, Wang Z, Huang J, Xu L, Tang X, et al. Targeting EZH2 histone methyltransferase activity alleviates experimental intestinal inflammation. Nat Commun. 2019;10:2427 pubmed publisher |
Nagatake T, Hirata S, Koga T, Kuroda E, Kobari S, Suzuki H, et al. BLT1 mediates commensal bacteria-dependent innate immune signals to enhance antigen-specific intestinal IgA responses. Mucosal Immunol. 2019;: pubmed publisher |
Kaushik D, Bhattacharya A, Mirzaei R, Rawji K, Ahn Y, Rho J, et al. Enhanced glycolytic metabolism supports transmigration of brain-infiltrating macrophages in multiple sclerosis. J Clin Invest. 2019;129:3277-3292 pubmed publisher |
Grassmann S, Pachmayr L, Leube J, Mihatsch L, Andrae I, Flommersfeld S, et al. Distinct Surface Expression of Activating Receptor Ly49H Drives Differential Expansion of NK Cell Clones upon Murine Cytomegalovirus Infection. Immunity. 2019;: pubmed publisher |
Townsend L, Medak K, Peppler W, Meers G, Rector R, Leblanc P, et al. High Saturated Fat Diet-Induced Obesity Causes Hepatic Interleukin-6 Resistance via Endoplasmic Reticulum Stress. J Lipid Res. 2019;: pubmed publisher |
Komuczki J, Tuzlak S, Friebel E, Hartwig T, Spath S, Rosenstiel P, et al. Fate-Mapping of GM-CSF Expression Identifies a Discrete Subset of Inflammation-Driving T Helper Cells Regulated by Cytokines IL-23 and IL-1β. Immunity. 2019;: pubmed publisher |
Tanaka H, Arima Y, Kamimura D, Tanaka Y, Takahashi N, Uehata T, et al. Phosphorylation-dependent Regnase-1 release from endoplasmic reticulum is critical in IL-17 response. J Exp Med. 2019;216:1431-1449 pubmed publisher |
Myers D, Norlin E, Vercoulen Y, Roose J. Active Tonic mTORC1 Signals Shape Baseline Translation in Naive T Cells. Cell Rep. 2019;27:1858-1874.e6 pubmed publisher |
Chu Y, Chen Y, Li M, Shi D, Wang B, Lian Y, et al. Six1 regulates leukemia stem cell maintenance in acute myeloid leukemia. Cancer Sci. 2019;110:2200-2210 pubmed publisher |
Sala D, Cunningham T, Stec M, Etxaniz U, Nicoletti C, Dall Agnese A, et al. The Stat3-Fam3a axis promotes muscle stem cell myogenic lineage progression by inducing mitochondrial respiration. Nat Commun. 2019;10:1796 pubmed publisher |
Yue S, Zheng X, Zheng Y. Cell-type-specific role of lamin-B1 in thymus development and its inflammation-driven reduction in thymus aging. Aging Cell. 2019;18:e12952 pubmed publisher |
Mack E, Stein S, Rome K, Xu L, Wertheim G, Melo R, et al. Trib1 regulates eosinophil lineage commitment and identity by restraining the neutrophil program. Blood. 2019;: pubmed publisher |
Castelli A, Susani L, Menale C, Muggeo S, Caldana E, Strina D, et al. Chromosome Transplantation: Correction of the Chronic Granulomatous Disease Defect in Mouse Induced Pluripotent Stem Cells. Stem Cells. 2019;37:876-887 pubmed publisher |
Lin C, Wang Z, Duque Afonso J, Wong S, Demeter J, Loktev A, et al. Oligomeric self-association contributes to E2A-PBX1-mediated oncogenesis. Sci Rep. 2019;9:4915 pubmed publisher |
Basheer F, Giotopoulos G, Meduri E, Yun H, Mazan M, Sasca D, et al. Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AML. J Exp Med. 2019;216:966-981 pubmed publisher |
Li H, Natarajan A, Ezike J, Barrasa M, Le Y, Feder Z, et al. Rate of Progression through a Continuum of Transit-Amplifying Progenitor Cell States Regulates Blood Cell Production. Dev Cell. 2019;49:118-129.e7 pubmed publisher |
Luu M, Pautz S, Kohl V, Singh R, Romero R, Lucas S, et al. The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes. Nat Commun. 2019;10:760 pubmed publisher |
Yang J, Yang X, Yang J, Li M. Baicalin ameliorates lupus autoimmunity by inhibiting differentiation of Tfh cells and inducing expansion of Tfr cells. Cell Death Dis. 2019;10:140 pubmed publisher |
Wang Y, Richter L, Becker M, Amador C, Hyde R. IL1RL1 is dynamically expressed on Cbfb-MYH11+ leukemia stem cells and promotes cell survival. Sci Rep. 2019;9:1729 pubmed publisher |
Li Y, Hu Q, Li C, Liang K, Xiang Y, Hsiao H, et al. PTEN-induced partial epithelial-mesenchymal transition drives diabetic kidney disease. J Clin Invest. 2019;129:1129-1151 pubmed publisher |
Denton A, Innocentin S, Carr E, Bradford B, Lafouresse F, Mabbott N, et al. Type I interferon induces CXCL13 to support ectopic germinal center formation. J Exp Med. 2019;216:621-637 pubmed publisher |
Frossi B, Antoniali G, Yu K, Akhtar N, Kaplan M, Kelley M, et al. Endonuclease and redox activities of human apurinic/apyrimidinic endonuclease 1 have distinctive and essential functions in IgA class switch recombination. J Biol Chem. 2019;294:5198-5207 pubmed publisher |
Zhang Y, Hu N, Dong F. Gfi1-Mediated Repression of c-Fos, Egr-1 and Egr-2, and Inhibition of ERK1/2 Signaling Contribute to the Role of Gfi1 in Granulopoiesis. Sci Rep. 2019;9:737 pubmed publisher |
Luo H, Mu W, Karki R, Chiang H, Mohrin M, Shin J, et al. Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging. Cell Rep. 2019;26:945-954.e4 pubmed publisher |
Minshawi F, White M, Muller W, Humphreys N, Jackson D, Campbell B, et al. Human TNF-Luc reporter mouse: A new model to quantify inflammatory responses. Sci Rep. 2019;9:193 pubmed publisher |
Weckbach L, Grabmaier U, Uhl A, Gess S, Boehm F, Zehrer A, et al. Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis. J Exp Med. 2019;216:350-368 pubmed publisher |
Muccioli M, Nandigam H, Loftus T, Singh M, Venkatesh A, Wright J, et al. Modulation of double-stranded RNA pattern recognition receptor signaling in ovarian cancer cells promotes inflammatory queues. Oncotarget. 2018;9:36666-36683 pubmed publisher |
Rojas O, Pröbstel A, Porfilio E, Wang A, Charabati M, Sun T, et al. Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10. Cell. 2019;176:610-624.e18 pubmed publisher |
Tzelepis K, De Braekeleer E, Aspris D, Barbieri I, Vijayabaskar M, Liu W, et al. SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4. Nat Commun. 2018;9:5378 pubmed publisher |
Izumi T, Imai J, Yamamoto J, Kawana Y, Endo A, Sugawara H, et al. Vagus-macrophage-hepatocyte link promotes post-injury liver regeneration and whole-body survival through hepatic FoxM1 activation. Nat Commun. 2018;9:5300 pubmed publisher |
Protopsaltis N, Liang W, Nudleman E, Ferrara N. Interleukin-22 promotes tumor angiogenesis. Angiogenesis. 2019;22:311-323 pubmed publisher |
Chaudhury S, O Connor C, Cañete A, Bittencourt Silvestre J, Sarrou E, Prendergast Á, et al. Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias. Nat Commun. 2018;9:5280 pubmed publisher |
Chen Z, Amro E, Becker F, Holzer M, Rasa S, Njeru S, et al. Cohesin-mediated NF-κB signaling limits hematopoietic stem cell self-renewal in aging and inflammation. J Exp Med. 2019;216:152-175 pubmed publisher |
Calcinotto A, Brevi A, Chesi M, Ferrarese R, Garcia Perez L, Grioni M, et al. Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression. Nat Commun. 2018;9:4832 pubmed publisher |
Grohmann M, Wiede F, Dodd G, Gurzov E, Ooi G, Butt T, et al. Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC. Cell. 2018;175:1289-1306.e20 pubmed publisher |
Koh B, Abdul Qayum A, Srivastava R, Fu Y, Ulrich B, Janga S, et al. A conserved enhancer regulates Il9 expression in multiple lineages. Nat Commun. 2018;9:4803 pubmed publisher |
Lim T, Su I. Talin1 Methylation Is Required for Neutrophil Infiltration and Lipopolysaccharide-Induced Lethality. J Immunol. 2018;201:3651-3661 pubmed publisher |
Yin W, Song Y, Chang X. Single-cell RNA-Seq analysis identifies a noncoding interleukin 4 (IL-4) RNA that post-transcriptionally up-regulates IL-4 production in T helper cells. J Biol Chem. 2019;294:290-298 pubmed publisher |
Abdul Aziz A, Sun Y, Hellmich C, Marlein C, Mistry J, Forde E, et al. Acute myeloid leukemia induces pro-tumoral p16INK4a driven senescence in the bone marrow microenvironment. Blood. 2018;: pubmed publisher |
Fatkhullina A, Peshkova I, Dzutsev A, Aghayev T, McCulloch J, Thovarai V, et al. An Interleukin-23-Interleukin-22 Axis Regulates Intestinal Microbial Homeostasis to Protect from Diet-Induced Atherosclerosis. Immunity. 2018;49:943-957.e9 pubmed publisher |
Mulati K, Hamanishi J, Matsumura N, Chamoto K, Mise N, Abiko K, et al. VISTA expressed in tumour cells regulates T cell function. Br J Cancer. 2019;120:115-127 pubmed publisher |
Singh A, Khare P, Obaid A, Conlon K, Basrur V, Depinho R, et al. SUMOylation of ROR-γt inhibits IL-17 expression and inflammation via HDAC2. Nat Commun. 2018;9:4515 pubmed publisher |
Philipp D, Suhr L, Wahlers T, Choi Y, Paunel Görgülü A. Preconditioning of bone marrow-derived mesenchymal stem cells highly strengthens their potential to promote IL-6-dependent M2b polarization. Stem Cell Res Ther. 2018;9:286 pubmed publisher |
Su H, Hu J, Huang L, Yang Y, Thenoz M, Kuchmiy A, et al. SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival. Nat Commun. 2018;9:4281 pubmed publisher |
Boulais P, Mizoguchi T, Zimmerman S, Nakahara F, Vivié J, Mar J, et al. The Majority of CD45- Ter119- CD31- Bone Marrow Cell Fraction Is of Hematopoietic Origin and Contains Erythroid and Lymphoid Progenitors. Immunity. 2018;49:627-639.e6 pubmed publisher |
Das P, Veazey K, Van H, Kaushik S, Lin K, Lu Y, et al. Histone methylation regulator PTIP is required to maintain normal and leukemic bone marrow niches. Proc Natl Acad Sci U S A. 2018;115:E10137-E10146 pubmed publisher |
Upadhaya S, Sawai C, Papalexi E, Rashidfarrokhi A, Jang G, Chattopadhyay P, et al. Kinetics of adult hematopoietic stem cell differentiation in vivo. J Exp Med. 2018;215:2815-2832 pubmed publisher |
Giambra V, Gusscott S, Gracias D, Song R, Lam S, Panelli P, et al. Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity. Cell Stem Cell. 2018;23:714-726.e7 pubmed publisher |
Luu M, Weigand K, Wedi F, Breidenbend C, Leister H, Pautz S, et al. Regulation of the effector function of CD8+ T cells by gut microbiota-derived metabolite butyrate. Sci Rep. 2018;8:14430 pubmed publisher |
Yano H, Sakai M, Matsukawa T, Yagi T, Naganuma T, Mitsushima M, et al. PHD3 regulates glucose metabolism by suppressing stress-induced signalling and optimising gluconeogenesis and insulin signalling in hepatocytes. Sci Rep. 2018;8:14290 pubmed publisher |
Xu Y, Sun Y, Shen H, Dai Y, Liu H, Li R, et al. Regulation of the terminal maturation of iNKT cells by mediator complex subunit 23. Nat Commun. 2018;9:3875 pubmed publisher |
Chen S, Yun F, Yao Y, Cao M, Zhang Y, Wang J, et al. USP38 critically promotes asthmatic pathogenesis by stabilizing JunB protein. J Exp Med. 2018;215:2850-2867 pubmed publisher |
Lian G, Gnanaprakasam J, Wang T, Wu R, Chen X, Liu L, et al. Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation. elife. 2018;7: pubmed publisher |
Kauts M, De Leo B, Rodríguez Seoane C, Ronn R, Glykofrydis F, Maglitto A, et al. Rapid Mast Cell Generation from Gata2 Reporter Pluripotent Stem Cells. Stem Cell Reports. 2018;11:1009-1020 pubmed publisher |
Lv Q, Shi C, Qiao S, Cao N, Guan C, Dai Y, et al. Alpinetin exerts anti-colitis efficacy by activating AhR, regulating miR-302/DNMT-1/CREB signals, and therefore promoting Treg differentiation. Cell Death Dis. 2018;9:890 pubmed publisher |
Minzel W, Venkatachalam A, Fink A, Hung E, Brachya G, Burstain I, et al. Small Molecules Co-targeting CKIα and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models. Cell. 2018;175:171-185.e25 pubmed publisher |
Zhang H, Xu Z, Lin H, Li M, Xia T, Cui K, et al. TRIM27 mediates STAT3 activation at retromer-positive structures to promote colitis and colitis-associated carcinogenesis. Nat Commun. 2018;9:3441 pubmed publisher |
Fuseini H, Yung J, Cephus J, Zhang J, Goleniewska K, Polosukhin V, et al. Testosterone Decreases House Dust Mite-Induced Type 2 and IL-17A-Mediated Airway Inflammation. J Immunol. 2018;201:1843-1854 pubmed publisher |
Vanden Bempt M, Demeyer S, Broux M, De Bie J, Bornschein S, Mentens N, et al. Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia. Cancer Cell. 2018;34:271-285.e7 pubmed publisher |
Deason K, Troutman T, Jain A, Challa D, Mandraju R, Brewer T, et al. BCAP links IL-1R to the PI3K-mTOR pathway and regulates pathogenic Th17 cell differentiation. J Exp Med. 2018;215:2413-2428 pubmed publisher |
Rodrigues C, Serrano E, Patrício M, Val M, Albuquerque P, Fonseca J, et al. Stroma-derived IL-6, G-CSF and Activin-A mediated dedifferentiation of lung carcinoma cells into cancer stem cells. Sci Rep. 2018;8:11573 pubmed publisher |
Zehrer A, Pick R, Salvermoser M, Boda A, Miller M, Stark K, et al. A Fundamental Role of Myh9 for Neutrophil Migration in Innate Immunity. J Immunol. 2018;201:1748-1764 pubmed publisher |
Hartmann J, Bräuer Hartmann D, Kardosova M, Wurm A, Wilke F, Schödel C, et al. MicroRNA-143 targets ERK5 in granulopoiesis and predicts outcome of patients with acute myeloid leukemia. Cell Death Dis. 2018;9:814 pubmed publisher |
Bian J, Liu R, Fan T, Liao L, Wang S, Geng W, et al. miR-340 Alleviates Psoriasis in Mice through Direct Targeting of IL-17A. J Immunol. 2018;201:1412-1420 pubmed publisher |
Kosicki M, Tomberg K, Bradley A. Repair of double-strand breaks induced by CRISPR-Cas9 leads to large deletions and complex rearrangements. Nat Biotechnol. 2018;36:765-771 pubmed publisher |
Sharma S, Cermakova K, De Rijck J, Demeulemeester J, Fabry M, El Ashkar S, et al. Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation. Proc Natl Acad Sci U S A. 2018;115:E7053-E7062 pubmed publisher |
Woo J, Srikanth S, Kim K, Elsaesser H, Lu J, Pellegrini M, et al. CRACR2A-Mediated TCR Signaling Promotes Local Effector Th1 and Th17 Responses. J Immunol. 2018;201:1174-1185 pubmed publisher |
Pulikkan J, Hegde M, Ahmad H, Belaghzal H, Illendula A, Yu J, et al. CBFβ-SMMHC Inhibition Triggers Apoptosis by Disrupting MYC Chromatin Dynamics in Acute Myeloid Leukemia. Cell. 2018;174:172-186.e21 pubmed publisher |
Tanaka S, Jiang Y, Martinez G, Tanaka K, Yan X, Kurosaki T, et al. Trim33 mediates the proinflammatory function of Th17 cells. J Exp Med. 2018;215:1853-1868 pubmed publisher |
Do N, Willenborg S, Eckes B, Jüngst C, Sengle G, Zaucke F, et al. Myeloid Cell-Restricted STAT3 Signaling Controls a Cell-Autonomous Antifibrotic Repair Program. J Immunol. 2018;201:663-674 pubmed publisher |
Hashiguchi Y, Yabe R, Chung S, Murayama M, Yoshida K, Matsuo K, et al. IL-36α from Skin-Resident Cells Plays an Important Role in the Pathogenesis of Imiquimod-Induced Psoriasiform Dermatitis by Forming a Local Autoamplification Loop. J Immunol. 2018;201:167-182 pubmed publisher |
Sinclair L, Neyens D, Ramsay G, Taylor P, Cantrell D. Single cell analysis of kynurenine and System L amino acid transport in T cells. Nat Commun. 2018;9:1981 pubmed publisher |
Yu F, Sharma S, Jankovic D, Gurram R, Su P, Hu G, et al. The transcription factor Bhlhe40 is a switch of inflammatory versus antiinflammatory Th1 cell fate determination. J Exp Med. 2018;215:1813-1821 pubmed publisher |
Rothberg J, Maganti H, Jrade H, Porter C, Palidwor G, Cafariello C, et al. Mtf2-PRC2 control of canonical Wnt signaling is required for definitive erythropoiesis. Cell Discov. 2018;4:21 pubmed publisher |
Vian L, Pekowska A, Rao S, Kieffer Kwon K, Jung S, Baranello L, et al. The Energetics and Physiological Impact of Cohesin Extrusion. Cell. 2018;173:1165-1178.e20 pubmed publisher |
Numata A, Kwok H, Kawasaki A, Li J, Zhou Q, Kerry J, et al. The basic helix-loop-helix transcription factor SHARP1 is an oncogenic driver in MLL-AF6 acute myelogenous leukemia. Nat Commun. 2018;9:1622 pubmed publisher |
Tu E, Chia C, Chen W, Zhang D, Park S, Jin W, et al. T Cell Receptor-Regulated TGF-β Type I Receptor Expression Determines T Cell Quiescence and Activation. Immunity. 2018;48:745-759.e6 pubmed publisher |
Jiang Y, Liu Y, Lu H, Sun S, Jin W, Wang X, et al. Epigenetic activation during T helper 17 cell differentiation is mediated by Tripartite motif containing 28. Nat Commun. 2018;9:1424 pubmed publisher |
Barbieri D, Elvira Matelot E, Pelinski Y, Genève L, de Laval B, Yogarajah G, et al. Thrombopoietin protects hematopoietic stem cells from retrotransposon-mediated damage by promoting an antiviral response. J Exp Med. 2018;215:1463-1480 pubmed publisher |
Zhang Y, Xia F, Liu X, Yu Z, Xie L, Liu L, et al. JAM3 maintains leukemia-initiating cell self-renewal through LRP5/AKT/?-catenin/CCND1 signaling. J Clin Invest. 2018;128:1737-1751 pubmed publisher |
Gao Y, Wang T, Li Y, Zhang Y, Yang R. Lnc-chop Promotes Immunosuppressive Function of Myeloid-Derived Suppressor Cells in Tumor and Inflammatory Environments. J Immunol. 2018;200:2603-2614 pubmed publisher |
Lei Z, Duan H, Zhao T, Zhang Y, Li G, Meng J, et al. PARK2 inhibits osteosarcoma cell growth through the JAK2/STAT3/VEGF signaling pathway. Cell Death Dis. 2018;9:375 pubmed publisher |
Maes T, Mascaró C, Tirapu I, Estiarte A, Ciceri F, Lunardi S, et al. ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia. Cancer Cell. 2018;33:495-511.e12 pubmed publisher |
Tusi B, Wolock S, Weinreb C, Hwang Y, Hidalgo D, Zilionis R, et al. Population snapshots predict early haematopoietic and erythroid hierarchies. Nature. 2018;555:54-60 pubmed publisher |
Gallipoli P, Giotopoulos G, Tzelepis K, Costa A, Vohra S, Medina Pérez P, et al. Glutaminolysis is a metabolic dependency in FLT3ITD acute myeloid leukemia unmasked by FLT3 tyrosine kinase inhibition. Blood. 2018;: pubmed publisher |
Tong W, Zhang C, Hong T, Liu D, Wang C, Li J, et al. Silibinin alleviates inflammation and induces apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes and has a therapeutic effect on arthritis in rats. Sci Rep. 2018;8:3241 pubmed publisher |
Tsukasaki M, Komatsu N, Nagashima K, Nitta T, Pluemsakunthai W, Shukunami C, et al. Host defense against oral microbiota by bone-damaging T cells. Nat Commun. 2018;9:701 pubmed publisher |
Massara M, Bonavita O, Savino B, Caronni N, Mollica Poeta V, Sironi M, et al. ACKR2 in hematopoietic precursors as a checkpoint of neutrophil release and anti-metastatic activity. Nat Commun. 2018;9:676 pubmed publisher |
Booth C, Barkas N, Neo W, Boukarabila H, Soilleux E, Giotopoulos G, et al. Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors. Cancer Cell. 2018;33:274-291.e8 pubmed publisher |
Cortes J, Ambesi Impiombato A, Couronné L, Quinn S, Kim C, da Silva Almeida A, et al. RHOA G17V Induces T Follicular Helper Cell Specification and Promotes Lymphomagenesis. Cancer Cell. 2018;33:259-273.e7 pubmed publisher |
Halasi M, Hitchinson B, Shah B, Váraljai R, Khan I, Benevolenskaya E, et al. Honokiol is a FOXM1 antagonist. Cell Death Dis. 2018;9:84 pubmed publisher |
Meng X, Grötsch B, Luo Y, Knaup K, Wiesener M, Chen X, et al. Hypoxia-inducible factor-1α is a critical transcription factor for IL-10-producing B cells in autoimmune disease. Nat Commun. 2018;9:251 pubmed publisher |
Castellani L, Peppler W, Miotto P, Bush N, Wright D. Exercise Protects Against Olanzapine-Induced Hyperglycemia in Male C57BL/6J Mice. Sci Rep. 2018;8:772 pubmed publisher |
Yan J, Tie G, Wang S, Tutto A, DeMarco N, Khair L, et al. Diabetes impairs wound healing by Dnmt1-dependent dysregulation of hematopoietic stem cells differentiation towards macrophages. Nat Commun. 2018;9:33 pubmed publisher |
Sen S, Wang F, Zhang J, He Z, Ma J, Gwack Y, et al. SRC1 promotes Th17 differentiation by overriding Foxp3 suppression to stimulate ROR?t activity in a PKC-?-dependent manner. Proc Natl Acad Sci U S A. 2018;115:E458-E467 pubmed publisher |
Mumau M, Vanderbeck A, Lynch E, Golec S, Emerson S, Punt J. Identification of a Multipotent Progenitor Population in the Spleen That Is Regulated by NR4A1. J Immunol. 2018;200:1078-1087 pubmed publisher |
Kauts M, Rodríguez Seoane C, Kaimakis P, Mendes S, Cortés Lavaud X, Hill U, et al. In Vitro Differentiation of Gata2 and Ly6a Reporter Embryonic Stem Cells Corresponds to In Vivo Waves of Hematopoietic Cell Generation. Stem Cell Reports. 2018;10:151-165 pubmed publisher |
Fu B, Zhou Y, Ni X, Tong X, Xu X, Dong Z, et al. Natural Killer Cells Promote Fetal Development through the Secretion of Growth-Promoting Factors. Immunity. 2017;47:1100-1113.e6 pubmed publisher |
Kleppe M, Koche R, Zou L, van Galen P, Hill C, Dong L, et al. Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms. Cancer Cell. 2018;33:29-43.e7 pubmed publisher |
Essig K, Hu D, Guimaraes J, Alterauge D, Edelmann S, Raj T, et al. Roquin Suppresses the PI3K-mTOR Signaling Pathway to Inhibit T Helper Cell Differentiation and Conversion of Treg to Tfr Cells. Immunity. 2017;47:1067-1082.e12 pubmed publisher |
Yamazaki S, Tanaka Y, Araki H, Kohda A, Sanematsu F, Arasaki T, et al. The AP-1 transcription factor JunB is required for Th17 cell differentiation. Sci Rep. 2017;7:17402 pubmed publisher |
Okuma A, Hanyu A, Watanabe S, Hara E. p16Ink4a and p21Cip1/Waf1 promote tumour growth by enhancing myeloid-derived suppressor cells chemotaxis. Nat Commun. 2017;8:2050 pubmed publisher |
Wu J, Zhang H, Shi X, Xiao X, Fan Y, Minze L, et al. Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic CD4+ T Cell Dysfunction. Immunity. 2017;47:1114-1128.e6 pubmed publisher |
Romagnani A, Vettore V, Rezzonico Jost T, Hampe S, Rottoli E, Nadolni W, et al. TRPM7 kinase activity is essential for T cell colonization and alloreactivity in the gut. Nat Commun. 2017;8:1917 pubmed publisher |
Barbieri I, Tzelepis K, Pandolfini L, Shi J, Millán Zambrano G, Robson S, et al. Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control. Nature. 2017;552:126-131 pubmed publisher |
Hawila E, Razon H, Wildbaum G, Blattner C, Sapir Y, Shaked Y, et al. CCR5 Directs the Mobilization of CD11b+Gr1+Ly6Clow Polymorphonuclear Myeloid Cells from the Bone Marrow to the Blood to Support Tumor Development. Cell Rep. 2017;21:2212-2222 pubmed publisher |
Pitre A, Ge Y, Lin W, Wang Y, Fukuda Y, Temirov J, et al. An unexpected protein interaction promotes drug resistance in leukemia. Nat Commun. 2017;8:1547 pubmed publisher |
Lee Y, Lee M, Kim H, Won H, Kim C. Non-thermal atmospheric plasma ameliorates imiquimod-induced psoriasis-like skin inflammation in mice through inhibition of immune responses and up-regulation of PD-L1 expression. Sci Rep. 2017;7:15564 pubmed publisher |
Kleinschmidt D, Giannou A, McGee H, Kempski J, Steglich B, Huber F, et al. A Protective Function of IL-22BP in Ischemia Reperfusion and Acetaminophen-Induced Liver Injury. J Immunol. 2017;199:4078-4090 pubmed publisher |
El Ashkar S, Schwaller J, Pieters T, Goossens S, Demeulemeester J, Christ F, et al. LEDGF/p75 is dispensable for hematopoiesis but essential for MLL-rearranged leukemogenesis. Blood. 2017;: pubmed publisher |
Sarkar S, Malovic E, Harishchandra D, Ghaisas S, Panicker N, Charli A, et al. Mitochondrial impairment in microglia amplifies NLRP3 inflammasome proinflammatory signaling in cell culture and animal models of Parkinson's disease. NPJ Parkinsons Dis. 2017;3:30 pubmed publisher |
Moretti J, Roy S, Bozec D, Martinez J, Chapman J, Ueberheide B, et al. STING Senses Microbial Viability to Orchestrate Stress-Mediated Autophagy of the Endoplasmic Reticulum. Cell. 2017;171:809-823.e13 pubmed publisher |
Ayaub E, Dubey A, Imani J, Botelho F, Kolb M, Richards C, et al. Overexpression of OSM and IL-6 impacts the polarization of pro-fibrotic macrophages and the development of bleomycin-induced lung fibrosis. Sci Rep. 2017;7:13281 pubmed publisher |
Pike K, Hatzihristidis T, Bussières Marmen S, Robert F, Desai N, Miranda Saavedra D, et al. TC-PTP regulates the IL-7 transcriptional response during murine early T cell development. Sci Rep. 2017;7:13275 pubmed publisher |
Kottke T, Evgin L, Shim K, Rommelfanger D, Boisgerault N, Zaidi S, et al. Subversion of NK-cell and TNF? Immune Surveillance Drives Tumor Recurrence. Cancer Immunol Res. 2017;5:1029-1045 pubmed publisher |
Lee S, Kivimäe S, Szoka F. Clodronate Improves Survival of Transplanted Hoxb8 Myeloid Progenitors with Constitutively Active GMCSFR in Immunocompetent Mice. Mol Ther Methods Clin Dev. 2017;7:60-73 pubmed publisher |
Stanulovic V, Cauchy P, Assi S, Hoogenkamp M. LMO2 is required for TAL1 DNA binding activity and initiation of definitive haematopoiesis at the haemangioblast stage. Nucleic Acids Res. 2017;45:9874-9888 pubmed publisher |
Stubbs M, Krivtsov A. Murine Retrovirally-Transduced Bone Marrow Engraftment Models of MLL-Fusion-Driven Acute Myelogenous Leukemias (AML). Curr Protoc Pharmacol. 2017;78:14.42.1-14.42.19 pubmed publisher |
Sun S, Wang R, Song J, Guan M, Li N, Zhang X, et al. Blocking gp130 signaling suppresses autotaxin expression in adipocytes and improves insulin sensitivity in diet-induced obesity. J Lipid Res. 2017;58:2102-2113 pubmed publisher |
Li B, Wang X, Choi I, Wang Y, Liu S, Pham A, et al. miR-146a modulates autoreactive Th17 cell differentiation and regulates organ-specific autoimmunity. J Clin Invest. 2017;127:3702-3716 pubmed publisher |
Gao X, Lee H, Li W, Platt R, Barrasa M, Ma Q, et al. Thyroid hormone receptor beta and NCOA4 regulate terminal erythrocyte differentiation. Proc Natl Acad Sci U S A. 2017;114:10107-10112 pubmed publisher |
Simeonov D, Gowen B, Boontanrart M, Roth T, Gagnon J, Mumbach M, et al. Discovery of stimulation-responsive immune enhancers with CRISPR activation. Nature. 2017;549:111-115 pubmed publisher |
Dovey O, Cooper J, Mupo A, Grove C, Lynn C, Conte N, et al. Molecular synergy underlies the co-occurrence patterns and phenotype of NPM1-mutant acute myeloid leukemia. Blood. 2017;130:1911-1922 pubmed publisher |
Ranjan S, Goihl A, Kohli S, Gadi I, Pierau M, Shahzad K, et al. Activated protein C protects from GvHD via PAR2/PAR3 signalling in regulatory T-cells. Nat Commun. 2017;8:311 pubmed publisher |
Cimmino L, Dolgalev I, Wang Y, Yoshimi A, Martin G, Wang J, et al. Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression. Cell. 2017;170:1079-1095.e20 pubmed publisher |
Foreman H, Armstrong J, Santana A, Krug L, Reich N. The replication and transcription activator of murine gammaherpesvirus 68 cooperatively enhances cytokine-activated, STAT3-mediated gene expression. J Biol Chem. 2017;292:16257-16266 pubmed publisher |
Wiede F, Dudakov J, Lu K, Dodd G, Butt T, Godfrey D, et al. PTPN2 regulates T cell lineage commitment and αβ versus γδ specification. J Exp Med. 2017;214:2733-2758 pubmed publisher |
Gu Y, Zhang J, Ma X, Kim B, Wang H, Li J, et al. Stabilization of the c-Myc Protein by CAMKII? Promotes T Cell Lymphoma. Cancer Cell. 2017;32:115-128.e7 pubmed publisher |
Peraki I, Palis J, Mavrothalassitis G. The Ets2 Repressor Factor (Erf) Is Required for Effective Primitive and Definitive Hematopoiesis. Mol Cell Biol. 2017;37: pubmed publisher |
Chen J, Martindale J, Cramer C, Gorospe M, Atasoy U, Drew P, et al. The RNA-binding protein HuR contributes to neuroinflammation by promoting C-C chemokine receptor 6 (CCR6) expression on Th17 cells. J Biol Chem. 2017;292:14532-14543 pubmed publisher |
Ye J, Wang Y, Liu X, Li L, Opejin A, Hsueh E, et al. TLR7 Signaling Regulates Th17 Cells and Autoimmunity: Novel Potential for Autoimmune Therapy. J Immunol. 2017;199:941-954 pubmed publisher |
Ukah T, Cattin Roy A, Chen W, Miller M, Barik S, Zaghouani H. On the Role IL-4/IL-13 Heteroreceptor Plays in Regulation of Type 1 Diabetes. J Immunol. 2017;199:894-902 pubmed publisher |
Tsai P, Zhang B, He W, Zha J, Odenwald M, Singh G, et al. IL-22 Upregulates Epithelial Claudin-2 to Drive Diarrhea and Enteric Pathogen Clearance. Cell Host Microbe. 2017;21:671-681.e4 pubmed publisher |
Chen Y, Anastassiadis K, Kranz A, Stewart A, Arndt K, Waskow C, et al. MLL2, Not MLL1, Plays a Major Role in Sustaining MLL-Rearranged Acute Myeloid Leukemia. Cancer Cell. 2017;31:755-770.e6 pubmed publisher |
Montoya M, Maul J, Singh P, Pua H, Dahlström F, Wu N, et al. A Distinct Inhibitory Function for miR-18a in Th17 Cell Differentiation. J Immunol. 2017;199:559-569 pubmed publisher |
Tarasenko T, Pacheco S, Koenig M, Gomez Rodriguez J, Kapnick S, Diaz F, et al. Cytochrome c Oxidase Activity Is a Metabolic Checkpoint that Regulates Cell Fate Decisions During T Cell Activation and Differentiation. Cell Metab. 2017;25:1254-1268.e7 pubmed publisher |
Jeffery V, Goldson A, Dainty J, Chieppa M, Sobolewski A. IL-6 Signaling Regulates Small Intestinal Crypt Homeostasis. J Immunol. 2017;199:304-311 pubmed publisher |
Yang Q, Qiu H, Xie H, Qi Y, Cha H, Qu J, et al. A Schistosoma japonicum Infection Promotes the Expansion of Myeloid-Derived Suppressor Cells by Activating the JAK/STAT3 Pathway. J Immunol. 2017;198:4716-4727 pubmed publisher |
Olson M, Ulrich B, Hummel S, Khan I, Meuris B, Cherukuri Y, et al. Paracrine IL-2 Is Required for Optimal Type 2 Effector Cytokine Production. J Immunol. 2017;198:4352-4359 pubmed publisher |
Poh A, Love C, Masson F, Preaudet A, Tsui C, Whitehead L, et al. Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer Progression. Cancer Cell. 2017;31:563-575.e5 pubmed publisher |
Man N, Tan Y, Sun X, Liu F, Cheng G, Greenblatt S, et al. Caspase-3 controls AML1-ETO-driven leukemogenesis via autophagy modulation in a ULK1-dependent manner. Blood. 2017;129:2782-2792 pubmed publisher |
Schweighoffer E, Nys J, Vanes L, Smithers N, Tybulewicz V. TLR4 signals in B lymphocytes are transduced via the B cell antigen receptor and SYK. J Exp Med. 2017;214:1269-1280 pubmed publisher |
Vaeth M, Yang J, Yamashita M, Zee I, Eckstein M, Knosp C, et al. ORAI2 modulates store-operated calcium entry and T cell-mediated immunity. Nat Commun. 2017;8:14714 pubmed publisher |
Ohlund D, Handly Santana A, Biffi G, Elyada E, Almeida A, Ponz Sarvisé M, et al. Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer. J Exp Med. 2017;214:579-596 pubmed publisher |
Weaver J, Arandjelovic S, Brown G, K Mendu S, S Schappe M, Buckley M, et al. Hematopoietic pannexin 1 function is critical for neuropathic pain. Sci Rep. 2017;7:42550 pubmed publisher |
Endele M, Loeffler D, Kokkaliaris K, Hilsenbeck O, Skylaki S, Hoppe P, et al. CSF-1-induced Src signaling can instruct monocytic lineage choice. Blood. 2017;129:1691-1701 pubmed publisher |
Hayakawa M, Hayakawa H, Petrova T, Ritprajak P, Sutavani R, Jiménez Andrade G, et al. Loss of Functionally Redundant p38 Isoforms in T Cells Enhances Regulatory T Cell Induction. J Biol Chem. 2017;292:1762-1772 pubmed publisher |
Higuchi M, Kawamura H, Matsuki H, Hara T, Takahashi M, Saito S, et al. USP10 Is an Essential Deubiquitinase for Hematopoiesis and Inhibits Apoptosis of Long-Term Hematopoietic Stem Cells. Stem Cell Reports. 2016;7:1116-1129 pubmed publisher |
Azad A, Yin Lim S, D Costa Z, Jones K, Diana A, Sansom O, et al. PD-L1 blockade enhances response of pancreatic ductal adenocarcinoma to radiotherapy. EMBO Mol Med. 2017;9:167-180 pubmed publisher |
Gu Z, Churchman M, Roberts K, Li Y, Liu Y, Harvey R, et al. Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia. Nat Commun. 2016;7:13331 pubmed publisher |
Young K, Borikar S, Bell R, Kuffler L, Philip V, Trowbridge J. Progressive alterations in multipotent hematopoietic progenitors underlie lymphoid cell loss in aging. J Exp Med. 2016;213:2259-2267 pubmed |
Gu H, Chen C, Hao X, Wang C, Zhang X, Li Z, et al. Sorting protein VPS33B regulates exosomal autocrine signaling to mediate hematopoiesis and leukemogenesis. J Clin Invest. 2016;126:4537-4553 pubmed publisher |
Tong K, Ota K, Komuro A, Ueda T, Ito A, Anne Koch C, et al. Attenuated DNA damage repair delays therapy-related myeloid neoplasms in a mouse model. Cell Death Dis. 2016;7:e2401 pubmed publisher |
Maruyama K, Kawasaki T, Hamaguchi M, Hashimoto M, Furu M, Ito H, et al. Bone-protective Functions of Netrin 1 Protein. J Biol Chem. 2016;291:23854-23868 pubmed |
Sykes D, Kfoury Y, Mercier F, Wawer M, Law J, Haynes M, et al. Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia. Cell. 2016;167:171-186.e15 pubmed publisher |
Niu S, Bian Z, Tremblay A, Luo Y, Kidder K, Mansour A, et al. Broad Infiltration of Macrophages Leads to a Proinflammatory State in Streptozotocin-Induced Hyperglycemic Mice. J Immunol. 2016;197:3293-3301 pubmed |
Janowski A, Colegio O, Hornick E, McNiff J, Martin M, Badovinac V, et al. NLRC4 suppresses melanoma tumor progression independently of inflammasome activation. J Clin Invest. 2016;126:3917-3928 pubmed publisher |
Liu Q, Chen L, Atkinson J, Claxton D, Wang H. Atg5-dependent autophagy contributes to the development of acute myeloid leukemia in an MLL-AF9-driven mouse model. Cell Death Dis. 2016;7:e2361 pubmed publisher |
Choi J, Kim Y, Park K, Nah J, Yoon S, Kim D, et al. MicroRNA-139-5p regulates proliferation of hematopoietic progenitors and is repressed during BCR-ABL-mediated leukemogenesis. Blood. 2016;128:2117-2129 pubmed |
Matsumura K, Iwai H, Kato Miyazawa M, Kirikae F, Zhao J, Yanagawa T, et al. Peroxiredoxin 1 Contributes to Host Defenses against Mycobacterium tuberculosis. J Immunol. 2016;197:3233-3244 pubmed |
Chen X, Nie Y, Xiao H, Bian Z, Scarzello A, Song N, et al. TNFR2 expression by CD4 effector T cells is required to induce full-fledged experimental colitis. Sci Rep. 2016;6:32834 pubmed publisher |
Bhattacharya N, Yuan R, Prestwood T, Penny H, DiMaio M, Reticker Flynn N, et al. Normalizing Microbiota-Induced Retinoic Acid Deficiency Stimulates Protective CD8(+) T Cell-Mediated Immunity in Colorectal Cancer. Immunity. 2016;45:641-655 pubmed publisher |
Zhang H, Li S. Induction of Chronic Myeloid Leukemia in Mice. Methods Mol Biol. 2016;1465:17-25 pubmed publisher |
Luo M, Zhou S, Feng D, Xiao J, Li W, Xu C, et al. Runt-related Transcription Factor 1 (RUNX1) Binds to p50 in Macrophages and Enhances TLR4-triggered Inflammation and Septic Shock. J Biol Chem. 2016;291:22011-22020 pubmed |
Kristiansen T, Jaensson Gyllenbäck E, Zriwil A, Bjorklund T, Daniel J, Sitnicka E, et al. Cellular Barcoding Links B-1a B Cell Potential to a Fetal Hematopoietic Stem Cell State at the Single-Cell Level. Immunity. 2016;45:346-57 pubmed publisher |
Goplen N, Saxena V, Knudson K, Schrum A, Gil D, Daniels M, et al. IL-12 Signals through the TCR To Support CD8 Innate Immune Responses. J Immunol. 2016;197:2434-43 pubmed publisher |
Ding X, Ray Chaudhuri A, Callen E, Pang Y, Biswas K, Klarmann K, et al. Synthetic viability by BRCA2 and PARP1/ARTD1 deficiencies. Nat Commun. 2016;7:12425 pubmed publisher |
Koh B, Hufford M, Pham D, Olson M, Wu T, Jabeen R, et al. The ETS Family Transcription Factors Etv5 and PU.1 Function in Parallel To Promote Th9 Cell Development. J Immunol. 2016;197:2465-72 pubmed publisher |
Liu W, Kang S, Huang Z, Wu C, Jin H, Maine C, et al. A miR-155-Peli1-c-Rel pathway controls the generation and function of T follicular helper cells. J Exp Med. 2016;213:1901-19 pubmed publisher |
Lai M, Gonzalez Martin A, Cooper A, Oda H, Jin H, Shepherd J, et al. Regulation of B-cell development and tolerance by different members of the miR-17∼92 family microRNAs. Nat Commun. 2016;7:12207 pubmed publisher |
Kang J, Park S, Jeong S, Han M, Lee C, Lee K, et al. Epigenetic regulation of Kcna3-encoding Kv1.3 potassium channel by cereblon contributes to regulation of CD4+ T-cell activation. Proc Natl Acad Sci U S A. 2016;113:8771-6 pubmed publisher |
Yang H, Barbi J, Wu C, Zheng Y, Vignali P, Wu X, et al. MicroRNA-17 Modulates Regulatory T Cell Function by Targeting Co-regulators of the Foxp3 Transcription Factor. Immunity. 2016;45:83-93 pubmed publisher |
George J, Uyar A, Young K, Kuffler L, Waldron Francis K, Márquez E, et al. Leukaemia cell of origin identified by chromatin landscape of bulk tumour cells. Nat Commun. 2016;7:12166 pubmed publisher |
Ichiyama K, Gonzalez Martin A, Kim B, Jin H, Jin W, Xu W, et al. The MicroRNA-183-96-182 Cluster Promotes T Helper 17 Cell Pathogenicity by Negatively Regulating Transcription Factor Foxo1 Expression. Immunity. 2016;44:1284-98 pubmed publisher |
Pikman Y, Puissant A, Alexe G, Furman A, Chen L, Frumm S, et al. Targeting MTHFD2 in acute myeloid leukemia. J Exp Med. 2016;213:1285-306 pubmed publisher |
Su P, Chen S, Zheng Y, Zhou H, Yan C, Yu F, et al. Novel Function of Extracellular Matrix Protein 1 in Suppressing Th17 Cell Development in Experimental Autoimmune Encephalomyelitis. J Immunol. 2016;197:1054-64 pubmed publisher |
Singh S, Moirangthem R, Vaidya A, Jalnapurkar S, Limaye L, Kale V. AKT Signaling Prevailing in Mesenchymal Stromal Cells Modulates the Functionality of Hematopoietic Stem Cells via Intercellular Communication. Stem Cells. 2016;34:2354-67 pubmed publisher |
Chen I, Caprioli A, Ohnuki H, Kwak H, Porcher C, Tosato G. EphrinB2 regulates the emergence of a hemogenic endothelium from the aorta. Sci Rep. 2016;6:27195 pubmed publisher |
Kawalkowska J, Quirke A, Ghari F, Davis S, Subramanian V, Thompson P, et al. Abrogation of collagen-induced arthritis by a peptidyl arginine deiminase inhibitor is associated with modulation of T cell-mediated immune responses. Sci Rep. 2016;6:26430 pubmed publisher |
Brandstätter O, Schanz O, Vorac J, König J, Mori T, Maruyama T, et al. Balancing intestinal and systemic inflammation through cell type-specific expression of the aryl hydrocarbon receptor repressor. Sci Rep. 2016;6:26091 pubmed publisher |
Aggelakopoulou M, Kourepini E, Paschalidis N, Panoutsakopoulou V. ER? in CD4+ T Cells Is Crucial for Ligand-Mediated Suppression of Central Nervous System Autoimmunity. J Immunol. 2016;196:4947-56 pubmed publisher |
Brucklacher Waldert V, Ferreira C, Innocentin S, Kamdar S, Withers D, Kullberg M, et al. Tbet or Continued RORγt Expression Is Not Required for Th17-Associated Immunopathology. J Immunol. 2016;196:4893-904 pubmed publisher |
Speth J, Bourdonnay E, Penke L, Mancuso P, Moore B, Weinberg J, et al. Alveolar Epithelial Cell-Derived Prostaglandin E2 Serves as a Request Signal for Macrophage Secretion of Suppressor of Cytokine Signaling 3 during Innate Inflammation. J Immunol. 2016;196:5112-20 pubmed publisher |
Bannard O, McGowan S, Ersching J, Ishido S, Victora G, Shin J, et al. Ubiquitin-mediated fluctuations in MHC class II facilitate efficient germinal center B cell responses. J Exp Med. 2016;213:993-1009 pubmed publisher |
Peng C, Li S. Chronic Myeloid Leukemia (CML) Mouse Model in Translational Research. Methods Mol Biol. 2016;1438:225-43 pubmed publisher |
Zhang C, Xin H, Zhang W, Yazaki P, Zhang Z, Le K, et al. CD5 Binds to Interleukin-6 and Induces a Feed-Forward Loop with the Transcription Factor STAT3 in B Cells to Promote Cancer. Immunity. 2016;44:913-923 pubmed publisher |
Matthews S, McMillan S, Colbert J, Lawrence R, Watts C. Cystatin F Ensures Eosinophil Survival by Regulating Granule Biogenesis. Immunity. 2016;44:795-806 pubmed publisher |
Puram R, Kowalczyk M, de Boer C, Schneider R, Miller P, McConkey M, et al. Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML. Cell. 2016;165:303-16 pubmed publisher |
Pasi S, Kant R, Surolia A. Toll/Interleukin-1 Receptor Domain Derived from TcpC (TIR-TcpC) Ameliorates Experimental Autoimmune Arthritis by Down-modulating Th17 Cell Response. J Biol Chem. 2016;291:12358-69 pubmed publisher |
Kourepini E, Paschalidis N, Simoes D, Aggelakopoulou M, Grogan J, Panoutsakopoulou V. TIGIT Enhances Antigen-Specific Th2 Recall Responses and Allergic Disease. J Immunol. 2016;196:3570-80 pubmed publisher |
Baba T, Tanabe Y, Yoshikawa S, Yamanishi Y, Morishita S, Komatsu N, et al. MIP-1α/CCL3-expressing basophil-lineage cells drive the leukemic hematopoiesis of chronic myeloid leukemia in mice. Blood. 2016;127:2607-17 pubmed publisher |
Barros Martins J, Schmolka N, Fontinha D, Pires de Miranda M, Simas J, Brok I, et al. Effector γδ T Cell Differentiation Relies on Master but Not Auxiliary Th Cell Transcription Factors. J Immunol. 2016;196:3642-52 pubmed publisher |
Olson M, Verdan F, Hufford M, Dent A, Kaplan M. STAT3 Impairs STAT5 Activation in the Development of IL-9-Secreting T Cells. J Immunol. 2016;196:3297-304 pubmed publisher |
Tang D, Tao S, Chen Z, Koliesnik I, Calmes P, Hoerr V, et al. Dietary restriction improves repopulation but impairs lymphoid differentiation capacity of hematopoietic stem cells in early aging. J Exp Med. 2016;213:535-53 pubmed publisher |
Gomez Rodriguez J, Meylan F, Handon R, Hayes E, Anderson S, Kirby M, et al. Itk is required for Th9 differentiation via TCR-mediated induction of IL-2 and IRF4. Nat Commun. 2016;7:10857 pubmed publisher |
Woo J, Srikanth S, Nishi M, Ping P, Takeshima H, Gwack Y. Junctophilin-4, a component of the endoplasmic reticulum-plasma membrane junctions, regulates Ca2+ dynamics in T cells. Proc Natl Acad Sci U S A. 2016;113:2762-7 pubmed publisher |
Radtke D, Lacher S, Szumilas N, Sandrock L, Ackermann J, Nitschke L, et al. Grb2 Is Important for T Cell Development, Th Cell Differentiation, and Induction of Experimental Autoimmune Encephalomyelitis. J Immunol. 2016;196:2995-3005 pubmed publisher |
Jones L, Alli R, Li B, Geiger T. Differential T Cell Cytokine Receptivity and Not Signal Quality Distinguishes IL-6 and IL-10 Signaling during Th17 Differentiation. J Immunol. 2016;196:2973-85 pubmed publisher |
Rossaint J, Oehmichen J, Van Aken H, Reuter S, Pavenstädt H, Meersch M, et al. FGF23 signaling impairs neutrophil recruitment and host defense during CKD. J Clin Invest. 2016;126:962-74 pubmed publisher |
Mascarenhas M, Bacon W, Kapeni C, Fitch S, Kimber G, Cheng S, et al. Analysis of Jak2 signaling reveals resistance of mouse embryonic hematopoietic stem cells to myeloproliferative disease mutation. Blood. 2016;127:2298-309 pubmed publisher |
White Y, Bagchi A, Van Ziffle J, Inguva A, Bollag G, Zhang C, et al. KRAS insertion mutations are oncogenic and exhibit distinct functional properties. Nat Commun. 2016;7:10647 pubmed publisher |
Liu J, Copland D, Theodoropoulou S, Chiu H, Barba M, Mak K, et al. Impairing autophagy in retinal pigment epithelium leads to inflammasome activation and enhanced macrophage-mediated angiogenesis. Sci Rep. 2016;6:20639 pubmed publisher |
Leszczyńska A, O Doherty A, Farrell E, Pindjáková J, O Brien F, O BRIEN T, et al. Differentiation of Vascular Stem Cells Contributes to Ectopic Calcification of Atherosclerotic Plaque. Stem Cells. 2016;34:913-23 pubmed publisher |
Cho S, Wu C, Yasuda T, Cruz L, Khan A, Lin L, et al. miR-23∼27∼24 clusters control effector T cell differentiation and function. J Exp Med. 2016;213:235-49 pubmed publisher |
Chin D, Sakurai M, Nah G, Du L, Jacob B, Yokomizo T, et al. RUNX1 haploinsufficiency results in granulocyte colony-stimulating factor hypersensitivity. Blood Cancer J. 2016;6:e379 pubmed publisher |
Hou Y, Feng Q, Xu M, Li G, Liu X, Sheng Z, et al. High-dose dexamethasone corrects impaired myeloid-derived suppressor cell function via Ets1 in immune thrombocytopenia. Blood. 2016;127:1587-97 pubmed publisher |
Schulze I, Rohde C, Scheller Wendorff M, Bäumer N, Krause A, Herbst F, et al. Increased DNA methylation of Dnmt3b targets impairs leukemogenesis. Blood. 2016;127:1575-86 pubmed publisher |
Wenge D, Felipe Fumero E, Angenendt L, Schliemann C, Schmidt E, Schmidt L, et al. MN1-Fli1 oncofusion transforms murine hematopoietic progenitor cells into acute megakaryoblastic leukemia cells. Oncogenesis. 2015;4:e179 pubmed publisher |
Guerrini M, Okamoto K, Komatsu N, Sawa S, Danks L, Penninger J, et al. Inhibition of the TNF Family Cytokine RANKL Prevents Autoimmune Inflammation in the Central Nervous System. Immunity. 2015;43:1174-85 pubmed publisher |
Kaufmann U, Shaw P, Kozhaya L, Subramanian R, Gaida K, Unutmaz D, et al. Selective ORAI1 Inhibition Ameliorates Autoimmune Central Nervous System Inflammation by Suppressing Effector but Not Regulatory T Cell Function. J Immunol. 2016;196:573-85 pubmed publisher |
Zheng H, Tan Z, Zhou T, Zhu F, Ding Y, Liu T, et al. The TLR2 is activated by sporozoites and suppresses intrahepatic rodent malaria parasite development. Sci Rep. 2015;5:18239 pubmed publisher |
Hatlen M, Arora K, Vacic V, Grabowska E, Liao W, Riley Gillis B, et al. Integrative genetic analysis of mouse and human AML identifies cooperating disease alleles. J Exp Med. 2016;213:25-34 pubmed publisher |
Haetscher N, Feuermann Y, Wingert S, Rehage M, Thalheimer F, Weiser C, et al. STAT5-regulated microRNA-193b controls haematopoietic stem and progenitor cell expansion by modulating cytokine receptor signalling. Nat Commun. 2015;6:8928 pubmed publisher |
Heiseke A, Jeuk B, Markota A, Straub T, Lehr H, Reindl W, et al. IRAK1 Drives Intestinal Inflammation by Promoting the Generation of Effector Th Cells with Optimal Gut-Homing Capacity. J Immunol. 2015;195:5787-94 pubmed publisher |
Ungari S, Montepeloso A, Morena F, Cocchiarella F, Recchia A, Martino S, et al. Design of a regulated lentiviral vector for hematopoietic stem cell gene therapy of globoid cell leukodystrophy. Mol Ther Methods Clin Dev. 2015;2:15038 pubmed publisher |
Cimen Bozkus C, Elzey B, Crist S, Ellies L, Ratliff T. Expression of Cationic Amino Acid Transporter 2 Is Required for Myeloid-Derived Suppressor Cell-Mediated Control of T Cell Immunity. J Immunol. 2015;195:5237-50 pubmed publisher |
Mullenders J, Aranda Orgilles B, Lhoumaud P, Keller M, Pae J, Wang K, et al. Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms. J Exp Med. 2015;212:1833-50 pubmed publisher |
Cook K, Shpargel K, Starmer J, Whitfield Larry F, Conley B, Allard D, et al. T Follicular Helper Cell-Dependent Clearance of a Persistent Virus Infection Requires T Cell Expression of the Histone Demethylase UTX. Immunity. 2015;43:703-14 pubmed publisher |
Xiao Y, Qiao G, Tang J, Tang R, Guo H, Warwar S, et al. Protein Tyrosine Phosphatase SHP-1 Modulates T Cell Responses by Controlling Cbl-b Degradation. J Immunol. 2015;195:4218-27 pubmed publisher |
Han C, Nie Y, Lian H, Liu R, He F, Huang H, et al. Acute inflammation stimulates a regenerative response in the neonatal mouse heart. Cell Res. 2015;25:1137-51 pubmed publisher |
Neri T, Muggeo S, Paulis M, Caldana M, Crisafulli L, Strina D, et al. Targeted Gene Correction in Osteopetrotic-Induced Pluripotent Stem Cells for the Generation of Functional Osteoclasts. Stem Cell Reports. 2015;5:558-68 pubmed publisher |
Duque Afonso J, Feng J, Scherer F, Lin C, Wong S, Wang Z, et al. Comparative genomics reveals multistep pathogenesis of E2A-PBX1 acute lymphoblastic leukemia. J Clin Invest. 2015;125:3667-80 pubmed publisher |
Miller P, Bonn M, McKarns S. Transmembrane TNF-TNFR2 Impairs Th17 Differentiation by Promoting Il2 Expression. J Immunol. 2015;195:2633-47 pubmed publisher |
Arbelaez C, Glatigny S, Duhen R, Eberl G, Oukka M, Bettelli E. IL-7/IL-7 Receptor Signaling Differentially Affects Effector CD4+ T Cell Subsets Involved in Experimental Autoimmune Encephalomyelitis. J Immunol. 2015;195:1974-83 pubmed publisher |
Viret C, Mahiddine K, Baker R, Haskins K, Guerder S. The T Cell Repertoire-Diversifying Enzyme TSSP Contributes to Thymic Selection of Diabetogenic CD4 T Cell Specificities Reactive to ChgA and IAPP Autoantigens. J Immunol. 2015;195:1964-73 pubmed publisher |
Lin W, Yuan N, Wang Z, Cao Y, Fang Y, Li X, et al. Autophagy confers DNA damage repair pathways to protect the hematopoietic system from nuclear radiation injury. Sci Rep. 2015;5:12362 pubmed publisher |
Yoon J, Sudo K, Kuroda M, Kato M, Lee I, Han J, et al. Phosphorylation status determines the opposing functions of Smad2/Smad3 as STAT3 cofactors in TH17 differentiation. Nat Commun. 2015;6:7600 pubmed publisher |
Lainé A, Martin B, Luka M, Mir L, Auffray C, Lucas B, et al. Foxo1 Is a T Cell-Intrinsic Inhibitor of the RORγt-Th17 Program. J Immunol. 2015;195:1791-803 pubmed publisher |
Balasubramani A, Larjo A, Bassein J, Chang X, Hastie R, Togher S, et al. Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1-BAP1 complex. Nat Commun. 2015;6:7307 pubmed publisher |
Barnes M, Li C, Xu Y, An J, Huang Y, Cyster J. The lysophosphatidylserine receptor GPR174 constrains regulatory T cell development and function. J Exp Med. 2015;212:1011-20 pubmed publisher |
Regha K, Assi S, Tsoulaki O, Gilmour J, Lacaud G, Bonifer C. Developmental-stage-dependent transcriptional response to leukaemic oncogene expression. Nat Commun. 2015;6:7203 pubmed publisher |
Thakur R, Trivedi R, Rastogi N, Singh M, Mishra D. Inhibition of STAT3, FAK and Src mediated signaling reduces cancer stem cell load, tumorigenic potential and metastasis in breast cancer. Sci Rep. 2015;5:10194 pubmed publisher |
Ebel M, Awe O, Kaplan M, Kansas G. Diverse inflammatory cytokines induce selectin ligand expression on murine CD4 T cells via p38α MAPK. J Immunol. 2015;194:5781-8 pubmed publisher |
Lim H, Kang S, Ryu J, Schilling B, Fei M, Lee I, et al. SIRT1 deacetylates RORγt and enhances Th17 cell generation. J Exp Med. 2015;212:607-17 pubmed publisher |
Cook P, Owen H, Deaton A, Borger J, Brown S, Clouaire T, et al. A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells. Nat Commun. 2015;6:6920 pubmed publisher |
Hadland B, Varnum Finney B, Poulos M, Moon R, Butler J, Rafii S, et al. Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros-derived hematopoietic stem cells. J Clin Invest. 2015;125:2032-45 pubmed publisher |
Ichiyama K, Chen T, Wang X, Yan X, Kim B, Tanaka S, et al. The methylcytosine dioxygenase Tet2 promotes DNA demethylation and activation of cytokine gene expression in T cells. Immunity. 2015;42:613-26 pubmed publisher |
Zang G, Sandberg M, Carlsson P, Welsh N, Jansson L, Barbu A. Activated pancreatic stellate cells can impair pancreatic islet function in mice. Ups J Med Sci. 2015;120:169-80 pubmed publisher |
Tsukamoto H, Senju S, Matsumura K, Swain S, Nishimura Y. IL-6-mediated environmental conditioning of defective Th1 differentiation dampens antitumour immune responses in old age. Nat Commun. 2015;6:6702 pubmed publisher |
Bourdonnay E, Zasłona Z, Penke L, Speth J, Schneider D, Przybranowski S, et al. Transcellular delivery of vesicular SOCS proteins from macrophages to epithelial cells blunts inflammatory signaling. J Exp Med. 2015;212:729-42 pubmed publisher |
Del Blanco B, Angulo Ã, Krangel M, Hernández Munain C. T-cell receptor α enhancer is inactivated in αβ T lymphocytes. Proc Natl Acad Sci U S A. 2015;112:E1744-53 pubmed publisher |
Kosoff R, Aslan J, Kostyak J, Dulaimi E, Chow H, Prudnikova T, et al. Pak2 restrains endomitosis during megakaryopoiesis and alters cytoskeleton organization. Blood. 2015;125:2995-3005 pubmed publisher |
Chen Z, Shojaee S, Buchner M, Geng H, Lee J, Klemm L, et al. Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature. 2015;521:357-61 pubmed publisher |
Bornancin F, Renner F, Touil R, Sic H, Kolb Y, Touil Allaoui I, et al. Deficiency of MALT1 paracaspase activity results in unbalanced regulatory and effector T and B cell responses leading to multiorgan inflammation. J Immunol. 2015;194:3723-34 pubmed publisher |
Buchner M, Park E, Geng H, Klemm L, Flach J, Passegué E, et al. Identification of FOXM1 as a therapeutic target in B-cell lineage acute lymphoblastic leukaemia. Nat Commun. 2015;6:6471 pubmed publisher |
Roychoudhury J, Clark J, Gracia Maldonado G, Unnisa Z, Wunderlich M, Link K, et al. MEIS1 regulates an HLF-oxidative stress axis in MLL-fusion gene leukemia. Blood. 2015;125:2544-52 pubmed publisher |
Reppert S, Zinser E, Holzinger C, Sandrock L, Koch S, Finotto S. NFATc1 deficiency in T cells protects mice from experimental autoimmune encephalomyelitis. Eur J Immunol. 2015;45:1426-40 pubmed publisher |
Di Savino A, Panuzzo C, Rocca S, Familiari U, Piazza R, Crivellaro S, et al. Morgana acts as an oncosuppressor in chronic myeloid leukemia. Blood. 2015;125:2245-53 pubmed publisher |
Boland B, Widjaja C, Banno A, Zhang B, Kim S, Stoven S, et al. Immunodeficiency and autoimmune enterocolopathy linked to NFAT5 haploinsufficiency. J Immunol. 2015;194:2551-60 pubmed publisher |
Park S, Gönen M, Vu L, Minuesa G, Tivnan P, Barlowe T, et al. Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program. J Clin Invest. 2015;125:1286-98 pubmed publisher |
Choi J, Jeon S, Choi S, Park K, Seong R. The SWI/SNF chromatin remodeling complex regulates germinal center formation by repressing Blimp-1 expression. Proc Natl Acad Sci U S A. 2015;112:E718-27 pubmed publisher |
Hill E, Ng T, Burton B, Oakley C, Malik K, Wraith D. Glycogen synthase kinase-3 controls IL-10 expression in CD4(+) effector T-cell subsets through epigenetic modification of the IL-10 promoter. Eur J Immunol. 2015;45:1103-15 pubmed publisher |
Smith D, Liu S, Ji S, Li B, McLaughlin J, Cheng D, et al. Genetic engineering of hematopoietic stem cells to generate invariant natural killer T cells. Proc Natl Acad Sci U S A. 2015;112:1523-8 pubmed publisher |
Yáñez A, Ng M, Hassanzadeh Kiabi N, Goodridge H. IRF8 acts in lineage-committed rather than oligopotent progenitors to control neutrophil vs monocyte production. Blood. 2015;125:1452-9 pubmed publisher |
Grisouard J, Shimizu T, Duek A, Kubovcakova L, Hao Shen H, Dirnhofer S, et al. Deletion of Stat3 in hematopoietic cells enhances thrombocytosis and shortens survival in a JAK2-V617F mouse model of MPN. Blood. 2015;125:2131-40 pubmed publisher |
Zeng Y, Broxmeyer H, Staser K, Chitteti B, Park S, Hahn S, et al. Pak2 regulates hematopoietic progenitor cell proliferation, survival, and differentiation. Stem Cells. 2015;33:1630-41 pubmed publisher |
Vallabhaneni H, Zhou F, Maul R, Sarkar J, Yin J, Lei M, et al. Defective repair of uracil causes telomere defects in mouse hematopoietic cells. J Biol Chem. 2015;290:5502-11 pubmed publisher |
Gorbacheva V, Fan R, Wang X, Baldwin W, Fairchild R, Valujskikh A. IFN-γ production by memory helper T cells is required for CD40-independent alloantibody responses. J Immunol. 2015;194:1347-56 pubmed publisher |
Gobbetti T, Coldewey S, Chen J, McArthur S, Le Faouder P, Cenac N, et al. Nonredundant protective properties of FPR2/ALX in polymicrobial murine sepsis. Proc Natl Acad Sci U S A. 2014;111:18685-90 pubmed publisher |
Stoycheva D, Deiser K, Stärck L, Nishanth G, Schlüter D, Uckert W, et al. IFN-γ regulates CD8+ memory T cell differentiation and survival in response to weak, but not strong, TCR signals. J Immunol. 2015;194:553-9 pubmed publisher |
Xiao N, Laha S, Das S, Morlock K, Jesneck J, Raffel G. Ott1 (Rbm15) regulates thrombopoietin response in hematopoietic stem cells through alternative splicing of c-Mpl. Blood. 2015;125:941-8 pubmed publisher |
Reynolds A, Kuraoka M, Kelsoe G. Natural IgM is produced by CD5- plasma cells that occupy a distinct survival niche in bone marrow. J Immunol. 2015;194:231-42 pubmed publisher |
Beck T, Gomes A, Cyster J, Pereira J. CXCR4 and a cell-extrinsic mechanism control immature B lymphocyte egress from bone marrow. J Exp Med. 2014;211:2567-81 pubmed publisher |
Tanaka S, Tanaka K, Magnusson F, Chung Y, Martinez G, Wang Y, et al. CCAAT/enhancer-binding protein ? negatively regulates IFN-? expression in T cells. J Immunol. 2014;193:6152-60 pubmed publisher |
Tang W, Wang H, Claudio E, Tassi I, Ha H, Saret S, et al. The oncoprotein and transcriptional regulator Bcl-3 governs plasticity and pathogenicity of autoimmune T cells. Immunity. 2014;41:555-66 pubmed publisher |
LU E, McLellan M, Ding L, Fulton R, Mardis E, Wilson R, et al. Caspase-9 is required for normal hematopoietic development and protection from alkylator-induced DNA damage in mice. Blood. 2014;124:3887-95 pubmed publisher |
Bilbao D, Luciani L, Johannesson B, Piszczek A, Rosenthal N. Insulin-like growth factor-1 stimulates regulatory T cells and suppresses autoimmune disease. EMBO Mol Med. 2014;6:1423-35 pubmed publisher |
Wegiel B, Larsen R, Gallo D, Chin B, Harris C, Mannam P, et al. Macrophages sense and kill bacteria through carbon monoxide-dependent inflammasome activation. J Clin Invest. 2014;124:4926-40 pubmed publisher |
Pawlikowska P, Fouchet P, Vainchenker W, Rosselli F, Naim V. Defective endomitosis during megakaryopoiesis leads to thrombocytopenia in Fanca-/- mice. Blood. 2014;124:3613-23 pubmed publisher |
Chu C, Wang Y, Zhang X, Ni X, Cao J, Xu W, et al. SAP-regulated T Cell-APC adhesion and ligation-dependent and -independent Ly108-CD3ζ interactions. J Immunol. 2014;193:3860-71 pubmed publisher |
Degryse S, de Bock C, Cox L, Demeyer S, Gielen O, Mentens N, et al. JAK3 mutants transform hematopoietic cells through JAK1 activation, causing T-cell acute lymphoblastic leukemia in a mouse model. Blood. 2014;124:3092-100 pubmed publisher |
Pawaria S, Ramani K, Maers K, Liu Y, Kane L, Levesque M, et al. Complement component C5a permits the coexistence of pathogenic Th17 cells and type I IFN in lupus. J Immunol. 2014;193:3288-95 pubmed publisher |
Sprissler C, Belenki D, Maurer H, Aumann K, Pfeifer D, Klein C, et al. Depletion of STAT5 blocks TEL-SYK-induced APMF-type leukemia with myelofibrosis and myelodysplasia in mice. Blood Cancer J. 2014;4:e240 pubmed publisher |
Watanabe Y, Onodera A, Kanai U, Ichikawa T, Obata Ninomiya K, Wada T, et al. Trithorax complex component Menin controls differentiation and maintenance of T helper 17 cells. Proc Natl Acad Sci U S A. 2014;111:12829-34 pubmed publisher |
Li X, Liang Y, Leblanc M, Benner C, Zheng Y. Function of a Foxp3 cis-element in protecting regulatory T cell identity. Cell. 2014;158:734-748 pubmed publisher |
Lancini C, van den Berk P, Vissers J, Gargiulo G, Song J, Hulsman D, et al. Tight regulation of ubiquitin-mediated DNA damage response by USP3 preserves the functional integrity of hematopoietic stem cells. J Exp Med. 2014;211:1759-77 pubmed publisher |
Accornero F, Kanisicak O, Tjondrokoesoemo A, Attia A, McNally E, Molkentin J. Myofiber-specific inhibition of TGF? signaling protects skeletal muscle from injury and dystrophic disease in mice. Hum Mol Genet. 2014;23:6903-15 pubmed publisher |
Dong C, Liu X, Wang N, Wang L, Yang B, Ren Q, et al. Twist-1, a novel regulator of hematopoietic stem cell self-renewal and myeloid lineage development. Stem Cells. 2014;32:3173-82 pubmed publisher |
Glosson Byers N, Sehra S, Stritesky G, Yu Q, Awe O, Pham D, et al. Th17 cells demonstrate stable cytokine production in a proallergic environment. J Immunol. 2014;193:2631-40 pubmed publisher |
Tanaka S, Suto A, Iwamoto T, Kashiwakuma D, Kagami S, Suzuki K, et al. Sox5 and c-Maf cooperatively induce Th17 cell differentiation via ROR?t induction as downstream targets of Stat3. J Exp Med. 2014;211:1857-74 pubmed publisher |
Okoye I, Czieso S, Ktistaki E, Roderick K, Coomes S, Pelly V, et al. Transcriptomics identified a critical role for Th2 cell-intrinsic miR-155 in mediating allergy and antihelminth immunity. Proc Natl Acad Sci U S A. 2014;111:E3081-90 pubmed publisher |
Shi J, Kundrat L, Pishesha N, Bilate A, Theile C, Maruyama T, et al. Engineered red blood cells as carriers for systemic delivery of a wide array of functional probes. Proc Natl Acad Sci U S A. 2014;111:10131-6 pubmed publisher |
Glenn J, Smith M, Calabresi P, Whartenby K. Mesenchymal stem cells differentially modulate effector CD8+ T cell subsets and exacerbate experimental autoimmune encephalomyelitis. Stem Cells. 2014;32:2744-55 pubmed publisher |
Hou Y, Lin H, Zhu L, Liu Z, Hu F, Shi J, et al. The inhibitory effect of IFN-? on protease HTRA1 expression in rheumatoid arthritis. J Immunol. 2014;193:130-8 pubmed publisher |
Ke F, Zhang L, Liu Z, Liu J, Yan S, Xu Z, et al. Autocrine interleukin-6 drives skin-derived mesenchymal stem cell trafficking via regulating voltage-gated Ca(2+) channels. Stem Cells. 2014;32:2799-810 pubmed publisher |
Herrmann A, Priceman S, Swiderski P, Kujawski M, Xin H, Cherryholmes G, et al. CTLA4 aptamer delivers STAT3 siRNA to tumor-associated and malignant T cells. J Clin Invest. 2014;124:2977-87 pubmed publisher |
Cunningham J, Moreno M, Lodi A, Ronen S, Ruggero D. Protein and nucleotide biosynthesis are coupled by a single rate-limiting enzyme, PRPS2, to drive cancer. Cell. 2014;157:1088-103 pubmed publisher |
Choi S, Kim B, Robinson J, Fink S, Yan M, Sporn M, et al. Synthetic triterpenoid induces 15-PGDH expression and suppresses inflammation-driven colon carcinogenesis. J Clin Invest. 2014;124:2472-82 pubmed publisher |
Lu H, Fang E, Sykora P, Kulikowicz T, Zhang Y, Becker K, et al. Senescence induced by RECQL4 dysfunction contributes to Rothmund-Thomson syndrome features in mice. Cell Death Dis. 2014;5:e1226 pubmed publisher |
Kaiser W, Daley Bauer L, Thapa R, Mandal P, Berger S, Huang C, et al. RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition. Proc Natl Acad Sci U S A. 2014;111:7753-8 pubmed publisher |
Komeno Y, Yan M, Matsuura S, Lam K, Lo M, Huang Y, et al. Runx1 exon 6-related alternative splicing isoforms differentially regulate hematopoiesis in mice. Blood. 2014;123:3760-9 pubmed publisher |
Piunti A, Rossi A, Cerutti A, Albert M, Jammula S, Scelfo A, et al. Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication. Nat Commun. 2014;5:3649 pubmed publisher |
Cortez V, Cervantes Barragan L, Song C, Gilfillan S, McDonald K, Tussiwand R, et al. CRTAM controls residency of gut CD4+CD8+ T cells in the steady state and maintenance of gut CD4+ Th17 during parasitic infection. J Exp Med. 2014;211:623-33 pubmed publisher |
Nagashima H, Okuyama Y, Asao A, Kawabe T, Yamaki S, Nakano H, et al. The adaptor TRAF5 limits the differentiation of inflammatory CD4(+) T cells by antagonizing signaling via the receptor for IL-6. Nat Immunol. 2014;15:449-56 pubmed publisher |
Wu J, Yang J, Yang K, Wang H, Gorentla B, Shin J, et al. iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions. J Clin Invest. 2014;124:1685-98 pubmed publisher |
Jie Z, Liang Y, Hou L, Dong C, Iwakura Y, Soong L, et al. Intrahepatic innate lymphoid cells secrete IL-17A and IL-17F that are crucial for T cell priming in viral infection. J Immunol. 2014;192:3289-300 pubmed publisher |
Gomez Rodriguez J, Wohlfert E, Handon R, Meylan F, Wu J, Anderson S, et al. Itk-mediated integration of T cell receptor and cytokine signaling regulates the balance between Th17 and regulatory T cells. J Exp Med. 2014;211:529-43 pubmed publisher |
Keiffer T, Bond J. Meprin metalloproteases inactivate interleukin 6. J Biol Chem. 2014;289:7580-8 pubmed publisher |
Kusy S, Contag C. Reporter gene technologies for imaging cell fates in hematopoiesis. Methods Mol Biol. 2014;1109:1-22 pubmed publisher |
Shin J, Hu W, Naramura M, Park C. High c-Kit expression identifies hematopoietic stem cells with impaired self-renewal and megakaryocytic bias. J Exp Med. 2014;211:217-31 pubmed publisher |
Ikeda S, Saijo S, Murayama M, Shimizu K, Akitsu A, Iwakura Y. Excess IL-1 signaling enhances the development of Th17 cells by downregulating TGF-?-induced Foxp3 expression. J Immunol. 2014;192:1449-58 pubmed publisher |
Nakaya Y, Shide K, Naito H, Niwa T, Horio T, Miyake J, et al. Effect of NS-018, a selective JAK2V617F inhibitor, in a murine model of myelofibrosis. Blood Cancer J. 2014;4:e174 pubmed publisher |
Li L, Zhang J, Diao W, Wang D, Wei Y, Zhang C, et al. MicroRNA-155 and MicroRNA-21 promote the expansion of functional myeloid-derived suppressor cells. J Immunol. 2014;192:1034-43 pubmed publisher |
Ohlsson E, Hasemann M, Willer A, Lauridsen F, Rapin N, Jendholm J, et al. Initiation of MLL-rearranged AML is dependent on C/EBP?. J Exp Med. 2014;211:5-13 pubmed publisher |
Lopez M, Meier D, Muller A, Franken P, Fujita J, Fontana A. Tumor necrosis factor and transforming growth factor ? regulate clock genes by controlling the expression of the cold inducible RNA-binding protein (CIRBP). J Biol Chem. 2014;289:2736-44 pubmed publisher |
Jones M, Osawa G, Regal J, Weinberg D, Taggart J, Kocak H, et al. Hematopoietic stem cells are acutely sensitive to Acd shelterin gene inactivation. J Clin Invest. 2014;124:353-66 pubmed publisher |
Kim K, Srikanth S, Tan Y, Yee M, Jew M, Damoiseaux R, et al. Calcium signaling via Orai1 is essential for induction of the nuclear orphan receptor pathway to drive Th17 differentiation. J Immunol. 2014;192:110-22 pubmed publisher |
Fisher Y, Strominger I, Biton S, Nemirovsky A, Baron R, Monsonego A. Th1 polarization of T cells injected into the cerebrospinal fluid induces brain immunosurveillance. J Immunol. 2014;192:92-102 pubmed publisher |
Stärck L, Popp K, Pircher H, Uckert W. Immunotherapy with TCR-redirected T cells: comparison of TCR-transduced and TCR-engineered hematopoietic stem cell-derived T cells. J Immunol. 2014;192:206-13 pubmed publisher |
Lee P, Puppi M, Schluns K, Yu Lee L, Dong C, Lacorazza H. The transcription factor E74-like factor 4 suppresses differentiation of proliferating CD4+ T cells to the Th17 lineage. J Immunol. 2014;192:178-88 pubmed publisher |
Roy A, Ganesh G, Sippola H, Bolin S, Sawesi O, Dagälv A, et al. Mast cell chymase degrades the alarmins heat shock protein 70, biglycan, HMGB1, and interleukin-33 (IL-33) and limits danger-induced inflammation. J Biol Chem. 2014;289:237-50 pubmed publisher |
Ng K, Hu Z, Ebrahem Q, Negrotto S, Lausen J, Saunthararajah Y. Runx1 deficiency permits granulocyte lineage commitment but impairs subsequent maturation. Oncogenesis. 2013;2:e78 pubmed publisher |
de Laval B, Pawlikowska P, Barbieri D, Besnard Guerin C, Cico A, Kumar R, et al. Thrombopoietin promotes NHEJ DNA repair in hematopoietic stem cells through specific activation of Erk and NF-?B pathways and their target, IEX-1. Blood. 2014;123:509-19 pubmed publisher |
Rolla S, Ingoglia G, Bardina V, Silengo L, Altruda F, Novelli F, et al. Acute-phase protein hemopexin is a negative regulator of Th17 response and experimental autoimmune encephalomyelitis development. J Immunol. 2013;191:5451-9 pubmed publisher |
Martin H, Mali R, Ma P, Chatterjee A, Ramdas B, Sims E, et al. Pak and Rac GTPases promote oncogenic KIT-induced neoplasms. J Clin Invest. 2013;123:4449-63 pubmed publisher |
Macdonald T, Wan Z, Frendo Cumbo S, Dyck D, Wright D. IL-6 and epinephrine have divergent fiber type effects on intramuscular lipolysis. J Appl Physiol (1985). 2013;115:1457-63 pubmed publisher |
Kawashima H, Takatori H, Suzuki K, Iwata A, Yokota M, Suto A, et al. Tumor suppressor p53 inhibits systemic autoimmune diseases by inducing regulatory T cells. J Immunol. 2013;191:3614-23 pubmed publisher |
Takeuchi H, Yokota Nakatsuma A, Ohoka Y, Kagechika H, Kato C, Song S, et al. Retinoid X receptor agonists modulate Foxp3? regulatory T cell and Th17 cell differentiation with differential dependence on retinoic acid receptor activation. J Immunol. 2013;191:3725-33 pubmed publisher |
Pham D, Walline C, Hollister K, Dent A, Blum J, Firulli A, et al. The transcription factor Twist1 limits T helper 17 and T follicular helper cell development by repressing the gene encoding the interleukin-6 receptor ? chain. J Biol Chem. 2013;288:27423-33 pubmed publisher |
Liu X, Li H, Zhong B, Blonska M, Gorjestani S, Yan M, et al. USP18 inhibits NF-?B and NFAT activation during Th17 differentiation by deubiquitinating the TAK1-TAB1 complex. J Exp Med. 2013;210:1575-90 pubmed publisher |
Sonda N, Simonato F, Peranzoni E, Calì B, Bortoluzzi S, Bisognin A, et al. miR-142-3p prevents macrophage differentiation during cancer-induced myelopoiesis. Immunity. 2013;38:1236-49 pubmed publisher |
Bose A, Barik S, Banerjee S, Ghosh T, Mallick A, Bhattacharyya Majumdar S, et al. Tumor-derived vascular pericytes anergize Th cells. J Immunol. 2013;191:971-81 pubmed publisher |
Yamashita J, Iwamura C, Ito T, Narita M, Hara Y, Sasaki T, et al. Paraoxonase-1 suppresses experimental colitis via the inhibition of IFN-? production from CD4 T cells. J Immunol. 2013;191:949-60 pubmed publisher |
Pham D, Yu Q, Walline C, Muthukrishnan R, Blum J, Kaplan M. Opposing roles of STAT4 and Dnmt3a in Th1 gene regulation. J Immunol. 2013;191:902-11 pubmed publisher |
Yi Z, Stunz L, Bishop G. TNF receptor associated factor 3 plays a key role in development and function of invariant natural killer T cells. J Exp Med. 2013;210:1079-86 pubmed publisher |
Edwards J, Fujii H, Zhou A, Creemers J, Unutmaz D, Shevach E. Regulation of the expression of GARP/latent TGF-β1 complexes on mouse T cells and their role in regulatory T cell and Th17 differentiation. J Immunol. 2013;190:5506-15 pubmed publisher |
Shieh A, Ward A, Donlan K, Harding Theobald E, Xu J, Mullighan C, et al. Defective K-Ras oncoproteins overcome impaired effector activation to initiate leukemia in vivo. Blood. 2013;121:4884-93 pubmed publisher |
Yan B, Wei J, Yuan Y, Sun R, Li D, Luo J, et al. IL-6 cooperates with G-CSF to induce protumor function of neutrophils in bone marrow by enhancing STAT3 activation. J Immunol. 2013;190:5882-93 pubmed publisher |
Beurel E, Kaidanovich Beilin O, Yeh W, Song L, Palomo V, Michalek S, et al. Regulation of Th1 cells and experimental autoimmune encephalomyelitis by glycogen synthase kinase-3. J Immunol. 2013;190:5000-11 pubmed publisher |
Heidegger S, Kirchner S, Stephan N, Bohn B, Suhartha N, Hotz C, et al. TLR activation excludes circulating naive CD8+ T cells from gut-associated lymphoid organs in mice. J Immunol. 2013;190:5313-20 pubmed publisher |
Ye P, Chen W, Wu J, Huang X, Li J, Wang S, et al. GM-CSF contributes to aortic aneurysms resulting from SMAD3 deficiency. J Clin Invest. 2013;123:2317-31 pubmed publisher |
Duhen R, Glatigny S, Arbelaez C, Blair T, Oukka M, Bettelli E. Cutting edge: the pathogenicity of IFN-γ-producing Th17 cells is independent of T-bet. J Immunol. 2013;190:4478-82 pubmed publisher |
Arteaga M, Mikesch J, Qiu J, Christensen J, Helin K, Kogan S, et al. The histone demethylase PHF8 governs retinoic acid response in acute promyelocytic leukemia. Cancer Cell. 2013;23:376-89 pubmed publisher |
Arndt K, Grinenko T, Mende N, Reichert D, Portz M, Ripich T, et al. CD133 is a modifier of hematopoietic progenitor frequencies but is dispensable for the maintenance of mouse hematopoietic stem cells. Proc Natl Acad Sci U S A. 2013;110:5582-7 pubmed publisher |
Liu B, Wang M, Wang X, Zhao D, Liu D, Liu J, et al. Liver sinusoidal endothelial cell lectin inhibits CTL-dependent virus clearance in mouse models of viral hepatitis. J Immunol. 2013;190:4185-95 pubmed publisher |
de Bruin A, Demirel O, Hooibrink B, Brandts C, Nolte M. Interferon-? impairs proliferation of hematopoietic stem cells in mice. Blood. 2013;121:3578-85 pubmed publisher |
Conway A, Scotland P, Lavau C, Wechsler D. A CALM-derived nuclear export signal is essential for CALM-AF10-mediated leukemogenesis. Blood. 2013;121:4758-68 pubmed publisher |
Paster W, Brockmeyer C, Fu G, Simister P, de Wet B, Martinez Riaño A, et al. GRB2-mediated recruitment of THEMIS to LAT is essential for thymocyte development. J Immunol. 2013;190:3749-56 pubmed publisher |
Koning J, Kooij G, de Vries H, Nolte M, Mebius R. Mesenchymal stem cells are mobilized from the bone marrow during inflammation. Front Immunol. 2013;4:49 pubmed publisher |
Wu S, Yu J, Liu F, Miaw S, Wu Hsieh B. Galectin-3 negatively regulates dendritic cell production of IL-23/IL-17-axis cytokines in infection by Histoplasma capsulatum. J Immunol. 2013;190:3427-37 pubmed publisher |
Santoro F, Botrugno O, Dal Zuffo R, Pallavicini I, Matthews G, Cluse L, et al. A dual role for Hdac1: oncosuppressor in tumorigenesis, oncogene in tumor maintenance. Blood. 2013;121:3459-68 pubmed publisher |
Raveney B, Oki S, Yamamura T. Nuclear receptor NR4A2 orchestrates Th17 cell-mediated autoimmune inflammation via IL-21 signalling. PLoS ONE. 2013;8:e56595 pubmed publisher |
May R, Okumura M, Hsu C, Bassiri H, Yang E, Rak G, et al. Murine natural killer immunoreceptors use distinct proximal signaling complexes to direct cell function. Blood. 2013;121:3135-46 pubmed publisher |
Lobry C, Ntziachristos P, Ndiaye Lobry D, Oh P, Cimmino L, Zhu N, et al. Notch pathway activation targets AML-initiating cell homeostasis and differentiation. J Exp Med. 2013;210:301-19 pubmed publisher |
Chang J, Burkett P, Borges C, Kuchroo V, Turka L, Chang C. MyD88 is essential to sustain mTOR activation necessary to promote T helper 17 cell proliferation by linking IL-1 and IL-23 signaling. Proc Natl Acad Sci U S A. 2013;110:2270-5 pubmed publisher |
Reardon C, Duncan G, Brüstle A, Brenner D, Tusche M, Olofsson P, et al. Lymphocyte-derived ACh regulates local innate but not adaptive immunity. Proc Natl Acad Sci U S A. 2013;110:1410-5 pubmed publisher |
Chen X, Wu X, Zhou Q, Howard O, Netea M, Oppenheim J. TNFR2 is critical for the stabilization of the CD4+Foxp3+ regulatory T. cell phenotype in the inflammatory environment. J Immunol. 2013;190:1076-84 pubmed publisher |
Jin H, Liao L, Park Y, Liu Y. Neddylation pathway regulates T-cell function by targeting an adaptor protein Shc and a protein kinase Erk signaling. Proc Natl Acad Sci U S A. 2013;110:624-9 pubmed publisher |
Huber M, Heink S, Pagenstecher A, Reinhard K, Ritter J, Visekruna A, et al. IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis. J Clin Invest. 2013;123:247-60 pubmed publisher |
Duncan G, Brenner D, Tusche M, Brüstle A, Knobbe C, Elia A, et al. 2-Methoxyestradiol inhibits experimental autoimmune encephalomyelitis through suppression of immune cell activation. Proc Natl Acad Sci U S A. 2012;109:21034-9 pubmed publisher |
Bian Z, Guo Y, Luo Y, Tremblay A, Zhang X, Dharma S, et al. CD47 deficiency does not impede polymorphonuclear neutrophil transmigration but attenuates granulopoiesis at the postacute stage of colitis. J Immunol. 2013;190:411-7 pubmed publisher |
Hamada H, Bassity E, Flies A, Strutt T, Garcia Hernandez M, McKinstry K, et al. Multiple redundant effector mechanisms of CD8+ T cells protect against influenza infection. J Immunol. 2013;190:296-306 pubmed publisher |
Zhang C, Li Y, Wu Y, Wang L, Wang X, Du J. Interleukin-6/signal transducer and activator of transcription 3 (STAT3) pathway is essential for macrophage infiltration and myoblast proliferation during muscle regeneration. J Biol Chem. 2013;288:1489-99 pubmed publisher |
Holoshitz J, Liu Y, Fu J, Joseph J, Ling S, Colletta A, et al. An HLA-DRB1-coded signal transduction ligand facilitates inflammatory arthritis: a new mechanism of autoimmunity. J Immunol. 2013;190:48-57 pubmed publisher |
Porter R, Georger M, Bromberg O, McGrath K, Frisch B, Becker M, et al. Prostaglandin E2 increases hematopoietic stem cell survival and accelerates hematopoietic recovery after radiation injury. Stem Cells. 2013;31:372-83 pubmed publisher |
Gruber T, Larson Gedman A, Zhang J, Koss C, Marada S, Ta H, et al. An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia. Cancer Cell. 2012;22:683-97 pubmed publisher |
Schoofs T, Rohde C, Hebestreit K, Klein H, Göllner S, Schulze I, et al. DNA methylation changes are a late event in acute promyelocytic leukemia and coincide with loss of transcription factor binding. Blood. 2013;121:178-87 pubmed publisher |
Gulen M, Bulek K, Xiao H, Yu M, Gao J, Sun L, et al. Inactivation of the enzyme GSK3? by the kinase IKKi promotes AKT-mTOR signaling pathway that mediates interleukin-1-induced Th17 cell maintenance. Immunity. 2012;37:800-12 pubmed publisher |
Brüstle A, Brenner D, Knobbe C, Lang P, Virtanen C, Hershenfield B, et al. The NF-?B regulator MALT1 determines the encephalitogenic potential of Th17 cells. J Clin Invest. 2012;122:4698-709 pubmed publisher |
Yao R, Ma Y, Liang W, Li H, Ma Z, Yu X, et al. MicroRNA-155 modulates Treg and Th17 cells differentiation and Th17 cell function by targeting SOCS1. PLoS ONE. 2012;7:e46082 pubmed publisher |
Perona Wright G, Kohlmeier J, Bassity E, Freitas T, Mohrs K, Cookenham T, et al. Persistent loss of IL-27 responsiveness in CD8+ memory T cells abrogates IL-10 expression in a recall response. Proc Natl Acad Sci U S A. 2012;109:18535-40 pubmed publisher |
Yi H, Guo C, Yu X, Zuo D, Wang X. Mouse CD11b+Gr-1+ myeloid cells can promote Th17 cell differentiation and experimental autoimmune encephalomyelitis. J Immunol. 2012;189:4295-304 pubmed publisher |
Nowak E, de Vries V, Wasiuk A, Ahonen C, Bennett K, Le Mercier I, et al. Tryptophan hydroxylase-1 regulates immune tolerance and inflammation. J Exp Med. 2012;209:2127-35 pubmed publisher |
Bauernfeind F, Rieger A, Schildberg F, Knolle P, Schmid Burgk J, Hornung V. NLRP3 inflammasome activity is negatively controlled by miR-223. J Immunol. 2012;189:4175-81 pubmed publisher |
Adhikary S, Kocieda V, Yen J, Tuma R, Ganea D. Signaling through cannabinoid receptor 2 suppresses murine dendritic cell migration by inhibiting matrix metalloproteinase 9 expression. Blood. 2012;120:3741-9 pubmed publisher |
Xu L, Sokalski K, Hotke K, Christie D, Zarnett O, Piskorz J, et al. Regulation of B cell linker protein transcription by PU.1 and Spi-B in murine B cell acute lymphoblastic leukemia. J Immunol. 2012;189:3347-54 pubmed |
Liu J, Hettmer S, Milsom M, Hofmann I, Hua F, Miller C, et al. Induction of histiocytic sarcoma in mouse skeletal muscle. PLoS ONE. 2012;7:e44044 pubmed publisher |
Lin D, Yin T, Koren Michowitz M, Ding L, Gueller S, Gery S, et al. Adaptor protein Lnk binds to and inhibits normal and leukemic FLT3. Blood. 2012;120:3310-7 pubmed publisher |
Zhang X, Han S, Kang Y, Guo M, Hong S, Liu F, et al. SAHA, an HDAC inhibitor, synergizes with tacrolimus to prevent murine cardiac allograft rejection. Cell Mol Immunol. 2012;9:390-8 pubmed publisher |
Cunningham L, Finckbeiner S, Hyde R, Southall N, Marugan J, Yedavalli V, et al. Identification of benzodiazepine Ro5-3335 as an inhibitor of CBF leukemia through quantitative high throughput screen against RUNX1-CBF? interaction. Proc Natl Acad Sci U S A. 2012;109:14592-7 pubmed publisher |
Peslak S, Wenger J, Bemis J, Kingsley P, Koniski A, McGrath K, et al. EPO-mediated expansion of late-stage erythroid progenitors in the bone marrow initiates recovery from sublethal radiation stress. Blood. 2012;120:2501-11 pubmed |
Arcipowski K, Bishop G. Roles of the kinase TAK1 in TRAF6-dependent signaling by CD40 and its oncogenic viral mimic, LMP1. PLoS ONE. 2012;7:e42478 pubmed publisher |
Hu P, Nebreda A, Liu Y, Carlesso N, Kaplan M, Kapur R. p38? protein negatively regulates T helper type 2 responses by orchestrating multiple T cell receptor-associated signals. J Biol Chem. 2012;287:33215-26 pubmed |
Yamaguchi T, Hamanaka S, Kamiya A, Okabe M, Kawarai M, Wakiyama Y, et al. Development of an all-in-one inducible lentiviral vector for gene specific analysis of reprogramming. PLoS ONE. 2012;7:e41007 pubmed publisher |
Zhi L, Ustyugova I, Chen X, Zhang Q, Wu M. Enhanced Th17 differentiation and aggravated arthritis in IEX-1-deficient mice by mitochondrial reactive oxygen species-mediated signaling. J Immunol. 2012;189:1639-47 pubmed publisher |
Poovassery J, Bishop G. Type I IFN receptor and the B cell antigen receptor regulate TLR7 responses via distinct molecular mechanisms. J Immunol. 2012;189:1757-64 pubmed publisher |
Sun K, Hsiao H, Li M, Ames E, Bouchlaka M, Welniak L, et al. IFN-? receptor-deficient donor T cells mediate protection from graft-versus-host disease and preserve graft-versus-tumor responses after allogeneic bone marrow transplantation. J Immunol. 2012;189:2033-42 pubmed publisher |
Asai T, Liu Y, Di Giandomenico S, Bae N, Ndiaye Lobry D, Deblasio A, et al. Necdin, a p53 target gene, regulates the quiescence and response to genotoxic stress of hematopoietic stem/progenitor cells. Blood. 2012;120:1601-12 pubmed publisher |
Cortes I, Sánchez Ruiz J, Zuluaga S, Calvanese V, Marqués M, Hernandez C, et al. p85? phosphoinositide 3-kinase subunit regulates tumor progression. Proc Natl Acad Sci U S A. 2012;109:11318-23 pubmed publisher |
Paiva C, Feijó D, Dutra F, Carneiro V, Freitas G, Alves L, et al. Oxidative stress fuels Trypanosoma cruzi infection in mice. J Clin Invest. 2012;122:2531-42 pubmed publisher |
Perry D, Yin Y, Telarico T, Baker H, Dozmorov I, Perl A, et al. Murine lupus susceptibility locus Sle1c2 mediates CD4+ T cell activation and maps to estrogen-related receptor ?. J Immunol. 2012;189:793-803 pubmed publisher |
Hubackova S, Krejcikova K, Bartek J, Hodny Z. Interleukin 6 signaling regulates promyelocytic leukemia protein gene expression in human normal and cancer cells. J Biol Chem. 2012;287:26702-14 pubmed publisher |
Yamada T, Park C, Burns A, Nakada D, Lacorazza H. The cytosolic protein G0S2 maintains quiescence in hematopoietic stem cells. PLoS ONE. 2012;7:e38280 pubmed publisher |
Pham D, Vincentz J, Firulli A, Kaplan M. Twist1 regulates Ifng expression in Th1 cells by interfering with Runx3 function. J Immunol. 2012;189:832-40 pubmed publisher |
Deng W, Lee J, Wang H, Miller J, Reik A, Gregory P, et al. Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor. Cell. 2012;149:1233-44 pubmed publisher |
Riewaldt J, D xfc ber S, Boernert M, Krey M, Dembinski M, Weiss S, et al. Severe Developmental B Lymphopoietic Defects in Foxp3-Deficient Mice are Refractory to Adoptive Regulatory T Cell Therapy. Front Immunol. 2012;3:141 pubmed publisher |
Cai M, Langer E, Gill J, Satpathy A, Albring J, Kc W, et al. Dual actions of Meis1 inhibit erythroid progenitor development and sustain general hematopoietic cell proliferation. Blood. 2012;120:335-46 pubmed publisher |
Tayabali A, Nguyen K, Shwed P, Crosthwait J, Coleman G, Seligy V. Comparison of the virulence potential of Acinetobacter strains from clinical and environmental sources. PLoS ONE. 2012;7:e37024 pubmed publisher |
Mukai K, Benbarak M, Tachibana M, Nishida K, Karasuyama H, Taniuchi I, et al. Critical role of P1-Runx1 in mouse basophil development. Blood. 2012;120:76-85 pubmed publisher |
Kwon M, Ma J, Ding Y, Wang R, Sun Z. Protein kinase C-? promotes Th17 differentiation via upregulation of Stat3. J Immunol. 2012;188:5887-97 pubmed publisher |
Ottina E, Grespi F, Tischner D, Soratroi C, Geley S, Ploner A, et al. Targeting antiapoptotic A1/Bfl-1 by in vivo RNAi reveals multiple roles in leukocyte development in mice. Blood. 2012;119:6032-42 pubmed publisher |
Abdi K, Singh N, Matzinger P. Lipopolysaccharide-activated dendritic cells: "exhausted" or alert and waiting?. J Immunol. 2012;188:5981-9 pubmed publisher |
Osterbur J, Sprague L, Muccioli M, Pate M, Mansfield K, McGinty J, et al. Adhesion to substrates induces dendritic cell endothelization and decreases immunological response. Immunobiology. 2013;218:64-75 pubmed publisher |
Eberle M, Dalpke A. Dectin-1 stimulation induces suppressor of cytokine signaling 1, thereby modulating TLR signaling and T cell responses. J Immunol. 2012;188:5644-54 pubmed publisher |
Jiang J, Balcerek J, Rozenova K, Cheng Y, Bersenev A, Wu C, et al. 14-3-3 regulates the LNK/JAK2 pathway in mouse hematopoietic stem and progenitor cells. J Clin Invest. 2012;122:2079-91 pubmed publisher |
Hashizume M, Yoshida H, Tanaka K, Suzuki M, Matsumoto I, Sumida T, et al. Interleukin-6 regulates anti-arthritic effect of methotrexate via reduction of SLC19A1 expression in a mouse arthritis model. Arthritis Res Ther. 2012;14:R96 pubmed publisher |
Ueda A, Zhou L, Stein P. Fyn promotes Th17 differentiation by regulating the kinetics of ROR?t and Foxp3 expression. J Immunol. 2012;188:5247-56 pubmed publisher |
Reddy P, Sargin B, Choudhary C, Stein S, Grez M, Muller Tidow C, et al. SOCS1 cooperates with FLT3-ITD in the development of myeloproliferative disease by promoting the escape from external cytokine control. Blood. 2012;120:1691-702 pubmed |
Mycko M, Cichalewska M, Machlanska A, Cwiklinska H, Mariasiewicz M, Selmaj K. MicroRNA-301a regulation of a T-helper 17 immune response controls autoimmune demyelination. Proc Natl Acad Sci U S A. 2012;109:E1248-57 pubmed publisher |
Lu H, Zhu S, Qian L, Xiang D, Zhang W, Nie A, et al. Activated expression of the chemokine Mig after chemotherapy contributes to chemotherapy-induced bone marrow suppression and lethal toxicity. Blood. 2012;119:4868-77 pubmed publisher |
Fares J, Koller R, Humeniuk R, Wolff L, Bies J. The tumor suppressor p15Ink4b regulates the differentiation and maturation of conventional dendritic cells. Blood. 2012;119:5005-15 pubmed publisher |
Guo H, Ma O, Speck N, Friedman A. Runx1 deletion or dominant inhibition reduces Cebpa transcription via conserved promoter and distal enhancer sites to favor monopoiesis over granulopoiesis. Blood. 2012;119:4408-18 pubmed publisher |
Ramon H, Beal A, Liu Y, Worthen G, Oliver P. The E3 ubiquitin ligase adaptor Ndfip1 regulates Th17 differentiation by limiting the production of proinflammatory cytokines. J Immunol. 2012;188:4023-31 pubmed publisher |
Spranger S, Jeremias I, Wilde S, Leisegang M, Stärck L, Mosetter B, et al. TCR-transgenic lymphocytes specific for HMMR/Rhamm limit tumor outgrowth in vivo. Blood. 2012;119:3440-9 pubmed publisher |
Poppensieker K, Otte D, Schürmann B, Limmer A, Dresing P, Drews E, et al. CC chemokine receptor 4 is required for experimental autoimmune encephalomyelitis by regulating GM-CSF and IL-23 production in dendritic cells. Proc Natl Acad Sci U S A. 2012;109:3897-902 pubmed publisher |
Cedeno Laurent F, Opperman M, Barthel S, Kuchroo V, Dimitroff C. Galectin-1 triggers an immunoregulatory signature in Th cells functionally defined by IL-10 expression. J Immunol. 2012;188:3127-37 pubmed publisher |
Greenblatt S, Li L, Slape C, Nguyen B, Novak R, Duffield A, et al. Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model. Blood. 2012;119:2883-94 pubmed publisher |
Gavrilescu L, Van Etten R. Murine retroviral bone marrow transplantation models for the study of human myeloproliferative disorders. Curr Protoc Pharmacol. 2008;Chapter 14:Unit14.10 pubmed publisher |
Block H, Herter J, Rossaint J, Stadtmann A, Kliche S, Lowell C, et al. Crucial role of SLP-76 and ADAP for neutrophil recruitment in mouse kidney ischemia-reperfusion injury. J Exp Med. 2012;209:407-21 pubmed publisher |
Newcomb D, Boswell M, Huckabee M, Goleniewska K, Dulek D, Reiss S, et al. IL-13 regulates Th17 secretion of IL-17A in an IL-10-dependent manner. J Immunol. 2012;188:1027-35 pubmed publisher |
Yuan H, Wang Z, Li L, Zhang H, Modi H, Horne D, et al. Activation of stress response gene SIRT1 by BCR-ABL promotes leukemogenesis. Blood. 2012;119:1904-14 pubmed publisher |
Yiakouvaki A, Dimitriou M, Karakasiliotis I, Eftychi C, Theocharis S, Kontoyiannis D. Myeloid cell expression of the RNA-binding protein HuR protects mice from pathologic inflammation and colorectal carcinogenesis. J Clin Invest. 2012;122:48-61 pubmed publisher |
Siggs O, Li X, Xia Y, Beutler B. ZBTB1 is a determinant of lymphoid development. J Exp Med. 2012;209:19-27 pubmed publisher |
Purtha W, Tedder T, Johnson S, Bhattacharya D, Diamond M. Memory B cells, but not long-lived plasma cells, possess antigen specificities for viral escape mutants. J Exp Med. 2011;208:2599-606 pubmed publisher |
Zhao L, Melenhorst J, Alemu L, Kirby M, Anderson S, Kench M, et al. KIT with D816 mutations cooperates with CBFB-MYH11 for leukemogenesis in mice. Blood. 2012;119:1511-21 pubmed publisher |
Mir S, Chatterjee A, Mitra A, Pathak K, Mahata S, Sarkar S. Inhibition of signal transducer and activator of transcription 3 (STAT3) attenuates interleukin-6 (IL-6)-induced collagen synthesis and resultant hypertrophy in rat heart. J Biol Chem. 2012;287:2666-77 pubmed publisher |
Bian Z, Guo Y, Ha B, Zen K, Liu Y. Regulation of the inflammatory response: enhancing neutrophil infiltration under chronic inflammatory conditions. J Immunol. 2012;188:844-53 pubmed publisher |
Panzer M, Sitte S, Wirth S, Drexler I, Sparwasser T, Voehringer D. Rapid in vivo conversion of effector T cells into Th2 cells during helminth infection. J Immunol. 2012;188:615-23 pubmed publisher |
Schoppy D, Ragland R, Gilad O, Shastri N, Peters A, Murga M, et al. Oncogenic stress sensitizes murine cancers to hypomorphic suppression of ATR. J Clin Invest. 2012;122:241-52 pubmed publisher |
Shen S, Manser T. Direct reduction of antigen receptor expression in polyclonal B cell populations developing in vivo results in light chain receptor editing. J Immunol. 2012;188:47-56 pubmed publisher |
Mou Y, Hou Y, Chen B, Hua Z, Zhang Y, Xie H, et al. In vivo migration of dendritic cells labeled with synthetic superparamagnetic iron oxide. Int J Nanomedicine. 2011;6:2633-40 pubmed publisher |
Dong X, Feng P. Murine gamma herpesvirus 68 hijacks MAVS and IKK? to abrogate NF?B activation and antiviral cytokine production. PLoS Pathog. 2011;7:e1002336 pubmed publisher |
Reynaud D, Pietras E, Barry Holson K, Mir A, Binnewies M, Jeanne M, et al. IL-6 controls leukemic multipotent progenitor cell fate and contributes to chronic myelogenous leukemia development. Cancer Cell. 2011;20:661-73 pubmed publisher |
Baschant U, Frappart L, Rauchhaus U, Bruns L, Reichardt H, Kamradt T, et al. Glucocorticoid therapy of antigen-induced arthritis depends on the dimerized glucocorticoid receptor in T cells. Proc Natl Acad Sci U S A. 2011;108:19317-22 pubmed publisher |
LaCasse C, Janikashvili N, Larmonier C, Alizadeh D, Hanke N, Kartchner J, et al. Th-1 lymphocytes induce dendritic cell tumor killing activity by an IFN-?-dependent mechanism. J Immunol. 2011;187:6310-7 pubmed publisher |
Dagälv A, Holmborn K, Kjellen L, Abrink M. Lowered expression of heparan sulfate/heparin biosynthesis enzyme N-deacetylase/n-sulfotransferase 1 results in increased sulfation of mast cell heparin. J Biol Chem. 2011;286:44433-40 pubmed publisher |
Iguchi Hashimoto M, Usui T, Yoshifuji H, Shimizu M, Kobayashi S, Ito Y, et al. Overexpression of a minimal domain of calpastatin suppresses IL-6 production and Th17 development via reduced NF-?B and increased STAT5 signals. PLoS ONE. 2011;6:e27020 pubmed publisher |
Lu K, Kanno Y, Cannons J, Handon R, Bible P, Elkahloun A, et al. Functional and epigenetic studies reveal multistep differentiation and plasticity of in vitro-generated and in vivo-derived follicular T helper cells. Immunity. 2011;35:622-32 pubmed publisher |
Ghiani C, Mattan N, Nobuta H, Malvar J, Boles J, Ross M, et al. Early effects of lipopolysaccharide-induced inflammation on foetal brain development in rat. ASN Neuro. 2011;3: pubmed publisher |
Chang S, Reynolds J, Pappu B, Chen G, Martinez G, Dong C. Interleukin-17C promotes Th17 cell responses and autoimmune disease via interleukin-17 receptor E. Immunity. 2011;35:611-21 pubmed publisher |
Mou Y, Chen B, Zhang Y, Hou Y, Xie H, Xia G, et al. Influence of synthetic superparamagnetic iron oxide on dendritic cells. Int J Nanomedicine. 2011;6:1779-86 pubmed publisher |
Nakagawa R, Yoshida H, Asakawa M, Tamiya T, Inoue N, Morita R, et al. Pyridone 6, a pan-JAK inhibitor, ameliorates allergic skin inflammation of NC/Nga mice via suppression of Th2 and enhancement of Th17. J Immunol. 2011;187:4611-20 pubmed publisher |
Cooney L, Towery K, Endres J, Fox D. Sensitivity and resistance to regulation by IL-4 during Th17 maturation. J Immunol. 2011;187:4440-50 pubmed publisher |
Kim S, Zou Y, Goldstein J, Reizis B, Diamond B. Tolerogenic function of Blimp-1 in dendritic cells. J Exp Med. 2011;208:2193-9 pubmed publisher |
Ma J, Wang R, Fang X, Ding Y, Sun Z. Critical role of TCF-1 in repression of the IL-17 gene. PLoS ONE. 2011;6:e24768 pubmed publisher |
Ye F, Han L, Lu Q, Dong W, Chen Z, Shao H, et al. Retinal self-antigen induces a predominantly Th1 effector response in Axl and Mertk double-knockout mice. J Immunol. 2011;187:4178-86 pubmed publisher |
Li N, Matte Martone C, Zheng H, Cui W, Venkatesan S, Tan H, et al. Memory T cells from minor histocompatibility antigen-vaccinated and virus-immune donors improve GVL and immune reconstitution. Blood. 2011;118:5965-76 pubmed publisher |
Hurtz C, Hatzi K, Cerchietti L, Braig M, Park E, Kim Y, et al. BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia. J Exp Med. 2011;208:2163-74 pubmed publisher |
Mali R, Ramdas B, Ma P, Shi J, Munugalavadla V, Sims E, et al. Rho kinase regulates the survival and transformation of cells bearing oncogenic forms of KIT, FLT3, and BCR-ABL. Cancer Cell. 2011;20:357-69 pubmed publisher |
Hahn J, Falck V, Jirik F. Smad4 deficiency in T cells leads to the Th17-associated development of premalignant gastroduodenal lesions in mice. J Clin Invest. 2011;121:4030-42 pubmed publisher |
Aue G, Du Y, Cleveland S, Smith S, DAVE U, Liu D, et al. Sox4 cooperates with PU.1 haploinsufficiency in murine myeloid leukemia. Blood. 2011;118:4674-81 pubmed publisher |
Dang E, Barbi J, Yang H, Jinasena D, Yu H, Zheng Y, et al. Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1. Cell. 2011;146:772-84 pubmed publisher |
Van Belle T, Esplugues E, Liao J, Juntti T, Flavell R, Von Herrath M. Development of autoimmune diabetes in the absence of detectable IL-17A in a CD8-driven virally induced model. J Immunol. 2011;187:2915-22 pubmed publisher |
Chi A, Chavez A, Xu L, Weber B, Shestova O, Schaffer A, et al. Identification of Flt3?CD150? myeloid progenitors in adult mouse bone marrow that harbor T lymphoid developmental potential. Blood. 2011;118:2723-32 pubmed publisher |
Persson J, Beyer I, Yumul R, Li Z, Kiem H, Roffler S, et al. Immuno-therapy with anti-CTLA4 antibodies in tolerized and non-tolerized mouse tumor models. PLoS ONE. 2011;6:e22303 pubmed publisher |
Matte Martone C, Venkatesan S, Tan H, Athanasiadis I, Chang J, Pavisic J, et al. Graft-versus-leukemia (GVL) against mouse blast-crisis chronic myelogenous leukemia (BC-CML) and chronic-phase chronic myelogenous leukemia (CP-CML): shared mechanisms of T cell killing, but programmed death ligands render CP-CML and not BC-CML GVL r. J Immunol. 2011;187:1653-63 pubmed publisher |
Ghani S, Riemke P, Schönheit J, Lenze D, Stumm J, Hoogenkamp M, et al. Macrophage development from HSCs requires PU.1-coordinated microRNA expression. Blood. 2011;118:2275-84 pubmed publisher |
Cantor J, Slepak M, Ege N, Chang J, Ginsberg M. Loss of T cell CD98 H chain specifically ablates T cell clonal expansion and protects from autoimmunity. J Immunol. 2011;187:851-60 pubmed publisher |
Knosp C, Carroll H, Elliott J, Saunders S, Nel H, Amu S, et al. SOCS2 regulates T helper type 2 differentiation and the generation of type 2 allergic responses. J Exp Med. 2011;208:1523-31 pubmed publisher |
Sprague L, Muccioli M, Pate M, Meles E, McGinty J, Nandigam H, et al. The interplay between surfaces and soluble factors define the immunologic and angiogenic properties of myeloid dendritic cells. BMC Immunol. 2011;12:35 pubmed publisher |
Ishizaki M, Akimoto T, Muromoto R, Yokoyama M, Ohshiro Y, Sekine Y, et al. Involvement of tyrosine kinase-2 in both the IL-12/Th1 and IL-23/Th17 axes in vivo. J Immunol. 2011;187:181-9 pubmed publisher |
Sander L, Davis M, Boekschoten M, Amsen D, Dascher C, Ryffel B, et al. Detection of prokaryotic mRNA signifies microbial viability and promotes immunity. Nature. 2011;474:385-9 pubmed publisher |
Ehlting C, Ronkina N, Böhmer O, Albrecht U, Bode K, Lang K, et al. Distinct functions of the mitogen-activated protein kinase-activated protein (MAPKAP) kinases MK2 and MK3: MK2 mediates lipopolysaccharide-induced signal transducers and activators of transcription 3 (STAT3) activation by preventing negative regulato. J Biol Chem. 2011;286:24113-24 pubmed publisher |
Bard Chapeau E, Li S, Ding J, Zhang S, Zhu H, Princen F, et al. Ptpn11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesis. Cancer Cell. 2011;19:629-39 pubmed publisher |
Heinonen K, Vanegas J, Lew D, Krosl J, Perreault C. Wnt4 enhances murine hematopoietic progenitor cell expansion through a planar cell polarity-like pathway. PLoS ONE. 2011;6:e19279 pubmed publisher |
Nguyen A, Taranova O, He J, Zhang Y. DOT1L, the H3K79 methyltransferase, is required for MLL-AF9-mediated leukemogenesis. Blood. 2011;117:6912-22 pubmed publisher |
Liu Z, Yang A, Wang Z, Bunting K, Davuluri G, Green M, et al. Multiple apoptotic defects in hematopoietic cells from mice lacking lipocalin 24p3. J Biol Chem. 2011;286:20606-14 pubmed publisher |
Capurso N, Look M, Jeanbart L, Nowyhed H, Abraham C, Craft J, et al. Development of a nanoparticulate formulation of retinoic acid that suppresses Th17 cells and upregulates regulatory T cells. Self Nonself. 2010;1:335-340 pubmed |
Chen Z, Phillips L, Gould E, Campisi J, Lee S, Ormerod B, et al. MHC mismatch inhibits neurogenesis and neuron maturation in stem cell allografts. PLoS ONE. 2011;6:e14787 pubmed publisher |
Peng D, Zeng M, Muromoto R, Matsuda T, Shimoda K, Subramaniam M, et al. Noncanonical K27-linked polyubiquitination of TIEG1 regulates Foxp3 expression and tumor growth. J Immunol. 2011;186:5638-47 pubmed publisher |
Stock A, Booth S, Cerundolo V. Prostaglandin E2 suppresses the differentiation of retinoic acid-producing dendritic cells in mice and humans. J Exp Med. 2011;208:761-73 pubmed publisher |
Negre O, Fusil F, Colomb C, Roth S, Gillet Legrand B, Henri A, et al. Correction of murine β-thalassemia after minimal lentiviral gene transfer and homeostatic in vivo erythroid expansion. Blood. 2011;117:5321-31 pubmed publisher |
Eto D, LAO C, DiToro D, Barnett B, Escobar T, Kageyama R, et al. IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (Tfh) differentiation. PLoS ONE. 2011;6:e17739 pubmed publisher |
Molinero L, Miller M, Evaristo C, Alegre M. High TCR stimuli prevent induced regulatory T cell differentiation in a NF-?B-dependent manner. J Immunol. 2011;186:4609-17 pubmed publisher |
Sehra S, Yao W, Nguyen E, Ahyi A, Tuana F, Ahlfeld S, et al. Periostin regulates goblet cell metaplasia in a model of allergic airway inflammation. J Immunol. 2011;186:4959-66 pubmed publisher |
Zhu Y, Gumlaw N, Karman J, Zhao H, Zhang J, Jiang J, et al. Lowering glycosphingolipid levels in CD4+ T cells attenuates T cell receptor signaling, cytokine production, and differentiation to the Th17 lineage. J Biol Chem. 2011;286:14787-94 pubmed publisher |
Yang J, Yang X, Chu Y, Li M. Identification of Baicalin as an immunoregulatory compound by controlling T(H)17 cell differentiation. PLoS ONE. 2011;6:e17164 pubmed publisher |
Kitajima K, Minehata K, Sakimura K, Nakano T, Hara T. In vitro generation of HSC-like cells from murine ESCs/iPSCs by enforced expression of LIM-homeobox transcription factor Lhx2. Blood. 2011;117:3748-58 pubmed publisher |
Bending D, Newland S, Krejci A, Phillips J, Bray S, Cooke A. Epigenetic changes at Il12rb2 and Tbx21 in relation to plasticity behavior of Th17 cells. J Immunol. 2011;186:3373-82 pubmed publisher |
Singh V, Jain S, Gowthaman U, Parihar P, Gupta P, Gupta U, et al. Co-administration of IL-1+IL-6+TNF-? with Mycobacterium tuberculosis infected macrophages vaccine induces better protective T cell memory than BCG. PLoS ONE. 2011;6:e16097 pubmed publisher |
Suzuki T, Imai J, Yamada T, Ishigaki Y, Kaneko K, Uno K, et al. Interleukin-6 enhances glucose-stimulated insulin secretion from pancreatic beta-cells: potential involvement of the PLC-IP3-dependent pathway. Diabetes. 2011;60:537-47 pubmed publisher |
Sumpter T, Packiam V, Turnquist H, Castellaneta A, Yoshida O, Thomson A. DAP12 promotes IRAK-M expression and IL-10 production by liver myeloid dendritic cells and restrains their T cell allostimulatory ability. J Immunol. 2011;186:1970-80 pubmed publisher |
Takeuchi H, Yokota A, Ohoka Y, Iwata M. Cyp26b1 regulates retinoic acid-dependent signals in T cells and its expression is inhibited by transforming growth factor-?. PLoS ONE. 2011;6:e16089 pubmed publisher |
Steffen B, Knop M, Bergholz U, Vakhrusheva O, Rode M, Kohler G, et al. AML1/ETO induces self-renewal in hematopoietic progenitor cells via the Groucho-related amino-terminal AES protein. Blood. 2011;117:4328-37 pubmed publisher |
Stritesky G, Muthukrishnan R, Sehra S, Goswami R, Pham D, Travers J, et al. The transcription factor STAT3 is required for T helper 2 cell development. Immunity. 2011;34:39-49 pubmed publisher |
Domingues H, Mues M, Lassmann H, Wekerle H, Krishnamoorthy G. Functional and pathogenic differences of Th1 and Th17 cells in experimental autoimmune encephalomyelitis. PLoS ONE. 2010;5:e15531 pubmed publisher |
Garrison S, Thornton J, Hacker H, Webby R, Rehg J, Parganas E, et al. The p53-target gene puma drives neutrophil-mediated protection against lethal bacterial sepsis. PLoS Pathog. 2010;6:e1001240 pubmed publisher |
Beurel E, Yeh W, Michalek S, Harrington L, Jope R. Glycogen synthase kinase-3 is an early determinant in the differentiation of pathogenic Th17 cells. J Immunol. 2011;186:1391-8 pubmed publisher |
Welch J, Klco J, Varghese N, Nagarajan R, Ley T. Rara haploinsufficiency modestly influences the phenotype of acute promyelocytic leukemia in mice. Blood. 2011;117:2460-8 pubmed publisher |
Flygare J, Rayon Estrada V, Shin C, Gupta S, Lodish H. HIF1alpha synergizes with glucocorticoids to promote BFU-E progenitor self-renewal. Blood. 2011;117:3435-44 pubmed publisher |
Doisne J, Soulard V, Becourt C, Amniai L, Henrot P, Havenar Daughton C, et al. Cutting edge: crucial role of IL-1 and IL-23 in the innate IL-17 response of peripheral lymph node NK1.1- invariant NKT cells to bacteria. J Immunol. 2011;186:662-6 pubmed publisher |
Richie Ehrlich L, Serwold T, Weissman I. In vitro assays misrepresent in vivo lineage potentials of murine lymphoid progenitors. Blood. 2011;117:2618-24 pubmed publisher |
Kreisel D, Sugimoto S, Tietjens J, Zhu J, Yamamoto S, Krupnick A, et al. Bcl3 prevents acute inflammatory lung injury in mice by restraining emergency granulopoiesis. J Clin Invest. 2011;121:265-76 pubmed publisher |
Yeung J, Esposito M, Gandillet A, Zeisig B, Griessinger E, Bonnet D, et al. ?-Catenin mediates the establishment and drug resistance of MLL leukemic stem cells. Cancer Cell. 2010;18:606-18 pubmed publisher |
Grenningloh R, Tai T, Frahm N, Hongo T, Chicoine A, Brander C, et al. Ets-1 maintains IL-7 receptor expression in peripheral T cells. J Immunol. 2011;186:969-76 pubmed publisher |
Thaler R, Agsten M, Spitzer S, Paschalis E, Karlic H, Klaushofer K, et al. Homocysteine suppresses the expression of the collagen cross-linker lysyl oxidase involving IL-6, Fli1, and epigenetic DNA methylation. J Biol Chem. 2011;286:5578-88 pubmed publisher |
Nakada D, Saunders T, Morrison S. Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells. Nature. 2010;468:653-8 pubmed publisher |
Giroux M, Delisle J, Gauthier S, Heinonen K, Hinsinger J, Houde B, et al. SMAD3 prevents graft-versus-host disease by restraining Th1 differentiation and granulocyte-mediated tissue damage. Blood. 2011;117:1734-44 pubmed publisher |
Melton A, Bailey Bucktrout S, Travis M, Fife B, Bluestone J, Sheppard D. Expression of ?v?8 integrin on dendritic cells regulates Th17 cell development and experimental autoimmune encephalomyelitis in mice. J Clin Invest. 2010;120:4436-44 pubmed publisher |
Sun X, Yamada H, Shibata K, Muta H, Tani K, Podack E, et al. CD30 ligand is a target for a novel biological therapy against colitis associated with Th17 responses. J Immunol. 2010;185:7671-80 pubmed publisher |
Guo H, Friedman A. Phosphorylation of RUNX1 by cyclin-dependent kinase reduces direct interaction with HDAC1 and HDAC3. J Biol Chem. 2011;286:208-15 pubmed publisher |
Seike T, Fujita K, Yamakawa Y, Kido M, Takiguchi S, Teramoto N, et al. Interaction between lung cancer cells and astrocytes via specific inflammatory cytokines in the microenvironment of brain metastasis. Clin Exp Metastasis. 2011;28:13-25 pubmed publisher |
Kastner L, Dwyer D, Qin F. Synergistic effect of IL-6 and IL-4 in driving fate revision of natural Foxp3+ regulatory T cells. J Immunol. 2010;185:5778-86 pubmed publisher |
Wang Y, Voo K, Liu B, Chen C, Uygungil B, Spoede W, et al. A novel subset of CD4(+) T(H)2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma. J Exp Med. 2010;207:2479-91 pubmed publisher |
Rolf J, Bell S, Kovesdi D, Janas M, Soond D, Webb L, et al. Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction. J Immunol. 2010;185:4042-52 pubmed publisher |
Keeshan K, Bailis W, Dedhia P, Vega M, Shestova O, Xu L, et al. Transformation by Tribbles homolog 2 (Trib2) requires both the Trib2 kinase domain and COP1 binding. Blood. 2010;116:4948-57 pubmed publisher |
Ji H, Ehrlich L, Seita J, Murakami P, Doi A, Lindau P, et al. Comprehensive methylome map of lineage commitment from haematopoietic progenitors. Nature. 2010;467:338-42 pubmed publisher |
Kitamura K, Farber J, Kelsall B. CCR6 marks regulatory T cells as a colon-tropic, IL-10-producing phenotype. J Immunol. 2010;185:3295-304 pubmed publisher |
Ragu C, Elain G, Mylonas E, Ottolenghi C, Cagnard N, Daegelen D, et al. The transcription factor Srf regulates hematopoietic stem cell adhesion. Blood. 2010;116:4464-73 pubmed publisher |
Biswas P, Gupta S, Chang E, Song L, Stirzaker R, Liao J, et al. Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice. J Clin Invest. 2010;120:3280-95 pubmed publisher |
Li X, Koh A, Wang Z, Soki F, Park S, Pienta K, et al. Inhibitory effects of megakaryocytic cells in prostate cancer skeletal metastasis. J Bone Miner Res. 2011;26:125-34 pubmed publisher |
Vemula S, Ramdas B, Hanneman P, Martin J, Beggs H, Kapur R. Essential role for focal adhesion kinase in regulating stress hematopoiesis. Blood. 2010;116:4103-15 pubmed publisher |
Kashiwakuma D, Suto A, Hiramatsu Y, Ikeda K, Takatori H, Suzuki K, et al. B and T lymphocyte attenuator suppresses IL-21 production from follicular Th cells and subsequent humoral immune responses. J Immunol. 2010;185:2730-6 pubmed publisher |
Malhotra N, Robertson E, Kang J. SMAD2 is essential for TGF beta-mediated Th17 cell generation. J Biol Chem. 2010;285:29044-8 pubmed publisher |
Sun X, Yamada H, Shibata K, Muta H, Tani K, Podack E, et al. CD30 ligand/CD30 plays a critical role in Th17 differentiation in mice. J Immunol. 2010;185:2222-30 pubmed publisher |
Adams C, Housley W, Bhowmick S, Cone R, Rajan T, Forouhar F, et al. Cbl-b(-/-) T cells demonstrate in vivo resistance to regulatory T cells but a context-dependent resistance to TGF-beta. J Immunol. 2010;185:2051-8 pubmed publisher |
Ying H, Yang L, Qiao G, Li Z, Zhang L, Yin F, et al. Cutting edge: CTLA-4--B7 interaction suppresses Th17 cell differentiation. J Immunol. 2010;185:1375-8 pubmed publisher |
de Almeida D, Ling S, Pi X, Hartmann Scruggs A, Pumpens P, Holoshitz J. Immune dysregulation by the rheumatoid arthritis shared epitope. J Immunol. 2010;185:1927-34 pubmed publisher |
Schallenberg S, Tsai P, Riewaldt J, Kretschmer K. Identification of an immediate Foxp3(-) precursor to Foxp3(+) regulatory T cells in peripheral lymphoid organs of nonmanipulated mice. J Exp Med. 2010;207:1393-407 pubmed publisher |
Wang G, Miyahara Y, Guo Z, Khattar M, Stepkowski S, Chen W. "Default" generation of neonatal regulatory T cells. J Immunol. 2010;185:71-8 pubmed publisher |
Wang Z, Rhee D, Lu J, Bohr C, Zhou F, Vallabhaneni H, et al. Characterization of oxidative guanine damage and repair in mammalian telomeres. PLoS Genet. 2010;6:e1000951 pubmed publisher |
Bersenev A, Wu C, Balcerek J, Jing J, Kundu M, Blobel G, et al. Lnk constrains myeloproliferative diseases in mice. J Clin Invest. 2010;120:2058-69 pubmed publisher |
Dedhia P, Keeshan K, ULJON S, Xu L, Vega M, Shestova O, et al. Differential ability of Tribbles family members to promote degradation of C/EBPalpha and induce acute myelogenous leukemia. Blood. 2010;116:1321-8 pubmed publisher |
Wang C, Kang S, HogenEsch H, Love P, Kim C. Retinoic acid determines the precise tissue tropism of inflammatory Th17 cells in the intestine. J Immunol. 2010;184:5519-26 pubmed publisher |
Chou S, Lodish H. Fetal liver hepatic progenitors are supportive stromal cells for hematopoietic stem cells. Proc Natl Acad Sci U S A. 2010;107:7799-804 pubmed publisher |
Okamoto K, Iwai Y, Oh Hora M, Yamamoto M, Morio T, Aoki K, et al. IkappaBzeta regulates T(H)17 development by cooperating with ROR nuclear receptors. Nature. 2010;464:1381-5 pubmed publisher |
Juntilla M, Patil V, Calamito M, Joshi R, Birnbaum M, Koretzky G. AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species. Blood. 2010;115:4030-8 pubmed publisher |
Cejas P, Walsh M, Pearce E, Han D, Harms G, Artis D, et al. TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2. Blood. 2010;115:4750-7 pubmed publisher |
Xynos A, Corbella P, Belmonte N, Zini R, Manfredini R, Ferrari G. Bone marrow-derived hematopoietic cells undergo myogenic differentiation following a Pax-7 independent pathway. Stem Cells. 2010;28:965-73 pubmed publisher |
Henderson R, Grys K, Vehlow A, de Bettignies C, Zachacz A, Henley T, et al. A novel Rac-dependent checkpoint in B cell development controls entry into the splenic white pulp and cell survival. J Exp Med. 2010;207:837-53 pubmed publisher |
Hall L, Clare S, Dougan G. NK cells influence both innate and adaptive immune responses after mucosal immunization with antigen and mucosal adjuvant. J Immunol. 2010;184:4327-37 pubmed publisher |
Agrawal Singh S, Koschmieder S, Gelsing S, Stocking C, Stehling M, Thiede C, et al. Pim2 cooperates with PML-RARalpha to induce acute myeloid leukemia in a bone marrow transplantation model. Blood. 2010;115:4507-16 pubmed publisher |
Urbieta M, Barao I, Jones M, Jurecic R, Panoskaltsis Mortari A, Blazar B, et al. Hematopoietic progenitor cell regulation by CD4+CD25+ T cells. Blood. 2010;115:4934-43 pubmed publisher |
Yen J, Kong W, Ganea D. IFN-beta inhibits dendritic cell migration through STAT-1-mediated transcriptional suppression of CCR7 and matrix metalloproteinase 9. J Immunol. 2010;184:3478-86 pubmed publisher |
Tartar D, Vanmorlan A, Wan X, Guloglu F, Jain R, Haymaker C, et al. FoxP3+RORgammat+ T helper intermediates display suppressive function against autoimmune diabetes. J Immunol. 2010;184:3377-85 pubmed publisher |
Bach C, Buhl S, Mueller D, Garcia Cuellar M, Maethner E, Slany R. Leukemogenic transformation by HOXA cluster genes. Blood. 2010;115:2910-8 pubmed publisher |
Kong W, Yen J, Vassiliou E, Adhikary S, Toscano M, Ganea D. Docosahexaenoic acid prevents dendritic cell maturation and in vitro and in vivo expression of the IL-12 cytokine family. Lipids Health Dis. 2010;9:12 pubmed publisher |
Zhou Z, French D, Ma G, Eisenstein S, Chen Y, Divino C, et al. Development and function of myeloid-derived suppressor cells generated from mouse embryonic and hematopoietic stem cells. Stem Cells. 2010;28:620-32 pubmed publisher |
Gregory G, Miccio A, Bersenev A, Wang Y, Hong W, Zhang Z, et al. FOG1 requires NuRD to promote hematopoiesis and maintain lineage fidelity within the megakaryocytic-erythroid compartment. Blood. 2010;115:2156-66 pubmed publisher |
Desvignes L, Ernst J. Interferon-gamma-responsive nonhematopoietic cells regulate the immune response to Mycobacterium tuberculosis. Immunity. 2009;31:974-85 pubmed publisher |
Gulen M, Kang Z, Bulek K, Youzhong W, Kim T, Chen Y, et al. The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation. Immunity. 2010;32:54-66 pubmed publisher |
Kovacic J, Gupta R, Lee A, Ma M, Fang F, Tolbert C, et al. Stat3-dependent acute Rantes production in vascular smooth muscle cells modulates inflammation following arterial injury in mice. J Clin Invest. 2010;120:303-14 pubmed publisher |
Li G, Miskimen K, Wang Z, Xie X, Brenzovich J, Ryan J, et al. STAT5 requires the N-domain for suppression of miR15/16, induction of bcl-2, and survival signaling in myeloproliferative disease. Blood. 2010;115:1416-24 pubmed publisher |
Qiu J, Lu X, Zeisig B, Ma Z, Cai X, Chen S, et al. Leukemic transformation by the APL fusion protein PRKAR1A-RAR{alpha} critically depends on recruitment of RXR{alpha}. Blood. 2010;115:643-52 pubmed publisher |
Mueller D, Garcia Cuellar M, Bach C, Buhl S, Maethner E, Slany R. Misguided transcriptional elongation causes mixed lineage leukemia. PLoS Biol. 2009;7:e1000249 pubmed publisher |
Aguilar S, Scotton C, McNulty K, Nye E, Stamp G, Laurent G, et al. Bone marrow stem cells expressing keratinocyte growth factor via an inducible lentivirus protects against bleomycin-induced pulmonary fibrosis. PLoS ONE. 2009;4:e8013 pubmed publisher |
Wrzesinski C, Paulos C, Kaiser A, Muranski P, Palmer D, Gattinoni L, et al. Increased intensity lymphodepletion enhances tumor treatment efficacy of adoptively transferred tumor-specific T cells. J Immunother. 2010;33:1-7 pubmed publisher |
Schmaier A, Zou Z, Kazlauskas A, Emert Sedlak L, Fong K, Neeves K, et al. Molecular priming of Lyn by GPVI enables an immune receptor to adopt a hemostatic role. Proc Natl Acad Sci U S A. 2009;106:21167-72 pubmed publisher |
Crabé S, Guay Giroux A, Tormo A, Duluc D, Lissilaa R, Guilhot F, et al. The IL-27 p28 subunit binds cytokine-like factor 1 to form a cytokine regulating NK and T cell activities requiring IL-6R for signaling. J Immunol. 2009;183:7692-702 pubmed publisher |
Oyamada A, Ikebe H, Itsumi M, Saiwai H, Okada S, Shimoda K, et al. Tyrosine kinase 2 plays critical roles in the pathogenic CD4 T cell responses for the development of experimental autoimmune encephalomyelitis. J Immunol. 2009;183:7539-46 pubmed publisher |
Canonigo Balancio A, Fos C, Prod homme T, Bécart S, Altman A. SLAT/Def6 plays a critical role in the development of Th17 cell-mediated experimental autoimmune encephalomyelitis. J Immunol. 2009;183:7259-67 pubmed publisher |
Yanai H, Ban T, Wang Z, Choi M, Kawamura T, Negishi H, et al. HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses. Nature. 2009;462:99-103 pubmed publisher |
Tanaka S, Yoshimoto T, Naka T, Nakae S, Iwakura Y, Cua D, et al. Natural occurring IL-17 producing T cells regulate the initial phase of neutrophil mediated airway responses. J Immunol. 2009;183:7523-30 pubmed publisher |
Martinez G, Zhang Z, Chung Y, Reynolds J, Lin X, Jetten A, et al. Smad3 differentially regulates the induction of regulatory and inflammatory T cell differentiation. J Biol Chem. 2009;284:35283-6 pubmed publisher |
Liu Z, Li Z, Mao K, Zou J, Wang Y, Tao Z, et al. Dec2 promotes Th2 cell differentiation by enhancing IL-2R signaling. J Immunol. 2009;183:6320-9 pubmed publisher |
Rice K, Hormaeche I, Doulatov S, Flatow J, Grimwade D, Mills K, et al. Comprehensive genomic screens identify a role for PLZF-RARalpha as a positive regulator of cell proliferation via direct regulation of c-MYC. Blood. 2009;114:5499-511 pubmed publisher |
Johnson K, Griswold I, O Hare T, Corbin A, Loriaux M, Deininger M, et al. A BCR-ABL mutant lacking direct binding sites for the GRB2, CBL and CRKL adapter proteins fails to induce leukemia in mice. PLoS ONE. 2009;4:e7439 pubmed publisher |
Gomez Rodriguez J, Sahu N, Handon R, Davidson T, Anderson S, Kirby M, et al. Differential expression of interleukin-17A and -17F is coupled to T cell receptor signaling via inducible T cell kinase. Immunity. 2009;31:587-97 pubmed publisher |
Xu H, Eleswarapu S, Geiger H, Szczur K, Daria D, Zheng Y, et al. Loss of the Rho GTPase activating protein p190-B enhances hematopoietic stem cell engraftment potential. Blood. 2009;114:3557-66 pubmed publisher |
Miletic A, Graham D, Sakata Sogawa K, Hiroshima M, Hamann M, Cemerski S, et al. Vav links the T cell antigen receptor to the actin cytoskeleton and T cell activation independently of intrinsic Guanine nucleotide exchange activity. PLoS ONE. 2009;4:e6599 pubmed publisher |
Kim S, Shen T, Min B. Basophils can directly present or cross-present antigen to CD8 lymphocytes and alter CD8 T cell differentiation into IL-10-producing phenotypes. J Immunol. 2009;183:3033-9 pubmed publisher |
Hu X, Shen H, Tian C, Yu H, Zheng G, XuFeng R, et al. Kinetics of normal hematopoietic stem and progenitor cells in a Notch1-induced leukemia model. Blood. 2009;114:3783-92 pubmed publisher |
Poovassery J, Vanden Bush T, Bishop G. Antigen receptor signals rescue B cells from TLR tolerance. J Immunol. 2009;183:2974-83 pubmed publisher |
Piconese S, Gri G, Tripodo C, Musio S, Gorzanelli A, Frossi B, et al. Mast cells counteract regulatory T-cell suppression through interleukin-6 and OX40/OX40L axis toward Th17-cell differentiation. Blood. 2009;114:2639-48 pubmed publisher |
Zhao L, Dong H, Zhang C, Kinch L, Osawa M, Iacovino M, et al. A JAK2 interdomain linker relays Epo receptor engagement signals to kinase activation. J Biol Chem. 2009;284:26988-98 pubmed publisher |
Aleyas A, George J, Han Y, Rahman M, Kim S, Han S, et al. Functional modulation of dendritic cells and macrophages by Japanese encephalitis virus through MyD88 adaptor molecule-dependent and -independent pathways. J Immunol. 2009;183:2462-74 pubmed publisher |
Jeong M, Piao Z, Kim M, Lee S, Yun S, Sun H, et al. Thioredoxin-interacting protein regulates hematopoietic stem cell quiescence and mobilization under stress conditions. J Immunol. 2009;183:2495-505 pubmed publisher |
Hundt M, Harada Y, De Giorgio L, Tanimura N, Zhang W, Altman A. Palmitoylation-dependent plasma membrane transport but lipid raft-independent signaling by linker for activation of T cells. J Immunol. 2009;183:1685-94 pubmed publisher |
Schraml B, Hildner K, Ise W, Lee W, Smith W, Solomon B, et al. The AP-1 transcription factor Batf controls T(H)17 differentiation. Nature. 2009;460:405-9 pubmed publisher |
Gondek D, Roan N, Starnbach M. T cell responses in the absence of IFN-gamma exacerbate uterine infection with Chlamydia trachomatis. J Immunol. 2009;183:1313-9 pubmed publisher |
Leavenworth J, Ma X, Mo Y, Pauza M. SUMO conjugation contributes to immune deviation in nonobese diabetic mice by suppressing c-Maf transactivation of IL-4. J Immunol. 2009;183:1110-9 pubmed publisher |
Curtis M, Way S, Wilson C. IL-23 promotes the production of IL-17 by antigen-specific CD8 T cells in the absence of IL-12 and type-I interferons. J Immunol. 2009;183:381-7 pubmed publisher |
von Vietinghoff S, Ley K. IL-17A controls IL-17F production and maintains blood neutrophil counts in mice. J Immunol. 2009;183:865-73 pubmed publisher |
Delgoffe G, Kole T, Zheng Y, Zarek P, Matthews K, Xiao B, et al. The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment. Immunity. 2009;30:832-44 pubmed publisher |
Yen J, Ganea D. Interferon beta induces mature dendritic cell apoptosis through caspase-11/caspase-3 activation. Blood. 2009;114:1344-54 pubmed publisher |
Fang C, Zhang X, Miwa T, Song W. Complement promotes the development of inflammatory T-helper 17 cells through synergistic interaction with Toll-like receptor signaling and interleukin-6 production. Blood. 2009;114:1005-15 pubmed publisher |
Lin I, Zhou Z, Crusselle Davis V, Moghimi B, Gandhi K, Anantharaman A, et al. Calpeptin increases the activity of upstream stimulatory factor and induces high level globin gene expression in erythroid cells. J Biol Chem. 2009;284:20130-5 pubmed publisher |
Fukui R, Saitoh S, Matsumoto F, Kozuka Hata H, Oyama M, Tabeta K, et al. Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing. J Exp Med. 2009;206:1339-50 pubmed publisher |
Blue R, Kowalska M, Hirsch J, Murcia M, Janczak C, Harrington A, et al. Structural and therapeutic insights from the species specificity and in vivo antithrombotic activity of a novel alphaIIb-specific alphaIIbbeta3 antagonist. Blood. 2009;114:195-201 pubmed publisher |
Maue A, Eaton S, Lanthier P, Sweet K, Blumerman S, Haynes L. Proinflammatory adjuvants enhance the cognate helper activity of aged CD4 T cells. J Immunol. 2009;182:6129-35 pubmed publisher |
Zheng H, Matte Martone C, Jain D, McNiff J, Shlomchik W. Central memory CD8+ T cells induce graft-versus-host disease and mediate graft-versus-leukemia. J Immunol. 2009;182:5938-48 pubmed publisher |
Newcomb D, Zhou W, Moore M, Goleniewska K, Hershey G, Kolls J, et al. A functional IL-13 receptor is expressed on polarized murine CD4+ Th17 cells and IL-13 signaling attenuates Th17 cytokine production. J Immunol. 2009;182:5317-21 pubmed publisher |
Ben Sasson S, Hu Li J, Quiel J, Cauchetaux S, Ratner M, Shapira I, et al. IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation. Proc Natl Acad Sci U S A. 2009;106:7119-24 pubmed publisher |
Horman S, Velu C, Chaubey A, Bourdeau T, Zhu J, Paul W, et al. Gfi1 integrates progenitor versus granulocytic transcriptional programming. Blood. 2009;113:5466-75 pubmed publisher |
Velu C, Baktula A, Grimes H. Gfi1 regulates miR-21 and miR-196b to control myelopoiesis. Blood. 2009;113:4720-8 pubmed publisher |
Milsom M, Schiedlmeier B, Bailey J, Kim M, Li D, Jansen M, et al. Ectopic HOXB4 overcomes the inhibitory effect of tumor necrosis factor-{alpha} on Fanconi anemia hematopoietic stem and progenitor cells. Blood. 2009;113:5111-20 pubmed publisher |
Hamada H, Garcia Hernandez M, Reome J, Misra S, Strutt T, McKinstry K, et al. Tc17, a unique subset of CD8 T cells that can protect against lethal influenza challenge. J Immunol. 2009;182:3469-81 pubmed publisher |
Zou Z, Schmaier A, Cheng L, Mericko P, Dickeson S, Stricker T, et al. Negative regulation of activated alpha-2 integrins during thrombopoiesis. Blood. 2009;113:6428-39 pubmed publisher |
Chang M, Lee A, Fitzpatrick L, Zhang M, Sun S. NF-kappa B1 p105 regulates T cell homeostasis and prevents chronic inflammation. J Immunol. 2009;182:3131-8 pubmed publisher |
Perona Wright G, Jenkins S, O Connor R, Zienkiewicz D, McSorley H, Maizels R, et al. A pivotal role for CD40-mediated IL-6 production by dendritic cells during IL-17 induction in vivo. J Immunol. 2009;182:2808-15 pubmed publisher |
Gekas C, Rhodes K, Gereige L, Helgadottir H, Ferrari R, Kurdistani S, et al. Mef2C is a lineage-restricted target of Scl/Tal1 and regulates megakaryopoiesis and B-cell homeostasis. Blood. 2009;113:3461-71 pubmed publisher |
Kuo Y, Zaidi S, Gornostaeva S, Komori T, Stein G, Castilla L. Runx2 induces acute myeloid leukemia in cooperation with Cbfbeta-SMMHC in mice. Blood. 2009;113:3323-32 pubmed publisher |
Komatsu N, Mariotti Ferrandiz M, Wang Y, Malissen B, Waldmann H, Hori S. Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity. Proc Natl Acad Sci U S A. 2009;106:1903-8 pubmed publisher |
Allen J, Jaffer Z, Park S, Burgin S, Hofmann C, Sells M, et al. p21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics. Blood. 2009;113:2695-705 pubmed publisher |
Ptak W, Majewska M, Bryniarski K, Ptak M, Lobo F, Zajac K, et al. Epicutaneous immunization with protein antigen in the presence of TLR4 ligand induces TCR alpha beta+CD4+ T contrasuppressor cells that reverse skin-induced suppression of Th1-mediated contact sensitivity. J Immunol. 2009;182:837-50 pubmed |
Viale A, De Franco F, Orleth A, Cambiaghi V, Giuliani V, Bossi D, et al. Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells. Nature. 2009;457:51-6 pubmed publisher |
Praetor A, McBride J, Chiu H, Rangell L, Cabote L, Lee W, et al. Genetic deletion of JAM-C reveals a role in myeloid progenitor generation. Blood. 2009;113:1919-28 pubmed publisher |
Huber M, Brüstle A, Reinhard K, Guralnik A, Walter G, Mahiny A, et al. IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype. Proc Natl Acad Sci U S A. 2008;105:20846-51 pubmed publisher |
Orabona C, Pallotta M, Volpi C, Fallarino F, Vacca C, Bianchi R, et al. SOCS3 drives proteasomal degradation of indoleamine 2,3-dioxygenase (IDO) and antagonizes IDO-dependent tolerogenesis. Proc Natl Acad Sci U S A. 2008;105:20828-33 pubmed publisher |
Haak S, Croxford A, Kreymborg K, Heppner F, Pouly S, Becher B, et al. IL-17A and IL-17F do not contribute vitally to autoimmune neuro-inflammation in mice. J Clin Invest. 2009;119:61-9 pubmed publisher |
Chen Q, Yang W, Gupta S, Biswas P, Smith P, Bhagat G, et al. IRF-4-binding protein inhibits interleukin-17 and interleukin-21 production by controlling the activity of IRF-4 transcription factor. Immunity. 2008;29:899-911 pubmed publisher |
Yamazaki T, Yang X, Chung Y, Fukunaga A, Nurieva R, Pappu B, et al. CCR6 regulates the migration of inflammatory and regulatory T cells. J Immunol. 2008;181:8391-401 pubmed |
Horton S, Walf Vorderwülbecke V, Chatters S, Sebire N, de Boer J, Williams O. Acute myeloid leukemia induced by MLL-ENL is cured by oncogene ablation despite acquisition of complex genetic abnormalities. Blood. 2009;113:4922-9 pubmed publisher |
Kalaitzidis D, Neel B. Flow-cytometric phosphoprotein analysis reveals agonist and temporal differences in responses of murine hematopoietic stem/progenitor cells. PLoS ONE. 2008;3:e3776 pubmed publisher |
Hill J, Hall J, Sun C, Cai Q, Ghyselinck N, Chambon P, et al. Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi Cells. Immunity. 2008;29:758-70 pubmed publisher |
Krivtsov A, Feng Z, Lemieux M, Faber J, Vempati S, Sinha A, et al. H3K79 methylation profiles define murine and human MLL-AF4 leukemias. Cancer Cell. 2008;14:355-68 pubmed publisher |
Carlson M, West M, COGHILL J, Panoskaltsis Mortari A, Blazar B, Serody J. In vitro-differentiated TH17 cells mediate lethal acute graft-versus-host disease with severe cutaneous and pulmonary pathologic manifestations. Blood. 2009;113:1365-74 pubmed publisher |
Sakthivel S, Singh U, Singh S, Taub D, Novakovic K, Lillard J. CXCL10 blockade protects mice from cyclophosphamide-induced cystitis. J Immune Based Ther Vaccines. 2008;6:6 pubmed publisher |
Stritesky G, Yeh N, Kaplan M. IL-23 promotes maintenance but not commitment to the Th17 lineage. J Immunol. 2008;181:5948-55 pubmed |
Yang Q, Kardava L, St Leger A, Martincic K, Varnum Finney B, Bernstein I, et al. E47 controls the developmental integrity and cell cycle quiescence of multipotential hematopoietic progenitors. J Immunol. 2008;181:5885-94 pubmed |
Matsuda S, Mikami Y, Ohtani M, Fujiwara M, Hirata Y, Minowa A, et al. Critical role of class IA PI3K for c-Rel expression in B lymphocytes. Blood. 2009;113:1037-44 pubmed publisher |
Cochrane S, Zhao Y, Welner R, Sun X. Balance between Id and E proteins regulates myeloid-versus-lymphoid lineage decisions. Blood. 2009;113:1016-26 pubmed publisher |
Sutherland R, Olsen J, McKinstry A, Villalta S, Wolters P. Mast cell IL-6 improves survival from Klebsiella pneumonia and sepsis by enhancing neutrophil killing. J Immunol. 2008;181:5598-605 pubmed |
Kamimura D, Bevan M. Endoplasmic reticulum stress regulator XBP-1 contributes to effector CD8+ T cell differentiation during acute infection. J Immunol. 2008;181:5433-41 pubmed |
Vassiliou E, Kesler O, Tadros J, Ganea D. Bone marrow-derived dendritic cells generated in the presence of resolvin E1 induce apoptosis of activated CD4+ T cells. J Immunol. 2008;181:4534-44 pubmed |
Csik xf3 s T, Reijmers R, Uren A, Spaargaren M, Pals S. Instant conditional transgenesis in the mouse hematopoietic compartment. J Immunol Methods. 2008;339:259-63 pubmed publisher |
Zhou Y, Du W, Koretsky T, Bagby G, Pang Q. TAT-mediated intracellular delivery of NPM-derived peptide induces apoptosis in leukemic cells and suppresses leukemogenesis in mice. Blood. 2008;112:2474-83 pubmed publisher |
Kreymborg K, Etzensperger R, Dumoutier L, Haak S, Rebollo A, Buch T, et al. IL-22 is expressed by Th17 cells in an IL-23-dependent fashion, but not required for the development of autoimmune encephalomyelitis. J Immunol. 2007;179:8098-104 pubmed |
Li J, Sejas D, Zhang X, Qiu Y, Nattamai K, Rani R, et al. TNF-alpha induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells. J Clin Invest. 2007;117:3283-95 pubmed |
Wu Y, Welte T, Michaud M, Madri J. PECAM-1: a multifaceted regulator of megakaryocytopoiesis. Blood. 2007;110:851-9 pubmed |
Wang R, Li C, Xu X, Zheng Y, Xiao C, Zerfas P, et al. A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression. Cell Metab. 2005;2:399-409 pubmed |
Yang M, Hase H, Legarda Addison D, Varughese L, Seed B, Ting A. B cell maturation antigen, the receptor for a proliferation-inducing ligand and B cell-activating factor of the TNF family, induces antigen presentation in B cells. J Immunol. 2005;175:2814-24 pubmed |
Yamauchi A, Marchal C, Molitoris J, Pech N, Knaus U, Towe J, et al. Rac GTPase isoform-specific regulation of NADPH oxidase and chemotaxis in murine neutrophils in vivo. Role of the C-terminal polybasic domain. J Biol Chem. 2005;280:953-64 pubmed |
Metcalf D, Mifsud S, Di Rago L. Stem cell factor can stimulate the formation of eosinophils by two types of murine eosinophil progenitor cells. Stem Cells. 2002;20:460-9 pubmed |
Ge Q, Palliser D, Eisen H, Chen J. Homeostatic T cell proliferation in a T cell-dendritic cell coculture system. Proc Natl Acad Sci U S A. 2002;99:2983-8 pubmed |
Feraud O, Cao Y, Vittet D. Embryonic stem cell-derived embryoid bodies development in collagen gels recapitulates sprouting angiogenesis. Lab Invest. 2001;81:1669-81 pubmed |
