This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
protein
product name :
Mouse IL-13 Recombinant Protein, PeproTech
catalog :
210-13-10UG
quantity :
10 ug
price :
US 226.00
citations: 121
Reference
Miyauchi S, Arimoto K, Liu M, Zhang Y, Zhang D. Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18. Cell Rep. 2023;42:113560 pubmed publisher
Xiao H, Du X, Tao Z, Jing N, Bao S, Gao W, et al. Taurine Inhibits Ferroptosis Mediated by the Crosstalk between Tumor Cells and Tumor-Associated Macrophages in Prostate Cancer. Adv Sci (Weinh). 2023;:e2303894 pubmed publisher
Theocharidis G, Rahmani S, Lee S, Li Z, Lobao A, Kounas K, et al. Murine macrophages or their secretome delivered in alginate dressings enhance impaired wound healing in diabetic mice. Biomaterials. 2022;288:121692 pubmed publisher
Wang L, Noyer L, Wang Y, Tao A, Li W, Zhu J, et al. ORAI3 is dispensable for store-operated Ca2+ entry and immune responses by lymphocytes and macrophages. J Gen Physiol. 2022;154: pubmed publisher
Larue M, Parker S, Puccini J, Cammer M, Kimmelman A, Bar Sagi D. Metabolic reprogramming of tumor-associated macrophages by collagen turnover promotes fibrosis in pancreatic cancer. Proc Natl Acad Sci U S A. 2022;119:e2119168119 pubmed publisher
Dichtl S, Sanin D, Koss C, Willenborg S, Petzold A, Tanzer M, et al. Gene-selective transcription promotes the inhibition of tissue reparative macrophages by TNF. Life Sci Alliance. 2022;5: pubmed publisher
Dai H, Lou S, Zhang Y, Thanawala M, Huang K, Ji L, et al. Transcriptional neural-like signaling contributes to an immune-suppressive tumor microenvironment. FASEB Bioadv. 2022;4:76-89 pubmed publisher
Park I, Goddard M, Cole J, Zanin N, Lyytik xe4 inen L, Lehtim xe4 ki T, et al. C-type lectin receptor CLEC4A2 promotes tissue adaptation of macrophages and protects against atherosclerosis. Nat Commun. 2022;13:215 pubmed publisher
Drurey C, Lindholm H, Coakley G, Poveda M, L xf6 ser S, Doolan R, et al. Intestinal epithelial tuft cell induction is negated by a murine helminth and its secreted products. J Exp Med. 2022;219: pubmed publisher
Li B, Song X, Guo W, Hou Y, Hu H, Ge W, et al. Single-Cell Transcriptome Profiles Reveal Fibrocytes as Potential Targets of Cell Therapies for Abdominal Aortic Aneurysm. Front Cardiovasc Med. 2021;8:753711 pubmed publisher
Willenborg S, Sanin D, Jais A, Ding X, Ulas T, Nüchel J, et al. Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing. Cell Metab. 2021;33:2398-2414.e9 pubmed publisher
Ji W, Li D, Wei D, Gu A, Yang Y, Peng J. Cytochrome P450 26A1 Modulates the Polarization of Uterine Macrophages During the Peri-Implantation Period. Front Immunol. 2021;12:763067 pubmed publisher
Fremder M, Kim S, Khamaysi A, Shimshilashvili L, Eini Rider H, Park I, et al. A transepithelial pathway delivers succinate to macrophages, thus perpetuating their pro-inflammatory metabolic state. Cell Rep. 2021;36:109521 pubmed publisher
Ying H, Fang M, Hang Q, Chen Y, Qian X, Chen M. Pirfenidone modulates macrophage polarization and ameliorates radiation-induced lung fibrosis by inhibiting the TGF-β1/Smad3 pathway. J Cell Mol Med. 2021;25:8662-8675 pubmed publisher
Ren J, Han X, Lohner H, Liang R, Liang S, Wang H. Serum- and Glucocorticoid-Inducible Kinase 1 Promotes Alternative Macrophage Polarization and Restrains Inflammation through FoxO1 and STAT3 Signaling. J Immunol. 2021;: pubmed publisher
Dichtl S, Lindenthal L, Zeitler L, Behnke K, Schlösser D, Strobl B, et al. Lactate and IL6 define separable paths of inflammatory metabolic adaptation. Sci Adv. 2021;7: pubmed publisher
Liu Y, Du M, Lin H. Histone deacetylase 9 deficiency exaggerates uterine M2 macrophage polarization. J Cell Mol Med. 2021;25:7690-7708 pubmed publisher
de Lucía Finkel P, Sherwood C, Saranchova I, Xia W, Munro L, Pfeifer C, et al. Serum free culture for the expansion and study of type 2 innate lymphoid cells. Sci Rep. 2021;11:12233 pubmed publisher
Wang Y, Wang X, Yu J, Ma F, Li Z, Zhou Y, et al. Targeting monoamine oxidase A-regulated tumor-associated macrophage polarization for cancer immunotherapy. Nat Commun. 2021;12:3530 pubmed publisher
Liu L, Wu Y, Wang B, Jiang Y, Lin L, Li X, et al. DA-DRD5 signaling controls colitis by regulating colonic M1/M2 macrophage polarization. Cell Death Dis. 2021;12:500 pubmed publisher
Conde E, Bertrand R, Balbino B, Bonnefoy J, Stackowicz J, Caillot N, et al. Dual vaccination against IL-4 and IL-13 protects against chronic allergic asthma in mice. Nat Commun. 2021;12:2574 pubmed publisher
Cleary M, Bharathy N, Abraham J, Kim J, Rudzinski E, Michalek J, et al. Interleukin-4 Receptor Inhibition Targeting Metastasis Independent of Macrophages. Mol Cancer Ther. 2021;20:906-914 pubmed publisher
Gonzalez Figueroa P, Roco J, Papa I, Núñez Villacís L, Stanley M, Linterman M, et al. Follicular regulatory T cells produce neuritin to regulate B cells. Cell. 2021;184:1775-1789.e19 pubmed publisher
Schumacher M, Hsieh J, Liu C, Appel K, Waddell A, Almohazey D, et al. Sprouty2 limits intestinal tuft and goblet cell numbers through GSK3β-mediated restriction of epithelial IL-33. Nat Commun. 2021;12:836 pubmed publisher
Hu G, Su Y, Kang B, Fan Z, Dong T, Brown D, et al. High-throughput phenotypic screen and transcriptional analysis identify new compounds and targets for macrophage reprogramming. Nat Commun. 2021;12:773 pubmed publisher
Ying W, Gao H, Dos Reis F, Bandyopadhyay G, Ofrecio J, Luo Z, et al. MiR-690, an exosomal-derived miRNA from M2-polarized macrophages, improves insulin sensitivity in obese mice. Cell Metab. 2021;33:781-790.e5 pubmed publisher
Wang H, Ashton R, Hensel J, Lee J, Khattar V, Wang Y, et al. RANKL-Targeted Combination Therapy with Osteoprotegerin Variant Devoid of TRAIL Binding Exerts Biphasic Effects on Skeletal Remodeling and Antitumor Immunity. Mol Cancer Ther. 2020;19:2585-2597 pubmed publisher
Zaghdoudi S, Decaup E, Belhabib I, Samain R, Cassant Sourdy S, Rochotte J, et al. FAK activity in cancer-associated fibroblasts is a prognostic marker and a druggable key metastatic player in pancreatic cancer. EMBO Mol Med. 2020;12:e12010 pubmed publisher
Yan K, Da T, Bian Z, He Y, Liu M, Liu Q, et al. Multi-omics analysis identifies FoxO1 as a regulator of macrophage function through metabolic reprogramming. Cell Death Dis. 2020;11:800 pubmed publisher
Li N, Stewart T, Sheng L, Shi M, Cilento E, Wu Y, et al. Immunoregulation of microglial polarization: an unrecognized physiological function of α-synuclein. J Neuroinflammation. 2020;17:272 pubmed publisher
Bai J, Zhang Y, Zheng X, Huang M, Cheng W, Shan H, et al. LncRNA MM2P-induced, exosome-mediated transfer of Sox9 from monocyte-derived cells modulates primary chondrocytes. Cell Death Dis. 2020;11:763 pubmed publisher
Yuan Y, Jiang Y, Wang B, Guo Y, Gong P, Xiang L. Deficiency of Calcitonin Gene-Related Peptide Affects Macrophage Polarization in Osseointegration. Front Physiol. 2020;11:733 pubmed publisher
Nasser H, Adhikary P, Abdel Daim A, Noyori O, Panaampon J, Kariya R, et al. Establishment of bone marrow-derived M-CSF receptor-dependent self-renewing macrophages. Cell Death Discov. 2020;6:63 pubmed publisher
Esmaeilniakooshkghazi A, George S, Biswas R, Khurana S. Mouse intestinal tuft cells express advillin but not villin. Sci Rep. 2020;10:8877 pubmed publisher
Wu Y, Wu B, Zhang Z, Lu H, Fan C, Qi Q, et al. Heme protects intestinal mucosal barrier in DSS-induced colitis through regulating macrophage polarization in both HO-1-dependent and HO-1-independent way. FASEB J. 2020;34:8028-8043 pubmed publisher
Francisco D, Wang Y, Conway M, Hurbon A, Dy A, Addison K, et al. Surfactant Protein-A Protects against IL-13-Induced Inflammation in Asthma. J Immunol. 2020;204:2829-2839 pubmed publisher
Malinina A, Dikeman D, Westbrook R, Moats M, Gidner S, Poonyagariyagorn H, et al. IL10 deficiency promotes alveolar enlargement and lymphoid dysmorphogenesis in the aged murine lung. Aging Cell. 2020;19:e13130 pubmed publisher
Devalaraja S, To T, Folkert I, Natesan R, Alam M, Li M, et al. Tumor-Derived Retinoic Acid Regulates Intratumoral Monocyte Differentiation to Promote Immune Suppression. Cell. 2020;180:1098-1114.e16 pubmed publisher
McGinty J, Ting H, Billipp T, Nadjsombati M, Khan D, Barrett N, et al. Tuft-Cell-Derived Leukotrienes Drive Rapid Anti-helminth Immunity in the Small Intestine but Are Dispensable for Anti-protist Immunity. Immunity. 2020;52:528-541.e7 pubmed publisher
Delacher M, Imbusch C, Hotz Wagenblatt A, Mallm J, Bauer K, Simon M, et al. Precursors for Nonlymphoid-Tissue Treg Cells Reside in Secondary Lymphoid Organs and Are Programmed by the Transcription Factor BATF. Immunity. 2020;52:295-312.e11 pubmed publisher
Beckert H, Meyer Martin H, Buhl R, Taube C, Reuter S. Single and Synergistic Effects of Type 2 Cytokines on Eosinophils and Asthma Hallmarks. J Immunol. 2020;204:550-558 pubmed publisher
Tian Y, Guo Y, Zhu P, Zhang D, Liu S, Tang M, et al. TRIM59 loss in M2 macrophages promotes melanoma migration and invasion by upregulating MMP-9 and Madcam1. Aging (Albany NY). 2019;11:8623-8641 pubmed publisher
Lin Y, Li B, Yang X, Liu T, Shi T, Deng B, et al. Non-hematopoietic STAT6 induces epithelial tight junction dysfunction and promotes intestinal inflammation and tumorigenesis. Mucosal Immunol. 2019;12:1304-1315 pubmed publisher
Mellal K, Omri S, Mulumba M, Tahiri H, Fortin C, Dorion M, et al. Immunometabolic modulation of retinal inflammation by CD36 ligand. Sci Rep. 2019;9:12903 pubmed publisher
Di Mitri D, Mirenda M, Vasilevska J, Calcinotto A, Delaleu N, Revandkar A, et al. Re-education of Tumor-Associated Macrophages by CXCR2 Blockade Drives Senescence and Tumor Inhibition in Advanced Prostate Cancer. Cell Rep. 2019;28:2156-2168.e5 pubmed publisher
Jiang S, Lyu C, Zhao P, Li W, Kong W, Huang C, et al. Cryoprotectant enables structural control of porous scaffolds for exploration of cellular mechano-responsiveness in 3D. Nat Commun. 2019;10:3491 pubmed publisher
Dahlgren M, Jones S, Cautivo K, Dubinin A, Ortiz Carpena J, Farhat S, et al. Adventitial Stromal Cells Define Group 2 Innate Lymphoid Cell Tissue Niches. Immunity. 2019;50:707-722.e6 pubmed publisher
Kiesewetter A, Cursiefen C, Eming S, Hos D. Phase-specific functions of macrophages determine injury-mediated corneal hem- and lymphangiogenesis. Sci Rep. 2019;9:308 pubmed publisher
Minshawi F, White M, Muller W, Humphreys N, Jackson D, Campbell B, et al. Human TNF-Luc reporter mouse: A new model to quantify inflammatory responses. Sci Rep. 2019;9:193 pubmed publisher
Kubota T, Inoue M, Kubota N, Takamoto I, Mineyama T, Iwayama K, et al. Downregulation of macrophage Irs2 by hyperinsulinemia impairs IL-4-indeuced M2a-subtype macrophage activation in obesity. Nat Commun. 2018;9:4863 pubmed publisher
Wodsedalek D, Paddock S, Wan T, Auchampach J, Kenarsary A, Tsaih S, et al. IL-13 promotes in vivo neonatal cardiomyocyte cell cycle activity and heart regeneration. Am J Physiol Heart Circ Physiol. 2019;316:H24-H34 pubmed publisher
Barik S, Cattin Roy A, Miller M, Ukah T, Zaghouani H. IL-4 and IL-13 Guide Early Thymic Progenitors To Mature toward Dendritic Cells. J Immunol. 2018;201:2947-2958 pubmed publisher
Proto J, Doran A, Gusarova G, Yurdagul A, Sozen E, Subramanian M, et al. Regulatory T Cells Promote Macrophage Efferocytosis during Inflammation Resolution. Immunity. 2018;49:666-677.e6 pubmed publisher
Montoro D, Haber A, Biton M, Vinarsky V, Lin B, Birket S, et al. A revised airway epithelial hierarchy includes CFTR-expressing ionocytes. Nature. 2018;560:319-324 pubmed publisher
Nadjsombati M, McGinty J, Lyons Cohen M, Jaffe J, DiPeso L, Schneider C, et al. Detection of Succinate by Intestinal Tuft Cells Triggers a Type 2 Innate Immune Circuit. Immunity. 2018;49:33-41.e7 pubmed publisher
Dahal L, Huang C, Stopforth R, Mead A, Chan K, Bowater J, et al. Shaving Is an Epiphenomenon of Type I and II Anti-CD20-Mediated Phagocytosis, whereas Antigenic Modulation Limits Type I Monoclonal Antibody Efficacy. J Immunol. 2018;201:1211-1221 pubmed publisher
Reinhart R, Kaufmann T. IL-4 enhances survival of in vitro-differentiated mouse basophils through transcription-independent signaling downstream of PI3K. Cell Death Dis. 2018;9:713 pubmed publisher
Eenjes E, Mertens T, Buscop van Kempen M, van Wijck Y, Taube C, Rottier R, et al. A novel method for expansion and differentiation of mouse tracheal epithelial cells in culture. Sci Rep. 2018;8:7349 pubmed publisher
Strnadel J, Carromeu C, Bardy C, Navarro M, Platoshyn O, Glud A, et al. Survival of syngeneic and allogeneic iPSC-derived neural precursors after spinal grafting in minipigs. Sci Transl Med. 2018;10: pubmed publisher
Rothberg J, Maganti H, Jrade H, Porter C, Palidwor G, Cafariello C, et al. Mtf2-PRC2 control of canonical Wnt signaling is required for definitive erythropoiesis. Cell Discov. 2018;4:21 pubmed publisher
Weng Q, Wang J, Wang J, Wang J, Sattar F, Zhang Z, et al. Lenalidomide regulates CNS autoimmunity by promoting M2 macrophages polarization. Cell Death Dis. 2018;9:251 pubmed publisher
Dabitao D, Hedrich C, Wang F, Vacharathit V, Bream J. Cell-Specific Requirements for STAT Proteins and Type I IFN Receptor Signaling Discretely Regulate IL-24 and IL-10 Expression in NK Cells and Macrophages. J Immunol. 2018;200:2154-2164 pubmed publisher
Zhang W, Kim H, Lv J, Zhao N, Ma X. Golgi Phosphoprotein 2 Is a Novel Regulator of IL-12 Production and Macrophage Polarization. J Immunol. 2018;200:1480-1488 pubmed publisher
Lee S, Charmoy M, Romano A, Paun A, Chaves M, Cope F, et al. Mannose receptor high, M2 dermal macrophages mediate nonhealing Leishmania major infection in a Th1 immune environment. J Exp Med. 2018;215:357-375 pubmed publisher
Ayaub E, Dubey A, Imani J, Botelho F, Kolb M, Richards C, et al. Overexpression of OSM and IL-6 impacts the polarization of pro-fibrotic macrophages and the development of bleomycin-induced lung fibrosis. Sci Rep. 2017;7:13281 pubmed publisher
Ching K, COLLARINI E, Abdiche Y, Bedinger D, Pedersen D, Izquierdo S, et al. Chickens with humanized immunoglobulin genes generate antibodies with high affinity and broad epitope coverage to conserved targets. MAbs. 2017;:1-10 pubmed publisher
Oetjen L, Mack M, Feng J, Whelan T, Niu H, Guo C, et al. Sensory Neurons Co-opt Classical Immune Signaling Pathways to Mediate Chronic Itch. Cell. 2017;171:217-228.e13 pubmed publisher
Bai L, Liu X, Zheng Q, Kong M, Zhang X, Hu R, et al. M2-like macrophages in the fibrotic liver protect mice against lethal insults through conferring apoptosis resistance to hepatocytes. Sci Rep. 2017;7:10518 pubmed publisher
Aladegbami B, Barron L, Bao J, Colasanti J, Erwin C, Warner B, et al. Epithelial cell specific Raptor is required for initiation of type 2 mucosal immunity in small intestine. Sci Rep. 2017;7:5580 pubmed publisher
White A, Baik S, Parnell S, Holland A, Brombacher F, Jenkinson W, et al. A type 2 cytokine axis for thymus emigration. J Exp Med. 2017;214:2205-2216 pubmed publisher
Pelly V, Coomes S, Kannan Y, Gialitakis M, Entwistle L, Perez Lloret J, et al. Interleukin 4 promotes the development of ex-Foxp3 Th2 cells during immunity to intestinal helminths. J Exp Med. 2017;214:1809-1826 pubmed publisher
Poh A, Love C, Masson F, Preaudet A, Tsui C, Whitehead L, et al. Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer Progression. Cancer Cell. 2017;31:563-575.e5 pubmed publisher
Li J, Kong D, Wang Q, Wu W, Tang Y, Bai T, et al. Niacin ameliorates ulcerative colitis via prostaglandin D2-mediated D prostanoid receptor 1 activation. EMBO Mol Med. 2017;9:571-588 pubmed publisher
Malek Mohammadi M, Kattih B, Grund A, Froese N, Korf Klingebiel M, Gigina A, et al. The transcription factor GATA4 promotes myocardial regeneration in neonatal mice. EMBO Mol Med. 2017;9:265-279 pubmed publisher
Zimmer J, Weitnauer M, Boutin S, Küblbeck G, Thiele S, Walker P, et al. Nuclear Localization of Suppressor of Cytokine Signaling-1 Regulates Local Immunity in the Lung. Front Immunol. 2016;7:514 pubmed
Haribhai D, Ziegelbauer J, Jia S, Upchurch K, Yan K, Schmitt E, et al. Alternatively Activated Macrophages Boost Induced Regulatory T and Th17 Cell Responses during Immunotherapy for Colitis. J Immunol. 2016;196:3305-17 pubmed publisher
Li Y, Qi W, Song X, Lv S, Zhang H, Yang Q. Huaier extract suppresses breast cancer via regulating tumor-associated macrophages. Sci Rep. 2016;6:20049 pubmed publisher
Gerbe F, Sidot E, Smyth D, Ohmoto M, Matsumoto I, Dardalhon V, et al. Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites. Nature. 2016;529:226-30 pubmed publisher
Cimen Bozkus C, Elzey B, Crist S, Ellies L, Ratliff T. Expression of Cationic Amino Acid Transporter 2 Is Required for Myeloid-Derived Suppressor Cell-Mediated Control of T Cell Immunity. J Immunol. 2015;195:5237-50 pubmed publisher
Tukler Henriksson J, Coursey T, Corry D, de Paiva C, Pflugfelder S. IL-13 Stimulates Proliferation and Expression of Mucin and Immunomodulatory Genes in Cultured Conjunctival Goblet Cells. Invest Ophthalmol Vis Sci. 2015;56:4186-97 pubmed publisher
Le T, Karmouty Quintana H, Melicoff E, Le T, Weng T, Chen N, et al. Blockade of IL-6 Trans signaling attenuates pulmonary fibrosis. J Immunol. 2014;193:3755-68 pubmed publisher
Li J, Razumilava N, Gores G, Walters S, Mizuochi T, Mourya R, et al. Biliary repair and carcinogenesis are mediated by IL-33-dependent cholangiocyte proliferation. J Clin Invest. 2014;124:3241-51 pubmed publisher
Fichtner Feigl S, Kesselring R, Martin M, Obermeier F, Ruemmele P, Kitani A, et al. IL-13 orchestrates resolution of chronic intestinal inflammation via phosphorylation of glycogen synthase kinase-3β. J Immunol. 2014;192:3969-80 pubmed publisher
Trav xe9 s P, Pardo V, Pimentel Santillana M, Gonz xe1 lez Rodr xed guez x, Mojena M, Rico D, et al. Pivotal role of protein tyrosine phosphatase 1B (PTP1B) in the macrophage response to pro-inflammatory and anti-inflammatory challenge. Cell Death Dis. 2014;5:e1125 pubmed publisher
Tang Y, Li T, Li J, Yang J, Liu H, Zhang X, et al. Jmjd3 is essential for the epigenetic modulation of microglia phenotypes in the immune pathogenesis of Parkinson's disease. Cell Death Differ. 2014;21:369-80 pubmed publisher
Bouffi C, Rochman M, Zust C, Stucke E, Kartashov A, Fulkerson P, et al. IL-33 markedly activates murine eosinophils by an NF-?B-dependent mechanism differentially dependent upon an IL-4-driven autoinflammatory loop. J Immunol. 2013;191:4317-25 pubmed publisher
Sasaki O, Imamura M, Yamazumi Y, Harada H, Matsumoto T, Okunishi K, et al. Alendronate attenuates eosinophilic airway inflammation associated with suppression of Th2 cytokines, Th17 cytokines, and eotaxin-2. J Immunol. 2013;191:2879-89 pubmed publisher
Chang H, Miaw S, Tseng W, Sun Y, Liu C, Tsao H, et al. PTPN22 modulates macrophage polarization and susceptibility to dextran sulfate sodium-induced colitis. J Immunol. 2013;191:2134-43 pubmed publisher
Knolle M, Nakajima T, Hergrueter A, Gupta K, Polverino F, Craig V, et al. Adam8 limits the development of allergic airway inflammation in mice. J Immunol. 2013;190:6434-49 pubmed publisher
Ohta S, Imamura M, Xing W, Boyce J, Balestrieri B. Group V secretory phospholipase A2 is involved in macrophage activation and is sufficient for macrophage effector functions in allergic pulmonary inflammation. J Immunol. 2013;190:5927-38 pubmed publisher
Han H, Headley M, Xu W, Comeau M, Zhou B, Ziegler S. Thymic stromal lymphopoietin amplifies the differentiation of alternatively activated macrophages. J Immunol. 2013;190:904-12 pubmed publisher
Stanya K, Jacobi D, Liu S, Bhargava P, Dai L, Gangl M, et al. Direct control of hepatic glucose production by interleukin-13 in mice. J Clin Invest. 2013;123:261-71 pubmed publisher
Herranz S, Traves P, Luque A, Hortelano S. Role of the tumor suppressor ARF in macrophage polarization: Enhancement of the M2 phenotype in ARF-deficient mice. Oncoimmunology. 2012;1:1227-1238 pubmed
Rafei M, Rouette A, Brochu S, Vanegas J, Perreault C. Differential effects of ?c cytokines on postselection differentiation of CD8 thymocytes. Blood. 2013;121:107-17 pubmed publisher
Masuoka M, Shiraishi H, Ohta S, Suzuki S, Arima K, Aoki S, et al. Periostin promotes chronic allergic inflammation in response to Th2 cytokines. J Clin Invest. 2012;122:2590-600 pubmed publisher
Yang M, Meng J, Cheng X, Lei J, Guo H, Zhang W, et al. Multiwalled carbon nanotubes interact with macrophages and influence tumor progression and metastasis. Theranostics. 2012;2:258-70 pubmed publisher
Sugimoto K, Kudo M, Sundaram A, Ren X, Huang K, Bernstein X, et al. The ?v?6 integrin modulates airway hyperresponsiveness in mice by regulating intraepithelial mast cells. J Clin Invest. 2012;122:748-58 pubmed publisher
Hoffman C, Park S, Daley E, Emson C, Louten J, Sisco M, et al. Interleukin-19: a constituent of the regulome that controls antigen presenting cells in the lungs and airway responses to microbial products. PLoS ONE. 2011;6:e27629 pubmed publisher
Balce D, Li B, Allan E, Rybicka J, Krohn R, Yates R. Alternative activation of macrophages by IL-4 enhances the proteolytic capacity of their phagosomes through synergistic mechanisms. Blood. 2011;118:4199-208 pubmed publisher
Zhang W, Xu W, Xiong S. Macrophage differentiation and polarization via phosphatidylinositol 3-kinase/Akt-ERK signaling pathway conferred by serum amyloid P component. J Immunol. 2011;187:1764-77 pubmed publisher
L Abbate C, Cipriano I, Perez Hurtado E, Leao S, Carneiro C, Machado J. TGF-?-mediated sustained ERK1/2 activity promotes the inhibition of intracellular growth of Mycobacterium avium in epithelioid cells surrogates. PLoS ONE. 2011;6:e21465 pubmed publisher
Anthony R, Kobayashi T, Wermeling F, Ravetch J. Intravenous gammaglobulin suppresses inflammation through a novel T(H)2 pathway. Nature. 2011;475:110-3 pubmed publisher
Stock A, Booth S, Cerundolo V. Prostaglandin E2 suppresses the differentiation of retinoic acid-producing dendritic cells in mice and humans. J Exp Med. 2011;208:761-73 pubmed publisher
Lindley A, Crapster Pregont M, Liu Y, Kuperman D. 12/15-lipoxygenase is an interleukin-13 and interferon-? counterregulated-mediator of allergic airway inflammation. Mediators Inflamm. 2010;2010: pubmed publisher
Nagarkar D, Bowman E, Schneider D, Wang Q, Shim J, Zhao Y, et al. Rhinovirus infection of allergen-sensitized and -challenged mice induces eotaxin release from functionally polarized macrophages. J Immunol. 2010;185:2525-35 pubmed publisher
Milner J, Orekov T, Ward J, Cheng L, Torres Velez F, Junttila I, et al. Sustained IL-4 exposure leads to a novel pathway for hemophagocytosis, inflammation, and tissue macrophage accumulation. Blood. 2010;116:2476-83 pubmed publisher
Torres D, Dieudonné A, Ryffel B, Vilain E, Si Tahar M, Pichavant M, et al. Double-stranded RNA exacerbates pulmonary allergic reaction through TLR3: implication of airway epithelium and dendritic cells. J Immunol. 2010;185:451-9 pubmed publisher
Wang G, Miyahara Y, Guo Z, Khattar M, Stepkowski S, Chen W. "Default" generation of neonatal regulatory T cells. J Immunol. 2010;185:71-8 pubmed publisher
Rodríguez Prados J, Traves P, Cuenca J, Rico D, Aragones J, Martín Sanz P, et al. Substrate fate in activated macrophages: a comparison between innate, classic, and alternative activation. J Immunol. 2010;185:605-14 pubmed publisher
Nemeth K, Keane Myers A, Brown J, Metcalfe D, Gorham J, Gorham J, et al. Bone marrow stromal cells use TGF-beta to suppress allergic responses in a mouse model of ragweed-induced asthma. Proc Natl Acad Sci U S A. 2010;107:5652-7 pubmed publisher
Geiben Lynn R, Greenland J, Frimpong Boateng K, Letvin N. Non-classical natural killer T cells modulate plasmid DNA vaccine antigen expression and vaccine-elicited immune responses by MCP-1 secretion after interaction with a beta2-microglobulin-independent CD1d. J Biol Chem. 2009;284:33800-6 pubmed publisher
Niedermeier M, Reich B, Rodriguez Gomez M, Denzel A, Schmidbauer K, Göbel N, et al. CD4+ T cells control the differentiation of Gr1+ monocytes into fibrocytes. Proc Natl Acad Sci U S A. 2009;106:17892-7 pubmed publisher
Tachdjian R, Mathias C, Al Khatib S, Bryce P, Kim H, Blaeser F, et al. Pathogenicity of a disease-associated human IL-4 receptor allele in experimental asthma. J Exp Med. 2009;206:2191-204 pubmed publisher
DeNardo D, Barreto J, Andreu P, Vasquez L, Tawfik D, Kolhatkar N, et al. CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. Cancer Cell. 2009;16:91-102 pubmed publisher
Goswami S, Angkasekwinai P, Shan M, Greenlee K, Barranco W, Polikepahad S, et al. Divergent functions for airway epithelial matrix metalloproteinase 7 and retinoic acid in experimental asthma. Nat Immunol. 2009;10:496-503 pubmed publisher
Lim R, Kobzik L. Transplacental passage of interleukins 4 and 13?. PLoS ONE. 2009;4:e4660 pubmed publisher
Medoff B, Seung E, Hong S, Thomas S, Sandall B, Duffield J, et al. CD11b+ myeloid cells are the key mediators of Th2 cell homing into the airway in allergic inflammation. J Immunol. 2009;182:623-35 pubmed
Marathe C, Bradley M, Hong C, Chao L, Wilpitz D, Salazar J, et al. Preserved glucose tolerance in high-fat-fed C57BL/6 mice transplanted with PPARgamma-/-, PPARdelta-/-, PPARgammadelta-/-, or LXRalphabeta-/- bone marrow. J Lipid Res. 2009;50:214-24 pubmed publisher
Mackinnon A, Farnworth S, Hodkinson P, Henderson N, Atkinson K, Leffler H, et al. Regulation of alternative macrophage activation by galectin-3. J Immunol. 2008;180:2650-8 pubmed
Suto A, Nakajima H, Tokumasa N, Takatori H, Kagami S, Suzuki K, et al. Murine plasmacytoid dendritic cells produce IFN-gamma upon IL-4 stimulation. J Immunol. 2005;175:5681-9 pubmed
Ge Q, Palliser D, Eisen H, Chen J. Homeostatic T cell proliferation in a T cell-dendritic cell coculture system. Proc Natl Acad Sci U S A. 2002;99:2983-8 pubmed
product information
Product Type :
Protein
Product Name :
Mouse IL-13 Recombinant Protein, PeproTech
Catalog # :
210-13-10UG
Quantity :
10 ug
Price :
US 226.00
Clonality :
Recombinant
Purity :
purified
Reactivity :
Mouse
Applications :
ELISA: Assay-dependent, Functional Assay: Assay-dependent, Western Blot: Assay-dependent
Species :
Mouse
Storage :
-20 C
Description :
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.
Format :
Lyophilized
Applications w/Dilutions :
ELISA: Assay-dependent, Functional Assay: Assay-dependent, Western Blot: Assay-dependent
Aliases :
ALRH; ALRH antibody; BHR1; il 13; Il13; Il-13; IL-13; cytokine; ILN; Interleukin; interleukin 13; Interleukin13; interleukin-13; interleukin-13 precursor; L13; MGC116786; MGC116788; MGC116789; NC30; NC30 antibody; P600; P600 antibody; T-cell activation protein P600
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA