| Reference |
|---|
Lee D, Kim Y, Park J, Choi J, Jeong H, Park C. Development of Genetically Engineered Feeder Cells for Natural Killer Cell Expansion. Anticancer Res. 2023;43:3897-3904 pubmed publisher |
Shiqi L, Jiasi Z, Lvzhe C, Huailong X, Liping H, Lin L, et al. Durable remission related to CAR-T persistence in R/R B-ALL and long-term persistence potential of prime CAR-T. Mol Ther Oncolytics. 2023;29:107-117 pubmed publisher |
Tsai D, Wang C, Schiro P, Chen N, Tseng J. Tracking B Cell Memory to SARS-CoV-2 Using Rare Cell Analysis System. Vaccines (Basel). 2023;11: pubmed publisher |
Fichtner M, Hoehn K, Ford E, Mané Damas M, Oh S, Waters P, et al. Reemergence of pathogenic, autoantibody-producing B cell clones in myasthenia gravis following B cell depletion therapy. Acta Neuropathol Commun. 2022;10:154 pubmed publisher |
Manolakou T, Nikolopoulos D, Gkikas D, Filia A, Samiotaki M, Stamatakis G, et al. ATR-mediated DNA damage responses underlie aberrant B cell activity in systemic lupus erythematosus. Sci Adv. 2022;8:eabo5840 pubmed publisher |
SoRelle E, Reinoso Vizcaino N, Horn G, Luftig M. Epstein-Barr virus perpetuates B cell germinal center dynamics and generation of autoimmune-associated phenotypes in vitro. Front Immunol. 2022;13:1001145 pubmed publisher |
Niehues H, Rikken G, van Vlijmen Willems I, Rodijk Olthuis D, van Erp P, Zeeuwen P, et al. Identification of Keratinocyte Mitogens: Implications for Hyperproliferation in Psoriasis and Atopic Dermatitis. JID Innov. 2022;2:100066 pubmed publisher |
He Y, Gallman A, Xie C, Shen Q, Ma J, Wolfreys F, et al. P2RY8 variants in lupus patients uncover a role for the receptor in immunological tolerance. J Exp Med. 2022;219: pubmed publisher |
Schneider M, Emmenegger M, Xu C, Condado Morales I, Meisl G, Turelli P, et al. Microfluidic characterisation reveals broad range of SARS-CoV-2 antibody affinity in human plasma. Life Sci Alliance. 2022;5: pubmed publisher |
Wu B, Rice L, Shrimpton J, Lawless D, Walker K, Carter C, et al. Biallelic mutations in calcium release activated channel regulator 2A (CRACR2A) cause a primary immunodeficiency disorder. elife. 2021;10: pubmed publisher |
Deng B, Pan J, Liu Z, Liu S, Chen Y, Qu X, et al. Peripheral leukemia burden at time of apheresis negatively affects the clinical efficacy of CART19 in refractory or relapsed B-ALL. Mol Ther Methods Clin Dev. 2021;23:633-643 pubmed publisher |
Rotolo A, Atherton M, Kasper B, Haran K, Mason N. Genetic re-direction of canine primary T cells for clinical trial use in pet dogs with spontaneous cancer. STAR Protoc. 2021;2:100905 pubmed publisher |
Kuehn H, Chang J, Yamashita M, Niemela J, Zou C, Okuyama K, et al. T and B cell abnormalities, pneumocystis pneumonia, and chronic lymphocytic leukemia associated with an AIOLOS defect in patients. J Exp Med. 2021;218: pubmed publisher |
Zebley C, Abdelsamed H, Ghoneim H, Alli S, Brown C, Haydar D, et al. Proinflammatory cytokines promote TET2-mediated DNA demethylation during CD8 T cell effector differentiation. Cell Rep. 2021;37:109796 pubmed publisher |
Sokal A, Barba Spaeth G, Fern xe1 ndez I, Broketa M, Azzaoui I, de La Selle A, et al. mRNA vaccination of naive and COVID-19-recovered individuals elicits potent memory B cells that recognize SARS-CoV-2 variants. Immunity. 2021;54:2893-2907.e5 pubmed publisher |
Aguilar Bretones M, Westerhuis B, Raadsen M, de Bruin E, Chandler F, Okba N, et al. Seasonal coronavirus-specific B cells with limited SARS-CoV-2 cross-reactivity dominate the IgG response in severe COVID-19. J Clin Invest. 2021;131: pubmed publisher |
Gong C, Krupka J, Gao J, Grigoropoulos N, Giotopoulos G, Asby R, et al. Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis. Mol Cell. 2021;81:4059-4075.e11 pubmed publisher |
YAO Y, Chen Z, Zhang H, Chen C, Zeng M, Yunis J, et al. Selenium-GPX4 axis protects follicular helper T cells from ferroptosis. Nat Immunol. 2021;22:1127-1139 pubmed publisher |
Pieters T, T Sas S, Vanhee S, Almeida A, Driege Y, Roels J, et al. Cyclin D2 overexpression drives B1a-derived MCL-like lymphoma in mice. J Exp Med. 2021;218: pubmed publisher |
Szodoray P, Andersen T, Heinzelbecker J, Imbery J, Huszthy P, Stanford S, et al. Integration of T helper and BCR signals governs enhanced plasma cell differentiation of memory B cells by regulation of CD45 phosphatase activity. Cell Rep. 2021;36:109525 pubmed publisher |
Basar R, Uprety N, Ensley E, Daher M, Klein K, Martinez F, et al. Generation of glucocorticoid-resistant SARS-CoV-2 T cells for adoptive cell therapy. Cell Rep. 2021;36:109432 pubmed publisher |
Possama xef D, Pag xe9 G, Pan xe8 s R, Gagnon x, Lapointe R. CD40L-Stimulated B Lymphocytes Are Polarized toward APC Functions after Exposure to IL-4 and IL-21. J Immunol. 2021;207:77-89 pubmed publisher |
Ito T, Kawai Y, Yasui Y, Iriguchi S, Minagawa A, Ishii T, et al. The therapeutic potential of multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-1derived iPS cells. Commun Biol. 2021;4:694 pubmed publisher |
Deng J, Chen Q, Chen Z, Liang K, Gao X, Wang X, et al. The metabolic hormone leptin promotes the function of TFH cells and supports vaccine responses. Nat Commun. 2021;12:3073 pubmed publisher |
Mandolesi M, Sheward D, Hanke L, Ma J, Pushparaj P, Perez Vidakovics L, et al. SARS-CoV-2 protein subunit vaccination of mice and rhesus macaques elicits potent and durable neutralizing antibody responses. Cell Rep Med. 2021;2:100252 pubmed publisher |
Dejnirattisai W, Zhou D, Ginn H, Duyvesteyn H, Supasa P, Case J, et al. The antigenic anatomy of SARS-CoV-2 receptor binding domain. Cell. 2021;184:2183-2200.e22 pubmed publisher |
Ehx G, Larouche J, Durette C, Laverdure J, Hesnard L, Vincent K, et al. Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes. Immunity. 2021;54:737-752.e10 pubmed publisher |
Rubanova D, Dadova P, Vašíček O, Kubala L. Pseurotin D Inhibits the Activation of Human Lymphocytes. Int J Mol Sci. 2021;22: pubmed publisher |
Price M, Scharer C, Kania A, Randall T, Boss J. Conserved Epigenetic Programming and Enhanced Heme Metabolism Drive Memory B Cell Reactivation. J Immunol. 2021;206:1493-1504 pubmed publisher |
Vlahava V, Murrell I, Zhuang L, Aicheler R, Lim E, Miners K, et al. Monoclonal antibodies targeting nonstructural viral antigens can activate ADCC against human cytomegalovirus. J Clin Invest. 2021;131: pubmed publisher |
Sokal A, Chappert P, Barba Spaeth G, Roeser A, Fourati S, Azzaoui I, et al. Maturation and persistence of the anti-SARS-CoV-2 memory B cell response. Cell. 2021;184:1201-1213.e14 pubmed publisher |
Byazrova M, Yusubalieva G, Spiridonova A, Efimov G, Mazurov D, Baranov K, et al. Pattern of circulating SARS-CoV-2-specific antibody-secreting and memory B-cell generation in patients with acute COVID-19. Clin Transl Immunology. 2021;10:e1245 pubmed publisher |
Vavassori V, Mercuri E, Marcovecchio G, Castiello M, Schiroli G, Albano L, et al. Modeling, optimization, and comparable efficacy of T cell and hematopoietic stem cell gene editing for treating hyper-IgM syndrome. EMBO Mol Med. 2021;13:e13545 pubmed publisher |
Tu H, Nivarthi U, Graham N, Eisenhauer P, Delacruz M, Pierce K, et al. Stimulation of B Cell Immunity in Flavivirus-Naive Individuals by the Tetravalent Live Attenuated Dengue Vaccine TV003. Cell Rep Med. 2020;1:100155 pubmed publisher |
Almeida L, Dhillon LaBrooy A, Castro C, Adossa N, Carriche G, Guderian M, et al. Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis. Immunity. 2021;54:68-83.e6 pubmed publisher |
Evans R, Antonelou M, Sathiananthamoorthy S, Rega M, Henderson S, Ceron Gutierrez L, et al. Inherited salt-losing tubulopathies are associated with immunodeficiency due to impaired IL-17 responses. Nat Commun. 2020;11:4368 pubmed publisher |
Helfricht A, Thijssen P, Rother M, Shah R, Du L, Takada S, et al. Loss of ZBTB24 impairs nonhomologous end-joining and class-switch recombination in patients with ICF syndrome. J Exp Med. 2020;217: pubmed publisher |
Ricker E, Verma A, Marullo R, Gupta S, Ye C, Pannellini T, et al. Selective dysregulation of ROCK2 activity promotes aberrant transcriptional networks in ABC diffuse large B-cell lymphoma. Sci Rep. 2020;10:13094 pubmed publisher |
Wang Y, Wang C, Cai X, Mou C, Cui X, Zhang Y, et al. IL-21 Stimulates the expression and activation of cell cycle regulators and promotes cell proliferation in EBV-positive diffuse large B cell lymphoma. Sci Rep. 2020;10:12326 pubmed publisher |
Sedda S, Dinallo V, Marafini I, Franz xe8 E, Paoluzi O, Izzo R, et al. mTOR sustains inflammatory response in celiac disease. Sci Rep. 2020;10:10798 pubmed publisher |
Meyer L, Verbist K, Albeituni S, Scull B, Bassett R, Stroh A, et al. JAK/STAT pathway inhibition sensitizes CD8 T cells to dexamethasone-induced apoptosis in hyperinflammation. Blood. 2020;136:657-668 pubmed publisher |
Mitra A, Andrews M, Roh W, De Macedo M, Hudgens C, Carapeto F, et al. Spatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma. Nat Commun. 2020;11:1839 pubmed publisher |
Deal C, Thauland T, Stiehm E, Garcia Lloret M, Butte M. Intact B-Cell Signaling and Function With Host B-Cells 47 Years After Transplantation for X-SCID. Front Immunol. 2020;11:415 pubmed publisher |
Wang J, Hasan F, Frey A, Li H, Park J, Pan K, et al. Histone Deacetylase Inhibitors and IL21 Cooperate to Reprogram Human Effector CD8+ T Cells to Memory T Cells. Cancer Immunol Res. 2020;8:794-805 pubmed publisher |
Wang Z, Zhao M, Yin J, Liu L, Hu L, Huang Y, et al. E4BP4-mediated inhibition of T follicular helper cell differentiation is compromised in autoimmune diseases. J Clin Invest. 2020;130:3717-3733 pubmed publisher |
Dowty M, Lin T, Jesson M, Hegen M, Martin D, Katkade V, et al. Janus kinase inhibitors for the treatment of rheumatoid arthritis demonstrate similar profiles of in vitro cytokine receptor inhibition. Pharmacol Res Perspect. 2019;7:e00537 pubmed publisher |
Onodera T, Hashi K, Shukla R, Miki M, Takai Todaka R, Fujimoto A, et al. Immune-Focusing Properties of Virus-like Particles Improve Protective IgA Responses. J Immunol. 2019;203:3282-3292 pubmed publisher |
Linnebacher A, Mayer P, Marnet N, Bergmann F, Herpel E, Revia S, et al. Interleukin 21 Receptor/Ligand Interaction Is Linked to Disease Progression in Pancreatic Cancer. Cells. 2019;8: pubmed publisher |
Adachi Y, Tonouchi K, Nithichanon A, Kuraoka M, Watanabe A, Shinnakasu R, et al. Exposure of an occluded hemagglutinin epitope drives selection of a class of cross-protective influenza antibodies. Nat Commun. 2019;10:3883 pubmed publisher |
Spencer S, Kostel Bal S, Egner W, Lango Allen H, Raza S, Ma C, et al. Loss of the interleukin-6 receptor causes immunodeficiency, atopy, and abnormal inflammatory responses. J Exp Med. 2019;: pubmed publisher |
Fan J, Liang H, Ji X, Wang S, Xue J, Li D, et al. CTL-mediated immunotherapy can suppress SHIV rebound in ART-free macaques. Nat Commun. 2019;10:2257 pubmed publisher |
Davis C, Jackson K, McElroy A, Halfmann P, Huang J, Chennareddy C, et al. Longitudinal Analysis of the Human B Cell Response to Ebola Virus Infection. Cell. 2019;: pubmed publisher |
Watanabe A, McCarthy K, Kuraoka M, Schmidt A, Adachi Y, Onodera T, et al. Antibodies to a Conserved Influenza Head Interface Epitope Protect by an IgG Subtype-Dependent Mechanism. Cell. 2019;177:1124-1135.e16 pubmed publisher |
Zumaquero E, Stone S, Scharer C, Jenks S, Nellore A, Mousseau B, et al. IFNγ induces epigenetic programming of human T-bethi B cells and promotes TLR7/8 and IL-21 induced differentiation. elife. 2019;8: pubmed publisher |
Komuczki J, Tuzlak S, Friebel E, Hartwig T, Spath S, Rosenstiel P, et al. Fate-Mapping of GM-CSF Expression Identifies a Discrete Subset of Inflammation-Driving T Helper Cells Regulated by Cytokines IL-23 and IL-1β. Immunity. 2019;: pubmed publisher |
Kim D, Park H, Park H, Lee J, Ko C, Gye M, et al. Estrogen receptor α in T cells suppresses follicular helper T cell responses and prevents autoimmunity. Exp Mol Med. 2019;51:41 pubmed publisher |
Oda H, Beck D, Kuehn H, Sampaio Moura N, Hoffmann P, Ibarra M, et al. Second Case of HOIP Deficiency Expands Clinical Features and Defines Inflammatory Transcriptome Regulated by LUBAC. Front Immunol. 2019;10:479 pubmed publisher |
Stephenson S, Care M, Fan I, Zougman A, Westhead D, Doody G, et al. Growth Factor-like Gene Regulation Is Separable from Survival and Maturation in Antibody-Secreting Cells. J Immunol. 2019;202:1287-1300 pubmed publisher |
Al Maskari M, Care M, Robinson E, Cocco M, Tooze R, Doody G. Site-1 protease function is essential for the generation of antibody secreting cells and reprogramming for secretory activity. Sci Rep. 2018;8:14338 pubmed publisher |
Nguyen D, Garimalla S, Xiao H, Kyu S, Albizua I, Galipeau J, et al. Factors of the bone marrow microniche that support human plasma cell survival and immunoglobulin secretion. Nat Commun. 2018;9:3698 pubmed publisher |
Ngai H, Tian G, Courtney A, Ravari S, Guo L, Liu B, et al. IL-21 Selectively Protects CD62L+ NKT Cells and Enhances Their Effector Functions for Adoptive Immunotherapy. J Immunol. 2018;201:2141-2153 pubmed publisher |
Jalali S, Price Troska T, Paludo J, Villasboas J, Kim H, Yang Z, et al. Soluble PD-1 ligands regulate T-cell function in Waldenstrom macroglobulinemia. Blood Adv. 2018;2:1985-1997 pubmed publisher |
Avery D, Kane A, Nguyen T, Lau A, Nguyen A, Lenthall H, et al. Germline-activating mutations in PIK3CD compromise B cell development and function. J Exp Med. 2018;215:2073-2095 pubmed publisher |
Sayin I, Radtke A, Vella L, Jin W, Wherry E, Buggert M, et al. Spatial distribution and function of T follicular regulatory cells in human lymph nodes. J Exp Med. 2018;215:1531-1542 pubmed publisher |
Lichtenegger F, Rothe M, Schnorfeil F, Deiser K, Krupka C, Augsberger C, et al. Targeting LAG-3 and PD-1 to Enhance T Cell Activation by Antigen-Presenting Cells. Front Immunol. 2018;9:385 pubmed publisher |
De S, Zhang B, Shih T, Singh S, Winkler A, Donnelly R, et al. B Cell-Intrinsic Role for IRF5 in TLR9/BCR-Induced Human B Cell Activation, Proliferation, and Plasmablast Differentiation. Front Immunol. 2017;8:1938 pubmed publisher |
McCarthy K, Watanabe A, Kuraoka M, Do K, McGee C, Sempowski G, et al. Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses Are Abundant in Adult Human Repertoires. Immunity. 2018;48:174-184.e9 pubmed publisher |
Suan D, Kräutler N, Mååg J, Butt D, Bourne K, Hermes J, et al. CCR6 Defines Memory B Cell Precursors in Mouse and Human Germinal Centers, Revealing Light-Zone Location and Predominant Low Antigen Affinity. Immunity. 2017;47:1142-1153.e4 pubmed publisher |
Sabins N, Chornoguz O, Leander K, Kaplan F, Carter R, Kinder M, et al. TIM-3 Engagement Promotes Effector Memory T Cell Differentiation of Human Antigen-Specific CD8 T Cells by Activating mTORC1. J Immunol. 2017;199:4091-4102 pubmed publisher |
Ameratunga R, Koopmans W, Woon S, Leung E, Lehnert K, Slade C, et al. Epistatic interactions between mutations of TACI (TNFRSF13B) and TCF3 result in a severe primary immunodeficiency disorder and systemic lupus erythematosus. Clin Transl Immunology. 2017;6:e159 pubmed publisher |
Malik S, Sadhu S, Elesela S, Pandey R, Chawla A, Sharma D, et al. Transcription factor Foxo1 is essential for IL-9 induction in T helper cells. Nat Commun. 2017;8:815 pubmed publisher |
Schwerd T, Twigg S, Aschenbrenner D, Manrique S, Miller K, Taylor I, et al. A biallelic mutation in IL6ST encoding the GP130 co-receptor causes immunodeficiency and craniosynostosis. J Exp Med. 2017;214:2547-2562 pubmed publisher |
Zhang Y, Ma C, Lawrence M, Break T, O Connell M, Lyons J, et al. PD-L1 up-regulation restrains Th17 cell differentiation in STAT3 loss- and STAT1 gain-of-function patients. J Exp Med. 2017;214:2523-2533 pubmed publisher |
Magri G, Comerma L, Pybus M, Sintes J, Lligé D, Segura Garzón D, et al. Human Secretory IgM Emerges from Plasma Cells Clonally Related to Gut Memory B Cells and Targets Highly Diverse Commensals. Immunity. 2017;47:118-134.e8 pubmed publisher |
Arumugakani G, Stephenson S, Newton D, Rawstron A, Emery P, Doody G, et al. Early Emergence of CD19-Negative Human Antibody-Secreting Cells at the Plasmablast to Plasma Cell Transition. J Immunol. 2017;198:4618-4628 pubmed publisher |
Bassani Sternberg M, Bräunlein E, Klar R, Engleitner T, Sinitcyn P, Audehm S, et al. Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry. Nat Commun. 2016;7:13404 pubmed publisher |
Ouyang F, Wu R, Wei Y, Liu R, Yang D, Xiao X, et al. Dendritic cell-elicited B-cell activation fosters immune privilege via IL-10 signals in hepatocellular carcinoma. Nat Commun. 2016;7:13453 pubmed publisher |
Dijkstra D, Meyer Bahlburg A. Human Basophils Modulate Plasma Cell Differentiation and Maturation. J Immunol. 2017;198:229-238 pubmed |
Su K, Watanabe A, Yeh C, Kelsoe G, Kuraoka M. Efficient Culture of Human Naive and Memory B Cells for Use as APCs. J Immunol. 2016;197:4163-4176 pubmed |
Serr I, Fürst R, Ott V, Scherm M, Nikolaev A, Gökmen F, et al. miRNA92a targets KLF2 and the phosphatase PTEN signaling to promote human T follicular helper precursors in T1D islet autoimmunity. Proc Natl Acad Sci U S A. 2016;113:E6659-E6668 pubmed |
Cantaert T, Schickel J, Bannock J, Ng Y, Massad C, Delmotte F, et al. Decreased somatic hypermutation induces an impaired peripheral B cell tolerance checkpoint. J Clin Invest. 2016;126:4289-4302 pubmed publisher |
Wang Y, Ma C, Ling Y, Bousfiha A, Camcioglu Y, Jacquot S, et al. Dual T cell- and B cell-intrinsic deficiency in humans with biallelic RLTPR mutations. J Exp Med. 2016;213:2413-2435 pubmed |
Vijayan D, Mohd Redzwan N, Avery D, Wirasinha R, Brink R, Walters G, et al. IL-27 Directly Enhances Germinal Center B Cell Activity and Potentiates Lupus in Sanroque Mice. J Immunol. 2016;197:3008-3017 pubmed |
Aggelakopoulou M, Kourepini E, Paschalidis N, Simoes D, Kalavrizioti D, Dimisianos N, et al. ER?-Dependent Direct Suppression of Human and Murine Th17 Cells and Treatment of Established Central Nervous System Autoimmunity by a Neurosteroid. J Immunol. 2016;197:2598-609 pubmed publisher |
Zhang C, Gong Y, Zhu W, Qi Y, Yang C, Fu Y, et al. Augmentation of Circulating Follicular Helper T Cells and Their Impact on Autoreactive B Cells in Myasthenia Gravis. J Immunol. 2016;197:2610-7 pubmed publisher |
Ma C, Wong N, Rao G, Nguyen A, Avery D, Payne K, et al. Unique and shared signaling pathways cooperate to regulate the differentiation of human CD4+ T cells into distinct effector subsets. J Exp Med. 2016;213:1589-608 pubmed publisher |
Nagafuchi Y, Shoda H, Sumitomo S, Nakachi S, Kato R, Tsuchida Y, et al. Immunophenotyping of rheumatoid arthritis reveals a linkage between HLA-DRB1 genotype, CXCR4 expression on memory CD4(+) T cells, and disease activity. Sci Rep. 2016;6:29338 pubmed publisher |
Care M, Stephenson S, Barnes N, Fan I, Zougman A, El Sherbiny Y, et al. Network Analysis Identifies Proinflammatory Plasma Cell Polarization for Secretion of ISG15 in Human Autoimmunity. J Immunol. 2016;197:1447-59 pubmed publisher |
Guo B, Zhang L, Chiorazzi N, Rothstein T. IL-4 rescues surface IgM expression in chronic lymphocytic leukemia. Blood. 2016;128:553-62 pubmed publisher |
DeKosky B, Lungu O, Park D, Johnson E, Charab W, Chrysostomou C, et al. Large-scale sequence and structural comparisons of human naive and antigen-experienced antibody repertoires. Proc Natl Acad Sci U S A. 2016;113:E2636-45 pubmed publisher |
Dimitrova M, Zenarruzabeitia O, Borrego F, Simhadri V. CD300c is uniquely expressed on CD56 bright Natural Killer Cells and differs from CD300a upon ligand recognition. Sci Rep. 2016;6:23942 pubmed publisher |
Serr I, Fürst R, Achenbach P, Scherm M, Gökmen F, Haupt F, et al. Type 1 diabetes vaccine candidates promote human Foxp3(+)Treg induction in humanized mice. Nat Commun. 2016;7:10991 pubmed publisher |
Hubbard N, Hagin D, Sommer K, Song Y, Khan I, Clough C, et al. Targeted gene editing restores regulated CD40L function in X-linked hyper-IgM syndrome. Blood. 2016;127:2513-22 pubmed publisher |
Yin J, Leavenworth J, Li Y, Luo Q, Xie H, Liu X, et al. Ezh2 regulates differentiation and function of natural killer cells through histone methyltransferase activity. Proc Natl Acad Sci U S A. 2015;112:15988-93 pubmed publisher |
Ortega Molina A, Boss I, Canela A, Pan H, Jiang Y, Zhao C, et al. The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development. Nat Med. 2015;21:1199-208 pubmed publisher |
Xiao L, Jia L, Zhang Y, Yu S, Wu X, Yang B, et al. Human IL-21+IFN-γ+CD4+ T cells in nasal polyps are regulated by IL-12. Sci Rep. 2015;5:12781 pubmed publisher |
Xu X, Shang Q, Chen X, Nie W, Zou Z, Huang A, et al. Reversal of B-cell hyperactivation and functional impairment is associated with HBsAg seroconversion in chronic hepatitis B patients. Cell Mol Immunol. 2015;12:309-16 pubmed publisher |
Chavele K, Merry E, Ehrenstein M. Cutting edge: circulating plasmablasts induce the differentiation of human T follicular helper cells via IL-6 production. J Immunol. 2015;194:2482-5 pubmed publisher |
García Carmona Y, Cols M, Ting A, Radigan L, Yuk F, Zhang L, et al. Differential induction of plasma cells by isoforms of human TACI. Blood. 2015;125:1749-58 pubmed publisher |
Ramos Amaya A, RodrÃguez Bayona B, López Blanco R, Andújar E, Pérez Alegre M, Campos Caro A, et al. Survival of human circulating antigen-induced plasma cells is supported by plasma cell-niche cytokines and T follicular helper lymphocytes. J Immunol. 2015;194:1031-8 pubmed publisher |
Gordon S, Doster M, Kines R, Keele B, Brocca Cofano E, Guan Y, et al. Antibody to the gp120 V1/V2 loops and CD4+ and CD8+ T cell responses in protection from SIVmac251 vaginal acquisition and persistent viremia. J Immunol. 2014;193:6172-83 pubmed publisher |
Zhu S, Phatarpekar P, Denman C, Senyukov V, Somanchi S, Nguyen Jackson H, et al. Transcription of the activating receptor NKG2D in natural killer cells is regulated by STAT3 tyrosine phosphorylation. Blood. 2014;124:403-11 pubmed publisher |
Isik G, van Montfort T, Chung N, Moore J, Sanders R. Autoantibodies induced by chimeric cytokine-HIV envelope glycoprotein immunogens. J Immunol. 2014;192:4628-35 pubmed publisher |
Jandus C, Boligan K, Chijioke O, Liu H, Dahlhaus M, Démoulins T, et al. Interactions between Siglec-7/9 receptors and ligands influence NK cell-dependent tumor immunosurveillance. J Clin Invest. 2014;124:1810-20 pubmed publisher |
Karnell J, Dimasi N, Karnell F, Fleming R, Kuta E, Wilson M, et al. CD19 and CD32b differentially regulate human B cell responsiveness. J Immunol. 2014;192:1480-90 pubmed publisher |
Berglund L, Avery D, Ma C, Moens L, Deenick E, Bustamante J, et al. IL-21 signalling via STAT3 primes human naive B cells to respond to IL-2 to enhance their differentiation into plasmablasts. Blood. 2013;122:3940-50 pubmed publisher |
Rodríguez Bayona B, Ramos Amaya A, López Blanco R, Campos Caro A, Brieva J. STAT-3 activation by differential cytokines is critical for human in vivo-generated plasma cell survival and Ig secretion. J Immunol. 2013;191:4996-5004 pubmed publisher |
Byun M, Ma C, Akcay A, Pedergnana V, Palendira U, Myoung J, et al. Inherited human OX40 deficiency underlying classic Kaposi sarcoma of childhood. J Exp Med. 2013;210:1743-59 pubmed publisher |
Wolfl M, Schwinn S, Yoo Y, Reß M, Braun M, Chopra M, et al. Src-kinase inhibitors sensitize human cells of myeloid origin to Toll-like-receptor-induced interleukin 12 synthesis. Blood. 2013;122:1203-13 pubmed publisher |
Liu Y, Yu S, Li Z, Ma J, Zhang Y, Wang H, et al. TGF-β enhanced IL-21-induced differentiation of human IL-21-producing CD4+ T cells via Smad3. PLoS ONE. 2013;8:e64612 pubmed publisher |
Kotlarz D, Zietara N, Uzel G, Weidemann T, Braun C, Diestelhorst J, et al. Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome. J Exp Med. 2013;210:433-43 pubmed publisher |
Schilling B, Harasymczuk M, Schuler P, Egan J, Ferrone S, Whiteside T. IRX-2, a novel immunotherapeutic, enhances functions of human dendritic cells. PLoS ONE. 2013;8:e47234 pubmed publisher |
Vallières F, Girard D. IL-21 enhances phagocytosis in mononuclear phagocyte cells: identification of spleen tyrosine kinase as a novel molecular target of IL-21. J Immunol. 2013;190:2904-12 pubmed publisher |
Ding B, Bi E, Chen H, Yu J, Ye B. IL-21 and CD40L synergistically promote plasma cell differentiation through upregulation of Blimp-1 in human B cells. J Immunol. 2013;190:1827-36 pubmed publisher |
Cocco M, Stephenson S, Care M, Newton D, Barnes N, Davison A, et al. In vitro generation of long-lived human plasma cells. J Immunol. 2012;189:5773-85 pubmed publisher |
Vaeth M, Schliesser U, Müller G, Reissig S, Satoh K, Tuettenberg A, et al. Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3+ regulatory T cells. Proc Natl Acad Sci U S A. 2012;109:16258-63 pubmed publisher |
Hodge L, Ziesmer S, Yang Z, Secreto F, Gertz M, Novak A, et al. IL-21 in the bone marrow microenvironment contributes to IgM secretion and proliferation of malignant cells in Waldenstrom macroglobulinemia. Blood. 2012;120:3774-82 pubmed publisher |
Ochsenreither S, Majeti R, Schmitt T, Stirewalt D, Keilholz U, Loeb K, et al. Cyclin-A1 represents a new immunogenic targetable antigen expressed in acute myeloid leukemia stem cells with characteristics of a cancer-testis antigen. Blood. 2012;119:5492-501 pubmed publisher |
Ma C, Avery D, Chan A, Batten M, Bustamante J, Boisson Dupuis S, et al. Functional STAT3 deficiency compromises the generation of human T follicular helper cells. Blood. 2012;119:3997-4008 pubmed publisher |
Nagy N, Adori M, Rasul A, Heuts F, Salamon D, Ujvári D, et al. Soluble factors produced by activated CD4+ T cells modulate EBV latency. Proc Natl Acad Sci U S A. 2012;109:1512-7 pubmed publisher |
Butler M, Imataki O, Yamashita Y, Tanaka M, Ans xe9 n S, Berezovskaya A, et al. Ex vivo expansion of human CD8+ T cells using autologous CD4+ T cell help. PLoS ONE. 2012;7:e30229 pubmed publisher |
Rodríguez Bayona B, Ramos Amaya A, Bernal J, Campos Caro A, Brieva J. Cutting edge: IL-21 derived from human follicular helper T cells acts as a survival factor for secondary lymphoid organ, but not for bone marrow, plasma cells. J Immunol. 2012;188:1578-81 pubmed publisher |
Sammicheli S, Dang V, Ruffin N, Pham H, Lantto R, Vivar N, et al. IL-7 promotes CD95-induced apoptosis in B cells via the IFN-?/STAT1 pathway. PLoS ONE. 2011;6:e28629 pubmed publisher |
Recher M, Berglund L, Avery D, Cowan M, Gennery A, Smart J, et al. IL-21 is the primary common ? chain-binding cytokine required for human B-cell differentiation in vivo. Blood. 2011;118:6824-35 pubmed publisher |
Karnell J, Karnell F, Stephens G, Rajan B, Morehouse C, Li Y, et al. Mycophenolic acid differentially impacts B cell function depending on the stage of differentiation. J Immunol. 2011;187:3603-12 pubmed publisher |
Kardava L, Moir S, Wang W, Ho J, Buckner C, Posada J, et al. Attenuation of HIV-associated human B cell exhaustion by siRNA downregulation of inhibitory receptors. J Clin Invest. 2011;121:2614-24 pubmed publisher |
Chevalier N, Jarrossay D, Ho E, Avery D, Ma C, Yu D, et al. CXCR5 expressing human central memory CD4 T cells and their relevance for humoral immune responses. J Immunol. 2011;186:5556-68 pubmed publisher |
Ansari N, Kumar R, Gautam S, Nylen S, Singh O, Sundar S, et al. IL-27 and IL-21 are associated with T cell IL-10 responses in human visceral leishmaniasis. J Immunol. 2011;186:3977-85 pubmed publisher |
Tran E, Nielsen J, Wick D, Ng A, Johnson L, Nesslinger N, et al. Polyfunctional T-cell responses are disrupted by the ovarian cancer ascites environment and only partially restored by clinically relevant cytokines. PLoS ONE. 2010;5:e15625 pubmed publisher |
Kis L, Gerasimcik N, Salamon D, Persson E, Nagy N, Klein G, et al. STAT6 signaling pathway activated by the cytokines IL-4 and IL-13 induces expression of the Epstein-Barr virus-encoded protein LMP-1 in absence of EBNA-2: implications for the type II EBV latent gene expression in Hodgkin lymphoma. Blood. 2011;117:165-74 pubmed publisher |
Lee S, Yun S, Piao Z, Jeong M, Kim D, Jung H, et al. Suppressor of cytokine signaling 2 regulates IL-15-primed human NK cell function via control of phosphorylated Pyk2. J Immunol. 2010;185:917-28 pubmed publisher |
Kis L, Salamon D, Persson E, Nagy N, Scheeren F, Spits H, et al. IL-21 imposes a type II EBV gene expression on type III and type I B cells by the repression of C- and activation of LMP-1-promoter. Proc Natl Acad Sci U S A. 2010;107:872-7 pubmed publisher |
Avery D, Deenick E, Ma C, Suryani S, Simpson N, Chew G, et al. B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans. J Exp Med. 2010;207:155-71 pubmed publisher |
Suryani S, Fulcher D, Santner Nanan B, Nanan R, Wong M, Shaw P, et al. Differential expression of CD21 identifies developmentally and functionally distinct subsets of human transitional B cells. Blood. 2010;115:519-29 pubmed publisher |
Ma C, Suryani S, Avery D, Chan A, Nanan R, Santner Nanan B, et al. Early commitment of naïve human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12. Immunol Cell Biol. 2009;87:590-600 pubmed publisher |
Pal R, Janz M, Galson D, Gries M, Li S, Johrens K, et al. C/EBPbeta regulates transcription factors critical for proliferation and survival of multiple myeloma cells. Blood. 2009;114:3890-8 pubmed publisher |
Lindemann M, Hu Z, Benczik M, Liu K, Gaffen S. Differential regulation of the IL-17 receptor by gammac cytokines: inhibitory signaling by the phosphatidylinositol 3-kinase pathway. J Biol Chem. 2008;283:14100-8 pubmed publisher |
Good K, Bryant V, Tangye S. Kinetics of human B cell behavior and amplification of proliferative responses following stimulation with IL-21. J Immunol. 2006;177:5236-47 pubmed |
