Human IL-16 (129 aa) Recombinant Protein, PeproTech | Invitrogen 200-16-10UG product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

protein

product name :

Human IL-16 (129 aa) Recombinant Protein, PeproTech

catalog :

200-16-10UG

quantity :

10 ug

price :

US 227.00

citations: 11

Reference
Bouhaddou M, Memon D, Meyer B, White K, Rezelj V, Correa Marrero M, et al. The Global Phosphorylation Landscape of SARS-CoV-2 Infection. Cell. 2020;182:685-712.e19 pubmed publisher
Rothberg J, Maganti H, Jrade H, Porter C, Palidwor G, Cafariello C, et al. Mtf2-PRC2 control of canonical Wnt signaling is required for definitive erythropoiesis. Cell Discov. 2018;4:21 pubmed publisher
Ciraci E, Della Bella S, Salvucci O, Rofani C, Segarra M, Bason C, et al. Adult human circulating CD34⁻Lin⁻CD45⁻CD133⁻ cells can differentiate into hematopoietic and endothelial cells. Blood. 2011;118:2105-15 pubmed publisher
Gilbert L, Hemann M. DNA damage-mediated induction of a chemoresistant niche. Cell. 2010;143:355-66 pubmed publisher
Kirouac D, Ito C, Csaszar E, Roch A, Yu M, Sykes E, et al. Dynamic interaction networks in a hierarchically organized tissue. Mol Syst Biol. 2010;6:417 pubmed publisher
Bauer A, Villunger A, Labi V, Fischer S, Strasser A, Wagner H, et al. The NF-kappaB regulator Bcl-3 and the BH3-only proteins Bim and Puma control the death of activated T cells. Proc Natl Acad Sci U S A. 2006;103:10979-84 pubmed
Ferland C, Flamand N, Davoine F, Chakir J, Laviolette M. IL-16 activates plasminogen-plasmin system and promotes human eosinophil migration into extracellular matrix via CCR3-chemokine-mediated signaling and by modulating CD4 eosinophil expression. J Immunol. 2004;173:4417-24 pubmed
Della Bella S, Nicola S, Timofeeva I, Villa M, Santoro A, Berardi A. Are interleukin-16 and thrombopoietin new tools for the in vitro generation of dendritic cells?. Blood. 2004;104:4020-8 pubmed
Hemminki A, Kanerva A, Liu B, Wang M, Alvarez R, Siegal G, et al. Modulation of coxsackie-adenovirus receptor expression for increased adenoviral transgene expression. Cancer Res. 2003;63:847-53 pubmed
Ogasawara H, Takeda Hirokawa N, Sekigawa I, Hashimoto H, Kaneko Y, Hirose S. Inhibitory effect of interleukin-16 on interleukin-2 production by CD4+ T cells. Immunology. 1999;96:215-9 pubmed
Klimiuk P, Goronzy J, Weyand C. IL-16 as an anti-inflammatory cytokine in rheumatoid synovitis. J Immunol. 1999;162:4293-9 pubmed

product information

Product Type :

Protein

Product Name :

Human IL-16 (129 aa) Recombinant Protein, PeproTech

Catalog # :

200-16-10UG

Quantity :

10 ug

Price :

US 227.00

Clonality :

Recombinant

Purity :

purified

Reactivity :

Human

Applications :

ELISA: Assay-dependent, Functional Assay: Assay-dependent, Western Blot: Assay-dependent

Species :

Human

Storage :

-20 C

Description :

The protein encoded by IL-16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of IL-16 undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants.

Format :

Lyophilized

Applications w/Dilutions :

ELISA: Assay-dependent, Functional Assay: Assay-dependent, Western Blot: Assay-dependent

Aliases :

FLJ16806; FLJ42735; FLJ44234; H-IL-16; il 16; Il16; IL-16; ILN; Interleukin; interleukin 16; Interleukin16; Interleukin-16; LCF; Lymphocyte chemoattractant factor; M-IL-16; mKIAA4048; neuronal interleukin 16; NIL16; PRIL16; prIL-16; prointerleukin 16; Pro-interleukin-16