This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
protein
product name :
Human IL-13 Recombinant Protein, PeproTech
catalog :
200-13-10UG
quantity :
10 ug
price :
US 226.00
citations: 111
Reference
Barnes J, Yoshida M, He P, Worlock K, Lindeboom R, Suo C, et al. Early human lung immune cell development and its role in epithelial cell fate. Sci Immunol. 2023;8:eadf9988 pubmed publisher
Xiao H, Du X, Tao Z, Jing N, Bao S, Gao W, et al. Taurine Inhibits Ferroptosis Mediated by the Crosstalk between Tumor Cells and Tumor-Associated Macrophages in Prostate Cancer. Adv Sci (Weinh). 2023;:e2303894 pubmed publisher
Oshima E, Hayashi Y, Xie Z, Sato H, Hitomi S, Shibuta I, et al. M2 macrophage-derived cathepsin S promotes peripheral nerve regeneration via fibroblast-Schwann cell-signaling relay. J Neuroinflammation. 2023;20:258 pubmed publisher
Rivera K, Bliton R, Burclaff J, Czerwinski M, Liu J, Trueblood J, et al. Hypoxia Primes Human ISCs for Interleukin-Dependent Rescue of Stem Cell Activity. Cell Mol Gastroenterol Hepatol. 2023;16:823-846 pubmed publisher
Xu J, Shi Q, Lou J, Wang B, Wang W, Niu J, et al. Chordoma recruits and polarizes tumor-associated macrophages via secreting CCL5 to promote malignant progression. J Immunother Cancer. 2023;11: pubmed publisher
Riera Domingo C, Leite Gomes E, Charatsidou I, Zhao P, Carr xe1 G, Cappellesso F, et al. Breast tumors interfere with endothelial TRAIL at the premetastatic niche to promote cancer cell seeding. Sci Adv. 2023;9:eadd5028 pubmed publisher
Koh K, Bonser L, Eckalbar W, Yizhar Barnea O, Shen J, Zeng X, et al. Genomic characterization and therapeutic utilization of IL-13-responsive sequences in asthma. Cell Genom. 2023;3:100229 pubmed publisher
Goldsteen P, Sabogal Guaqueta A, Mulder P, Bos I, Eggens M, van der Koog L, et al. Differentiation and on axon-guidance chip culture of human pluripotent stem cell-derived peripheral cholinergic neurons for airway neurobiology studies. Front Pharmacol. 2022;13:991072 pubmed publisher
Long C, Guo R, Han R, Li K, Wan Y, Xu J, et al. Effects of macrophages on the proliferation and cardiac differentiation of human induced pluripotent stem cells. Cell Commun Signal. 2022;20:108 pubmed publisher
Fonteneau G, Redding A, Hoag Lee H, Sim E, Heinrich S, Gaida M, et al. Stress Granules determine the Development of Obesity-associated Pancreatic Cancer. Cancer Discov. 2022;: pubmed publisher
Rodriguez Perdigon M, Jimaja S, Haeni L, Bruns N, Rothen Rutishauser B, R xfc egg C. Polymersomes-Mediated Delivery of CSF1R Inhibitor to Tumor Associated Macrophages Promotes M2 to M1-Like Macrophage Repolarization. Macromol Biosci. 2022;22:e2200168 pubmed publisher
Hansen L, Yang R, Roso K, Wang W, Chen L, Yang Q, et al. MTAP loss correlates with an immunosuppressive profile in GBM and its substrate MTA stimulates alternative macrophage polarization. Sci Rep. 2022;12:4183 pubmed publisher
Niehues H, Rikken G, van Vlijmen Willems I, Rodijk Olthuis D, van Erp P, Zeeuwen P, et al. Identification of Keratinocyte Mitogens: Implications for Hyperproliferation in Psoriasis and Atopic Dermatitis. JID Innov. 2022;2:100066 pubmed publisher
Li Y, Zhu Y, Feng S, Ishida Y, Chiu T, Saito T, et al. Macrophages activated by hepatitis B virus have distinct metabolic profiles and suppress the virus via IL-1β to downregulate PPARα and FOXO3. Cell Rep. 2022;38:110284 pubmed publisher
Jiang M, Yakupu A, Guan H, Dong J, Liu Y, Song F, et al. Pyridoxamine ameliorates methylglyoxal-induced macrophage dysfunction to facilitate tissue repair in diabetic wounds. Int Wound J. 2022;19:52-63 pubmed publisher
Niyonzima N, Rahman J, Kunz N, West E, Freiwald T, Desai J, et al. Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation. Sci Immunol. 2021;6:eabf2489 pubmed publisher
Bolis M, Bossi D, Vallerga A, Ceserani V, Cavalli M, Impellizzieri D, et al. Dynamic prostate cancer transcriptome analysis delineates the trajectory to disease progression. Nat Commun. 2021;12:7033 pubmed publisher
Ji W, Li D, Wei D, Gu A, Yang Y, Peng J. Cytochrome P450 26A1 Modulates the Polarization of Uterine Macrophages During the Peri-Implantation Period. Front Immunol. 2021;12:763067 pubmed publisher
Le F, Yang L, Han Y, Zhong Y, Zhan F, Feng Y, et al. TPL Inhibits the Invasion and Migration of Drug-Resistant Ovarian Cancer by Targeting the PI3K/AKT/NF-κB-Signaling Pathway to Inhibit the Polarization of M2 TAMs. Front Oncol. 2021;11:704001 pubmed publisher
Liu Y, Du M, Lin H. Histone deacetylase 9 deficiency exaggerates uterine M2 macrophage polarization. J Cell Mol Med. 2021;25:7690-7708 pubmed publisher
Trauelsen M, Hiron T, Lin D, Petersen J, Breton B, Husted A, et al. Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling. Cell Rep. 2021;35:109246 pubmed publisher
Wang Y, Wang X, Yu J, Ma F, Li Z, Zhou Y, et al. Targeting monoamine oxidase A-regulated tumor-associated macrophage polarization for cancer immunotherapy. Nat Commun. 2021;12:3530 pubmed publisher
Conde E, Bertrand R, Balbino B, Bonnefoy J, Stackowicz J, Caillot N, et al. Dual vaccination against IL-4 and IL-13 protects against chronic allergic asthma in mice. Nat Commun. 2021;12:2574 pubmed publisher
Hu J, Wang J, Li C, Shang Y. Fructose-1,6-bisphosphatase aggravates oxidative stress-induced apoptosis in asthma by suppressing the Nrf2 pathway. J Cell Mol Med. 2021;25:5001-5014 pubmed publisher
Gonzalez Figueroa P, Roco J, Papa I, Núñez Villacís L, Stanley M, Linterman M, et al. Follicular regulatory T cells produce neuritin to regulate B cells. Cell. 2021;184:1775-1789.e19 pubmed publisher
Hu G, Su Y, Kang B, Fan Z, Dong T, Brown D, et al. High-throughput phenotypic screen and transcriptional analysis identify new compounds and targets for macrophage reprogramming. Nat Commun. 2021;12:773 pubmed publisher
Sada M, Watanabe M, Inui T, Nakamoto K, Hirata A, Nakamura M, et al. Ruxolitinib inhibits poly(I:C) and type 2 cytokines-induced CCL5 production in bronchial epithelial cells: A potential therapeutic agent for severe eosinophilic asthma. Immun Inflamm Dis. 2021;9:363-373 pubmed publisher
Stephens M, Liao S, von der Weid P. Ultra-purification of Lipopolysaccharides reveals species-specific signalling bias of TLR4: importance in macrophage function. Sci Rep. 2021;11:1335 pubmed publisher
Furlong Silva J, Cross S, Marriott A, Pionnier N, Archer J, Steven A, et al. Tetracyclines improve experimental lymphatic filariasis pathology by disrupting interleukin-4 receptor-mediated lymphangiogenesis. J Clin Invest. 2021;131: pubmed publisher
Zhou F, Liu P, Lv H, Gao Z, Chang W, Xu Y. miR-31 attenuates murine allergic rhinitis by suppressing interleukin-13-induced nasal epithelial inflammatory responses. Mol Med Rep. 2021;23: pubmed publisher
Snodgrass R, Benatzy Y, Schmid T, Namgaladze D, Mainka M, Schebb N, et al. Efferocytosis potentiates the expression of arachidonate 15-lipoxygenase (ALOX15) in alternatively activated human macrophages through LXR activation. Cell Death Differ. 2021;28:1301-1316 pubmed publisher
Povo Retana A, Mojena M, Stremtan A, Fernández García V, Gómez Sáez A, Nuevo Tapioles C, et al. Specific Effects of Trabectedin and Lurbinectedin on Human Macrophage Function and Fate-Novel Insights. Cancers (Basel). 2020;12: pubmed publisher
Skamaki K, Emond S, Chodorge M, Andrews J, Rees D, Cannon D, et al. In vitro evolution of antibody affinity via insertional scanning mutagenesis of an entire antibody variable region. Proc Natl Acad Sci U S A. 2020;117:27307-27318 pubmed publisher
Danahay H, Fox R, Lilley S, Charlton H, Adley K, Christie L, et al. Potentiating TMEM16A does not stimulate airway mucus secretion or bronchial and pulmonary arterial smooth muscle contraction. FASEB Bioadv. 2020;2:464-477 pubmed publisher
Steins A, van Mackelenbergh M, van der Zalm A, Klaassen R, Serrels B, Goris S, et al. High-grade mesenchymal pancreatic ductal adenocarcinoma drives stromal deactivation through CSF-1. EMBO Rep. 2020;21:e48780 pubmed publisher
Draijer C, Speth J, Penke L, Zaslona Z, Bazzill J, Lugogo N, et al. Resident alveolar macrophage-derived vesicular SOCS3 dampens allergic airway inflammation. FASEB J. 2020;34:4718-4731 pubmed publisher
Leite D, Zvar Baskovic B, Civita P, Neto C, Gumbleton M, Pilkington G. A human co-culture cell model incorporating microglia supports glioblastoma growth and migration, and confers resistance to cytotoxics. FASEB J. 2020;34:1710-1727 pubmed publisher
Arlt A, von Bonin F, Rehberg T, Perez Rubio P, Engelmann J, Limm K, et al. High CD206 levels in Hodgkin lymphoma-educated macrophages are linked to matrix-remodeling and lymphoma dissemination. Mol Oncol. 2020;14:571-589 pubmed publisher
Cheng L, Kong C, Walvoort M, Faas M, De Vos P. Human Milk Oligosaccharides Differently Modulate Goblet Cells Under Homeostatic, Proinflammatory Conditions and ER Stress. Mol Nutr Food Res. 2020;64:e1900976 pubmed publisher
Biswas S, Mandal G, Roy Chowdhury S, Purohit S, Payne K, Anadon C, et al. Exosomes Produced by Mesenchymal Stem Cells Drive Differentiation of Myeloid Cells into Immunosuppressive M2-Polarized Macrophages in Breast Cancer. J Immunol. 2019;203:3447-3460 pubmed publisher
Ali M, Mori M, Mertens T, Siddhuraj P, Erjefalt J, Onnerfjord P, et al. Osteopontin Expression in Small Airway Epithelium in Copd is Dependent on Differentiation and Confined to Subsets of Cells. Sci Rep. 2019;9:15566 pubmed publisher
Chen Q, Wang J, Zhang Q, Zhang J, Lou Y, Yang J, et al. Tumour cell-derived debris and IgG synergistically promote metastasis of pancreatic cancer by inducing inflammation via tumour-associated macrophages. Br J Cancer. 2019;121:786-795 pubmed publisher
Ko J, Mills T, Huang J, Chen N, Mertens T, Collum S, et al. Transforming growth factor β1 alters the 3'-UTR of mRNA to promote lung fibrosis. J Biol Chem. 2019;294:15781-15794 pubmed publisher
Lara Reyna S, Scambler T, Holbrook J, Wong C, Jarosz Griffiths H, Martinon F, et al. Metabolic Reprograming of Cystic Fibrosis Macrophages via the IRE1α Arm of the Unfolded Protein Response Results in Exacerbated Inflammation. Front Immunol. 2019;10:1789 pubmed publisher
Fang R, Uchiyama R, Sakai S, Hara H, Tsutsui H, Suda T, et al. ASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanism. Mucosal Immunol. 2019;: pubmed publisher
Canete P, Sweet R, Gonzalez Figueroa P, Papa I, Ohkura N, Bolton H, et al. Regulatory roles of IL-10-producing human follicular T cells. J Exp Med. 2019;: pubmed publisher
Dimou P, Wright R, Budge K, Midgley A, Satchell S, Peak M, et al. The human glomerular endothelial cells are potent pro-inflammatory contributors in an in vitro model of lupus nephritis. Sci Rep. 2019;9:8348 pubmed publisher
Mazzoldi E, Pavan S, Pilotto G, Leone K, Pagotto A, Frezzini S, et al. A juxtacrine/paracrine loop between C-Kit and stem cell factor promotes cancer stem cell survival in epithelial ovarian cancer. Cell Death Dis. 2019;10:412 pubmed publisher
Dong N, Shi X, Wang S, Gao Y, Kuang Z, Xie Q, et al. M2 macrophages mediate sorafenib resistance by secreting HGF in a feed-forward manner in hepatocellular carcinoma. Br J Cancer. 2019;: pubmed publisher
Kim J, Jung K, Kim J, Kim S, Park H, Kim Y. Engineering of anti-human interleukin-4 receptor alpha antibodies with potent antagonistic activity. Sci Rep. 2019;9:7772 pubmed publisher
Wei Y, Ma R, Zhang J, Wu X, Yu G, Hu X, et al. Excessive periostin expression and Th2 response in patients with nasal polyps: association with asthma. J Thorac Dis. 2018;10:6585-6597 pubmed publisher
Barrios J, Kho A, Aven L, Mitchel J, Park J, Randell S, et al. Pulmonary Neuroendocrine Cells Secrete GABA to Induce Goblet Cell Hyperplasia in Primate Models. Am J Respir Cell Mol Biol. 2018;: pubmed publisher
Namgaladze D, Zukunft S, Schnütgen F, Kurrle N, Fleming I, Fuhrmann D, et al. Polarization of Human Macrophages by Interleukin-4 Does Not Require ATP-Citrate Lyase. Front Immunol. 2018;9:2858 pubmed publisher
Otsuka Y, Watanabe E, Shinya E, Okura S, Saeki H, Geijtenbeek T, et al. Differentiation of Langerhans Cells from Monocytes and Their Specific Function in Inducing IL-22-Specific Th Cells. J Immunol. 2018;201:3006-3016 pubmed publisher
Wang Y, Wu Y, Hung C, Wang S, Young M, Hsu T, et al. USP24 induces IL-6 in tumor-associated microenvironment by stabilizing p300 and β-TrCP and promotes cancer malignancy. Nat Commun. 2018;9:3996 pubmed publisher
Wang N, Liu W, Zheng Y, Wang S, Yang B, Li M, et al. CXCL1 derived from tumor-associated macrophages promotes breast cancer metastasis via activating NF-?B/SOX4 signaling. Cell Death Dis. 2018;9:880 pubmed publisher
Plugis N, Weng N, Zhao Q, Palanski B, Maecker H, Habtezion A, et al. Interleukin 4 is inactivated via selective disulfide-bond reduction by extracellular thioredoxin. Proc Natl Acad Sci U S A. 2018;115:8781-8786 pubmed publisher
Mitamura Y, Nunomura S, Nanri Y, Arima K, Yoshihara T, Komiya K, et al. Hierarchical control of interleukin 13 (IL-13) signals in lung fibroblasts by STAT6 and SOX11. J Biol Chem. 2018;293:14646-14658 pubmed publisher
Sherrill J, Kc K, Wang X, Wen T, Chamberlin A, Stucke E, et al. Whole-exome sequencing uncovers oxidoreductases DHTKD1 and OGDHL as linkers between mitochondrial dysfunction and eosinophilic esophagitis. JCI Insight. 2018;3: pubmed publisher
Zhang W, Kim H, Lv J, Zhao N, Ma X. Golgi Phosphoprotein 2 Is a Novel Regulator of IL-12 Production and Macrophage Polarization. J Immunol. 2018;200:1480-1488 pubmed publisher
Travers J, Rochman M, Caldwell J, Besse J, Miracle C, Rothenberg M. IL-33 is induced in undifferentiated, non-dividing esophageal epithelial cells in eosinophilic esophagitis. Sci Rep. 2017;7:17563 pubmed publisher
Newman J, Wang G, Arima K, Guan S, Waters M, Cavenee W, et al. Interleukin-13 receptor alpha 2 cooperates with EGFRvIII signaling to promote glioblastoma multiforme. Nat Commun. 2017;8:1913 pubmed publisher
Chassin H, Geering B, Schukur L, Ausländer D, Lang B, Fussenegger M. Sensing and responding to allergic response cytokines through a genetically encoded circuit. Nat Commun. 2017;8:1101 pubmed publisher
Mertens T, van der Does A, Kistemaker L, Ninaber D, Taube C, Hiemstra P. Cigarette smoke differentially affects IL-13-induced gene expression in human airway epithelial cells. Physiol Rep. 2017;5: pubmed publisher
Chu M, Ji J, Cao W, Zhang H, Meng D, Xie B, et al. Cyclic peptide *CRRETAWAC* attenuates fibronectin-induced cytokine secretion of human airway smooth muscle cells by inhibiting FAK and p38 MAPK. J Cell Mol Med. 2017;21:2535-2541 pubmed publisher
Zhu Z, Ding J, Ma Z, Iwashina T, Tredget E. Alternatively activated macrophages derived from THP-1 cells promote the fibrogenic activities of human dermal fibroblasts. Wound Repair Regen. 2017;25:377-388 pubmed publisher
Wang X, Yang X, Li Y, Wang X, Zhang Y, Dai X, et al. Lyn kinase represses mucus hypersecretion by regulating IL-13-induced endoplasmic reticulum stress in asthma. EBioMedicine. 2017;15:137-149 pubmed publisher
Wong C, Bezhaeva T, Rothuizen T, Metselaar J, De Vries M, Verbeek F, et al. Liposomal prednisolone inhibits vascular inflammation and enhances venous outward remodeling in a murine arteriovenous fistula model. Sci Rep. 2016;6:30439 pubmed publisher
Guo B, Zhang L, Chiorazzi N, Rothstein T. IL-4 rescues surface IgM expression in chronic lymphocytic leukemia. Blood. 2016;128:553-62 pubmed publisher
Li C, Levin M, Kaplan D. Bioelectric modulation of macrophage polarization. Sci Rep. 2016;6:21044 pubmed publisher
Su S, Zhao Q, He C, Huang D, Liu J, Chen F, et al. miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program. Nat Commun. 2015;6:8523 pubmed publisher
Gerovac B, Fregien N. IL-13 Inhibits Multicilin Expression and Ciliogenesis via Janus Kinase/Signal Transducer and Activator of Transcription Independently of Notch Cleavage. Am J Respir Cell Mol Biol. 2016;54:554-61 pubmed publisher
Takei K, Mitoma C, Hashimoto Hachiya A, Takahara M, Tsuji G, Nakahara T, et al. Galactomyces fermentation filtrate prevents T helper 2-mediated reduction of filaggrin in an aryl hydrocarbon receptor-dependent manner. Clin Exp Dermatol. 2015;40:786-93 pubmed publisher
Geskin L, Viragova S, Stolz D, Fuschiotti P. Interleukin-13 is overexpressed in cutaneous T-cell lymphoma cells and regulates their proliferation. Blood. 2015;125:2798-805 pubmed publisher
Li J, Razumilava N, Gores G, Walters S, Mizuochi T, Mourya R, et al. Biliary repair and carcinogenesis are mediated by IL-33-dependent cholangiocyte proliferation. J Clin Invest. 2014;124:3241-51 pubmed publisher
Lim E, Rothenberg M. Demethylation of the human eotaxin-3 gene promoter leads to the elevated expression of eotaxin-3. J Immunol. 2014;192:466-74 pubmed publisher
Chang H, Miaw S, Tseng W, Sun Y, Liu C, Tsao H, et al. PTPN22 modulates macrophage polarization and susceptibility to dextran sulfate sodium-induced colitis. J Immunol. 2013;191:2134-43 pubmed publisher
Rawal S, Chu F, Zhang M, Park H, Nattamai D, Kannan S, et al. Cross talk between follicular Th cells and tumor cells in human follicular lymphoma promotes immune evasion in the tumor microenvironment. J Immunol. 2013;190:6681-93 pubmed publisher
Parker J, Thavagnanam S, Skibinski G, Lyons J, Bell J, Heaney L, et al. Chronic IL9 and IL-13 exposure leads to an altered differentiation of ciliated cells in a well-differentiated paediatric bronchial epithelial cell model. PLoS ONE. 2013;8:e61023 pubmed publisher
Alevy Y, Patel A, Romero A, Patel D, Tucker J, Roswit W, et al. IL-13-induced airway mucus production is attenuated by MAPK13 inhibition. J Clin Invest. 2012;122:4555-68 pubmed publisher
Mariante R, N xf3 brega A, Martins R, Areal R, Bellio M, Linden R. Neuroimmunoendocrine regulation of the prion protein in neutrophils. J Biol Chem. 2012;287:35506-35515 pubmed publisher
Masuoka M, Shiraishi H, Ohta S, Suzuki S, Arima K, Aoki S, et al. Periostin promotes chronic allergic inflammation in response to Th2 cytokines. J Clin Invest. 2012;122:2590-600 pubmed publisher
Suh H, Choi N, Tarassishin L, Lee S. Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12). PLoS ONE. 2012;7:e35115 pubmed publisher
Comas Casellas E, Martinez Barriocanal A, Miro F, Ejarque Ortiz A, Schwartz S, Martin M, et al. Cloning and characterization of CD300d, a novel member of the human CD300 family of immune receptors. J Biol Chem. 2012;287:9682-93 pubmed publisher
Jackson S, Holloway J, Warner J, Sampson A. Interleukin-13, but not indomethacin, increases cysteinyl-leukotriene synthesis in human lung macrophages. J Allergy (Cairo). 2012;2012:348741 pubmed publisher
Maharjan A, Pilling D, Gomer R. High and low molecular weight hyaluronic acid differentially regulate human fibrocyte differentiation. PLoS ONE. 2011;6:e26078 pubmed publisher
Chen H, Sun H, You F, Sun W, Zhou X, Chen L, et al. Activation of STAT6 by STING is critical for antiviral innate immunity. Cell. 2011;147:436-46 pubmed publisher
Svensson J, Jenmalm M, Matussek A, Geffers R, Berg G, Ernerudh J. Macrophages at the fetal-maternal interface express markers of alternative activation and are induced by M-CSF and IL-10. J Immunol. 2011;187:3671-82 pubmed publisher
Jiang D, Perelman J, Kolosov V, Zhou X. Effects of scutellarin on MUC5AC mucin production induced by human neutrophil elastase or interleukin 13 on airway epithelial cells. J Korean Med Sci. 2011;26:778-84 pubmed publisher
Zuyderduyn S, Ninaber D, Schrumpf J, van Sterkenburg M, Verhoosel R, Prins F, et al. IL-4 and IL-13 exposure during mucociliary differentiation of bronchial epithelial cells increases antimicrobial activity and expression of antimicrobial peptides. Respir Res. 2011;12:59 pubmed publisher
Lim E, Lu T, Blanchard C, Rothenberg M. Epigenetic regulation of the IL-13-induced human eotaxin-3 gene by CREB-binding protein-mediated histone 3 acetylation. J Biol Chem. 2011;286:13193-204 pubmed publisher
Kis L, Gerasimcik N, Salamon D, Persson E, Nagy N, Klein G, et al. STAT6 signaling pathway activated by the cytokines IL-4 and IL-13 induces expression of the Epstein-Barr virus-encoded protein LMP-1 in absence of EBNA-2: implications for the type II EBV latent gene expression in Hodgkin lymphoma. Blood. 2011;117:165-74 pubmed publisher
Macey M, Sturgill J, Morales J, Falanga Y, Morales J, Norton S, et al. IL-4 and TGF-beta 1 counterbalance one another while regulating mast cell homeostasis. J Immunol. 2010;184:4688-95 pubmed publisher
Blanchard C, Stucke E, Burwinkel K, Caldwell J, Collins M, Ahrens A, et al. Coordinate interaction between IL-13 and epithelial differentiation cluster genes in eosinophilic esophagitis. J Immunol. 2010;184:4033-41 pubmed publisher
Chen W, Sivaprasad U, Tabata Y, Gibson A, Stier M, Finkelman F, et al. IL-13R alpha 2 membrane and soluble isoforms differ in humans and mice. J Immunol. 2009;183:7870-6 pubmed publisher
Suryani S, Fulcher D, Santner Nanan B, Nanan R, Wong M, Shaw P, et al. Differential expression of CD21 identifies developmentally and functionally distinct subsets of human transitional B cells. Blood. 2010;115:519-29 pubmed publisher
Godin Ethier J, Pelletier S, Hanafi L, Gannon P, Forget M, Routy J, et al. Human activated T lymphocytes modulate IDO expression in tumors through Th1/Th2 balance. J Immunol. 2009;183:7752-60 pubmed publisher
Kurowska Stolarska M, Stolarski B, Kewin P, Murphy G, Corrigan C, Ying S, et al. IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammation. J Immunol. 2009;183:6469-77 pubmed publisher
Van den Bossche J, Bogaert P, van Hengel J, Guerin C, Berx G, Movahedi K, et al. Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes. Blood. 2009;114:4664-74 pubmed publisher
Martin C, Kurkowski D, Valentino A, Santiago Schwarz F. Increased intracellular, cell surface, and secreted inducible heat shock protein 70 responses are triggered during the monocyte to dendritic cell (DC) transition by cytokines independently of heat stress and infection and may positively regulate DC g. J Immunol. 2009;183:388-99 pubmed publisher
Darcan Nicolaisen Y, Meinicke H, Fels G, Hegend O, Haberland A, Kühl A, et al. Small interfering RNA against transcription factor STAT6 inhibits allergic airway inflammation and hyperreactivity in mice. J Immunol. 2009;182:7501-8 pubmed publisher
ZHONG C, Qu X, Tan M, Meng Y, Ferrara N. Characterization and regulation of bv8 in human blood cells. Clin Cancer Res. 2009;15:2675-84 pubmed publisher
Zeeuwen P, de Jongh G, Rodijk Olthuis D, Kamsteeg M, Verhoosel R, van Rossum M, et al. Genetically programmed differences in epidermal host defense between psoriasis and atopic dermatitis patients. PLoS ONE. 2008;3:e2301 pubmed publisher
Mackinnon A, Farnworth S, Hodkinson P, Henderson N, Atkinson K, Leffler H, et al. Regulation of alternative macrophage activation by galectin-3. J Immunol. 2008;180:2650-8 pubmed
Cassatella M, Pereira da Silva G, da Silva G, Tinazzi I, Facchetti F, Scapini P, et al. Soluble TNF-like cytokine (TL1A) production by immune complexes stimulated monocytes in rheumatoid arthritis. J Immunol. 2007;178:7325-33 pubmed
Good K, Bryant V, Tangye S. Kinetics of human B cell behavior and amplification of proliferative responses following stimulation with IL-21. J Immunol. 2006;177:5236-47 pubmed
Chen W, Ericksen M, Levin L, Khurana Hershey G. Functional effect of the R110Q IL13 genetic variant alone and in combination with IL4RA genetic variants. J Allergy Clin Immunol. 2004;114:553-60 pubmed
Lin L, Gerth A, Peng S. Active inhibition of plasma cell development in resting B cells by microphthalmia-associated transcription factor. J Exp Med. 2004;200:115-22 pubmed
Pilette C, Francis J, Till S, Durham S. CCR4 ligands are up-regulated in the airways of atopic asthmatics after segmental allergen challenge. Eur Respir J. 2004;23:876-84 pubmed
Hemminki A, Kanerva A, Liu B, Wang M, Alvarez R, Siegal G, et al. Modulation of coxsackie-adenovirus receptor expression for increased adenoviral transgene expression. Cancer Res. 2003;63:847-53 pubmed
Wang J, Guan E, Roderiquez G, Calvert V, Alvarez R, Norcross M. Role of tyrosine phosphorylation in ligand-independent sequestration of CXCR4 in human primary monocytes-macrophages. J Biol Chem. 2001;276:49236-43 pubmed
product information
Product Type :
Protein
Product Name :
Human IL-13 Recombinant Protein, PeproTech
Catalog # :
200-13-10UG
Quantity :
10 ug
Price :
US 226.00
Clonality :
Recombinant
Purity :
purified
Reactivity :
Human
Applications :
ELISA: Assay-dependent, Functional Assay: Assay-dependent, Western Blot: Assay-dependent
Species :
Human
Storage :
-20 C
Description :
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.
Format :
Lyophilized
Applications w/Dilutions :
ELISA: Assay-dependent, Functional Assay: Assay-dependent, Western Blot: Assay-dependent
Aliases :
ALRH; ALRH antibody; BHR1; il 13; Il13; Il-13; IL-13; cytokine; ILN; Interleukin; interleukin 13; Interleukin13; interleukin-13; interleukin-13 precursor; L13; MGC116786; MGC116788; MGC116789; NC30; NC30 antibody; P600; P600 antibody; T-cell activation protein P600
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA