| Reference |
|---|
Xie X, Gou F, Zheng Z, Zhang Y, Zhang Y, Dong F, et al. Decoding human bone marrow hematopoietic stem and progenitor cells from fetal to birth. iScience. 2024;27:110445 pubmed publisher |
Albanese M, Chen H, Gapp M, Muenchhoff M, Yang H, Peterhoff D, et al. Receptor transfer between immune cells by autoantibody-enhanced, CD32-driven trogocytosis is hijacked by HIV-1 to infect resting CD4 T cells. Cell Rep Med. 2024;5:101483 pubmed publisher |
Fowler J, Zheng S, Nguyen A, Chen A, Xiong X, Chai T, et al. Lineage-tracing hematopoietic stem cell origins in vivo to efficiently make human HLF+ HOXA+ hematopoietic progenitors from pluripotent stem cells. Dev Cell. 2024;59:1110-1131.e22 pubmed publisher |
Mandal K, Wicaksono G, Yu C, Adams J, Hoopmann M, Temple W, et al. Structural surfaceomics reveals an AML-specific conformation of integrin β2 as a CAR T cellular therapy target. Nat Cancer. 2023;4:1592-1609 pubmed publisher |
Li Y, Ochoa C, Zhu Y, Kramer A, Wilson M, Fang Y, et al. Profiling ovarian cancer tumor and microenvironment during disease progression for cell-based immunotherapy design. iScience. 2023;26:107952 pubmed publisher |
Casirati G, Cosentino A, Mucci A, Salah Mahmoud M, Ugarte Zabala I, Zeng J, et al. Epitope editing enables targeted immunotherapy of acute myeloid leukaemia. Nature. 2023;621:404-414 pubmed publisher |
Jung H, Suknuntha K, Kim Y, Liu P, Dettle S, Sedzro D, et al. SOX18-enforced expression diverts hemogenic endothelium-derived progenitors from T towards NK lymphoid pathways. iScience. 2023;26:106621 pubmed publisher |
Shiqi L, Jiasi Z, Lvzhe C, Huailong X, Liping H, Lin L, et al. Durable remission related to CAR-T persistence in R/R B-ALL and long-term persistence potential of prime CAR-T. Mol Ther Oncolytics. 2023;29:107-117 pubmed publisher |
Wang W, Li X, Qin X, Miao Y, Zhang Y, Li S, et al. Germline Neurofibromin 1 mutation enhances the anti-tumour immune response and decreases juvenile myelomonocytic leukaemia tumourigenicity. Br J Haematol. 2023;202:328-343 pubmed publisher |
Moon J, Younis S, Ramadoss N, Iyer R, Sheth K, Sharpe O, et al. Cytotoxic CD8+ T cells target citrullinated antigens in rheumatoid arthritis. Nat Commun. 2023;14:319 pubmed publisher |
Liu X, Sato N, Yabushita T, Li J, Jia Y, Tamura M, et al. IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia. EMBO Mol Med. 2022;:e15631 pubmed publisher |
Parry N, Busch C, A xdf mann V, Cassels J, Hair A, Helgason G, et al. BH3 mimetics in combination with nilotinib or ponatinib represent a promising therapeutic strategy in blast phase chronic myeloid leukemia. Cell Death Discov. 2022;8:457 pubmed publisher |
Lee M, Geitgey D, Hamilton J, Boss J, Scharer C, Spangle J, et al. Adipocyte-mediated epigenomic instability in human T-ALL cells is cytotoxic and phenocopied by epigenetic-modifying drugs. Front Cell Dev Biol. 2022;10:909557 pubmed publisher |
Li Y, Zeng S, Dunn Z, Zhou Y, Li Z, Yu J, et al. Off-the-shelf third-party HSC-engineered iNKT cells for ameliorating GvHD while preserving GvL effect in the treatment of blood cancers. iScience. 2022;25:104859 pubmed publisher |
Yu G, Wang W, He X, Xu J, Xu R, Wan T, et al. Synergistic Therapeutic Effects of Low Dose Decitabine and NY-ESO-1 Specific TCR-T Cells for the Colorectal Cancer With Microsatellite Stability. Front Oncol. 2022;12:895103 pubmed publisher |
Nystrom S, Li G, Datta S, Soldano K, Silas D, Weins A, et al. JAK inhibitor blocks COVID-19 cytokine-induced JAK/STAT/APOL1 signaling in glomerular cells and podocytopathy in human kidney organoids. JCI Insight. 2022;7: pubmed publisher |
Giles J, Manne S, Freilich E, Oldridge D, Baxter A, George S, et al. Human epigenetic and transcriptional T cell differentiation atlas for identifying functional T cell-specific enhancers. Immunity. 2022;55:557-574.e7 pubmed publisher |
Hebbar N, Epperly R, Vaidya A, Thanekar U, Moore S, Umeda M, et al. CAR T cells redirected to cell surface GRP78 display robust anti-acute myeloid leukemia activity and do not target hematopoietic progenitor cells. Nat Commun. 2022;13:587 pubmed publisher |
Broderick L, Clay G, Blum R, Liu Y, McVicar R, Papes F, et al. Disease-associated mutations in topoisomerase IIβ result in defective NK cells. J Allergy Clin Immunol. 2022;149:2171-2176.e3 pubmed publisher |
Liu G, Chen Y, Wang Y, Deng X, Xiao Q, Zhang L, et al. Angiotensin II enhances group 2 innate lymphoid cell responses via AT1a during airway inflammation. J Exp Med. 2022;219: pubmed publisher |
Banskota S, Raguram A, Suh S, Du S, Davis J, Choi E, et al. Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins. Cell. 2022;185:250-265.e16 pubmed publisher |
Moosmann C, Müller T, Busch D, Schober K. Orthotopic T-cell receptor replacement in primary human T cells using CRISPR-Cas9-mediated homology-directed repair. STAR Protoc. 2022;3:101031 pubmed publisher |
Albanese M, Ruhle A, Mittermaier J, Mejías Pérez E, Gapp M, Linder A, et al. Rapid, efficient and activation-neutral gene editing of polyclonal primary human resting CD4+ T cells allows complex functional analyses. Nat Methods. 2022;19:81-89 pubmed publisher |
Oburoglu L, Mansell E, Canals I, Sigurdsson V, Guibentif C, Soneji S, et al. Pyruvate metabolism guides definitive lineage specification during hematopoietic emergence. EMBO Rep. 2022;23:e54384 pubmed publisher |
Stairiker C, Pfister S, Hendrickson E, Yang W, Xie T, Lee C, et al. EZH2 Inhibition Compromises α4-1BB-Mediated Antitumor Efficacy by Reducing the Survival and Effector Programming of CD8+ T Cells. Front Immunol. 2021;12:770080 pubmed publisher |
Deng B, Pan J, Liu Z, Liu S, Chen Y, Qu X, et al. Peripheral leukemia burden at time of apheresis negatively affects the clinical efficacy of CART19 in refractory or relapsed B-ALL. Mol Ther Methods Clin Dev. 2021;23:633-643 pubmed publisher |
Li Y, Zhou Y, Kim Y, Zhu Y, Ma F, Yu J, et al. Development of allogeneic HSC-engineered iNKT cells for off-the-shelf cancer immunotherapy. Cell Rep Med. 2021;2:100449 pubmed publisher |
Rice S, Jackson T, Crump N, Fordham N, Elliott N, O Byrne S, et al. A human fetal liver-derived infant MLL-AF4 acute lymphoblastic leukemia model reveals a distinct fetal gene expression program. Nat Commun. 2021;12:6905 pubmed publisher |
Rotolo A, Atherton M, Kasper B, Haran K, Mason N. Genetic re-direction of canine primary T cells for clinical trial use in pet dogs with spontaneous cancer. STAR Protoc. 2021;2:100905 pubmed publisher |
Hirabayashi K, Du H, Xu Y, Shou P, Zhou X, Fuc xe1 G, et al. Dual Targeting CAR-T Cells with Optimal Costimulation and Metabolic Fitness enhance Antitumor Activity and Prevent Escape in Solid Tumors. Nat Cancer. 2021;2:904-918 pubmed publisher |
Wang Z, Ran L, Chen C, Shi R, Dong Y, Li Y, et al. Identification of HLA-A2-Restricted Mutant Epitopes from Neoantigens of Esophageal Squamous Cell Carcinoma. Vaccines (Basel). 2021;9: pubmed publisher |
Chen P, Hussmann J, Yan J, Knipping F, Ravisankar P, Chen P, et al. Enhanced prime editing systems by manipulating cellular determinants of editing outcomes. Cell. 2021;184:5635-5652.e29 pubmed publisher |
Zebley C, Abdelsamed H, Ghoneim H, Alli S, Brown C, Haydar D, et al. Proinflammatory cytokines promote TET2-mediated DNA demethylation during CD8 T cell effector differentiation. Cell Rep. 2021;37:109796 pubmed publisher |
Haeseleer F, Fukazawa Y, Park H, Varco Merth B, Rust B, Smedley J, et al. Immune inactivation of anti-simian immunodeficiency virus chimeric antigen receptor T cells in rhesus macaques. Mol Ther Methods Clin Dev. 2021;22:304-319 pubmed publisher |
Eberhardt C, Kissick H, Patel M, Cardenas M, Prokhnevska N, Obeng R, et al. Functional HPV-specific PD-1+ stem-like CD8 T cells in head and neck cancer. Nature. 2021;597:279-284 pubmed publisher |
Müller T, Jarosch S, Hammel M, Leube J, Grassmann S, Bernard B, et al. Targeted T cell receptor gene editing provides predictable T cell product function for immunotherapy. Cell Rep Med. 2021;2:100374 pubmed publisher |
Lulu A, Cummings K, Jeffery E, Myers P, Underwood D, Lacy R, et al. Characteristics of Immune Memory and Effector Activity to Cancer-Expressed MHC Class I Phosphopeptides Differ in Healthy Donors and Ovarian Cancer Patients. Cancer Immunol Res. 2021;9:1327-1341 pubmed publisher |
Klaeger S, Apffel A, Clauser K, Sarkizova S, Oliveira G, Rachimi S, et al. Optimized Liquid and Gas Phase Fractionation Increases HLA-Peptidome Coverage for Primary Cell and Tissue Samples. Mol Cell Proteomics. 2021;20:100133 pubmed publisher |
Qiu J, Zhang J, Ji Y, Sun H, Gu Z, Sun Q, et al. Tissue signals imprint Aiolos expression in ILC2s to modulate type 2 immunity. Mucosal Immunol. 2021;14:1306-1322 pubmed publisher |
Kim H, Kim J, Seol B, Song C, Jeong J, Cho Y. Directly reprogrammed natural killer cells for cancer immunotherapy. Nat Biomed Eng. 2021;5:1360-1376 pubmed publisher |
Seo I, Eun H, Kim J, Lee H, Jeong S, Choi S, et al. IL-15 enhances CCR5-mediated migration of memory CD8+ T cells by upregulating CCR5 expression in the absence of TCR stimulation. Cell Rep. 2021;36:109438 pubmed publisher |
Sivapalan R, Liu J, Chakraborty K, Arthofer E, Choudhry M, Barie P, et al. Virus Induced Lymphocytes (VIL) as a novel viral antigen-specific T cell therapy for COVID-19 and potential future pandemics. Sci Rep. 2021;11:15295 pubmed publisher |
Fischer D, Ansari M, Wagner K, Jarosch S, Huang Y, Mayr C, et al. Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through 'reverse phenotyping'. Nat Commun. 2021;12:4515 pubmed publisher |
Shen C, Liu C, Zhang Z, Ping Y, Shao J, Tian Y, et al. PD-1 Affects the Immunosuppressive Function of Group 2 Innate Lymphoid Cells in Human Non-Small Cell Lung Cancer. Front Immunol. 2021;12:680055 pubmed publisher |
Soni M, Migliori E, Assal A, Chan H, Ciubotariu R, Pan J, et al. Development of T-cell immunity in a liver and hematopoietic stem cell transplant recipient following coronavirus disease 2019 infection. Cytotherapy. 2021;23:980-984 pubmed publisher |
O Sullivan D, Stanczak M, Villa M, Uhl F, Corrado M, Klein Geltink R, et al. Fever supports CD8+ effector T cell responses by promoting mitochondrial translation. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher |
Portillo A, Hogg R, Poznanski S, Rojas E, Cashell N, Hammill J, et al. Expanded human NK cells armed with CAR uncouple potent anti-tumor activity from off-tumor toxicity against solid tumors. iScience. 2021;24:102619 pubmed publisher |
Ma Y, Ou J, Lin T, Chen L, Chen J, Wang M. Next Generation Sequencing-Based Identification of T-Cell Receptors for Immunotherapy Against Hepatocellular Carcinoma. Hepatol Commun. 2021;5:1106-1119 pubmed publisher |
Moirangthem R, Ma K, Lizot S, Cordesse A, Olivr xe9 J, de Chappedelaine C, et al. A DL-4- and TNFα-based culture system to generate high numbers of nonmodified or genetically modified immunotherapeutic human T-lymphoid progenitors. Cell Mol Immunol. 2021;18:1662-1676 pubmed publisher |
Ito T, Kawai Y, Yasui Y, Iriguchi S, Minagawa A, Ishii T, et al. The therapeutic potential of multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-1derived iPS cells. Commun Biol. 2021;4:694 pubmed publisher |
Wilhelm M, Zolg D, Graber M, Gessulat S, Schmidt T, Schnatbaum K, et al. Deep learning boosts sensitivity of mass spectrometry-based immunopeptidomics. Nat Commun. 2021;12:3346 pubmed publisher |
Lee H, Jung O, Hennighausen L. JAK inhibitors dampen activation of interferon-stimulated transcription of ACE2 isoforms in human airway epithelial cells. Commun Biol. 2021;4:654 pubmed publisher |
Pan Y, Aiamkitsumrit B, Bartolo L, Wang Y, Lavery C, Marc A, et al. Vaccination reshapes the virus-specific T cell repertoire in unexposed adults. Immunity. 2021;54:1245-1256.e5 pubmed publisher |
Schmidt N, Wing P, Diniz M, Pallett L, Swadling L, Harris J, et al. Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint. Nat Commun. 2021;12:2814 pubmed publisher |
Wang K, Chen Y, Ahn S, Zheng M, Landoni E, Dotti G, et al. GD2-specific CAR T cells encapsulated in an injectable hydrogel control retinoblastoma and preserve vision. Nat Cancer. 2020;1:990-997 pubmed publisher |
Platten M, Bunse L, Wick A, Bunse T, Le Cornet L, Harting I, et al. A vaccine targeting mutant IDH1 in newly diagnosed glioma. Nature. 2021;592:463-468 pubmed publisher |
Ehx G, Larouche J, Durette C, Laverdure J, Hesnard L, Vincent K, et al. Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes. Immunity. 2021;54:737-752.e10 pubmed publisher |
Reid J, Golubeva D, Boyd A, Hollands C, Henly C, Orlando L, et al. Human pluripotent stem cells identify molecular targets of trisomy 12 in chronic lymphocytic leukemia patients. Cell Rep. 2021;34:108845 pubmed publisher |
Zheng W, Wei J, Zebley C, Jones L, Dhungana Y, Wang Y, et al. Regnase-1 suppresses TCF-1+ precursor exhausted T-cell formation to limit CAR-T-cell responses against ALL. Blood. 2021;138:122-135 pubmed publisher |
Herda S, Heimann A, Obermayer B, Ciraolo E, Althoff S, Ru xdf J, et al. Long-term in vitro expansion ensures increased yield of central memory T cells as perspective for manufacturing challenges. Int J Cancer. 2021;148:3097-3110 pubmed publisher |
Jung H, Uenishi G, Park M, Liu P, Suknuntha K, Raymond M, et al. SOX17 integrates HOXA and arterial programs in hemogenic endothelium to drive definitive lympho-myeloid hematopoiesis. Cell Rep. 2021;34:108758 pubmed publisher |
Kazuki Y, Uno N, Abe S, Kajitani N, Kazuki K, Yakura Y, et al. Engineering of human induced pluripotent stem cells via human artificial chromosome vectors for cell therapy and disease modeling. Mol Ther Nucleic Acids. 2021;23:629-639 pubmed publisher |
Galat Y, Gu H, Perepitchka M, Taylor R, Yoon J, Glukhova X, et al. Crispr editing of the gli1 first intron abrogates gli1 expression and differentially alters lineage commitment. Stem Cells. 2021;: pubmed publisher |
Vavassori V, Mercuri E, Marcovecchio G, Castiello M, Schiroli G, Albano L, et al. Modeling, optimization, and comparable efficacy of T cell and hematopoietic stem cell gene editing for treating hyper-IgM syndrome. EMBO Mol Med. 2021;13:e13545 pubmed publisher |
Golebski K, Layhadi J, Sahiner U, Steveling Klein E, Lenormand M, Li R, et al. Induction of IL-10-producing type 2 innate lymphoid cells by allergen immunotherapy is associated with clinical response. Immunity. 2021;54:291-307.e7 pubmed publisher |
Olariu V, Yui M, Krupinski P, Zhou W, Deichmann J, Andersson E, et al. Multi-scale Dynamical Modeling of T Cell Development from an Early Thymic Progenitor State to Lineage Commitment. Cell Rep. 2021;34:108622 pubmed publisher |
Louka E, Povinelli B, Rodriguez Meira A, Buck G, Wen W, Wang G, et al. Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia. J Exp Med. 2021;218: pubmed publisher |
Xu N, Palmer D, Robeson A, Shou P, Bommiasamy H, Laurie S, et al. STING agonist promotes CAR T cell trafficking and persistence in breast cancer. J Exp Med. 2021;218: pubmed publisher |
Sujjitjoon J, Sayour E, Tsao S, Uiprasertkul M, Sanpakit K, Buaboonnam J, et al. GD2-specific chimeric antigen receptor-modified T cells targeting retinoblastoma - assessing tumor and T cell interaction. Transl Oncol. 2021;14:100971 pubmed publisher |
Tremblay C, Chiu S, Saw J, McCalmont H, Litalien V, Boyle J, et al. Small molecule inhibition of Dynamin-dependent endocytosis targets multiple niche signals and impairs leukemia stem cells. Nat Commun. 2020;11:6211 pubmed publisher |
Perry N, Wasko K, Cheng J, Tabbaa D, Marco E, Giannoukos G, et al. Methylation-Sensitive Restriction Enzyme Quantitative Polymerase Chain Reaction Enables Rapid, Accurate, and Precise Detection of Methylation Status of the Regulatory T Cell (Treg)-Specific Demethylation Region in Primary Human Tregs. J Immunol. 2021;206:446-451 pubmed publisher |
Harro C, Perez Sanz J, Costich T, Payne K, Anadon C, Chaurio R, et al. Methyltransferase inhibitors restore SATB1 protective activity against cutaneous T cell lymphoma in mice. J Clin Invest. 2021;131: pubmed publisher |
Nahmad A, Raviv Y, Horovitz Fried M, Sofer I, Akriv T, Nataf D, et al. Engineered B cells expressing an anti-HIV antibody enable memory retention, isotype switching and clonal expansion. Nat Commun. 2020;11:5851 pubmed publisher |
Giuli M, Diluvio G, Giuliani E, Franciosa G, Di Magno L, Pignataro M, et al. Notch3 contributes to T-cell leukemia growth via regulation of the unfolded protein response. Oncogenesis. 2020;9:93 pubmed publisher |
Kurup S, Moioffer S, Pewe L, Harty J. p53 Hinders CRISPR/Cas9-Mediated Targeted Gene Disruption in Memory CD8 T Cells In Vivo. J Immunol. 2020;205:2222-2230 pubmed publisher |
Linder A, Bauernfried S, Cheng Y, Albanese M, Jung C, Keppler O, et al. CARD8 inflammasome activation triggers pyroptosis in human T cells. EMBO J. 2020;39:e105071 pubmed publisher |
Shin D, Huang X, Gil C, Aljoufi A, Ropa J, Broxmeyer H. Physioxia enhances T-cell development ex vivo from human hematopoietic stem and progenitor cells. Stem Cells. 2020;38:1454-1466 pubmed publisher |
Li Z, Zhang H, Huang Y, Huang J, Sun P, Zhou N, et al. Autophagy deficiency promotes triple-negative breast cancer resistance to T cell-mediated cytotoxicity by blocking tenascin-C degradation. Nat Commun. 2020;11:3806 pubmed publisher |
Wang T, Medynets M, Johnson K, Doucet O Hare T, DiSanza B, Li W, et al. Regulation of stem cell function and neuronal differentiation by HERV-K via mTOR pathway. Proc Natl Acad Sci U S A. 2020;117:17842-17853 pubmed publisher |
Rust B, Kean L, Colonna L, Brandenstein K, Poole N, Obenza W, et al. Robust expansion of HIV CAR T cells following antigen boosting in ART-suppressed nonhuman primates. Blood. 2020;136:1722-1734 pubmed publisher |
Le J, Park J, Ha V, Luong A, Branciamore S, Rodin A, et al. Single-Cell RNA-Seq Mapping of Human Thymopoiesis Reveals Lineage Specification Trajectories and a Commitment Spectrum in T Cell Development. Immunity. 2020;52:1105-1118.e9 pubmed publisher |
Meyer L, Verbist K, Albeituni S, Scull B, Bassett R, Stroh A, et al. JAK/STAT pathway inhibition sensitizes CD8 T cells to dexamethasone-induced apoptosis in hyperinflammation. Blood. 2020;136:657-668 pubmed publisher |
Meng K, Majedi F, Thauland T, Butte M. Mechanosensing through YAP controls T cell activation and metabolism. J Exp Med. 2020;217: pubmed publisher |
Cao W, Fang F, Gould T, Li X, Kim C, Gustafson C, et al. Ecto-NTPDase CD39 is a negative checkpoint that inhibits follicular helper cell generation. J Clin Invest. 2020;130:3422-3436 pubmed publisher |
Liu G, Deng X, Li X, Cao Y, Xing Y, Zhou P, et al. Expansion of Group 2 Innate Lymphoid Cells in Patients with End-Stage Renal Disease and Their Clinical Significance. J Immunol. 2020;205:36-44 pubmed publisher |
Gaydosik A, Queen D, Trager M, Akilov O, Geskin L, Fuschiotti P. Genome-wide transcriptome analysis of the STAT6-regulated genes in advanced-stage cutaneous T-cell lymphoma. Blood. 2020;136:1748-1759 pubmed publisher |
Côté S, Burke Schinkel S, Berthoud T, Barros P, Sanchez Vidales M, Davidson A, et al. IL-7 induces sCD127 release and mCD127 downregulation in human CD8+ T cells by distinct yet overlapping mechanisms, both of which are impaired in HIV infection. Eur J Immunol. 2020;50:1537-1549 pubmed publisher |
De Smedt R, Morscio J, Reunes L, Roels J, Bardelli V, Lintermans B, et al. Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma. Blood. 2020;135:1685-1695 pubmed publisher |
Han K, Park D, Ju S, Lee Y, Heo S, Kim Y, et al. Streamlined selection of cancer antigens for vaccine development through integrative multi-omics and high-content cell imaging. Sci Rep. 2020;10:5885 pubmed publisher |
Ruscetti M, Morris J, Mezzadra R, Russell J, Leibold J, Romesser P, et al. Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer. Cell. 2020;181:424-441.e21 pubmed publisher |
Lichtenegger F, Schnorfeil F, Rothe M, Deiser K, Altmann T, B xfc cklein V, et al. Toll-like receptor 7/8-matured RNA-transduced dendritic cells as post-remission therapy in acute myeloid leukaemia: results of a phase I trial. Clin Transl Immunology. 2020;9:e1117 pubmed publisher |
Kared H, Tan S, Lau M, Chevrier M, Tan C, How W, et al. Immunological history governs human stem cell memory CD4 heterogeneity via the Wnt signaling pathway. Nat Commun. 2020;11:821 pubmed publisher |
Sun C, Shou P, Du H, Hirabayashi K, Chen Y, Herring L, et al. THEMIS-SHP1 Recruitment by 4-1BB Tunes LCK-Mediated Priming of Chimeric Antigen Receptor-Redirected T Cells. Cancer Cell. 2020;37:216-225.e6 pubmed publisher |
Huang B, Luo L, Wang J, He B, Feng R, Xian N, et al. B7-H3 specific T cells with chimeric antigen receptor and decoy PD-1 receptors eradicate established solid human tumors in mouse models. Oncoimmunology. 2020;9:1684127 pubmed publisher |
Themeli M, Chhatta A, Boersma H, Prins H, Cordes M, de Wilt E, et al. iPSC-Based Modeling of RAG2 Severe Combined Immunodeficiency Reveals Multiple T Cell Developmental Arrests. Stem Cell Reports. 2020;14:300-311 pubmed publisher |
Elmetwali T, Salman A, Wei W, Hussain S, Young L, Palmer D. CD40L membrane retention enhances the immunostimulatory effects of CD40 ligation. Sci Rep. 2020;10:342 pubmed publisher |
Souter M, Loh L, Li S, Meehan B, Gherardin N, Godfrey D, et al. Characterization of Human Mucosal-associated Invariant T (MAIT) Cells. Curr Protoc Immunol. 2019;127:e90 pubmed publisher |
Anderson W, Thorpe J, Long S, Rawlings D. Efficient CRISPR/Cas9 Disruption of Autoimmune-Associated Genes Reveals Key Signaling Programs in Primary Human T Cells. J Immunol. 2019;203:3166-3178 pubmed publisher |
Meyer L, Huang B, Delgado Martín C, Roy R, Hechmer A, Wandler A, et al. Glucocorticoids paradoxically facilitate steroid resistance in T cell acute lymphoblastic leukemias and thymocytes. J Clin Invest. 2020;130:863-876 pubmed publisher |
Zhou W, Yui M, Williams B, Yun J, Wold B, Cai L, et al. Single-Cell Analysis Reveals Regulatory Gene Expression Dynamics Leading to Lineage Commitment in Early T Cell Development. Cell Syst. 2019;9:321-337.e9 pubmed publisher |
Zeng Y, Liu C, Gong Y, Bai Z, Hou S, He J, et al. Single-Cell RNA Sequencing Resolves Spatiotemporal Development of Pre-thymic Lymphoid Progenitors and Thymus Organogenesis in Human Embryos. Immunity. 2019;51:930-948.e6 pubmed publisher |
Al Mossawi H, Yager N, Taylor C, Lau E, Danielli S, de Wit J, et al. Context-specific regulation of surface and soluble IL7R expression by an autoimmune risk allele. Nat Commun. 2019;10:4575 pubmed publisher |
Yazdanifar M, Zhou R, Grover P, Williams C, Bose M, Moore L, et al. Overcoming Immunological Resistance Enhances the Efficacy of A Novel Anti-tMUC1-CAR T Cell Treatment against Pancreatic Ductal Adenocarcinoma. Cells. 2019;8: pubmed publisher |
Zhu Y, Smith D, Zhou Y, Li Y, Yu J, Lee D, et al. Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer. Cell Stem Cell. 2019;25:542-557.e9 pubmed publisher |
Figueiredo C, Eicke D, Yuzefovych Y, Avsar M, Hanke J, Pflaum M, et al. Low immunogenic endothelial cells endothelialize the Left Ventricular Assist Device. Sci Rep. 2019;9:11318 pubmed publisher |
Kusakabe M, Sun A, Tyshchenko K, Wong R, Nanda A, Shanna C, et al. Synthetic modeling reveals HOXB genes are critical for the initiation and maintenance of human leukemia. Nat Commun. 2019;10:2913 pubmed publisher |
Cella M, Gamini R, Sécca C, Collins P, Zhao S, Peng V, et al. Subsets of ILC3-ILC1-like cells generate a diversity spectrum of innate lymphoid cells in human mucosal tissues. Nat Immunol. 2019;: pubmed publisher |
Zhang G, Luk B, Wei X, Campbell G, Fang R, Zhang L, et al. Selective cell death of latently HIV-infected CD4+ T cells mediated by autosis inducing nanopeptides. Cell Death Dis. 2019;10:419 pubmed publisher |
Fan J, Liang H, Ji X, Wang S, Xue J, Li D, et al. CTL-mediated immunotherapy can suppress SHIV rebound in ART-free macaques. Nat Commun. 2019;10:2257 pubmed publisher |
Seol M, Kim J, Oh K, Kim G, Seo M, Shin Y, et al. Interleukin-7 Contributes to the Invasiveness of Prostate Cancer Cells by Promoting Epithelial-Mesenchymal Transition. Sci Rep. 2019;9:6917 pubmed publisher |
Martinez Usatorre A, Sempere L, Carmona S, Carretero Iglesia L, Monnot G, Speiser D, et al. MicroRNA-155 Expression Is Enhanced by T-cell Receptor Stimulation Strength and Correlates with Improved Tumor Control in Melanoma. Cancer Immunol Res. 2019;7:1013-1024 pubmed publisher |
Zhang Z, Gothe F, Pennamen P, James J, McDonald D, Mata C, et al. Human interleukin-2 receptor β mutations associated with defects in immunity and peripheral tolerance. J Exp Med. 2019;216:1311-1327 pubmed publisher |
Fernandez I, Baxter R, Garcia Perez J, Vendrame E, Ranganath T, Kong D, et al. A novel human IL2RB mutation results in T and NK cell-driven immune dysregulation. J Exp Med. 2019;216:1255-1267 pubmed publisher |
Mesquitta W, Wandsnider M, Kang H, Thomson J, Moskvin O, Suknuntha K, et al. UM171 expands distinct types of myeloid and NK progenitors from human pluripotent stem cells. Sci Rep. 2019;9:6622 pubmed publisher |
Luong Gardiol N, Siddiqui I, Pizzitola I, Jeevan Raj B, Charmoy M, Huang Y, et al. γ-Catenin-Dependent Signals Maintain BCR-ABL1+ B Cell Acute Lymphoblastic Leukemia. Cancer Cell. 2019;35:649-663.e10 pubmed publisher |
Pavel Dinu M, Wiebking V, Dejene B, Srifa W, Mantri S, Nicolas C, et al. Gene correction for SCID-X1 in long-term hematopoietic stem cells. Nat Commun. 2019;10:1634 pubmed publisher |
Akkapeddi P, Fragoso R, Hixon J, Ramalho A, Oliveira M, Carvalho T, et al. A fully human anti-IL-7Rα antibody promotes antitumor activity against T-cell acute lymphoblastic leukemia. Leukemia. 2019;: pubmed publisher |
Du H, Hirabayashi K, Ahn S, Kren N, Montgomery S, Wang X, et al. Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells. Cancer Cell. 2019;35:221-237.e8 pubmed publisher |
Parks C, Henning K, Pavelko K, Hansen M, Van Keulen V, Reed B, et al. Breaking tolerance with engineered class I antigen-presenting molecules. Proc Natl Acad Sci U S A. 2019;116:3136-3145 pubmed publisher |
Weijenborg Campos L, Pini Zenatti P, Granato Pissinato L, Libanio Rodrigues G, Artico L, Rafael Guimar xe3 es T, et al. Oncogenic basic amino acid insertions at the extracellular juxtamembrane region of IL7RA cause receptor hypersensitivity. Blood. 2019;133:1259-1263 pubmed publisher |
Lopez Millan B, Sanchez Martínez D, Roca Ho H, Gutiérrez Agüera F, Molina O, Díaz de la Guardia R, et al. NG2 antigen is a therapeutic target for MLL-rearranged B-cell acute lymphoblastic leukemia. Leukemia. 2019;: pubmed publisher |
Nayak R, Hegde S, Althoff M, Wellendorf A, Mohmoud F, Perentesis J, et al. The signaling axis atypical protein kinase C λ/ι-Satb2 mediates leukemic transformation of B-cell progenitors. Nat Commun. 2019;10:46 pubmed publisher |
Meng X, Liu X, Guo X, Jiang S, Chen T, Hu Z, et al. FBXO38 mediates PD-1 ubiquitination and regulates anti-tumour immunity of T cells. Nature. 2018;564:130-135 pubmed publisher |
Vrecko S, Guenat D, Mercier Letondal P, Faucheu H, Dosset M, Royer B, et al. Personalized identification of tumor-associated immunogenic neoepitopes in hepatocellular carcinoma in complete remission after sorafenib treatment. Oncotarget. 2018;9:35394-35407 pubmed publisher |
Vasko T, Hoffmann J, Gostek S, Schettgen T, Quinete N, Preisinger C, et al. Telomerase gene expression bioassays indicate metabolic activation of genotoxic lower chlorinated polychlorinated biphenyls. Sci Rep. 2018;8:16903 pubmed publisher |
Campbell G, Bruckman R, Chu Y, Trout R, Spector S. SMAC Mimetics Induce Autophagy-Dependent Apoptosis of HIV-1-Infected Resting Memory CD4+ T Cells. Cell Host Microbe. 2018;24:689-702.e7 pubmed publisher |
Giambra V, Gusscott S, Gracias D, Song R, Lam S, Panelli P, et al. Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity. Cell Stem Cell. 2018;23:714-726.e7 pubmed publisher |
Mudd J, Busman Sahay K, DiNapoli S, Lai S, Sheik V, Lisco A, et al. Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells. Nat Commun. 2018;9:3967 pubmed publisher |
Kauts M, De Leo B, Rodríguez Seoane C, Ronn R, Glykofrydis F, Maglitto A, et al. Rapid Mast Cell Generation from Gata2 Reporter Pluripotent Stem Cells. Stem Cell Reports. 2018;11:1009-1020 pubmed publisher |
Laustsen A, Bak R, Krapp C, Kjær L, Egedahl J, Petersen C, et al. Interferon priming is essential for human CD34+ cell-derived plasmacytoid dendritic cell maturation and function. Nat Commun. 2018;9:3525 pubmed publisher |
Ngai H, Tian G, Courtney A, Ravari S, Guo L, Liu B, et al. IL-21 Selectively Protects CD62L+ NKT Cells and Enhances Their Effector Functions for Adoptive Immunotherapy. J Immunol. 2018;201:2141-2153 pubmed publisher |
Balan S, Arnold Schrauf C, Abbas A, Couespel N, Savoret J, Imperatore F, et al. Large-Scale Human Dendritic Cell Differentiation Revealing Notch-Dependent Lineage Bifurcation and Heterogeneity. Cell Rep. 2018;24:1902-1915.e6 pubmed publisher |
Aue G, Sun C, Liu D, Park J, Pittaluga S, Tian X, et al. Activation of Th1 Immunity within the Tumor Microenvironment Is Associated with Clinical Response to Lenalidomide in Chronic Lymphocytic Leukemia. J Immunol. 2018;201:1967-1974 pubmed publisher |
Lee J, Jeong E, Lee J, Jung M, Shin E, Kim Y, et al. Directed evolution of CRISPR-Cas9 to increase its specificity. Nat Commun. 2018;9:3048 pubmed publisher |
Helsen C, Hammill J, Lau V, Mwawasi K, Afsahi A, Bezverbnaya K, et al. The chimeric TAC receptor co-opts the T cell receptor yielding robust anti-tumor activity without toxicity. Nat Commun. 2018;9:3049 pubmed publisher |
Badia R, Ballana E, Castellví M, Garcia Vidal E, Pujantell M, Clotet B, et al. CD32 expression is associated to T-cell activation and is not a marker of the HIV-1 reservoir. Nat Commun. 2018;9:2739 pubmed publisher |
Hosokawa H, Ungerbäck J, Wang X, Matsumoto M, Nakayama K, Cohen S, et al. Transcription Factor PU.1 Represses and Activates Gene Expression in Early T Cells by Redirecting Partner Transcription Factor Binding. Immunity. 2018;48:1119-1134.e7 pubmed publisher |
Bando J, Gilfillan S, Song C, McDonald K, Huang S, Newberry R, et al. The Tumor Necrosis Factor Superfamily Member RANKL Suppresses Effector Cytokine Production in Group 3 Innate Lymphoid Cells. Immunity. 2018;48:1208-1219.e4 pubmed publisher |
Ueda N, Uemura Y, Zhang R, Kitayama S, Iriguchi S, Kawai Y, et al. Generation of TCR-Expressing Innate Lymphoid-like Helper Cells that Induce Cytotoxic T Cell-Mediated Anti-leukemic Cell Response. Stem Cell Reports. 2018;: pubmed publisher |
Maclean G, McEldoon J, Huang J, Allred J, Canver M, Orkin S. Downregulation of Endothelin Receptor B Contributes to Defective B Cell Lymphopoiesis in Trisomy 21 Pluripotent Stem Cells. Sci Rep. 2018;8:8001 pubmed publisher |
Uenishi G, Jung H, Kumar A, Park M, Hadland B, McLeod E, et al. NOTCH signaling specifies arterial-type definitive hemogenic endothelium from human pluripotent stem cells. Nat Commun. 2018;9:1828 pubmed publisher |
Lichtenegger F, Rothe M, Schnorfeil F, Deiser K, Krupka C, Augsberger C, et al. Targeting LAG-3 and PD-1 to Enhance T Cell Activation by Antigen-Presenting Cells. Front Immunol. 2018;9:385 pubmed publisher |
Li N, van Unen V, Höllt T, Thompson A, van Bergen J, Pezzotti N, et al. Mass cytometry reveals innate lymphoid cell differentiation pathways in the human fetal intestine. J Exp Med. 2018;215:1383-1396 pubmed publisher |
Booth C, Barkas N, Neo W, Boukarabila H, Soilleux E, Giotopoulos G, et al. Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors. Cancer Cell. 2018;33:274-291.e8 pubmed publisher |
Kim J, Chang D, Lee H, Lee H, Kim J, Sung P, et al. Innate-like Cytotoxic Function of Bystander-Activated CD8+ T Cells Is Associated with Liver Injury in Acute Hepatitis A. Immunity. 2018;48:161-173.e5 pubmed publisher |
Jiang Z, Wu D, Ye W, Weng J, Lai P, Shi P, et al. Defined, serum/feeder-free conditions for expansion and drug screening of primary B-acute lymphoblastic leukemia. Oncotarget. 2017;8:106382-106392 pubmed publisher |
Böiers C, Richardson S, Laycock E, Zriwil A, Turati V, Brown J, et al. A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1. Dev Cell. 2018;44:362-377.e7 pubmed publisher |
Akondy R, Fitch M, Edupuganti S, Yang S, Kissick H, Li K, et al. Origin and differentiation of human memory CD8 T cells after vaccination. Nature. 2017;: pubmed publisher |
Zeng J, Tang S, Toh L, Wang S. Generation of "Off-the-Shelf" Natural Killer Cells from Peripheral Blood Cell-Derived Induced Pluripotent Stem Cells. Stem Cell Reports. 2017;9:1796-1812 pubmed publisher |
Al Mossawi M, Chen L, Fang H, Ridley A, de Wit J, Yager N, et al. Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis. Nat Commun. 2017;8:1510 pubmed publisher |
Robles Valero J, Lorenzo Martín L, Menacho Márquez M, Fernández Pisonero I, Abad A, Camos M, et al. A Paradoxical Tumor-Suppressor Role for the Rac1 Exchange Factor Vav1 in T Cell Acute Lymphoblastic Leukemia. Cancer Cell. 2017;32:608-623.e9 pubmed publisher |
Ripamonti A, Provasi E, Lorenzo M, De Simone M, Ranzani V, Vangelisti S, et al. Repression of miR-31 by BCL6 stabilizes the helper function of human follicular helper T cells. Proc Natl Acad Sci U S A. 2017;114:12797-12802 pubmed publisher |
Sabins N, Chornoguz O, Leander K, Kaplan F, Carter R, Kinder M, et al. TIM-3 Engagement Promotes Effector Memory T Cell Differentiation of Human Antigen-Specific CD8 T Cells by Activating mTORC1. J Immunol. 2017;199:4091-4102 pubmed publisher |
Nastasi C, Fredholm S, Willerslev Olsen A, Hansen M, Bonefeld C, Geisler C, et al. Butyrate and propionate inhibit antigen-specific CD8+ T cell activation by suppressing IL-12 production by antigen-presenting cells. Sci Rep. 2017;7:14516 pubmed publisher |
Serafin V, Capuzzo G, Milani G, Minuzzo S, Pinazza M, Bortolozzi R, et al. Glucocorticoid resistance is reverted by LCK inhibition in pediatric T-cell acute lymphoblastic leukemia. Blood. 2017;: pubmed publisher |
Park S, Shevlin E, Vedvyas Y, Zaman M, Park S, Hsu Y, et al. Micromolar affinity CAR T cells to ICAM-1 achieves rapid tumor elimination while avoiding systemic toxicity. Sci Rep. 2017;7:14366 pubmed publisher |
Clénet M, Gagnon F, Moratalla A, Viel E, Arbour N. Peripheral human CD4+CD8+ T lymphocytes exhibit a memory phenotype and enhanced responses to IL-2, IL-7 and IL-15. Sci Rep. 2017;7:11612 pubmed publisher |
Ucar D, Márquez E, Chung C, Marches R, Rossi R, Uyar A, et al. The chromatin accessibility signature of human immune aging stems from CD8+ T cells. J Exp Med. 2017;214:3123-3144 pubmed publisher |
Minami H, Nagaharu K, Nakamori Y, Ohishi K, Shimojo N, Kageyama Y, et al. CXCL12-CXCR4 Axis Is Required for Contact-Mediated Human B Lymphoid and Plasmacytoid Dendritic Cell Differentiation but Not T Lymphoid Generation. J Immunol. 2017;199:2343-2355 pubmed publisher |
Li Y, Brauer P, Singh J, Xhiku S, Yoganathan K, Zuniga Pflucker J, et al. Targeted Disruption of TCF12 Reveals HEB as Essential in Human Mesodermal Specification and Hematopoiesis. Stem Cell Reports. 2017;9:779-795 pubmed publisher |
Das A, Rouault Pierre K, Kamdar S, Gomez Tourino I, Wood K, Donaldson I, et al. Adaptive from Innate: Human IFN-γ+CD4+ T Cells Can Arise Directly from CXCL8-Producing Recent Thymic Emigrants in Babies and Adults. J Immunol. 2017;199:1696-1705 pubmed publisher |
Zanon V, Pilipow K, Scamardella E, De Paoli F, De Simone G, Price D, et al. Curtailed T-cell activation curbs effector differentiation and generates CD8+ T cells with a naturally-occurring memory stem cell phenotype. Eur J Immunol. 2017;47:1468-1476 pubmed publisher |
Schmueck Henneresse M, Omer B, Shum T, Tashiro H, Mamonkin M, Lapteva N, et al. Comprehensive Approach for Identifying the T Cell Subset Origin of CD3 and CD28 Antibody-Activated Chimeric Antigen Receptor-Modified T Cells. J Immunol. 2017;199:348-362 pubmed publisher |
Delgado Martín C, Meyer L, Huang B, Shimano K, Zinter M, Nguyen J, et al. JAK/STAT pathway inhibition overcomes IL7-induced glucocorticoid resistance in a subset of human T-cell acute lymphoblastic leukemias. Leukemia. 2017;31:2568-2576 pubmed publisher |
Belderbos M, Koster T, Ausema B, Jacobs S, Sowdagar S, Zwart E, et al. Clonal selection and asymmetric distribution of human leukemia in murine xenografts revealed by cellular barcoding. Blood. 2017;129:3210-3220 pubmed publisher |
Kotini A, Chang C, Chow A, Yuan H, Ho T, Wang T, et al. Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia. Cell Stem Cell. 2017;20:315-328.e7 pubmed publisher |
Abolhassani H, Edwards E, Ikinciogullari A, Jing H, Borte S, Buggert M, et al. Combined immunodeficiency and Epstein-Barr virus-induced B cell malignancy in humans with inherited CD70 deficiency. J Exp Med. 2017;214:91-106 pubmed publisher |
Bassani Sternberg M, Bräunlein E, Klar R, Engleitner T, Sinitcyn P, Audehm S, et al. Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry. Nat Commun. 2016;7:13404 pubmed publisher |
Cuff A, Robertson F, Stegmann K, Pallett L, Maini M, Davidson B, et al. Eomeshi NK Cells in Human Liver Are Long-Lived and Do Not Recirculate but Can Be Replenished from the Circulation. J Immunol. 2016;197:4283-4291 pubmed |
Gregory M, D Alessandro A, Alvarez Calderon F, Kim J, Nemkov T, Adane B, et al. ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia. Proc Natl Acad Sci U S A. 2016;113:E6669-E6678 pubmed |
Romano Ibarra G, Paul B, Sather B, Younan P, Sommer K, Kowalski J, et al. Efficient Modification of the CCR5 Locus in Primary Human T Cells With megaTAL Nuclease Establishes HIV-1 Resistance. Mol Ther Nucleic Acids. 2016;5:e352 pubmed publisher |
Amabile A, Migliara A, Capasso P, Biffi M, Cittaro D, Naldini L, et al. Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing. Cell. 2016;167:219-232.e14 pubmed publisher |
Lykken E, Li Q. The MicroRNA miR-191 Supports T Cell Survival Following Common ? Chain Signaling. J Biol Chem. 2016;291:23532-23544 pubmed |
Kagoya Y, Nakatsugawa M, Yamashita Y, Ochi T, Guo T, Anczurowski M, et al. BET bromodomain inhibition enhances T cell persistence and function in adoptive immunotherapy models. J Clin Invest. 2016;126:3479-94 pubmed publisher |
Galaine J, Kellermann G, Guillaume Y, Boidot R, Picard E, Loyon R, et al. Heparan Sulfate Proteoglycans Promote Telomerase Internalization and MHC Class II Presentation on Dendritic Cells. J Immunol. 2016;197:1597-608 pubmed publisher |
Woytschak J, Keller N, Krieg C, Impellizzieri D, Thompson R, Wynn T, et al. Type 2 Interleukin-4 Receptor Signaling in Neutrophils Antagonizes Their Expansion and Migration during Infection and Inflammation. Immunity. 2016;45:172-84 pubmed publisher |
Dan J, Lindestam Arlehamn C, Weiskopf D, da Silva Antunes R, Havenar Daughton C, Reiss S, et al. A Cytokine-Independent Approach To Identify Antigen-Specific Human Germinal Center T Follicular Helper Cells and Rare Antigen-Specific CD4+ T Cells in Blood. J Immunol. 2016;197:983-93 pubmed publisher |
Gomez Cadena A, Urueña C, Prieto K, Martinez Usatorre A, Donda A, Barreto A, et al. Immune-system-dependent anti-tumor activity of a plant-derived polyphenol rich fraction in a melanoma mouse model. Cell Death Dis. 2016;7:e2243 pubmed publisher |
Grier A, Burleigh S, Sahni J, Clough C, Cardot V, Choe D, et al. pEVL: A Linear Plasmid for Generating mRNA IVT Templates With Extended Encoded Poly(A) Sequences. Mol Ther Nucleic Acids. 2016;5:e306 pubmed publisher |
Korfi K, Smith M, Swan J, Somervaille T, Dhomen N, Marais R. BIM mediates synergistic killing of B-cell acute lymphoblastic leukemia cells by BCL-2 and MEK inhibitors. Cell Death Dis. 2016;7:e2177 pubmed publisher |
Serr I, Fürst R, Achenbach P, Scherm M, Gökmen F, Haupt F, et al. Type 1 diabetes vaccine candidates promote human Foxp3(+)Treg induction in humanized mice. Nat Commun. 2016;7:10991 pubmed publisher |
D Souza S, Maufort J, Kumar A, Zhang J, Smuga Otto K, Thomson J, et al. GSK3β Inhibition Promotes Efficient Myeloid and Lymphoid Hematopoiesis from Non-human Primate-Induced Pluripotent Stem Cells. Stem Cell Reports. 2016;6:243-56 pubmed publisher |
Yin J, Leavenworth J, Li Y, Luo Q, Xie H, Liu X, et al. Ezh2 regulates differentiation and function of natural killer cells through histone methyltransferase activity. Proc Natl Acad Sci U S A. 2015;112:15988-93 pubmed publisher |
Bending D, Giannakopoulou E, Lom H, Wedderburn L. Synovial Regulatory T Cells Occupy a Discrete TCR Niche in Human Arthritis and Require Local Signals To Stabilize FOXP3 Protein Expression. J Immunol. 2015;195:5616-24 pubmed publisher |
Chen Q, Ye W, Jian Tan W, Mei Yong K, Liu M, Qi Tan S, et al. Delineation of Natural Killer Cell Differentiation from Myeloid Progenitors in Human. Sci Rep. 2015;5:15118 pubmed publisher |
Leone P, Berardi S, Frassanito M, Ria R, De Re V, Cicco S, et al. Dendritic cells accumulate in the bone marrow of myeloma patients where they protect tumor plasma cells from CD8+ T-cell killing. Blood. 2015;126:1443-51 pubmed publisher |
Allam A, Majji S, Peachman K, Jagodzinski L, Kim J, Ratto Kim S, et al. TFH cells accumulate in mucosal tissues of humanized-DRAG mice and are highly permissive to HIV-1. Sci Rep. 2015;5:10443 pubmed publisher |
Wegner J, Hackenberg S, Scholz C, Chuvpilo S, Tyrsin D, Matskevich A, et al. High-density preculture of PBMCs restores defective sensitivity of circulating CD8 T cells to virus- and tumor-derived antigens. Blood. 2015;126:185-94 pubmed publisher |
van der Geest K, Abdulahad W, Teteloshvili N, Tete S, Peters J, Horst G, et al. Low-affinity TCR engagement drives IL-2-dependent post-thymic maintenance of naive CD4+ T cells in aged humans. Aging Cell. 2015;14:744-53 pubmed publisher |
Vamos C, Calvo A, Daley E, Giuliano A, López Castillo H. Knowledge, Behavioral, and Sociocultural Factors Related to Human Papillomavirus Infection and Cervical Cancer Screening Among Inner-City Women in Panama. J Community Health. 2015;40:1047-56 pubmed publisher |
Nagai Y, Kawahara M, Hishizawa M, Shimazu Y, Sugino N, Fujii S, et al. T memory stem cells are the hierarchical apex of adult T-cell leukemia. Blood. 2015;125:3527-35 pubmed publisher |
McClellan J, Dove C, Gentles A, Ryan C, Majeti R. Reprogramming of primary human Philadelphia chromosome-positive B cell acute lymphoblastic leukemia cells into nonleukemic macrophages. Proc Natl Acad Sci U S A. 2015;112:4074-9 pubmed publisher |
Geskin L, Viragova S, Stolz D, Fuschiotti P. Interleukin-13 is overexpressed in cutaneous T-cell lymphoma cells and regulates their proliferation. Blood. 2015;125:2798-805 pubmed publisher |
Mayanagi S, Kitago M, Sakurai T, Matsuda T, Fujita T, Higuchi H, et al. Phase I pilot study of Wilms tumor gene 1 peptide-pulsed dendritic cell vaccination combined with gemcitabine in pancreatic cancer. Cancer Sci. 2015;106:397-406 pubmed publisher |
Ferrell P, Xi J, Ma C, Adlakha M, Kaufman D. The RUNX1 +24 enhancer and P1 promoter identify a unique subpopulation of hematopoietic progenitor cells derived from human pluripotent stem cells. Stem Cells. 2015;33:1130-41 pubmed publisher |
Salio M, Puleston D, Mathan T, Shepherd D, Stranks A, Adamopoulou E, et al. Essential role for autophagy during invariant NKT cell development. Proc Natl Acad Sci U S A. 2014;111:E5678-87 pubmed publisher |
Arber C, Feng X, Abhyankar H, Romero E, Wu M, Heslop H, et al. Survivin-specific T cell receptor targets tumor but not T cells. J Clin Invest. 2015;125:157-68 pubmed publisher |
Laffont S, Rouquié N, Azar P, Seillet C, Plumas J, Aspord C, et al. X-Chromosome complement and estrogen receptor signaling independently contribute to the enhanced TLR7-mediated IFN-α production of plasmacytoid dendritic cells from women. J Immunol. 2014;193:5444-52 pubmed publisher |
Reid R, Redman J, Rizkallah P, Fegan C, Pepper C, Man S. CD8+ T-cell recognition of a synthetic epitope formed by t-butyl modification. Immunology. 2014;: pubmed publisher |
Pan Q, Pan K, Wang Q, Weng D, Zhao J, Zheng H, et al. Annexin A3 as a potential target for immunotherapy of liver cancer stem-like cells. Stem Cells. 2015;33:354-66 pubmed publisher |
Stephen T, Rutkowski M, Allegrezza M, Perales Puchalt A, Tesone A, Svoronos N, et al. Transforming growth factor β-mediated suppression of antitumor T cells requires FoxP1 transcription factor expression. Immunity. 2014;41:427-439 pubmed publisher |
Nazzal D, Gradolatto A, Truffault F, Bismuth J, Berrih Aknin S. Human thymus medullary epithelial cells promote regulatory T-cell generation by stimulating interleukin-2 production via ICOS ligand. Cell Death Dis. 2014;5:e1420 pubmed publisher |
Qi Q, Liu Y, Cheng Y, Glanville J, Zhang D, Lee J, et al. Diversity and clonal selection in the human T-cell repertoire. Proc Natl Acad Sci U S A. 2014;111:13139-44 pubmed publisher |
Zhao L, Mei Y, Sun Q, Guo L, Wu Y, Yu X, et al. Autologous tumor vaccine modified with recombinant new castle disease virus expressing IL-7 promotes antitumor immune response. J Immunol. 2014;193:735-45 pubmed publisher |
Zhang S, Wang X, Manna S, Zlotoff D, Bryson J, Blazar B, et al. Chemokine treatment rescues profound T-lineage progenitor homing defect after bone marrow transplant conditioning in mice. Blood. 2014;124:296-304 pubmed publisher |
Genovese P, Schiroli G, Escobar G, Tomaso T, Firrito C, Calabria A, et al. Targeted genome editing in human repopulating haematopoietic stem cells. Nature. 2014;510:235-240 pubmed publisher |
Miller M, Mashayekhi M, Chen L, Zhou P, Liu X, Michelotti M, et al. Basal NF-?B controls IL-7 responsiveness of quiescent naïve T cells. Proc Natl Acad Sci U S A. 2014;111:7397-402 pubmed publisher |
Xu Y, Zhang M, Ramos C, Durett A, Liu E, Dakhova O, et al. Closely related T-memory stem cells correlate with in vivo expansion of CAR.CD19-T cells and are preserved by IL-7 and IL-15. Blood. 2014;123:3750-9 pubmed publisher |
Nair S, Tomaras G, Sales A, Boczkowski D, Chan C, Plonk K, et al. High-throughput identification and dendritic cell-based functional validation of MHC class I-restricted Mycobacterium tuberculosis epitopes. Sci Rep. 2014;4:4632 pubmed publisher |
Gang A, Frøsig T, Brimnes M, Lyngaa R, Treppendahl M, Grønbæk K, et al. 5-Azacytidine treatment sensitizes tumor cells to T-cell mediated cytotoxicity and modulates NK cells in patients with myeloid malignancies. Blood Cancer J. 2014;4:e197 pubmed publisher |
Morandi F, Di Carlo E, Ferrone S, Petretto A, Pistoia V, Airoldi I. IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation. J Immunol. 2014;192:2634-42 pubmed publisher |
Kim P, Jochems C, Grenga I, Donahue R, Tsang K, Gulley J, et al. Pan-Bcl-2 inhibitor, GX15-070 (obatoclax), decreases human T regulatory lymphocytes while preserving effector T lymphocytes: a rationale for its use in combination immunotherapy. J Immunol. 2014;192:2622-33 pubmed publisher |
Du M, Guo P, Piao H, Wang S, Sun C, Jin L, et al. Embryonic trophoblasts induce decidual regulatory T cell differentiation and maternal-fetal tolerance through thymic stromal lymphopoietin instructing dendritic cells. J Immunol. 2014;192:1502-11 pubmed publisher |
Bonami R, Sullivan A, Case J, Steinberg H, Hoek K, Khan W, et al. Bruton's tyrosine kinase promotes persistence of mature anti-insulin B cells. J Immunol. 2014;192:1459-70 pubmed publisher |
Volonté A, Di Tomaso T, Spinelli M, Todaro M, Sanvito F, Albarello L, et al. Cancer-initiating cells from colorectal cancer patients escape from T cell-mediated immunosurveillance in vitro through membrane-bound IL-4. J Immunol. 2014;192:523-32 pubmed publisher |
Casucci M, Nicolis Di Robilant B, Falcone L, Camisa B, Norelli M, Genovese P, et al. CD44v6-targeted T cells mediate potent antitumor effects against acute myeloid leukemia and multiple myeloma. Blood. 2013;122:3461-72 pubmed publisher |
Li L, Nishio J, van Maurik A, Mathis D, Benoist C. Differential response of regulatory and conventional CD4? lymphocytes to CD3 engagement: clues to a possible mechanism of anti-CD3 action?. J Immunol. 2013;191:3694-704 pubmed publisher |
Fernandez I, Ooi T, Roy K. Generation of functional, antigen-specific CD8+ human T cells from cord blood stem cells using exogenous Notch and tetramer-TCR signaling. Stem Cells. 2014;32:93-104 pubmed publisher |
Koss B, Morrison J, Perciavalle R, Singh H, Rehg J, Williams R, et al. Requirement for antiapoptotic MCL-1 in the survival of BCR-ABL B-lineage acute lymphoblastic leukemia. Blood. 2013;122:1587-98 pubmed publisher |
Wolfl M, Schwinn S, Yoo Y, Reß M, Braun M, Chopra M, et al. Src-kinase inhibitors sensitize human cells of myeloid origin to Toll-like-receptor-induced interleukin 12 synthesis. Blood. 2013;122:1203-13 pubmed publisher |
Henry Bonami R, Williams J, Rachakonda A, Karamali M, Kendall P, Thomas J. B lymphocyte "original sin" in the bone marrow enhances islet autoreactivity in type 1 diabetes-prone nonobese diabetic mice. J Immunol. 2013;190:5992-6003 pubmed publisher |
Kyoizumi S, Kubo Y, Kajimura J, Yoshida K, Imai K, Hayashi T, et al. Age-associated changes in the differentiation potentials of human circulating hematopoietic progenitors to T- or NK-lineage cells. J Immunol. 2013;190:6164-72 pubmed publisher |
Miyazaki Y, Fujiwara H, Asai H, Ochi F, Ochi T, Azuma T, et al. Development of a novel redirected T-cell-based adoptive immunotherapy targeting human telomerase reverse transcriptase for adult T-cell leukemia. Blood. 2013;121:4894-901 pubmed publisher |
Choi Y, Yang J, Yusuf I, Johnston R, Greenbaum J, Peters B, et al. Bcl6 expressing follicular helper CD4 T cells are fate committed early and have the capacity to form memory. J Immunol. 2013;190:4014-26 pubmed publisher |
Schilling B, Harasymczuk M, Schuler P, Egan J, Ferrone S, Whiteside T. IRX-2, a novel immunotherapeutic, enhances functions of human dendritic cells. PLoS ONE. 2013;8:e47234 pubmed publisher |
Introini A, Vanpouille C, Lisco A, Grivel J, Margolis L. Interleukin-7 facilitates HIV-1 transmission to cervico-vaginal tissue ex vivo. PLoS Pathog. 2013;9:e1003148 pubmed publisher |
Kuijk L, Verstege M, Rekers N, Bruijns S, Hooijberg E, Roep B, et al. Notch controls generation and function of human effector CD8+ T cells. Blood. 2013;121:2638-46 pubmed publisher |
Mace E, Hsu A, Monaco Shawver L, Makedonas G, Rosen J, Dropulic L, et al. Mutations in GATA2 cause human NK cell deficiency with specific loss of the CD56(bright) subset. Blood. 2013;121:2669-77 pubmed publisher |
Tallerico R, Todaro M, Di Franco S, Maccalli C, Garofalo C, Sottile R, et al. Human NK cells selective targeting of colon cancer-initiating cells: a role for natural cytotoxicity receptors and MHC class I molecules. J Immunol. 2013;190:2381-90 pubmed publisher |
Magnusson M, Sierra M, Sasidharan R, Prashad S, Romero M, Saarikoski P, et al. Expansion on stromal cells preserves the undifferentiated state of human hematopoietic stem cells despite compromised reconstitution ability. PLoS ONE. 2013;8:e53912 pubmed publisher |
Munir S, Fr xf8 sig T, Hansen M, Svane I, Andersen M. Characterization of T-cell responses against IκBα in cancer patients. Oncoimmunology. 2012;1:1290-1296 pubmed |
Amabile G, Welner R, Nombela Arrieta C, D Alise A, Di Ruscio A, Ebralidze A, et al. In vivo generation of transplantable human hematopoietic cells from induced pluripotent stem cells. Blood. 2013;121:1255-64 pubmed publisher |
Cieri N, Camisa B, Cocchiarella F, Forcato M, Oliveira G, Provasi E, et al. IL-7 and IL-15 instruct the generation of human memory stem T cells from naive precursors. Blood. 2013;121:573-84 pubmed publisher |
Testa J, Shetty V, Hafner J, Nickens Z, Kamal S, Sinnathamby G, et al. MHC class I-presented T cell epitopes identified by immunoproteomics analysis are targets for a cross reactive influenza-specific T cell response. PLoS ONE. 2012;7:e48484 pubmed publisher |
van de Laar L, van den Bosch A, Boonstra A, Binda R, Buitenhuis M, Janssen H, et al. PI3K-PKB hyperactivation augments human plasmacytoid dendritic cell development and function. Blood. 2012;120:4982-91 pubmed publisher |
Blix E, Irish J, Husebekk A, Delabie J, Forfang L, Tierens A, et al. Phospho-specific flow cytometry identifies aberrant signaling in indolent B-cell lymphoma. BMC Cancer. 2012;12:478 pubmed publisher |
Demachi Okamura A, Torikai H, Akatsuka Y, Miyoshi H, Yoshimori T, Kuzushima K. Autophagy creates a CTL epitope that mimics tumor-associated antigens. PLoS ONE. 2012;7:e47126 pubmed publisher |
Bilwani F, Knight K. Adipocyte-derived soluble factor(s) inhibits early stages of B lymphopoiesis. J Immunol. 2012;189:4379-86 pubmed publisher |
Patel E, Okada S, Hachey K, Yang L, Durum S, Moreb J, et al. Regulation of in vitro human T cell development through interleukin-7 deprivation and anti-CD3 stimulation. BMC Immunol. 2012;13:46 pubmed publisher |
Cimbro R, Vassena L, Arthos J, Cicala C, Kehrl J, Park C, et al. IL-7 induces expression and activation of integrin α4β7 promoting naive T-cell homing to the intestinal mucosa. Blood. 2012;120:2610-9 pubmed |
Rabenhorst A, Schlaak M, Heukamp L, Förster A, Theurich S, von Bergwelt Baildon M, et al. Mast cells play a protumorigenic role in primary cutaneous lymphoma. Blood. 2012;120:2042-54 pubmed publisher |
Katara G, Ansari N, Singh A, Ramesh V, Salotra P. Evidence for involvement of Th17 type responses in post kala azar dermal leishmaniasis (PKDL). PLoS Negl Trop Dis. 2012;6:e1703 pubmed publisher |
Chang K, Sanchez Aguilera A, Shen S, Sengupta A, Madhu M, Ficker A, et al. Vav3 collaborates with p190-BCR-ABL in lymphoid progenitor leukemogenesis, proliferation, and survival. Blood. 2012;120:800-11 pubmed publisher |
Reimann C, Six E, Dal Cortivo L, Schiavo A, Appourchaux K, Lagresle Peyrou C, et al. Human T-lymphoid progenitors generated in a feeder-cell-free Delta-like-4 culture system promote T-cell reconstitution in NOD/SCID/γc(-/-) mice. Stem Cells. 2012;30:1771-80 pubmed publisher |
Lissauer D, Piper K, Goodyear O, Kilby M, Moss P. Fetal-specific CD8+ cytotoxic T cell responses develop during normal human pregnancy and exhibit broad functional capacity. J Immunol. 2012;189:1072-80 pubmed publisher |
Hoorweg K, Peters C, Cornelissen F, Aparicio Domingo P, Papazian N, Kazemier G, et al. Functional Differences between Human NKp44(-) and NKp44(+) RORC(+) Innate Lymphoid Cells. Front Immunol. 2012;3:72 pubmed publisher |
Liu D, Song L, Wei J, Courtney A, Gao X, Marinova E, et al. IL-15 protects NKT cells from inhibition by tumor-associated macrophages and enhances antimetastatic activity. J Clin Invest. 2012;122:2221-33 pubmed publisher |
Karrich J, Balzarolo M, Schmidlin H, Libouban M, Nagasawa M, Gentek R, et al. The transcription factor Spi-B regulates human plasmacytoid dendritic cell survival through direct induction of the antiapoptotic gene BCL2-A1. Blood. 2012;119:5191-200 pubmed publisher |
Ridges S, Heaton W, Joshi D, Choi H, Eiring A, Batchelor L, et al. Zebrafish screen identifies novel compound with selective toxicity against leukemia. Blood. 2012;119:5621-31 pubmed publisher |
Mitra A, Ross J, Rodriguez G, Nagy Z, Wilson H, Kirken R. Signal transducer and activator of transcription 5b (Stat5b) serine 193 is a novel cytokine-induced phospho-regulatory site that is constitutively activated in primary hematopoietic malignancies. J Biol Chem. 2012;287:16596-608 pubmed publisher |
Tanaka Y, Hayashi M, Kubota Y, Nagai H, Sheng G, Nishikawa S, et al. Early ontogenic origin of the hematopoietic stem cell lineage. Proc Natl Acad Sci U S A. 2012;109:4515-20 pubmed publisher |
Kreft K, Verbraak E, Wierenga Wolf A, van Meurs M, Oostra B, Laman J, et al. The IL-7R? pathway is quantitatively and functionally altered in CD8 T cells in multiple sclerosis. J Immunol. 2012;188:1874-83 pubmed publisher |
Paine A, Kirchner H, Immenschuh S, Oelke M, Blasczyk R, Eiz Vesper B. IL-2 upregulates CD86 expression on human CD4(+) and CD8(+) T cells. J Immunol. 2012;188:1620-9 pubmed publisher |
Sjeklocha L, Park C, Wong P, Roney M, Belcher J, Kaufman D, et al. Erythroid-specific expression of ?-globin from Sleeping Beauty-transduced human hematopoietic progenitor cells. PLoS ONE. 2011;6:e29110 pubmed publisher |
Yu Y, Zitzner J, Houlihan J, Herrera N, Xu L, Miller J, et al. Common gamma chain cytokines promote rapid in vitro expansion of allo-specific human CD8+ suppressor T cells. PLoS ONE. 2011;6:e28948 pubmed publisher |
Chiang C, Hagemann A, Leskowitz R, Mick R, Garrabrant T, Czerniecki B, et al. Day-4 myeloid dendritic cells pulsed with whole tumor lysate are highly immunogenic and elicit potent anti-tumor responses. PLoS ONE. 2011;6:e28732 pubmed publisher |
Sammicheli S, Dang V, Ruffin N, Pham H, Lantto R, Vivar N, et al. IL-7 promotes CD95-induced apoptosis in B cells via the IFN-?/STAT1 pathway. PLoS ONE. 2011;6:e28629 pubmed publisher |
Takata H, Naruto T, Takiguchi M. Functional heterogeneity of human effector CD8+ T cells. Blood. 2012;119:1390-8 pubmed publisher |
Muralidharan S, Hanley P, Liu E, Chakraborty R, Bollard C, Shpall E, et al. Activation of Wnt signaling arrests effector differentiation in human peripheral and cord blood-derived T lymphocytes. J Immunol. 2011;187:5221-32 pubmed publisher |
Chen H, Sun H, You F, Sun W, Zhou X, Chen L, et al. Activation of STAT6 by STING is critical for antiviral innate immunity. Cell. 2011;147:436-46 pubmed publisher |
Bosque A, Famiglietti M, Weyrich A, Goulston C, Planelles V. Homeostatic proliferation fails to efficiently reactivate HIV-1 latently infected central memory CD4+ T cells. PLoS Pathog. 2011;7:e1002288 pubmed publisher |
Park Y, Choi S, Kiesler P, Gil Krzewska A, Borrego F, Weck J, et al. Complex regulation of human NKG2D-DAP10 cell surface expression: opposing roles of the ?c cytokines and TGF-?1. Blood. 2011;118:3019-27 pubmed publisher |
Zhan Y, Zhang Y, Gray D, Carrington E, Bouillet P, Ko H, et al. Defects in the Bcl-2-regulated apoptotic pathway lead to preferential increase of CD25 low Foxp3+ anergic CD4+ T cells. J Immunol. 2011;187:1566-77 pubmed publisher |
Bluteau D, Gilles L, Hilpert M, Antony Debré I, James C, Debili N, et al. Down-regulation of the RUNX1-target gene NR4A3 contributes to hematopoiesis deregulation in familial platelet disorder/acute myelogenous leukemia. Blood. 2011;118:6310-20 pubmed publisher |
Gerdemann U, Vera J, Rooney C, Leen A. Generation of multivirus-specific T cells to prevent/treat viral infections after allogeneic hematopoietic stem cell transplant. J Vis Exp. 2011;: pubmed publisher |
Duy C, Hurtz C, Shojaee S, Cerchietti L, Geng H, Swaminathan S, et al. BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR-ABL1 kinase inhibition. Nature. 2011;473:384-8 pubmed publisher |
Amarnath S, Chen H, Foley J, Costanzo C, Sennesh J, Solomon M, et al. Host-based Th2 cell therapy for prolongation of cardiac allograft viability. PLoS ONE. 2011;6:e18885 pubmed publisher |
Bondanza A, Hambach L, Aghai Z, Nijmeijer B, Kaneko S, Mastaglio S, et al. IL-7 receptor expression identifies suicide gene-modified allospecific CD8+ T cells capable of self-renewal and differentiation into antileukemia effectors. Blood. 2011;117:6469-78 pubmed publisher |
Kurtulus S, Tripathi P, Moreno Fernandez M, Sholl A, Katz J, Grimes H, et al. Bcl-2 allows effector and memory CD8+ T cells to tolerate higher expression of Bim. J Immunol. 2011;186:5729-37 pubmed publisher |
Awong G, Herer E, La Motte Mohs R, Zuniga Pflucker J. Human CD8 T cells generated in vitro from hematopoietic stem cells are functionally mature. BMC Immunol. 2011;12:22 pubmed publisher |
Sun H, Kapuria V, Peterson L, Fang D, Bornmann W, Bartholomeusz G, et al. Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis. Blood. 2011;117:3151-62 pubmed publisher |
Feng N, Vegh P, Rothenberg E, Yui M. Lineage divergence at the first TCR-dependent checkpoint: preferential ?? and impaired ?? T cell development in nonobese diabetic mice. J Immunol. 2011;186:826-37 pubmed publisher |
Janikashvili N, LaCasse C, Larmonier C, Trad M, Herrell A, Bustamante S, et al. Allogeneic effector/memory Th-1 cells impair FoxP3+ regulatory T lymphocytes and synergize with chaperone-rich cell lysate vaccine to treat leukemia. Blood. 2011;117:1555-64 pubmed publisher |
Merlo A, Turrini R, Trento C, Zanovello P, Dolcetti R, Rosato A. Impact of γ-chain cytokines on EBV-specific T cell cultures. J Transl Med. 2010;8:121 pubmed publisher |
S xf8 rensen R, Hadrup S, Svane I, Hjorts xf8 M, thor Straten P, Andersen M. Indoleamine 2,3-dioxygenase specific, cytotoxic T cells as immune regulators. Blood. 2011;117:2200-10 pubmed publisher |
Andersen R, Sørensen R, Ritter C, Svane I, Becker J, thor Straten P, et al. Identification of a cyclin B1-derived CTL epitope eliciting spontaneous responses in both cancer patients and healthy donors. Cancer Immunol Immunother. 2011;60:227-34 pubmed publisher |
Kis L, Gerasimcik N, Salamon D, Persson E, Nagy N, Klein G, et al. STAT6 signaling pathway activated by the cytokines IL-4 and IL-13 induces expression of the Epstein-Barr virus-encoded protein LMP-1 in absence of EBNA-2: implications for the type II EBV latent gene expression in Hodgkin lymphoma. Blood. 2011;117:165-74 pubmed publisher |
Tripathi P, Kurtulus S, Wojciechowski S, Sholl A, Hoebe K, Morris S, et al. STAT5 is critical to maintain effector CD8+ T cell responses. J Immunol. 2010;185:2116-24 pubmed publisher |
Birkholz K, Schwenkert M, Kellner C, Gross S, Fey G, Schuler Thurner B, et al. Targeting of DEC-205 on human dendritic cells results in efficient MHC class II-restricted antigen presentation. Blood. 2010;116:2277-85 pubmed publisher |
Yui M, Feng N, Rothenberg E. Fine-scale staging of T cell lineage commitment in adult mouse thymus. J Immunol. 2010;185:284-93 pubmed publisher |
Martin J, Perry J, Jakhete N, Wang X, Bielekova B. An IL-2 paradox: blocking CD25 on T cells induces IL-2-driven activation of CD56(bright) NK cells. J Immunol. 2010;185:1311-20 pubmed publisher |
Lee S, Yun S, Piao Z, Jeong M, Kim D, Jung H, et al. Suppressor of cytokine signaling 2 regulates IL-15-primed human NK cell function via control of phosphorylated Pyk2. J Immunol. 2010;185:917-28 pubmed publisher |
Guo P, Du M, Wu H, Lin Y, Jin L, Li D. Thymic stromal lymphopoietin from trophoblasts induces dendritic cell-mediated regulatory TH2 bias in the decidua during early gestation in humans. Blood. 2010;116:2061-9 pubmed publisher |
Cella M, Otero K, Colonna M. Expansion of human NK-22 cells with IL-7, IL-2, and IL-1beta reveals intrinsic functional plasticity. Proc Natl Acad Sci U S A. 2010;107:10961-6 pubmed publisher |
Joosten S, van Meijgaarden K, Van Weeren P, Kazi F, Geluk A, Savage N, et al. Mycobacterium tuberculosis peptides presented by HLA-E molecules are targets for human CD8 T-cells with cytotoxic as well as regulatory activity. PLoS Pathog. 2010;6:e1000782 pubmed publisher |
Henriques C, Rino J, Nibbs R, Graham G, Barata J. IL-7 induces rapid clathrin-mediated internalization and JAK3-dependent degradation of IL-7Ralpha in T cells. Blood. 2010;115:3269-77 pubmed publisher |
Sivori S, Falco M, Carlomagno S, Romeo E, Soldani C, Bensussan A, et al. A novel KIR-associated function: evidence that CpG DNA uptake and shuttling to early endosomes is mediated by KIR3DL2. Blood. 2010;116:1637-47 pubmed publisher |
Liang X, Weigand L, Schuster I, Eppinger E, van der Griendt J, Schub A, et al. A single TCR alpha-chain with dominant peptide recognition in the allorestricted HER2/neu-specific T cell repertoire. J Immunol. 2010;184:1617-29 pubmed publisher |
Racanelli V, Leone P, Frassanito M, Brunetti C, Perosa F, Ferrone S, et al. Alterations in the antigen processing-presenting machinery of transformed plasma cells are associated with reduced recognition by CD8+ T cells and characterize the progression of MGUS to multiple myeloma. Blood. 2010;115:1185-93 pubmed publisher |
Peperzak V, Xiao Y, Veraar E, Borst J. CD27 sustains survival of CTLs in virus-infected nonlymphoid tissue in mice by inducing autocrine IL-2 production. J Clin Invest. 2010;120:168-78 pubmed publisher |
Vercoulen Y, Wehrens E, van Teijlingen N, de Jager W, Beekman J, Prakken B. Human regulatory T cell suppressive function is independent of apoptosis induction in activated effector T cells. PLoS ONE. 2009;4:e7183 pubmed publisher |
S xf8 rensen R, Berge Hansen L, Junker N, Hansen C, Hadrup S, Schumacher T, et al. The immune system strikes back: cellular immune responses against indoleamine 2,3-dioxygenase. PLoS ONE. 2009;4:e6910 pubmed publisher |
Centlivre M, Zhou X, Pouw S, Weijer K, Kleibeuker W, Das A, et al. Autoregulatory lentiviral vectors allow multiple cycles of doxycycline-inducible gene expression in human hematopoietic cells in vivo. Gene Ther. 2010;17:14-25 pubmed publisher |
Hagn M, Schwesinger E, Ebel V, Sontheimer K, Maier J, Beyer T, et al. Human B cells secrete granzyme B when recognizing viral antigens in the context of the acute phase cytokine IL-21. J Immunol. 2009;183:1838-45 pubmed publisher |
Eberhard Y, McDermott S, Wang X, Gronda M, Venugopal A, Wood T, et al. Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells. Blood. 2009;114:3064-73 pubmed publisher |
Rayment R, Kooij T, Zhang W, Siebold C, Murphy M, Allen D, et al. Evidence for the specificity for platelet HPA-1a alloepitope and the presenting HLA-DR52a of diverse antigen-specific helper T cell clones from alloimmunized mothers. J Immunol. 2009;183:677-86 pubmed publisher |
Awong G, Herer E, Surh C, Dick J, La Motte Mohs R, Zuniga Pflucker J. Characterization in vitro and engraftment potential in vivo of human progenitor T cells generated from hematopoietic stem cells. Blood. 2009;114:972-82 pubmed publisher |
Xue X, Huang X, Nodland S, Mátés L, Ma L, Izsvák Z, et al. Stable gene transfer and expression in cord blood-derived CD34+ hematopoietic stem and progenitor cells by a hyperactive Sleeping Beauty transposon system. Blood. 2009;114:1319-30 pubmed publisher |
Sawa Y, Arima Y, Ogura H, Kitabayashi C, Jiang J, Fukushima T, et al. Hepatic interleukin-7 expression regulates T cell responses. Immunity. 2009;30:447-57 pubmed publisher |
Sakaguchi M, Kataoka K, Abarzua F, Tanimoto R, Watanabe M, Murata H, et al. Overexpression of REIC/Dkk-3 in normal fibroblasts suppresses tumor growth via induction of interleukin-7. J Biol Chem. 2009;284:14236-44 pubmed publisher |
Henry R, Acevedo Suárez C, Thomas J. Functional silencing is initiated and maintained in immature anti-insulin B cells. J Immunol. 2009;182:3432-9 pubmed publisher |
Nicholls S, Piper K, Mohammed F, Dafforn T, Tenzer S, Salim M, et al. Secondary anchor polymorphism in the HA-1 minor histocompatibility antigen critically affects MHC stability and TCR recognition. Proc Natl Acad Sci U S A. 2009;106:3889-94 pubmed publisher |
Czystowska M, Han J, Szczepanski M, Szajnik M, Quadrini K, Brandwein H, et al. IRX-2, a novel immunotherapeutic, protects human T cells from tumor-induced cell death. Cell Death Differ. 2009;16:708-18 pubmed publisher |
Lundberg K, Roos A, Pavlenko M, Leder C, Wehrum D, Guevara Pati xf1 o J, et al. A modified epitope identified for generation and monitoring of PSA-specific T cells in patients on early phases of PSA-based immunotherapeutic protocols. Vaccine. 2009;27:1557-65 pubmed publisher |
Ahlen M, Husebekk A, Killie M, Skogen B, Stuge T. T-cell responses associated with neonatal alloimmune thrombocytopenia: isolation of HPA-1a-specific, HLA-DRB3*0101-restricted CD4+ T cells. Blood. 2009;113:3838-44 pubmed publisher |
Nijmeijer B, Szuhai K, Goselink H, van Schie M, van der Burg M, de Jong D, et al. Long-term culture of primary human lymphoblastic leukemia cells in the absence of serum or hematopoietic growth factors. Exp Hematol. 2009;37:376-85 pubmed publisher |
Symes J, Siatskas C, Fowler D, Medin J. Retrovirally transduced murine T lymphocytes expressing FasL mediate effective killing of prostate cancer cells. Cancer Gene Ther. 2009;16:439-52 pubmed publisher |
Figueiredo C, Wittmann M, Wang D, Dressel R, Seltsam A, Blasczyk R, et al. Heat shock protein 70 (HSP70) induces cytotoxicity of T-helper cells. Blood. 2009;113:3008-16 pubmed publisher |
Carreno B, Becker Hapak M, Linette G. CD40 regulates human dendritic cell-derived IL-7 production that, in turn, contributes to CD8(+) T-cell antigen-specific expansion. Immunol Cell Biol. 2009;87:167-77 pubmed publisher |
Kaneko S, Mastaglio S, Bondanza A, Ponzoni M, Sanvito F, Aldrighetti L, et al. IL-7 and IL-15 allow the generation of suicide gene-modified alloreactive self-renewing central memory human T lymphocytes. Blood. 2009;113:1006-15 pubmed publisher |
Li C, Wu H, Yan H, Ma S, Wang L, Zhang M, et al. T cell responses to whole SARS coronavirus in humans. J Immunol. 2008;181:5490-500 pubmed |
Su Z, Frye C, Bae K, Kelley V, Vieweg J. Differentiation of human embryonic stem cells into immunostimulatory dendritic cells under feeder-free culture conditions. Clin Cancer Res. 2008;14:6207-17 pubmed publisher |
Skowera A, Ellis R, Varela Calvi xf1 o R, Arif S, Huang G, Van Krinks C, et al. CTLs are targeted to kill beta cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope. J Clin Invest. 2008;118:3390-402 pubmed publisher |
Ter Brake O, Legrand N, von Eije K, Centlivre M, Spits H, Weijer K, et al. Evaluation of safety and efficacy of RNAi against HIV-1 in the human immune system (Rag-2(-/-)gammac(-/-)) mouse model. Gene Ther. 2009;16:148-53 pubmed publisher |
Awong G, La Motte Mohs R, Z xfa xf1 iga Pfl xfc cker J. In vitro human T cell development directed by notch-ligand interactions. Methods Mol Biol. 2008;430:135-42 pubmed publisher |
Sakuishi K, Oki S, Araki M, Porcelli S, Miyake S, Yamamura T. Invariant NKT cells biased for IL-5 production act as crucial regulators of inflammation. J Immunol. 2007;179:3452-62 pubmed |
Bauer A, Villunger A, Labi V, Fischer S, Strasser A, Wagner H, et al. The NF-kappaB regulator Bcl-3 and the BH3-only proteins Bim and Puma control the death of activated T cells. Proc Natl Acad Sci U S A. 2006;103:10979-84 pubmed |
van Beek J, van Meurs M, t Hart B, Brok H, Neal J, Chatagner A, et al. Decay-accelerating factor (CD55) is expressed by neurons in response to chronic but not acute autoimmune central nervous system inflammation associated with complement activation. J Immunol. 2005;174:2353-65 pubmed |
Lin L, Gerth A, Peng S. Active inhibition of plasma cell development in resting B cells by microphthalmia-associated transcription factor. J Exp Med. 2004;200:115-22 pubmed |
Hemminki A, Kanerva A, Liu B, Wang M, Alvarez R, Siegal G, et al. Modulation of coxsackie-adenovirus receptor expression for increased adenoviral transgene expression. Cancer Res. 2003;63:847-53 pubmed |
