PCNA (Proliferating Cell Nuclear Antigen) Mouse Monoclonal Antibody (clone PC10), Concentrate

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PCNA (Proliferating Cell Nuclear Antigen) Mouse Monoclonal Antibody (clone PC10), Concentrate

catalog :

180110

quantity :

1 ml

clonality :

monoclonal

host :

mouse

clone name :

PC10

reactivity :

hamsters, Pacific oyster, budgerigar, human, mouse, rat, pig, zebrafish , rabbit

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 47

Published Application/Species/Dilution	Reference
immunocytochemistry; human; fig 5	Klee S, Lehmann M, Wagner D, Baarsma H, Konigshoff M. WISP1 mediates IL-6-dependent proliferation in primary human lung fibroblasts. Sci Rep. 2016;6:20547 pubmed publisher
immunohistochemistry - paraffin section; rat; fig s3	Gat-Yablonski G, Finka A, Pinto G, Quadroni M, Shtaif B, Goloubinoff P. Quantitative proteomics of rat livers shows that unrestricted feeding is stressful for proteostasis with implications on life span. Aging (Albany NY). 2016;8:1735-58 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:300; fig 3 western blot; mouse; 1:1000; fig 3	Lin X, Xu W, Shao M, Fan Q, Wen G, Li C, et al. Shenling Baizhu San supresses colitis associated colorectal cancer through inhibition of epithelial-mesenchymal transition and myeloid-derived suppressor infiltration. BMC Complement Altern Med. 2015;15:126 pubmed publisher
immunohistochemistry - paraffin section; rat; fig 1, 2	Campos-Silva P, Furriel A, Costa W, Sampaio F, Gregorio B. Metabolic and testicular effects of the long-term administration of different high-fat diets in adult rats. Int Braz J Urol. 2015;41:569-75 pubmed publisher
immunohistochemistry; human; 1:500; fig 7	Pollack D, Xiao Y, Shrivasatava V, Levy A, Andrusier M, D'Armiento J, et al. CDK14 expression is down-regulated by cigarette smoke in vivo and in vitro. Toxicol Lett. 2015;234:120-30 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:200	Pozzi A, Wary K, Giancotti F, Gardner H. Integrin alpha1beta1 mediates a unique collagen-dependent proliferation pathway in vivo. J Cell Biol. 1998;142:587-94 pubmed
immunohistochemistry - paraffin section; rat; 1:200; fig 4	Alves-Pereira J, Colli S, Marques D, Sampaio F, Ramos C. Molecular and morphometric analysis of the rat ventral prostate injected with leptin. Regul Pept. 2012;176:6-12 pubmed publisher
immunohistochemistry - paraffin section; rat western blot; rat	Dusso A, Pavlopoulos T, Naumovich L, Lu Y, Finch J, Brown A, et al. p21(WAF1) and transforming growth factor-alpha mediate dietary phosphate regulation of parathyroid cell growth. Kidney Int. 2001;59:855-65 pubmed
immunohistochemistry - paraffin section; rabbit; fig 3	Wen Q, Jin D, Zhou C, Zhou M, Luo W, Ma L. HGF-transgenic MSCs can improve the effects of tissue self-repair in a rabbit model of traumatic osteonecrosis of the femoral head. PLoS ONE. 2012;7:e37503 pubmed publisher
immunohistochemistry; human; 1:400; tbl 1	Li M, Zhang Q, Liu L, Lu W, Wei H, Li R, et al. Expression of the mismatch repair gene hMLH1 is enhanced in non-small cell lung cancer with EGFR mutations. PLoS ONE. 2013;8:e78500 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:10; fig 1	Sayi A, Kohler E, Hitzler I, Arnold I, Schwendener R, Rehrauer H, et al. The CD4+ T cell-mediated IFN-gamma response to Helicobacter infection is essential for clearance and determines gastric cancer risk. J Immunol. 2009;182:7085-101 pubmed publisher
immunohistochemistry - paraffin section; rat	Ritter C, Finch J, Slatopolsky E, Brown A. Parathyroid hyperplasia in uremic rats precedes down-regulation of the calcium receptor. Kidney Int. 2001;60:1737-44 pubmed
flow cytometry; human	Naora H, Gougeon M. Interleukin-15 is a potent survival factor in the prevention of spontaneous but not CD95-induced apoptosis in CD4 and CD8 T lymphocytes of HIV-infected individuals. Correlation with its ability to increase BCL-2 expression. Cell Death Differ. 1999;6:1002-11 pubmed
immunohistochemistry - paraffin section; budgerigar; 1:100	Striedter G, Charvet C. Developmental origins of species differences in telencephalon and tectum size: morphometric comparisons between a parakeet (Melopsittacus undulatus) and a quail (Colinus virgianus). J Comp Neurol. 2008;507:1663-75 pubmed publisher
immunohistochemistry - paraffin section; human; 1:200; fig 1	Yakirevich E, Maroun L, Cohen O, Izhak O, Rennert G, Resnick M. Apoptosis, proliferation, and Fas (APO-1, CD95)/Fas ligand expression in medullary carcinoma of the breast. J Pathol. 2000;192:166-73 pubmed
western blot; human; fig 2	Baydoun H, Pancewicz J, Bai X, Nicot C. HTLV-I p30 inhibits multiple S phase entry checkpoints, decreases cyclin E-CDK2 interactions and delays cell cycle progression. Mol Cancer. 2010;9:302 pubmed publisher
immunoprecipitation; human; fig 3e	Klaile E, Müller M, Kannicht C, Otto W, Singer B, Reutter W, et al. The cell adhesion receptor carcinoembryonic antigen-related cell adhesion molecule 1 regulates nucleocytoplasmic trafficking of DNA polymerase delta-interacting protein 38. J Biol Chem. 2007;282:26629-40 pubmed
immunohistochemistry - paraffin section; mouse; fig 1	Craig V, Arnold I, Gerke C, Huynh M, Wündisch T, Neubauer A, et al. Gastric MALT lymphoma B cells express polyreactive, somatically mutated immunoglobulins. Blood. 2010;115:581-91 pubmed publisher
western blot; human; 1:400; fig 2	Chimploy K, Díaz G, Li Q, Carter O, Dashwood W, Mathews C, et al. E2F4 and ribonucleotide reductase mediate S-phase arrest in colon cancer cells treated with chlorophyllin. Int J Cancer. 2009;125:2086-94 pubmed publisher
western blot; mouse; 1:100; fig 3	Lu Q, Xin Y, Ye F, Foulks G, Li Q. 14-3-3σ controls corneal epithelium homeostasis and wound healing. Invest Ophthalmol Vis Sci. 2011;52:2389-96 pubmed publisher
immunocytochemistry; human	Gupta V, Bhasin S, Guo W, Singh R, Miki R, Chauhan P, et al. Effects of dihydrotestosterone on differentiation and proliferation of human mesenchymal stem cells and preadipocytes. Mol Cell Endocrinol. 2008;296:32-40 pubmed publisher
immunohistochemistry - paraffin section; rat; 1:100; tbl 1	Fuller T, Rose F, Singleton K, Linde Y, Hoff U, Freise C, et al. Glutamine donor pretreatment in rat kidney transplants with severe preservation reperfusion injury. J Surg Res. 2007;140:77-83 pubmed
immunohistochemistry - paraffin section; human; fig 2	Liu X, Aigner A, Wellstein A, Ray P. Up-regulation of a fibroblast growth factor binding protein in children with renal diseases. Kidney Int. 2001;59:1717-28 pubmed
immunohistochemistry - paraffin section; human; 1:4000; fig 4	Chang K, Huang X, Medeiros L, Jones D. Germinal centre-like versus undifferentiated stromal immunophenotypes in follicular lymphoma. J Pathol. 2003;201:404-12 pubmed
immunohistochemistry; mouse	Nesslein L, Melton K, Ikegami M, Na C, Wert S, Rice W, et al. Partial SP-B deficiency perturbs lung function and causes air space abnormalities. Am J Physiol Lung Cell Mol Physiol. 2005;288:L1154-61 pubmed
immunohistochemistry - paraffin section; mouse; 1:200; fig 2	Li Q, Sambandam S, Lu H, Thomson A, Kim S, Lu H, et al. 14-3-3σ and p63 play opposing roles in epidermal tumorigenesis. Carcinogenesis. 2011;32:1782-8 pubmed publisher
immunohistochemistry - paraffin section; human	Yang B, Ma C, Chen Z, Yi W, McNutt M, Wang Y, et al. Correlation of immunoglobulin G expression and histological subtype and stage in breast cancer. PLoS ONE. 2013;8:e58706 pubmed publisher
western blot; rat; 1:300; fig 4	Li R, Strykowski R, Meyer M, Mulcrone P, Krakora D, Suzuki M. Male-specific differences in proliferation, neurogenesis, and sensitivity to oxidative stress in neural progenitor cells derived from a rat model of ALS. PLoS ONE. 2012;7:e48581 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:1500	Cabello C, Bair W, Lamore S, Ley S, Bause A, Azimian S, et al. The cinnamon-derived Michael acceptor cinnamic aldehyde impairs melanoma cell proliferation, invasiveness, and tumor growth. Free Radic Biol Med. 2009;46:220-31 pubmed publisher
immunohistochemistry - frozen section; zebrafish ; 1:150; fig 4	Maurer C, Schonthaler H, Mueller K, Neuhauss S. Distinct retinal deficits in a zebrafish pyruvate dehydrogenase-deficient mutant. J Neurosci. 2010;30:11962-72 pubmed publisher
immunohistochemistry - paraffin section; human; 1:400; fig 1	Li M, Liu L, Wang Z, Wang L, Liu Z, Xu G, et al. Overexpression of hMSH2 and hMLH1 protein in certain gastric cancers and their surrounding mucosae. Oncol Rep. 2008;19:401-6 pubmed
immunohistochemistry - frozen section; mouse; fig 5	Marose T, Merkel C, McMahon A, Carroll T. Beta-catenin is necessary to keep cells of ureteric bud/Wolffian duct epithelium in a precursor state. Dev Biol. 2008;314:112-26 pubmed publisher
immunohistochemistry; human; 1:50	Cao Y, Zhang M, Wang J, Zhang W, Li G, Zhao J. Recurrent intracranial hemangiopericytoma with multiple metastases. Chin Med J (Engl). 2006;119:169-73 pubmed
immunohistochemistry - paraffin section; pig; 1:100	Southgate K, Mehta D, Izzat M, Newby A, Angelini G. Increased secretion of basement membrane-degrading metalloproteinases in pig saphenous vein into carotid artery interposition grafts. Arterioscler Thromb Vasc Biol. 1999;19:1640-9 pubmed
immunohistochemistry - paraffin section; human; fig 1 immunohistochemistry - paraffin section; mouse; fig 1	Ray P, Tassi E, Liu X, Wellstein A. Role of fibroblast growth factor-binding protein in the pathogenesis of HIV-associated hemolytic uremic syndrome. Am J Physiol Regul Integr Comp Physiol. 2006;290:R105-13 pubmed
immunohistochemistry; human; fig 2	Zhang C, Gurevich I, Aneskievich B. Organotypic modeling of human keratinocyte response to peroxisome proliferators. Cells Tissues Organs. 2012;196:431-41 pubmed publisher
immunohistochemistry - paraffin section; human	Hammoud Z, Badve S, Saxena R, Kesler K, Rieger K, Malkas L, et al. A novel biomarker for the detection of esophageal adenocarcinoma. J Thorac Cardiovasc Surg. 2007;133:82-7 pubmed
immunohistochemistry; pig; tbl 3	Bracarense A, Yamasaki L, Silva E, Oliveira R, Alfieri A. Helicobacter spp. infection induces changes in epithelial proliferation and E-cadherin expression in the gastric mucosa of pigs. J Comp Pathol. 2013;149:402-9 pubmed publisher
immunohistochemistry; human; 1:40; fig 1	Bar-Shira Maymon B, Yogev L, Yavetz H, Lifschitz-Mercer B, Schreiber L, Kleiman S, et al. Spermatogonial proliferation patterns in men with azoospermia of different etiologies. Fertil Steril. 2003;80:1175-80 pubmed
immunohistochemistry - paraffin section; mouse; 1:10; fig 3	Mueller A, O'rourke J, Chu P, Chu A, Dixon M, Bouley D, et al. The role of antigenic drive and tumor-infiltrating accessory cells in the pathogenesis of helicobacter-induced mucosa-associated lymphoid tissue lymphoma. Am J Pathol. 2005;167:797-812 pubmed
immunoprecipitation; hamsters; fig 3 western blot; hamsters; fig 1	Naryzhny S, Lee H. The post-translational modifications of proliferating cell nuclear antigen: acetylation, not phosphorylation, plays an important role in the regulation of its function. J Biol Chem. 2004;279:20194-9 pubmed
immunohistochemistry - paraffin section; pig; 2 ug/ml; fig 3	Masters R, Crean B, Yan W, Moss A, Ryan P, Wiley A, et al. Neonatal porcine endometrial development and epithelial proliferation affected by age and exposure to estrogen and relaxin. Domest Anim Endocrinol. 2007;33:335-46 pubmed
immunohistochemistry - paraffin section; mouse	Ritter C, Martin D, Lu Y, Slatopolsky E, Brown A. Reversal of secondary hyperparathyroidism by phosphate restriction restores parathyroid calcium-sensing receptor expression and function. J Bone Miner Res. 2002;17:2206-13 pubmed
immunohistochemistry - paraffin section; Pacific oyster; 1:100 western blot; Pacific oyster; 1:500	Franco A, Jouaux A, Mathieu M, Sourdaine P, Lelong C, Kellner K, et al. Proliferating cell nuclear antigen in gonad and associated storage tissue of the Pacific oyster Crassostrea gigas: seasonal immunodetection and expression in laser microdissected tissues. Cell Tissue Res. 2010;340:201-10 pubmed publisher
immunohistochemistry - paraffin section; pig; 1:100; fig 4	Fu X, Fang L, Li H, Li X, Cheng B, Sheng Z. Adipose tissue extract enhances skin wound healing. Wound Repair Regen. 2007;15:540-8 pubmed
	Wang J, Liu L, Brinton R. Estradiol-17beta-induced human neural progenitor cell proliferation is mediated by an estrogen receptor beta-phosphorylated extracellularly regulated kinase pathway. Endocrinology. 2008;149:208-18 pubmed
	Leze E, Alves-Pereira J, Colli S, Cavalcante F, José Sampaio F, da Fonte Ramos C. Leptin regulates proliferation and apoptosis in human prostate. ScientificWorldJournal. 2012;2012:842301 pubmed publisher

product information

SKU :

180110

Name :

PCNA (Proliferating Cell Nuclear Antigen) Mouse Monoclonal Antibody (clone PC10), Concentrate

Product Type 2 :

Primary Antibodies

Product Type 3 :

Protein Specific Primary Antibodies

Antibody Conjugate :

Unconjugated

Host :

Mouse

Clonality :

Monoclonal

SubClass (Isotype) :

IgG2a

Label Type :

Unconjugated

Label or Dye :

Unconjugated

Target Gene :

PCNA (Proliferating Cell Nuclear Antigen)

Reactivity :

Human Insect Mouse Primate Rat Yeast

Validated Application :

Immunohistochemistry (FFPE)

Regulatory Statement :

For In Vitro Diagnostic Use.

Product Size :

1 ml

ContentsAndStorage :

Store in refrigerator (2 8 C).