CD278 (ICOS) Monoclonal Antibody (C398.4A), APC, eBioscience | Invitrogen 17-9949-80 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD278 (ICOS) Monoclonal Antibody (C398.4A), APC, eBioscience

catalog :

17-9949-80

quantity :

25 µg

price :

US 121

clonality :

monoclonal

host :

hamsters

conjugate :

APC

clone name :

C398.4A

reactivity :

mouse, rat, rhesus macaque

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 4d	Shi B, Geng J, Wang Y, Wei H, Walters B, Li W, et al. Foxp1 Negatively Regulates T Follicular Helper Cell Differentiation and Germinal Center Responses by Controlling Cell Migration and CTLA-4. J Immunol. 2018;200:586-594 pubmed publisher
	Yu L, Zhou B, Zhu Y, Li L, Zhong Y, Zhu L, et al. HSF1 promotes CD69+ Treg differentiation to inhibit colitis progression. Theranostics. 2023;13:1892-1905 pubmed publisher
	O Neill T, Gewies A, Seeholzer T, Krappmann D. TRAF6 controls T cell homeostasis by maintaining the equilibrium of MALT1 scaffolding and protease functions. Front Immunol. 2023;14:1111398 pubmed publisher
	Jowett G, Read E, Roberts L, Coman D, Vil xe0 Gonz xe1 lez M, Zabinski T, et al. Organoids capture tissue-specific innate lymphoid cell development in mice and humans. Cell Rep. 2022;40:111281 pubmed publisher
	Robles Valero J, Fern xe1 ndez Nevado L, Cuadrado M, Lorenzo Mart xed n L, Fern xe1 ndez Pisonero I, Abad A, et al. Characterization of the spectrum of trivalent VAV1-mutation-driven tumours using a gene-edited mouse model. Mol Oncol. 2022;16:3533-3553 pubmed publisher
	Robles Valero J, Fernandez Nevado L, Lorenzo Martín L, Cuadrado M, Fernández Pisonero I, Rodríguez Fdez S, et al. Cancer-associated mutations in VAV1 trigger variegated signaling outputs and T-cell lymphomagenesis. EMBO J. 2021;40:e108125 pubmed publisher
	Krisna S, Goncalves C, Gagnon N, Huang F, Plourde D, Miller W, et al. Optimized protocol for immunophenotyping of melanoma and tumor-bearing skin from mouse. STAR Protoc. 2021;2:100627 pubmed publisher
	Leech J, Dhariwala M, Lowe M, Chu K, Merana G, Cornuot C, et al. Toxin-Triggered Interleukin-1 Receptor Signaling Enables Early-Life Discrimination of Pathogenic versus Commensal Skin Bacteria. Cell Host Microbe. 2019;26:795-809.e5 pubmed publisher
	Knolle M, Chin S, Rana B, Englezakis A, Nakagawa R, Fallon P, et al. MicroRNA-155 Protects Group 2 Innate Lymphoid Cells From Apoptosis to Promote Type-2 Immunity. Front Immunol. 2018;9:2232 pubmed publisher
	Rezende R, Lanser A, Rubino S, Kuhn C, Skillin N, Moreira T, et al. γδ T cells control humoral immune response by inducing T follicular helper cell differentiation. Nat Commun. 2018;9:3151 pubmed publisher
	Cho S, Lee H, Yu I, Choi Y, Huang H, Hashemifar S, et al. Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146b. Nat Commun. 2018;9:2757 pubmed publisher
	Hao Y, Wang Y, Liu X, Yang X, Wang P, Tian Q, et al. The Kinase Complex mTOR Complex 2 Promotes the Follicular Migration and Functional Maturation of Differentiated Follicular Helper CD4+ T Cells During Viral Infection. Front Immunol. 2018;9:1127 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD278 (ICOS) Monoclonal Antibody (C398.4A), APC, eBioscience

Catalog # :

17-9949-80

Quantity :

25 µg

Price :

US 121

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Armenian Hamster

Reactivity :

Mouse, Rat, Rhesus Monkey

Applications :

Flow Cytometry: 0.125 µg/test

Species :

Mouse, Rat, Rhesus Monkey

Clone :

C398.4A

Isotype :

IgG

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

ICOS (CD278) encodes a protein that is a member of the CD28 and CTLA-4 cell-surface receptor family. It functions as a homodimer and has a crucial role in cell-cell signaling, immune responses, and the regulation of cell proliferation. ICOS has been linked to various disorders, including Immunodeficiency, Common Variable, 1 and Common Variable Immunodeficiency.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.125 µg/test

Aliases :

Activation-inducible lymphocyte immunomediatory molecule; Ailim; CCLP; CD278; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; CVID1; H4; Icos; inducible costimulator; inducible T cell costimulator; inducible T cell co-stimulator; inducible T-cell costimulator; inducible T-cell co-stimulator; Ly115

more info or order :

Invitrogen product webpage