GARP Monoclonal Antibody (YGIC86), APC, eBioscience | Invitrogen 17-9891-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GARP Monoclonal Antibody (YGIC86), APC, eBioscience

catalog :

17-9891-82

quantity :

100 ug

price :

US 442.00

clonality :

monoclonal

host :

rat

conjugate :

APC

clone name :

YGIC86

reactivity :

mouse

application :

flow cytometry

citations: 15

Reference
Araujo Furlan C, Tosello Boari J, Rodríguez C, Canale F, Fiocca Vernengo F, Boccardo S, et al. Limited Foxp3+ Regulatory T Cells Response During Acute Trypanosoma cruzi Infection Is Required to Allow the Emergence of Robust Parasite-Specific CD8+ T Cell Immunity. Front Immunol. 2018;9:2555 pubmed publisher
Zhong Y, Tang H, Wang X, Zeng Q, Liu Y, Zhao X, et al. Intranasal immunization with heat shock protein 60 induces CD4(+) CD25(+) GARP(+) and type 1 regulatory T cells and inhibits early atherosclerosis. Clin Exp Immunol. 2016;183:452-68 pubmed publisher
Zhao X, Liu Y, Zhong Y, Liu B, Yu K, Shi H, et al. Atorvastatin Improves Inflammatory Response in Atherosclerosis by Upregulating the Expression of GARP. Mediators Inflamm. 2015;2015:841472 pubmed publisher
Carrillo Galvez A, Cobo M, Cuevas OcaÃ±a S, GutiÃ©rrez Guerrero A, SÃ¡nchez Gilabert A, Bongarzone P, et al. Mesenchymal stromal cells express GARP/LRRC32 on their surface: effects on their biology and immunomodulatory capacity. Stem Cells. 2015;33:183-95 pubmed publisher
Edwards J, Fujii H, Zhou A, Creemers J, Unutmaz D, Shevach E. Regulation of the expression of GARP/latent TGF-Î²1 complexes on mouse T cells and their role in regulatory T cell and Th17 differentiation. J Immunol. 2013;190:5506-15 pubmed publisher
van der Marel S, Majowicz A, Kwikkers K, van Logtenstein R, te Velde A, De Groot A, et al. Adeno-associated virus mediated delivery of Tregitope 167 ameliorates experimental colitis. World J Gastroenterol. 2012;18:4288-99 pubmed publisher
Kofler D, Chmielewski M, Rappl G, Hombach A, Riet T, Schmidt A, et al. CD28 costimulation Impairs the efficacy of a redirected t-cell antitumor attack in the presence of regulatory t cells which can be overcome by preventing Lck activation. Mol Ther. 2011;19:760-7 pubmed publisher
Oida T, Weiner H. TGF-? induces surface LAP expression on murine CD4 T cells independent of Foxp3 induction. PLoS ONE. 2010;5:e15523 pubmed publisher
Oida T, Weiner H. Overexpression of TGF-ß 1 gene induces cell surface localized glucose-regulated protein 78-associated latency-associated peptide/TGF-ß. J Immunol. 2010;185:3529-35 pubmed publisher
Wang R, Kozhaya L, Mercer F, Khaitan A, Fujii H, Unutmaz D. Expression of GARP selectively identifies activated human FOXP3+ regulatory T cells. Proc Natl Acad Sci U S A. 2009;106:13439-44 pubmed publisher
Tran D, Andersson J, Wang R, Ramsey H, Unutmaz D, Shevach E. GARP (LRRC32) is essential for the surface expression of latent TGF-beta on platelets and activated FOXP3+ regulatory T cells. Proc Natl Acad Sci U S A. 2009;106:13445-50 pubmed publisher
Wang R, Wan Q, Kozhaya L, Fujii H, Unutmaz D. Identification of a regulatory T cell specific cell surface molecule that mediates suppressive signals and induces Foxp3 expression. PLoS ONE. 2008;3:e2705 pubmed publisher
Macaulay I, Tijssen M, Thijssen Timmer D, Gusnanto A, Steward M, Burns P, et al. Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins. Blood. 2007;109:3260-9 pubmed
Roubin R, Pizette S, Ollendorff V, Planche J, Birnbaum D, Delapeyriere O. Structure and developmental expression of mouse Garp, a gene encoding a new leucine-rich repeat-containing protein. Int J Dev Biol. 1996;40:545-55 pubmed
Ollendorff V, Noguchi T, Delapeyriere O, Birnbaum D. The GARP gene encodes a new member of the family of leucine-rich repeat-containing proteins. Cell Growth Differ. 1994;5:213-9 pubmed

product information

Product Type :

Antibody

Product Name :

GARP Monoclonal Antibody (YGIC86), APC, eBioscience

Catalog # :

17-9891-82

Quantity :

100 ug

Price :

US 442.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.125 ug/test

Species :

Mouse

Clone :

YGIC86

Isotype :

IgG2a, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

GARP, also known as leucine rich repeat containing 32, is a type I membrane protein with twenty-two leucine-rich repeats and a short intracytoplasmic region. GARP was identified based on the analysis of gene expression profiling of Treg and Th cells following TCR stimulation. Since GARP is expressed in CD4+, CD25+, FoxP3+ cells (Tregs), it may be a candidate for cell surface marker for Treg cells.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.125 ug/test

Aliases :

AI426318; D11S833E; D11S833Eh; D7H11S833E; EG434215; Garp; garpin; Glycoprotein A repetitions predominant; leucine rich repeat containing 32; leucine-rich repeat-containing protein 32; Lrrc32; Transforming growth factor beta activator LRRC32