This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD289 (TLR9) Monoclonal Antibody (eB72-1665), APC, eBioscience
catalog :
17-9099-82
quantity :
100 ug
price :
US 471.00
clonality :
monoclonal
host :
rat
conjugate :
APC
clone name :
eB72-1665

The same clone is also sold as:
reactivity :
human
application :
flow cytometry
citations: 30
Reference
Splunter M, Perdijk O, Fick Brinkhof H, Floris Vollenbroek E, Meijer B, Brugman S, et al. Plasmacytoid dendritic cell and myeloid dendritic cell function in ageing: A comparison between elderly and young adult women. PLoS ONE. 2019;14:e0225825 pubmed publisher
Tobouti P, BOLT R, Radhakrishnan R, de Sousa S, Hunter K. Altered Toll-like receptor expression and function in HPV-associated oropharyngeal carcinoma. Oncotarget. 2018;9:236-248 pubmed publisher
El Kebir D, Damlaj A, Filep J. Toll-like receptor 9 signaling delays neutrophil apoptosis by increasing transcription of Mcl-1. PLoS ONE. 2014;9:e87006 pubmed publisher
Bratke K, Prieschenk C, Garbe K, Kuepper M, Lommatzsch M, Virchow J. Plasmacytoid dendritic cells in allergic asthma and the role of inhaled corticosteroid treatment. Clin Exp Allergy. 2013;43:312-21 pubmed publisher
Freeman C, Martinez F, Han M, Washko G, McCubbrey A, Chensue S, et al. Lung CD8+ T cells in COPD have increased expression of bacterial TLRs. Respir Res. 2013;14:13 pubmed publisher
Fierro M, Banche G, Marenco F, Novelli M, Allizond V, Mandras N, et al. Functional and phenotypical impairment of polymorphonuclear cells in atopic dermatitis: an additional cause for the known susceptibility to infections?. Dermatology. 2012;224:323-30 pubmed publisher
Garbe K, Bratke K, Wagner S, Virchow J, Lommatzsch M. Plasmacytoid dendritic cells and their Toll-like receptor 9 expression selectively decrease with age. Hum Immunol. 2012;73:493-7 pubmed publisher
Fierro M, Cuffini A, Novelli M, Banche G, Allizond V, Comessatti A, et al. Functional and phenotypical alterations of polymorphonuclear cells in Sézary syndrome patients. Eur J Dermatol. 2011;21:921-9 pubmed publisher
Dasari P, Zola H, Nicholson I. Expression of Toll-like receptors by neonatal leukocytes. Pediatr Allergy Immunol. 2011;22:221-8 pubmed publisher
Bratke K, Klein C, Kuepper M, Lommatzsch M, Virchow J. Differential development of plasmacytoid dendritic cells in Th1- and Th2-like cytokine milieus. Allergy. 2011;66:386-95 pubmed publisher
Llinàs L, Lázaro A, de Salort J, Matesanz Isabel J, Sintes J, Engel P. Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry. Immunol Lett. 2011;134:113-21 pubmed publisher
Cabezón R, Sintes J, Llinàs L, Benitez Ribas D. Analysis of HLDA9 mAbs on plasmacytoid dendritic cells. Immunol Lett. 2011;134:167-73 pubmed publisher
Kiemer A, Senaratne R, Hoppstädter J, Diesel B, Riley L, Tabeta K, et al. Attenuated activation of macrophage TLR9 by DNA from virulent mycobacteria. J Innate Immun. 2009;1:29-45 pubmed publisher
Liu F, Li G, Wen K, Bui T, Cao D, Zhang Y, et al. Porcine small intestinal epithelial cell line (IPEC-J2) of rotavirus infection as a new model for the study of innate immune responses to rotaviruses and probiotics. Viral Immunol. 2010;23:135-49 pubmed publisher
Neves P, Matos D, Marcovistz R, Galler R. TLR expression and NK cell activation after human yellow fever vaccination. Vaccine. 2009;27:5543-9 pubmed publisher
Zorro S, Arias M, Riano F, Paris S, Ramirez L, Uribe O, et al. Response to ODN-CpG by B Cells from patients with systemic lupus erythematosus correlates with disease activity. Lupus. 2009;18:718-26 pubmed publisher
Martín Martín L, Almeida J, Hernández Campo P, Sanchez M, Lecrevisse Q, Orfao A. Immunophenotypical, morphologic, and functional characterization of maturation-associated plasmacytoid dendritic cell subsets in normal adult human bone marrow. Transfusion. 2009;49:1692-1708 pubmed publisher
El Kebir D, Jozsef L, Pan W, Wang L, Filep J. Bacterial DNA activates endothelial cells and promotes neutrophil adherence through TLR9 signaling. J Immunol. 2009;182:4386-94 pubmed publisher
Wen K, Azevedo M, Gonzalez A, Zhang W, Saif L, Li G, et al. Toll-like receptor and innate cytokine responses induced by lactobacilli colonization and human rotavirus infection in gnotobiotic pigs. Vet Immunol Immunopathol. 2009;127:304-15 pubmed publisher
Peiser M, Koeck J, Kirschning C, Wittig B, Wanner R. Human Langerhans cells selectively activated via Toll-like receptor 2 agonists acquire migratory and CD4+T cell stimulatory capacity. J Leukoc Biol. 2008;83:1118-27 pubmed publisher
Loharungsikul S, Troye Blomberg M, Amoudruz P, Pichyangkul S, Yongvanitchit K, Looareesuwan S, et al. Expression of toll-like receptors on antigen-presenting cells in patients with falciparum malaria. Acta Trop. 2008;105:10-5 pubmed
Peduzzi E, Groeper C, Schütte D, Zajac P, Rondini S, Mensah Quainoo E, et al. Local activation of the innate immune system in Buruli ulcer lesions. J Invest Dermatol. 2007;127:638-45 pubmed
Leifer C, Brooks J, Hoelzer K, Lopez J, Kennedy M, Mazzoni A, et al. Cytoplasmic targeting motifs control localization of toll-like receptor 9. J Biol Chem. 2006;281:35585-92 pubmed
Jozsef L, Khreiss T, El Kebir D, Filep J. Activation of TLR-9 induces IL-8 secretion through peroxynitrite signaling in human neutrophils. J Immunol. 2006;176:1195-202 pubmed
Schroeder J, Bieneman A, Xiao H, Chichester K, Vasagar K, Saini S, et al. TLR9- and FcepsilonRI-mediated responses oppose one another in plasmacytoid dendritic cells by down-regulating receptor expression. J Immunol. 2005;175:5724-31 pubmed
Dasari P, Nicholson I, Hodge G, Dandie G, Zola H. Expression of toll-like receptors on B lymphocytes. Cell Immunol. 2005;236:140-5 pubmed
Droemann D, Albrecht D, Gerdes J, Ulmer A, Branscheid D, Vollmer E, et al. Human lung cancer cells express functionally active Toll-like receptor 9. Respir Res. 2005;6:1 pubmed
Platz J, Beisswenger C, Dalpke A, Koczulla R, Pinkenburg O, Vogelmeier C, et al. Microbial DNA induces a host defense reaction of human respiratory epithelial cells. J Immunol. 2004;173:1219-23 pubmed
Leifer C, Kennedy M, Mazzoni A, Lee C, Kruhlak M, Segal D. TLR9 is localized in the endoplasmic reticulum prior to stimulation. J Immunol. 2004;173:1179-83 pubmed
Latz E, Schoenemeyer A, Visintin A, Fitzgerald K, Monks B, Knetter C, et al. TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nat Immunol. 2004;5:190-8 pubmed
product information
Product Type :
Antibody
Product Name :
CD289 (TLR9) Monoclonal Antibody (eB72-1665), APC, eBioscience
Catalog # :
17-9099-82
Quantity :
100 ug
Price :
US 471.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Human
Applications :
Flow Cytometry: 1 ug/test
Species :
Human
Clone :
eB72-1665
Isotype :
IgG2a, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
The protein encoded by this gene is a member of the Toll-like receptor family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1 ug/test
Aliases :
CD289; Tlr9; toll like receptor 9; toll-like receptor 9; UNQ5798/PRO19605
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA