CD217 (IL-17Ra) Monoclonal Antibody (PAJ-17R), APC, eBioscience | Invitrogen 17-7182-80 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD217 (IL-17Ra) Monoclonal Antibody (PAJ-17R), APC, eBioscience

catalog :

17-7182-80

quantity :

25 ug

price :

US 174.00

clonality :

monoclonal

host :

rat

conjugate :

APC

clone name :

PAJ-17R

reactivity :

mouse

application :

flow cytometry

citations: 8

Reference
Calcinotto A, Brevi A, Chesi M, Ferrarese R, Garcia Perez L, Grioni M, et al. Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression. Nat Commun. 2018;9:4832 pubmed publisher
Giles D, Moreno Fernandez M, Stankiewicz T, Cappelletti M, Huppert S, Iwakura Y, et al. Regulation of Inflammation by IL-17A and IL-17F Modulates Non-Alcoholic Fatty Liver Disease Pathogenesis. PLoS ONE. 2016;11:e0149783 pubmed publisher
Chukkapalli S, Velsko I, Rivera Kweh M, Zheng D, Lucas A, Kesavalu L. Polymicrobial Oral Infection with Four Periodontal Bacteria Orchestrates a Distinct Inflammatory Response and Atherosclerosis in ApoE null Mice. PLoS ONE. 2015;10:e0143291 pubmed publisher
Hamour S, Gan P, Pepper R, Florez Barros F, Wang H, O Sullivan K, et al. Local IL-17 Production Exerts a Protective Role in Murine Experimental Glomerulonephritis. PLoS ONE. 2015;10:e0136238 pubmed publisher
Chukkapalli S, Rivera Kweh M, Velsko I, Chen H, Zheng D, Bhattacharyya I, et al. Chronic oral infection with major periodontal bacteria Tannerella forsythia modulates systemic atherosclerosis risk factors and inflammatory markers. Pathog Dis. 2015;73: pubmed publisher
Chen S, Shimada K, Zhang W, Huang G, Crother T, Arditi M. IL-17A is proatherogenic in high-fat diet-induced and Chlamydia pneumoniae infection-accelerated atherosclerosis in mice. J Immunol. 2010;185:5619-27 pubmed publisher
Toy D, Kugler D, Wolfson M, Vanden Bos T, Gurgel J, Derry J, et al. Cutting edge: interleukin 17 signals through a heteromeric receptor complex. J Immunol. 2006;177:36-9 pubmed
Tan W, Huang W, Zhong Q, Schwarzenberger P. IL-17 receptor knockout mice have enhanced myelotoxicity and impaired hemopoietic recovery following gamma irradiation. J Immunol. 2006;176:6186-93 pubmed

product information

Product Type :

Antibody

Product Name :

CD217 (IL-17Ra) Monoclonal Antibody (PAJ-17R), APC, eBioscience

Catalog # :

17-7182-80

Quantity :

25 ug

Price :

US 174.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.25 ug/test

Species :

Mouse

Clone :

PAJ-17R

Isotype :

IgG2a

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F. IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 ug/test

Aliases :

AW538159; CANDF5; CD127; CD217; CDw217; hIL-17R; IL-17 receptor A; IL17R; Il17ra; IL-17RA; interleukin 17 receptor A; interleukin-17 receptor A; MGC10262; VDw217