MHC Class II Monoclonal Antibody (YKIX334.2), APC, eBioscience | Invitrogen 17-5909-42 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MHC Class II Monoclonal Antibody (YKIX334.2), APC, eBioscience

catalog :

17-5909-42

quantity :

100 Tests

price :

US 334

clonality :

monoclonal

host :

rat

conjugate :

APC

clone name :

YKIX334.2

reactivity :

dogs

application :

flow cytometry

citations: 5

Reference
Pantelyushin S, Ranninger E, Guerrera D, Hutter G, Maake C, Markkanen E, et al. Cross-Reactivity and Functionality of Approved Human Immune Checkpoint Blockers in Dogs. Cancers (Basel). 2021;13: pubmed publisher
Bismarck D, Schütze N, Moore P, Büttner M, Alber G, Buttlar H. Canine CD4+CD8+ double positive T cells in peripheral blood have features of activated T cells. Vet Immunol Immunopathol. 2012;149:157-66 pubmed publisher
Rabanal R, Ferrer L, Else R. Immunohistochemical detection of canine leucocyte antigens by specific monoclonal antibodies in canine normal tissues. Vet Immunol Immunopathol. 1995;47:13-23 pubmed
Cobbold S, Metcalfe S. Monoclonal antibodies that define canine homologues of human CD antigens: summary of the First International Canine Leukocyte Antigen Workshop (CLAW). Tissue Antigens. 1994;43:137-54 pubmed
Doveren R, van Der Linden C, Spronken E, Groenewegen G, Buurman W. Canine MHC-class II antigens on B and T lymphocytes. Tissue Antigens. 1986;27:87-98 pubmed

product information

Product Type :

Antibody

Product Name :

MHC Class II Monoclonal Antibody (YKIX334.2), APC, eBioscience

Catalog # :

17-5909-42

Quantity :

100 Tests

Price :

US 334

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Canine

Applications :

Flow Cytometry: 5 µL (0.25 µg)/test

Species :

Canine

Clone :

YKIX334.2

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells, such as macrophages, dendritic cells and B cells. Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to the T cells. The antigen-binding grove between MHC class II alpha and beta chain is open at both ends and is 15-24 amino acid residues long. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 µL (0.25 µg)/test

Aliases :

beta 1 domain; B-L; B-L beta chain; B-L beta minor; B-LB; BLB major; BLB1; BLB2; B-LB2; B-LB21; B-LB21 major; BLB3; Bl-Beta II protein; B-LBII; class II histocompatibility antigen, B-L beta chain; class II histocompatibility antigen, M alpha chain; D6S222E; DMA; FECA-DRB; GSP-BLB1; GSP-BLB2; HLA class II histocompatibility antigen, DM alpha chain; HLADM; HLA-DMA; major histocompatibility class II antigen B-L beta; major histocompatibility complex class II B; Major histocompatibility complex class II beta chain BLB1; Major histocompatibility complex class II beta chain BLB1, (similar to HLA class II, D beta chain); major histocompatibility complex class II beta chain BLB1, (similar to HLA class II, D beta chain); Major histocompatibility complex class II beta chain BLB2, (similar to HLA class II, D beta chain); Major histocompatibility complex class II beta chain BLB3, (similar to HLA class II, D beta chain); major histocompatibility complex, class II, DM alpha; MHC 2; MHC Class II; MHC class II antigen; MHC class II antigen beta chain; MHC class II antigen B-F minor heavy chain; MHC class II antigen DMA; MHC class II antigen DRB; MHC Class II beta 1 and 2 domains; MHC class II beta 1 domain; MHC class II beta chain; MHC class II beta chain 1; MHC class II beta chain 2; MHC class II B-L beta chain; MHC II; MHCCII; MHCFECA-DRB; really interesting new gene 6 protein; RING6; S19; uncharacterized protein LOC101747454