product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
VSIG4 Monoclonal Antibody (NLA14), APC, eBioscience
catalog :
17-5752-82
quantity :
100 µg
price :
US 377
clonality :
monoclonal
host :
rat
conjugate :
APC
clone name :
NLA14
reactivity :
human, mouse
application :
flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 9
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...
Goncalves S, Yin K, Ito Y, Chan A, Olan I, Gough S, et al. COX2 regulates senescence secretome composition and senescence surveillance through PGE2. Cell Rep. 2021;34:108860 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 1a, s1a
  • flow cytometry; mouse; loading ...; fig 2b
  • immunohistochemistry - frozen section; human; 1:100; loading ...; fig 1b
Luo Z, Ji Y, Gao H, Gomes Dos Reis F, Bandyopadhyay G, Jin Z, et al. CRIg+ Macrophages Prevent Gut Microbial DNA-Containing Extracellular Vesicle-Induced Tissue Inflammation and Insulin Resistance. Gastroenterology. 2021;160:863-874 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s6a
Hall B, Gleiberman A, Strom E, Krasnov P, Frescas D, Vujcic S, et al. Immune checkpoint protein VSIG4 as a biomarker of aging in murine adipose tissue. Aging Cell. 2020;19:e13219 pubmed publisher
Gao H, Jin Z, Tang K, Ji Y, Suarez J, Suarez J, et al. Microbial DNA Enrichment Promotes Adrenomedullary Inflammation, Catecholamine Secretion, and Hypertension in Obese Mice. J Am Heart Assoc. 2022;11:e024561 pubmed publisher
Gao H, Luo Z, Ji Y, Tang K, Jin Z, Ly C, et al. Accumulation of microbial DNAs promotes to islet inflammation and β cell abnormalities in obesity in mice. Nat Commun. 2022;13:565 pubmed publisher
Guilliams M, Bonnardel J, Haest B, Vanderborght B, Wagner C, Remmerie A, et al. Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches. Cell. 2022;185:379-396.e38 pubmed publisher
Daemen S, Chan M, Schilling J. Comprehensive analysis of liver macrophage composition by flow cytometry and immunofluorescence in murine NASH. STAR Protoc. 2021;2:100511 pubmed publisher
Daemen S, Gainullina A, Kalugotla G, He L, Chan M, Beals J, et al. Dynamic Shifts in the Composition of Resident and Recruited Macrophages Influence Tissue Remodeling in NASH. Cell Rep. 2021;34:108626 pubmed publisher
Zheng F, Luo S, Ouyang Z, Zhou J, Mo H, Schoonooghe S, et al. NIRF-Molecular Imaging with Synovial Macrophages-Targeting Vsig4 Nanobody for Disease Monitoring in a Mouse Model of Arthritis. Int J Mol Sci. 2019;20: pubmed publisher
product information
Product Type :
Antibody
Product Name :
VSIG4 Monoclonal Antibody (NLA14), APC, eBioscience
Catalog # :
17-5752-82
Quantity :
100 µg
Price :
US 377
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.5 µg/test
Species :
Mouse
Clone :
NLA14
Isotype :
IgG2a, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
T cell activation by APCs is positively and negatively regulated by members of the B7 family. VSIG4 is a strong negative regulator of murine and human T cell proliferation and IL-2 production.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.5 µg/test
Aliases :
A530061A11; BC025105; complement receptor of the immunoglobulin superfamily; CRIg; Ig superfamily protein; MGC137243 protein; protein Z39Ig; UNQ317/PRO362; V-set and immunoglobulin domain containing 4; V-set and immunoglobulin domain-containing protein 4; VSIG4; Z39IG
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA