Ki-67 Monoclonal Antibody (20Raj1), APC, eBioscience | Invitrogen 17-5699-41 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Ki-67 Monoclonal Antibody (20Raj1), APC, eBioscience

catalog :

17-5699-41

quantity :

25 Tests

price :

US 188.00

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

20Raj1

reactivity :

human, dogs

application :

flow cytometry

citations: 12

Reference
Cascone T, Leung C, Weissferdt A, Pataer A, Carter B, Godoy M, et al. Neoadjuvant chemotherapy plus nivolumab with or without ipilimumab in operable non-small cell lung cancer: the phase 2 platform NEOSTAR trial. Nat Med. 2023;29:593-604 pubmed publisher
Ye L, Peng W, Niu Y, Xiang X, Wei X, Wang Z, et al. Accumulation of TNFR2-expressing regulatory T cells in malignant pleural effusion of lung cancer patients is associated with poor prognosis. Ann Transl Med. 2020;8:1647 pubmed publisher
Gaudreau P, Negrao M, Mitchell K, Reuben A, Corsini E, Li J, et al. Neoadjuvant Chemotherapy Increases Cytotoxic T Cell, Tissue Resident Memory T Cell, and B Cell Infiltration in Resectable NSCLC. J Thorac Oncol. 2021;16:127-139 pubmed publisher
Wang L, Ai Z, Khoyratty T, Zec K, Eames H, van Grinsven E, et al. ROS-producing immature neutrophils in giant cell arteritis are linked to vascular pathologies. JCI Insight. 2020;5: pubmed publisher
Li L, Mei H, Commey A. Application of RNA-sequencing to identify transcriptome modification by DCLK1 in colorectal cancer cells. Cancer Gene Ther. 2020;27:691-701 pubmed publisher
Dawson N, Lamarche C, Hoeppli R, Bergqvist P, Fung V, McIver E, et al. Systematic testing and specificity mapping of alloantigen-specific chimeric antigen receptors in regulatory T cells. JCI Insight. 2019;4: pubmed publisher
Nguyen H, Noguchi S, Sugie K, Matsuo Y, Nguyen C, Koito H, et al. Small-Vessel Vasculopathy Due to Aberrant Autophagy in LAMP-2 Deficiency. Sci Rep. 2018;8:3326 pubmed publisher
de Alwis R, Bangs D, Angelo M, Cerpas C, Fernando A, Sidney J, et al. Immunodominant Dengue Virus-Specific CD8+ T Cell Responses Are Associated with a Memory PD-1+ Phenotype. J Virol. 2016;90:4771-4779 pubmed publisher
Bikker A, Kruize A, van der Wurff Jacobs K, Peters R, Kleinjan M, Redegeld F, et al. Interleukin-7 and Toll-like receptor 7 induce synergistic B cell and T cell activation. PLoS ONE. 2014;9:e94756 pubmed publisher
Jiao Y, Hua W, Zhang T, Zhang Y, Ji Y, Zhang H, et al. Characteristics of CD8+ T cell subsets in Chinese patients with chronic HIV infection during initial ART. AIDS Res Ther. 2011;8:15 pubmed publisher
Schluter C, Duchrow M, Wohlenberg C, Becker M, Key G, Flad H, et al. The cell proliferation-associated antigen of antibody Ki-67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins. J Cell Biol. 1993;123:513-22 pubmed
Gerdes J, Lemke H, Baisch H, Wacker H, Schwab U, Stein H. Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J Immunol. 1984;133:1710-5 pubmed

product information

Product Type :

Antibody

Product Name :

Ki-67 Monoclonal Antibody (20Raj1), APC, eBioscience

Catalog # :

17-5699-41

Quantity :

25 Tests

Price :

US 188.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Canine, Human

Applications :

Flow Cytometry: 5 uL (0.25 ug)/test

Species :

Canine, Human

Clone :

20Raj1

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during late G1, S, G2, and M phases. The protein has a forkhead associated domain (FHA) through which it associates with euchromatin at the perichromosomal layer, the centromeric heterochromatin, and the nucleolus. Ki-67 is shown to have a cell cycle dependent topographical distribution with perinucleolar expression at G1, expression in the nuclear matrix at G2, and expression on the chromosomes during M phase. Ki-67 is commonly used as a proliferation marker because it is not detected in G0 cells, but increases steadily from G1 through mitosis. Ki-67 antibodies are useful in establishing the cell growing fraction in neoplasms. In neoplastic tissues, the prognostic value is comparable to the tritiated thymidine-labelling index. The correlation between low Ki-67 index and histologically low-grade tumors is strong. Ki-67 is routinely used as a neuronal marker of cell cycling and proliferation.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (0.25 ug)/test

Aliases :

antigen identified by monoclonal antibody Ki 67; antigen identified by monoclonal antibody Ki-67; Antigen identified by monoclonal antibody Ki-67 homolog; Antigen KI-67; Antigen KI-67 homolog; antigen KI-67; proliferation marker protein Ki-67; antigen KI-67-like; cb31; D630048A14Rik; I79_022666; Ki67; Ki-67; KIA; LOW QUALITY PROTEIN: proliferation marker protein Ki-67; marker of proliferation Ki-67; MIB-; MIB-1; Mki67; PPP1R105; Proliferation marker protein Ki-67; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105; RP11-380J17.2; sb:cb31; si:ch211-250b22.7; unnamed protein product; wu:fa11g09; wu:fb57a07; wu:fi14e05