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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Ki-67 Monoclonal Antibody (SolA15), APC, eBioscience
catalog :
17-5698-80
quantity :
25 ug
price :
US 175.00
clonality :
monoclonal
host :
rat
conjugate :
APC
clone name :
SolA15
reactivity :
crab eating macaque, human, mouse, rat, dogs
application :
flow cytometry
more info or order :
citations: 28
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 6b
Ying L, Zhang M, Ma X, Si Y, Li X, Su J, et al. Macrophage LAMTOR1 Deficiency Prevents Dietary Obesity and Insulin Resistance Through Inflammation-Induced Energy Expenditure. Front Cell Dev Biol. 2021;9:672032 pubmed publisher
Capellmann S, Sonntag R, Sch xfc ler H, Meurer S, Gan L, Kauffmann M, et al. Transformation of primary murine peritoneal mast cells by constitutive KIT activation is accompanied by loss of Cdkn2a/Arf expression. Front Immunol. 2023;14:1154416 pubmed publisher
Wang C, Wu Y, Li Y, Zhang Y, Fung Y, Tong K, et al. Smad4-mediated angiogenesis facilitates the beiging of white adipose tissue in mice. iScience. 2023;26:106272 pubmed publisher
Lo W, Kuhlmann M, Rizzuto G, Ekiz H, Kolawole E, Revelo M, et al. A single-amino acid substitution in the adaptor LAT accelerates TCR proofreading kinetics and alters T-cell selection, maintenance and function. Nat Immunol. 2023;24:676-689 pubmed publisher
Peauroi E, Carro S, Pei L, Reynoso G, Hickman H, Eisenlohr L. The ectromelia virus virulence factor C15 facilitates early viral spread by inhibiting NK cell contact. iScience. 2022;25:105510 pubmed publisher
L xf3 pez D, Apostol A, Lebish E, Valencia C, Romero Mulero M, Pavlovich P, et al. Prenatal inflammation perturbs murine fetal hematopoietic development and causes persistent changes to postnatal immunity. Cell Rep. 2022;41:111677 pubmed publisher
Schloss M, Hulsmans M, Rohde D, Lee I, Severe N, Foy B, et al. B lymphocyte-derived acetylcholine limits steady-state and emergency hematopoiesis. Nat Immunol. 2022;23:605-618 pubmed publisher
Ganan Gomez I, Yang H, Ma F, Montalban Bravo G, Thongon N, Marchica V, et al. Stem cell architecture drives myelodysplastic syndrome progression and predicts response to venetoclax-based therapy. Nat Med. 2022;28:557-567 pubmed publisher
Bangs D, Tsitsiklis A, Steier Z, Chan S, Kaminski J, STREETS A, et al. CXCR3 regulates stem and proliferative CD8+ T cells during chronic infection by promoting interactions with DCs in splenic bridging channels. Cell Rep. 2022;38:110266 pubmed publisher
Schmid V, Khadour A, Ahmed N, Brandl C, Nitschke L, Rajewsky K, et al. B cell antigen receptor expression and phosphatidylinositol 3-kinase signaling regulate genesis and maintenance of mouse chronic lymphocytic leukemia. Haematologica. 2022;: pubmed publisher
Wahida A, Müller M, Hiergeist A, Popper B, Steiger K, Branca C, et al. XIAP restrains TNF-driven intestinal inflammation and dysbiosis by promoting innate immune responses of Paneth and dendritic cells. Sci Immunol. 2021;6:eabf7235 pubmed publisher
Fu J, Shih L, Yen T. HOXA11 plays critical roles in disease progression and response to cytarabine in AML. Oncol Rep. 2021;46: pubmed publisher
Zhu B, Wu Y, Huang S, Zhang R, Son Y, Li C, et al. Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infection. Immunity. 2021;54:1200-1218.e9 pubmed publisher
Todorovic Z, Milovanovic J, Arsenijevic D, Vukovic N, Vukic M, Arsenijević A, et al. Shikonin Derivatives from Onsoma visianii Decrease Expression of Phosphorylated STAT3 in Leukemia Cells and Exert Antitumor Activity. Nutrients. 2021;13: pubmed publisher
Fujino T, Goyama S, Sugiura Y, Inoue D, Asada S, Yamasaki S, et al. Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway. Nat Commun. 2021;12:1826 pubmed publisher
Suzuki S, McCarrey J, Hermann B. An mTORC1-dependent switch orchestrates the transition between mouse spermatogonial stem cells and clones of progenitor spermatogonia. Cell Rep. 2021;34:108752 pubmed publisher
Budhu S, Giese R, Gupta A, Fitzgerald K, Zappasodi R, Schad S, et al. Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma. Cell Rep. 2021;34:108620 pubmed publisher
Kuhn N, Lopez A, Li X, Cai W, Daniyan A, Brentjens R. CD103+ cDC1 and endogenous CD8+ T cells are necessary for improved CD40L-overexpressing CAR T cell antitumor function. Nat Commun. 2020;11:6171 pubmed publisher
Wu R, Ma F, Tosevska A, Farrell C, Pellegrini M, Deb A. Cardiac fibroblast proliferation rates and collagen expression mature early and are unaltered with advancing age. JCI Insight. 2020;5: pubmed publisher
Rodrigues T, Alvarez A, Gembre A, Forni M, de Melo B, Alves Filho J, et al. Mycobacterium tuberculosis-infected alveolar epithelial cells modulate dendritic cell function through the HIF-1α-NOS2 axis. J Leukoc Biol. 2020;108:1225-1238 pubmed publisher
Wagner J, Wong P, Schappe T, Berrien Elliott M, Cubitt C, Jaeger N, et al. Stage-Specific Requirement for Eomes in Mature NK Cell Homeostasis and Cytotoxicity. Cell Rep. 2020;31:107720 pubmed publisher
Riedel R, Addo R, Ferreira Gomes M, Heinz G, Heinrich F, Kummer J, et al. Discrete populations of isotype-switched memory B lymphocytes are maintained in murine spleen and bone marrow. Nat Commun. 2020;11:2570 pubmed publisher
Gladow N, Hollmann C, Ramos G, Frantz S, Kerkau T, Beyersdorf N, et al. Treatment of mice with a ligand binding blocking anti-CD28 monoclonal antibody improves healing after myocardial infarction. PLoS ONE. 2020;15:e0227734 pubmed publisher
Cong L, Bai Z, Du Y, Cheng Y. Citron Rho-Interacting Serine/Threonine Kinase Promotes HIF1a-CypA Signaling and Growth of Human Pancreatic Adenocarcinoma. Biomed Res Int. 2020;2020:9210891 pubmed publisher
Hurrell B, Galle Treger L, Jahani P, Howard E, Helou D, Banie H, et al. TNFR2 Signaling Enhances ILC2 Survival, Function, and Induction of Airway Hyperreactivity. Cell Rep. 2019;29:4509-4524.e5 pubmed publisher
Li Q, Li D, Zhang X, Wan Q, Zhang W, Zheng M, et al. E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor. Immunity. 2018;48:258-270.e5 pubmed publisher
Ghoneim H, Fan Y, Moustaki A, Abdelsamed H, Dash P, Dogra P, et al. De Novo Epigenetic Programs Inhibit PD-1 Blockade-Mediated T Cell Rejuvenation. Cell. 2017;170:142-157.e19 pubmed publisher
Povinelli B, Nemeth M. Wnt5a regulates hematopoietic stem cell proliferation and repopulation through the Ryk receptor. Stem Cells. 2014;32:105-15 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Ki-67 Monoclonal Antibody (SolA15), APC, eBioscience
Catalog # :
17-5698-80
Quantity :
25 ug
Price :
US 175.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Canine, Cynomolgus Monkey, Human, Mouse, Non-human primate, Rat
Applications :
Flow Cytometry: 0.06 ug
Species :
Canine, Cynomolgus Monkey, Human, Mouse, Non-human primate, Rat
Clone :
SolA15
Isotype :
IgG2a, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during late G1, S, G2, and M phases. The protein has a forkhead associated domain (FHA) through which it associates with euchromatin at the perichromosomal layer, the centromeric heterochromatin, and the nucleolus. Ki-67 is shown to have a cell cycle dependent topographical distribution with perinucleolar expression at G1, expression in the nuclear matrix at G2, and expression on the chromosomes during M phase. Ki-67 is commonly used as a proliferation marker because it is not detected in G0 cells, but increases steadily from G1 through mitosis. Ki-67 antibodies are useful in establishing the cell growing fraction in neoplasms. In neoplastic tissues, the prognostic value is comparable to the tritiated thymidine-labelling index. The correlation between low Ki-67 index and histologically low-grade tumors is strong. Ki-67 is routinely used as a neuronal marker of cell cycling and proliferation.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.06 ug
Aliases :
antigen identified by monoclonal antibody Ki 67; antigen identified by monoclonal antibody Ki-67; Antigen identified by monoclonal antibody Ki-67 homolog; Antigen KI-67; Antigen KI-67 homolog; antigen KI-67; proliferation marker protein Ki-67; antigen KI-67-like; cb31; D630048A14Rik; I79_022666; Ki67; Ki-67; KIA; LOW QUALITY PROTEIN: proliferation marker protein Ki-67; marker of proliferation Ki-67; MIB-; MIB-1; Mki67; PPP1R105; Proliferation marker protein Ki-67; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105; RP11-380J17.2; sb:cb31; si:ch211-250b22.7; unnamed protein product; wu:fa11g09; wu:fb57a07; wu:fi14e05
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA