CD85g (ILT7) Monoclonal Antibody (eBio17G10.2 (17G10.2)), APC, eBioscience™ | Invitrogen 17-5179-42 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD85g (ILT7) Monoclonal Antibody (eBio17G10.2 (17G10.2)), APC, eBioscience™

catalog :

17-5179-42

quantity :

100 Tests

price :

US 313

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

eBio17G10.2 (17G10.2)

reactivity :

human

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; tbl .S2	Ruffell B, Au A, Rugo H, Esserman L, Hwang E, Coussens L. Leukocyte composition of human breast cancer. Proc Natl Acad Sci U S A. 2012;109:2796-801 pubmed publisher
	Tavano B, Galao R, Graham D, Neil S, Aquino V, Fuchs D, et al. Ig-like transcript 7, but not bone marrow stromal cell antigen 2 (also known as HM1.24, tetherin, or CD317), modulates plasmacytoid dendritic cell function in primary human blood leukocytes. J Immunol. 2013;190:2622-30 pubmed publisher
	Cao W, Rosen D, Ito T, Bover L, Bao M, Watanabe G, et al. Plasmacytoid dendritic cell-specific receptor ILT7-Fc epsilonRI gamma inhibits Toll-like receptor-induced interferon production. J Exp Med. 2006;203:1399-405 pubmed
	Ju X, Hacker C, Scherer B, Redecke V, Berger T, Schuler G, et al. Immunoglobulin-like transcripts ILT2, ILT3 and ILT7 are expressed by human dendritic cells and down-regulated following activation. Gene. 2004;331:159-64 pubmed
	Rissoan M, Duhen T, Bridon J, Bendriss Vermare N, Peronne C, de Saint Vis B, et al. Subtractive hybridization reveals the expression of immunoglobulin-like transcript 7, Eph-B1, granzyme B, and 3 novel transcripts in human plasmacytoid dendritic cells. Blood. 2002;100:3295-303 pubmed

product information

Product Type :

Antibody

Product Name :

CD85g (ILT7) Monoclonal Antibody (eBio17G10.2 (17G10.2)), APC, eBioscience™

Catalog # :

17-5179-42

Quantity :

100 Tests

Price :

US 313

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 µL (0.25 µg)/test

Species :

Human

Clone :

eBio17G10.2 (17G10.2)

Isotype :

IgG1

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

ILT7 is a pDC-specific IgG-like transcript and is a member of the leukocyte immunoglobulin-like receptor gene family. This receptor, in complex with FcER1a, transduces ITAM-mediated signals which negatively modulate type I IFN production by pDC. ILT7 is thus a potential target to regulate Type 1 IFN production by pDC, which play a major role during viral infection, auto-immune diseases and anti-cancer immunity. Additionally, ILT7, along with CD123 and BDCA-2, can be used to identify or classify subsets of pDCalong with TLR expression and TLR mediated immune responses.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 µL (0.25 µg)/test

Aliases :

CD85 antigen-like family member G; CD85g; ILT7; ILT-7; Immunoglobulin-like transcript 7; leucocyte Ig-like receptor A4; leukocyte immunoglobulin like receptor A4; leukocyte immunoglobulin-like receptor subfamily A member 4; leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4; leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 4; LILRA4

more info or order :

Invitrogen product webpage