product summary
Loading...
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD85k (ILT3) Monoclonal Antibody (ZM4.1), APC, eBioscience™
catalog :
17-5139-42
quantity :
100 Tests
price :
US 373
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
ZM4.1
reactivity :
human
application :
flow cytometry
more info or order :
Invitrogen product webpage
citations: 4
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; 1:100; loading ...; fig 1g
Deng M, Gui X, Kim J, Xie L, Chen W, Li Z, et al. LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration. Nature. 2018;562:605-609 pubmed publisher
Su R, Dong L, Li Y, Gao M, Han L, Wunderlich M, et al. Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion. Cancer Cell. 2020;38:79-96.e11 pubmed publisher
Penna G, Roncari A, Amuchastegui S, Daniel K, Berti E, Colonna M, et al. Expression of the inhibitory receptor ILT3 on dendritic cells is dispensable for induction of CD4+Foxp3+ regulatory T cells by 1,25-dihydroxyvitamin D3. Blood. 2005;106:3490-7 pubmed
Cella M, Döhring C, Samaridis J, Dessing M, Brockhaus M, Lanzavecchia A, et al. A novel inhibitory receptor (ILT3) expressed on monocytes, macrophages, and dendritic cells involved in antigen processing. J Exp Med. 1997;185:1743-51 pubmed
product information
Product Type :
Antibody
Product Name :
CD85k (ILT3) Monoclonal Antibody (ZM4.1), APC, eBioscience™
Catalog # :
17-5139-42
Quantity :
100 Tests
Price :
US 373
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 5 µL (0.125 µg)/test
Species :
Human
Clone :
ZM4.1
Isotype :
IgG1, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 5 µL (0.125 µg)/test
Aliases :
CD85 antigen-like family member K; CD85k; glycoprotein 49 B; glycoprotein 49b; gp49; Gp49b; GP49B2; HM18; ILT3; ILT-3; Immunoglobulin-like transcript 3; leucocyte Ig-like receptor B4; leukocyte immunoglobulin like receptor B4; leukocyte immunoglobulin-like receptor 5; Leukocyte immunoglobulin-like receptor subfamily B member 4; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4; leukocyte immunoglobulin-like receptor, subfamily B, member 4; leukocyte surface receptor; Lilrb4; LIR5; LIR-5; Mast cell surface glycoprotein Gp49B; monocyte inhibitory receptor HM18
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA