CD8a Monoclonal Antibody (YCATE55.9), APC, eBioscience™ | Invitrogen 17-5080-41 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD8a Monoclonal Antibody (YCATE55.9), APC, eBioscience™

catalog :

17-5080-41

quantity :

25Tests

price :

US 117

clonality :

monoclonal

host :

rat

conjugate :

APC

clone name :

YCATE55.9

reactivity :

dogs

application :

flow cytometry

citations: 5

Reference
Bismarck D, Schütze N, Moore P, Büttner M, Alber G, Buttlar H. Canine CD4+CD8+ double positive T cells in peripheral blood have features of activated T cells. Vet Immunol Immunopathol. 2012;149:157-66 pubmed publisher
Lin Y, Huang Y, Wang Y, Juang R, Liao K, Chu R. Canine CD8 T cells showing NK cytotoxic activity express mRNAs for NK cell-associated surface molecules. Vet Immunol Immunopathol. 2010;133:144-53 pubmed publisher
Elwood C, Hamblin A, Batt R. Quantitative and qualitative immunohistochemistry of T cell subsets and MHC class II expression in the canine small intestine. Vet Immunol Immunopathol. 1997;58:195-207 pubmed
Cobbold S, Metcalfe S. Monoclonal antibodies that define canine homologues of human CD antigens: summary of the First International Canine Leukocyte Antigen Workshop (CLAW). Tissue Antigens. 1994;43:137-54 pubmed
Watson C, Cobbold S, Davies H, Rebello P, Thiru S, McNair R, et al. Immunosuppression of canine renal allograft recipients by CD4 and CD8 monoclonal antibodies. Tissue Antigens. 1994;43:155-62 pubmed

product information

Product Type :

Antibody

Product Name :

CD8a Monoclonal Antibody (YCATE55.9), APC, eBioscience™

Catalog # :

17-5080-41

Quantity :

25Tests

Price :

US 117

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Canine

Applications :

Flow Cytometry: 5 µL (0.5 µg)/test

Species :

Canine

Clone :

YCATE55.9

Isotype :

IgG1, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

CD8 (Cluster of Differentiation 8) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediate efficient cell-cell interactions within the immune system. The CD8 antigen acts as a co-receptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. CD8 is found on a T cell subset of normal cytotoxic/suppressor cells which make up approximately 20-35 % of human peripheral blood lymphocytes. The CD8 antigen is also detected on natural killer (NK) cells, subpopulations of peripheral blood null cells, thymocytes and bone marrow cells. The CD8 co-receptor functions as either a homodimer composed of two alpha chains, or as a disulfide-linked heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. The majority of CD8+ T cells express CD8 as a alpha/beta heterodimer. In HIV, the HIV-2 envelope glycoprotein binds CD8 alpha chain (but not the beta chain).

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 µL (0.5 µg)/test

Aliases :

CD8, Leu-2, MAL, p32, CD8a