This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
BrdU Monoclonal Antibody (BU20A), APC, eBioscience
catalog :
17-5071-41
quantity :
25 Tests
price :
US 164.00
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
Bu20a
application :
flow cytometry
citations: 40
Reference
Wang C, Wu Y, Li Y, Zhang Y, Fung Y, Tong K, et al. Smad4-mediated angiogenesis facilitates the beiging of white adipose tissue in mice. iScience. 2023;26:106272 pubmed publisher
Kurani H, Razavipour S, Harikumar K, Dunworth M, Ewald A, Nasir A, et al. DOT1L Is a Novel Cancer Stem Cell Target for Triple-Negative Breast Cancer. Clin Cancer Res. 2022;28:1948-1965 pubmed publisher
Wilmore J, Gaudette B, G xf3 mez Atria D, Rosenthal R, Reiser S, Meng W, et al. IgA Plasma Cells Are Long-Lived Residents of Gut and Bone Marrow That Express Isotype- and Tissue-Specific Gene Expression Patterns. Front Immunol. 2021;12:791095 pubmed publisher
McAlpine C, Park J, Griciuc A, Kim E, Choi S, Iwamoto Y, et al. Astrocytic interleukin-3 programs microglia and limits Alzheimer's disease. Nature. 2021;595:701-706 pubmed publisher
Ghosh S, Nataraj N, Noronha A, Patkar S, Sekar A, Mukherjee S, et al. PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR. Cell Rep. 2021;35:109181 pubmed publisher
Nakata S, Yuan M, Rubens J, Kahlert U, Maciaczyk J, Raabe E, et al. BCOR Internal Tandem Duplication Expression in Neural Stem Cells Promotes Growth, Invasion, and Expression of PRC2 Targets. Int J Mol Sci. 2021;22: pubmed publisher
Yu V, So S, Lung M. Gain-of-function hot spot mutant p53R248Q regulation of integrin/FAK/ERK signaling in esophageal squamous cell carcinoma. Transl Oncol. 2021;14:100982 pubmed publisher
Constantin D, Widmann C. ASH2L drives proliferation and sensitivity to bleomycin and other genotoxins in Hodgkin's lymphoma and testicular cancer cells. Cell Death Dis. 2020;11:1019 pubmed publisher
Tripathi H, Al Darraji A, Abo Aly M, Peng H, Shokri E, Chelvarajan L, et al. Autotaxin inhibition reduces cardiac inflammation and mitigates adverse cardiac remodeling after myocardial infarction. J Mol Cell Cardiol. 2020;149:95-114 pubmed publisher
Oomen M, Hedger A, Watts J, Dekker J. Detecting chromatin interactions between and along sister chromatids with SisterC. Nat Methods. 2020;17:1002-1009 pubmed publisher
Zhou S, Zhang W, Cai G, Ding Y, Wei C, Li S, et al. Myofiber necroptosis promotes muscle stem cell proliferation via releasing Tenascin-C during regeneration. Cell Res. 2020;30:1063-1077 pubmed publisher
Sullivan C, Brown N, Vasiliauskas J, Pathrose P, Starnes S, Waltz S. Prostate Epithelial RON Signaling Promotes M2 Macrophage Activation to Drive Prostate Tumor Growth and Progression. Mol Cancer Res. 2020;18:1244-1254 pubmed publisher
DiToro D, Harbour S, Bando J, Benavides G, Witte S, Laufer V, et al. Insulin-Like Growth Factors Are Key Regulators of T Helper 17 Regulatory T Cell Balance in Autoimmunity. Immunity. 2020;52:650-667.e10 pubmed publisher
Kretschmer L, Flossdorf M, Mir J, Cho Y, Plambeck M, Treise I, et al. Differential expansion of T central memory precursor and effector subsets is regulated by division speed. Nat Commun. 2020;11:113 pubmed publisher
McAlpine C, Kiss M, Rattik S, He S, Vassalli A, Valet C, et al. Sleep modulates haematopoiesis and protects against atherosclerosis. Nature. 2019;566:383-387 pubmed publisher
Schmidt K, Zhang Q, Tasdogan A, Petzold A, Dahl A, Arneth B, et al. The H3K4 methyltransferase Setd1b is essential for hematopoietic stem and progenitor cell homeostasis in mice. elife. 2018;7: pubmed publisher
Zilio S, Vella J, De La Fuente A, Daftarian P, Weed D, Kaifer A, et al. 4PD Functionalized Dendrimers: A Flexible Tool for In Vivo Gene Silencing of Tumor-Educated Myeloid Cells. J Immunol. 2017;198:4166-4177 pubmed publisher
Li H, Liu P, Xu S, Li Y, Dekker J, Li B, et al. FOXP1 controls mesenchymal stem cell commitment and senescence during skeletal aging. J Clin Invest. 2017;127:1241-1253 pubmed publisher
Youn M, Wang N, LaVasseur C, Bibikova E, Kam S, Glader B, et al. Loss of Forkhead box M1 promotes erythropoiesis through increased proliferation of erythroid progenitors. Haematologica. 2017;102:826-834 pubmed publisher
Danno S, Kubouchi K, Mehruba M, Abe M, Natsume R, Sakimura K, et al. PKN2 is essential for mouse embryonic development and proliferation of mouse fibroblasts. Genes Cells. 2017;22:220-236 pubmed publisher
Liang J, Yan R, Chen G, Feng J, Wu W, Ren W, et al. Downregulation of ZBTB24 hampers the G0/1- to S-phase cell-cycle transition via upregulating the expression of IRF-4 in human B cells. Genes Immun. 2016;17:276-82 pubmed publisher
Hettmer S, Schinzel A, Tchessalova D, Schneider M, Parker C, Bronson R, et al. Functional genomic screening reveals asparagine dependence as a metabolic vulnerability in sarcoma. elife. 2015;4: pubmed publisher
Charlton J, Tsoukatou D, Mamalaki C, Chatzidakis I. Programmed death 1 regulates memory phenotype CD4 T cell accumulation, inhibits expansion of the effector memory phenotype subset and modulates production of effector cytokines. PLoS ONE. 2015;10:e0119200 pubmed publisher
Ohta S, Wood L, Toramoto I, Yagyu K, Fukagawa T, Earnshaw W. CENP-32 is required to maintain centrosomal dominance in bipolar spindle assembly. Mol Biol Cell. 2015;26:1225-37 pubmed publisher
Fong M, Zhou W, Liu L, Alontaga A, Chandra M, Ashby J, et al. Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis. Nat Cell Biol. 2015;17:183-94 pubmed publisher
Cao J, Lu Y, Qi J, An G, Mao Z, Jia H, et al. MiR-630 inhibits proliferation by targeting CDC7 kinase, but maintains the apoptotic balance by targeting multiple modulators in human lung cancer A549 cells. Cell Death Dis. 2014;5:e1426 pubmed publisher
Su N, Shi S, Zhu X, Borazanci A, Shi F, Gan Y. Interleukin-7 expression and its effect on natural killer cells in patients with multiple sclerosis. J Neuroimmunol. 2014;276:180-6 pubmed publisher
Moding E, Lee C, Castle K, Oh P, Mao L, Zha S, et al. Atm deletion with dual recombinase technology preferentially radiosensitizes tumor endothelium. J Clin Invest. 2014;124:3325-38 pubmed publisher
Joedicke J, Dietze K, Zelinskyy G, Dittmer U. The phenotype and activation status of regulatory T cells during Friend retrovirus infection. Virol Sin. 2014;29:48-60 pubmed publisher
Vom Berg J, Vrohlings M, Haller S, Haimovici A, Kulig P, Sledzińska A, et al. Intratumoral IL-12 combined with CTLA-4 blockade elicits T cell-mediated glioma rejection. J Exp Med. 2013;210:2803-11 pubmed publisher
Dirice E, Kahraman S, Jiang W, El Ouaamari A, De Jesus D, Teo A, et al. Soluble factors secreted by T cells promote ?-cell proliferation. Diabetes. 2014;63:188-202 pubmed publisher
Kullmann M, Grubbauer C, Goetsch K, Jakel H, Podmirseg S, Trockenbacher A, et al. The p27-Skp2 axis mediates glucocorticoid-induced cell cycle arrest in T-lymphoma cells. Cell Cycle. 2013;12:2625-35 pubmed publisher
Zhang Y, Jones M, McCabe A, Winslow G, Avram D, MacNamara K. MyD88 signaling in CD4 T cells promotes IFN-? production and hematopoietic progenitor cell expansion in response to intracellular bacterial infection. J Immunol. 2013;190:4725-35 pubmed publisher
Wong E, Khan T, Mohan C, Rahman Z. The lupus-prone NZM2410/NZW strain-derived Sle1b sublocus alters the germinal center checkpoint in female mice in a B cell-intrinsic manner. J Immunol. 2012;189:5667-81 pubmed publisher
Ren M, Qin H, Ren R, Cowell J. Ponatinib suppresses the development of myeloid and lymphoid malignancies associated with FGFR1 abnormalities. Leukemia. 2013;27:32-40 pubmed publisher
Chow K, Qiu J, Lee J, Hsu S, Yang S, Wu N, et al. Selective reduction of post-selection CD8 thymocyte proliferation in IL-15R? deficient mice. PLoS ONE. 2012;7:e33152 pubmed publisher
Xue X, Taylor M, Anderson E, Hao C, Qu A, Greenson J, et al. Hypoxia-inducible factor-2α activation promotes colorectal cancer progression by dysregulating iron homeostasis. Cancer Res. 2012;72:2285-93 pubmed publisher
Zhou Y, He Y, Chen C, Ji J, Niu J, Wang H, et al. Time-specific blockade of PDGFR with Imatinib (Glivec®) causes cataract and disruption of lens fiber cells in neonatal mice. Virchows Arch. 2011;458:349-56 pubmed publisher
Han J, SHEN W, Jiang Y, Yu B, He Y, Li N, et al. Distribution, development and proliferation of interstitial cells of Cajal in murine colon: an immunohistochemical study from neonatal to adult life. Histochem Cell Biol. 2010;133:163-75 pubmed publisher
Mei F, Zhu J, Guo S, Zhou D, Han J, Yu B, et al. An age-dependent proliferation is involved in the postnatal development of interstitial cells of Cajal in the small intestine of mice. Histochem Cell Biol. 2009;131:43-53 pubmed publisher
product information
Product Type :
Antibody
Product Name :
BrdU Monoclonal Antibody (BU20A), APC, eBioscience
Catalog # :
17-5071-41
Quantity :
25 Tests
Price :
US 164.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Chemical
Applications :
Flow Cytometry: 5 uL (0.125 ug)/test
Species :
Chemical
Clone :
BU20A
Isotype :
IgG1, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
Bromodeoxyuridine (5-bromo-2-deoxyuridine, BrdU) is a synthetic nucleoside that is an analogue of thymidine. BrdU is commonly used in the detection of proliferating cells in living tissues, and can be incorporated into the newly synthesized DNA of replicating cells (during the S phase of the cell cycle), substituting for thymidine during DNA replication. Antibodies specific for BrdU can then be used to detect the incorporated chemical, thus indicating cells that were actively replicating their DNA. Binding of the antibody requires denaturation of the DNA, usually by exposing the cells to acid or heat.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 5 uL (0.125 ug)/test
Aliases :
5-Bromo-2-deoxyuridine; Bromodeoxyuridine
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA