PIR-A/B Monoclonal Antibody (10-1-PIR), APC, eBioscience | Invitrogen 17-3101-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PIR-A/B Monoclonal Antibody (10-1-PIR), APC, eBioscience

catalog :

17-3101-82

quantity :

100 ug

price :

US 372.00

clonality :

monoclonal

host :

rat

conjugate :

APC

clone name :

10-1-PIR

reactivity :

mouse

application :

flow cytometry

citations: 2

Reference
Moretti F, Klapproth S, Ruppert R, Margraf A, Weber J, Pick R, et al. Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus. elife. 2018;7: pubmed publisher
Torii I, Oka S, Hotomi M, Benjamin W, Takai T, Kearney J, et al. PIR-B-deficient mice are susceptible to Salmonella infection. J Immunol. 2008;181:4229-39 pubmed

product information

Product Type :

Antibody

Product Name :

PIR-A/B Monoclonal Antibody (10-1-PIR), APC, eBioscience

Catalog # :

17-3101-82

Quantity :

100 ug

Price :

US 372.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.25 ug/test

Species :

Mouse

Clone :

10-1-PIR

Isotype :

IgG2b, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

Paired Ig-like receptors of activating (PIR)-A and -B are expressed on B lymphocytes, macrophages, dendritic cells, platelets, granulocytes, and mast cells, but not on T cells, NK cells, and erythrocytes. These cell surface glycoproteins contain six extracellular Ig-like domains with distinct cytoplasmic and transmembrane regions. The PIR-A receptor activates through signaling molecules containing immunoreceptor tyrosine-based activation motifs. In contrast, the PIR-B receptor inhibits through proteins possessing immunoreceptor tyrosine-based inhibitory motifs. PIRs bind MHC class I to modulate immune system homeostasis and cell signaling.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 ug/test

Aliases :

6M21; CD85k; cell-surface glycoprotein p91; Gp49b; Gp91; leukocyte immunoglobulin-like receptor 3; leukocyte immunoglobulin-like receptor subfamily B member 3; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3; Lilrb3; Lilrb4; LIR-3; Ly89; paired Ig-like receptor B; paired immunoglobulin-like receptor; paired immunoglobulin-like receptor B; paired-Ig-like receptor A1; Pir; Pira1; PIR-A1; Pirb; PIR-B