This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD226 (DNAM-1) Monoclonal Antibody (10E5), APC, eBioscience
catalog :
17-2261-82
quantity :
100 ug
price :
US 407.00
clonality :
monoclonal
host :
rat
conjugate :
APC
clone name :
1.00E+06

The same clone is also sold as:
reactivity :
mouse
application :
flow cytometry
citations: 11
Reference
Ma J, Hu W, Zhang D, Xie J, Duan C, Liu Y, et al. CD226 knockout alleviates high-fat diet induced obesity by suppressing proinflammatory macrophage phenotype. J Transl Med. 2021;19:477 pubmed publisher
Li Z, Morman R, Hegermiller E, Sun M, Bartom E, Maienschein Cline M, et al. The transcriptional repressor ID2 supports natural killer cell maturation by controlling TCF1 amplitude. J Exp Med. 2021;218: pubmed publisher
Goh W, Scheer S, Jackson J, Hediyeh Zadeh S, Delconte R, Schuster I, et al. Hhex Directly Represses BIM-Dependent Apoptosis to Promote NK Cell Development and Maintenance. Cell Rep. 2020;33:108285 pubmed publisher
Zhang X, Feng J, Chen S, Yang H, Dong Z. Synergized regulation of NK cell education by NKG2A and specific Ly49 family members. Nat Commun. 2019;10:5010 pubmed publisher
Tang M, Khan M, Croxford J, Tan K, Angeli V, Gasser S. The DNA damage response induces antigen presenting cell-like functions in fibroblasts. Eur J Immunol. 2014;44:1108-18 pubmed publisher
Mizutani T, Neugebauer N, Putz E, Moritz N, Simma O, Zebedin Brandl E, et al. Conditional IFNAR1 ablation reveals distinct requirements of Type I IFN signaling for NK cell maturation and tumor surveillance. Oncoimmunology. 2012;1:1027-1037 pubmed
Zhu J, Huang X, Yang Y. NKG2D is required for NK cell activation and function in response to E1-deleted adenovirus. J Immunol. 2010;185:7480-6 pubmed publisher
Brady J, Carotta S, Thong R, Chan C, Hayakawa Y, Smyth M, et al. The interactions of multiple cytokines control NK cell maturation. J Immunol. 2010;185:6679-88 pubmed publisher
Fang L, Zhang X, Miao J, Zhao F, Yang K, Zhuang R, et al. Expression of CD226 antagonizes apoptotic cell death in murine thymocytes. J Immunol. 2009;182:5453-60 pubmed publisher
Dardalhon V, Schubart A, Reddy J, Meyers J, Monney L, Sabatos C, et al. CD226 is specifically expressed on the surface of Th1 cells and regulates their expansion and effector functions. J Immunol. 2005;175:1558-65 pubmed
Tahara Hanaoka S, Miyamoto A, Hara A, Honda S, Shibuya K, Shibuya A. Identification and characterization of murine DNAM-1 (CD226) and its poliovirus receptor family ligands. Biochem Biophys Res Commun. 2005;329:996-1000 pubmed
product information
Product Type :
Antibody
Product Name :
CD226 (DNAM-1) Monoclonal Antibody (10E5), APC, eBioscience
Catalog # :
17-2261-82
Quantity :
100 ug
Price :
US 407.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.25 ug/test
Species :
Mouse
Clone :
1.00E+06
Isotype :
IgG2b, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
DNAM 1 is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.25 ug/test
Aliases :
adhesion glycoprotein; BC051526; Cd226; CD226 antigen; CD226 molecule; DNAM 1; DNAM1; DNAM-1; DNAX accessory molecule 1; DNAX accessory molecule-1; platelet and T cell activation antigen 1; platelet and T-cell activation antigen 1; Pta1; T lineage-specific activation antigen 1 antigen; TLiSA1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA