| Reference |
|---|
Chen F, Chen Z, Wu H, Chen X, Zhan P, Wei Z, et al. Mesenchymal Stem Cell-Derived Exosomes Attenuate Murine Cytomegalovirus-Infected Pneumonia via NF-κB/NLRP3 Signaling Pathway. Viruses. 2024;16: pubmed publisher |
Sui H, Deng W, Chai Q, Han B, Zhang Y, Wei Z, et al. YTE-17 inhibits colonic carcinogenesis by resetting antitumor immune response via Wnt5a/JNK mediated metabolic signaling. J Pharm Anal. 2024;14:100901 pubmed publisher |
Ma J, Tan J, Zhang W, Bai M, Liu K. Prenatal inflammation exposure accelerates lung cancer tumorigenesis in offspring mouse: possible links to IRE1α/XBP1-mediated M2-like polarization of TAMs and PD-L1 up-expression. Cancer Immunol Immunother. 2024;73:88 pubmed publisher |
Wu S, Tang W, Liu L, Wei K, Tang Y, Ma J, et al. Obesity-induced downregulation of miR-192 exacerbates lipopolysaccharide-induced acute lung injury by promoting macrophage activation. Cell Mol Biol Lett. 2024;29:36 pubmed publisher |
Li X, Li S, Fu X, Wang Y. Apoptotic extracellular vesicles restore homeostasis of the articular microenvironment for the treatment of rheumatoid arthritis. Bioact Mater. 2024;35:564-576 pubmed publisher |
Liu C, Guo S, Liu R, Guo M, Wang Q, Chai Z, et al. Fasudil-modified macrophages reduce inflammation and regulate the immune response in experimental autoimmune encephalomyelitis. Neural Regen Res. 2024;19:671-679 pubmed publisher |
Provera A, Ramavath N, Gadipudi L, Gigliotti C, Boggio E, Vecchio C, et al. Role of the co-stimulatory molecule inducible T-cell co-stimulator ligand (ICOSL) in the progression of experimental metabolic dysfunction-associated steatohepatitis. Front Immunol. 2023;14:1290391 pubmed publisher |
Liu Y, Zhan Z, Kang Z, Li M, Lv Y, Li S, et al. Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma. Acta Pharm Sin B. 2023;13:4748-4764 pubmed publisher |
Alexander E, Fahey E, Phanstiel O, Gilmour S. Loss of Anti-Tumor Efficacy by Polyamine Blocking Therapy in GCN2 Null Mice. Biomedicines. 2023;11: pubmed publisher |
Cao X, Xu Y, Zhou C, Huo J, Su S, Liu L, et al. Oral Immunotherapy Reshapes Intestinal Immunosuppression via Metabolic Reprogramming to Enhance Systemic Anti-Tumor Immunity. Adv Sci (Weinh). 2023;10:e2302910 pubmed publisher |
He J, Wei L, Tan S, Liang B, Liu J, Lu L, et al. Macrophage RAGE deficiency prevents myocardial fibrosis by repressing autophagy-mediated macrophage alternative activation. FASEB J. 2023;37:e23259 pubmed publisher |
Bryan A, Pingali P, Joslyn M, Li H, Bernas T, Koblinski J, et al. High-Dose Acetaminophen with N-acetylcysteine Rescue Inhibits M2 Polarization of Tumor-Associated Macrophages. Cancers (Basel). 2023;15: pubmed publisher |
Luo J, Ren H, Chen M, Zhao Q, Yang N, Liu Q, et al. Hydrochlorothiazide-induced glucose metabolism disorder is mediated by the gut microbiota via LPS-TLR4-related macrophage polarization. iScience. 2023;26:107130 pubmed publisher |
Zhu D, Huang M, Shen P, Zhang B, Chen G, Chen J, et al. TREM2 expression promotes liver and peritoneal M2 macrophage polarization in mice infected with Schistosoma japonicum. J Cell Mol Med. 2023;27:2261-2269 pubmed publisher |
Liu W, Chen W, Xie M, Chen C, Shao Z, Zhang Y, et al. Traumatic brain injury stimulates sympathetic tone-mediated bone marrow myelopoiesis to favor fracture healing. Signal Transduct Target Ther. 2023;8:260 pubmed publisher |
Li P, Ji X, Shan M, Wang Y, Dai X, Yin M, et al. Melatonin regulates microglial polarization to M2 cell via RhoA/ROCK signaling pathway in epilepsy. Immun Inflamm Dis. 2023;11:e900 pubmed publisher |
Huang Y, Cui D, Chen L, Tong H, Wu H, Muller G, et al. A pref-1-controlled non-inflammatory mechanism of insulin resistance. iScience. 2023;26:106923 pubmed publisher |
Wen S, Li F, Tang Y, Dong L, He Y, Deng Y, et al. MIR222HG attenuates macrophage M2 polarization and allergic inflammation in allergic rhinitis by targeting the miR146a-5p/TRAF6/NF-κB axis. Front Immunol. 2023;14:1168920 pubmed publisher |
Zuo B, Li T, Liu X, Wang S, Cheng J, Liu X, et al. Dipeptidyl peptidase 4 inhibitor reduces tumor-associated macrophages and enhances anti-PD-L1-mediated tumor suppression in non-small cell lung cancer. Clin Transl Oncol. 2023;25:3188-3202 pubmed publisher |
Feng L, Luo G, Li Y, Zhang C, Liu Y, Liu Y, et al. Curcumin-dependent phenotypic transformation of microglia mediates resistance to pseudorabies-induced encephalitis. Vet Res. 2023;54:25 pubmed publisher |
Huang J, Leng X, Jiang T, Xu L, Zheng J, Fang M, et al. Oxygen-carrying nanoplatform to reprogram tumor immunosuppressive microenvironment and enhance photothermal-immunotherapy. Mater Today Bio. 2023;19:100555 pubmed publisher |
Yang N, Shi N, Yao Z, Liu H, Guo W. Gallium-modified gelatin nanoparticles loaded with quercetin promote skin wound healing via the regulation of bacterial proliferation and macrophage polarization. Front Bioeng Biotechnol. 2023;11:1124944 pubmed publisher |
Wang J, Xue Y, Wang Y, Liu C, Hu S, Zhao H, et al. BMP-2 functional polypeptides relieve osteolysis via bi-regulating bone formation and resorption coupled with macrophage polarization. NPJ Regen Med. 2023;8:6 pubmed publisher |
Yang Y, Ni M, Zong R, Yu M, Sun Y, Li J, et al. Targeting Notch1-YAP Circuit Reprograms Macrophage Polarization and Alleviates Acute Liver Injury in Mice. Cell Mol Gastroenterol Hepatol. 2023;15:1085-1104 pubmed publisher |
Li S, Zhang L, Liu C, Kim J, Su K, Chen T, et al. Spontaneous immunomodulation and regulation of angiogenesis and osteogenesis by Sr/Cu-borosilicate glass (BSG) bone cement to repair critical bone defects. Bioact Mater. 2023;23:101-117 pubmed publisher |
Palacios L, Peyret V, Viano M, Geysels R, Chocobar Y, Volpini X, et al. TIM3 Expression in Anaplastic-Thyroid-Cancer-Infiltrating Macrophages: An Emerging Immunotherapeutic Target. Biology (Basel). 2022;11: pubmed publisher |
Zhang X, Chen C, Ling C, Luo S, Xiong Z, Liu X, et al. EGFR tyrosine kinase activity and Rab GTPases coordinate EGFR trafficking to regulate macrophage activation in sepsis. Cell Death Dis. 2022;13:934 pubmed publisher |
Jiang F, Xia M, Zhang Y, Chang J, Cao J, Zhang Z, et al. Cannabinoid receptor-2 attenuates neuroinflammation by promoting autophagy-mediated degradation of the NLRP3 inflammasome post spinal cord injury. Front Immunol. 2022;13:993168 pubmed publisher |
Howard Z, Gomatam C, Rabolli C, Lowe J, Piepho A, Bansal S, et al. Mineralocorticoid receptor antagonists and glucocorticoids differentially affect skeletal muscle inflammation and pathology in muscular dystrophy. JCI Insight. 2022;7: pubmed publisher |
Liu X, Jiang Q, Shen S, Hou Y. Local and systemic inflammation triggers different outcomes of tumor growth related to infiltration of anti-tumor or pro-tumor macrophages. Chin Med J (Engl). 2022;135:1821-1828 pubmed publisher |
Li Y, Li G, Zhang L, Li Y, Zhao Z. G9a promotes inflammation in Streptococcus pneumoniae induced pneumonia mice by stimulating M1 macrophage polarization and H3K9me2 methylation in FOXP1 promoter region. Ann Transl Med. 2022;10:583 pubmed publisher |
Zhu Q, Zai H, Zhang K, Zhang X, Luo N, Li X, et al. L-norvaline affects the proliferation of breast cancer cells based on the microbiome and metabolome analysis. J Appl Microbiol. 2022;133:1014-1026 pubmed publisher |
Wen Z, Lin S, Li C, Ouyang Z, Chen Z, Li S, et al. MiR-92a/KLF4/p110δ regulates titanium particles-induced macrophages inflammation and osteolysis. Cell Death Discov. 2022;8:197 pubmed publisher |
Qian Z, Chen H, Xia M, Chang J, Li X, Ye S, et al. Activation of glucagon-like peptide-1 receptor in microglia attenuates neuroinflammation-induced glial scarring via rescuing Arf and Rho GAP adapter protein 3 expressions after nerve injury. Int J Biol Sci. 2022;18:1328-1346 pubmed publisher |
Li K, Yan G, Huang H, Zheng M, Ma K, Cui X, et al. Anti-inflammatory and immunomodulatory effects of the extracellular vesicles derived from human umbilical cord mesenchymal stem cells on osteoarthritis via M2 macrophages. J Nanobiotechnology. 2022;20:38 pubmed publisher |
Wu Q, Huang Q, Jiang Y, Sun F, Liang B, Wang J, et al. Remodeling Chondroitin-6-Sulfate-Mediated Immune Exclusion Enhances Anti-PD-1 Response in Colorectal Cancer with Microsatellite Stability. Cancer Immunol Res. 2022;10:182-199 pubmed publisher |
Liu J, Zhang Y, Sheng H, Liang C, Liu H, Moran Guerrero J, et al. Hyperoside Suppresses Renal Inflammation by Regulating Macrophage Polarization in Mice With Type 2 Diabetes Mellitus. Front Immunol. 2021;12:733808 pubmed publisher |
Jiang Q, Bai G, Liu X, Chen Y, Xu G, Yang C, et al. 3D GelMA ICC Scaffolds Combined with SW033291 for Bone Regeneration by Modulating Macrophage Polarization. Pharmaceutics. 2021;13: pubmed publisher |
Jhan M, Chen C, Shen T, Tseng P, Wang Y, Satria R, et al. Polarization of Type 1 Macrophages Is Associated with the Severity of Viral Encephalitis Caused by Japanese Encephalitis Virus and Dengue Virus. Cells. 2021;10: pubmed publisher |
Nascimento Da Conceicao V, Sun Y, Ramachandran K, Chauhan A, Raveendran A, Venkatesan M, et al. Resolving macrophage polarization through distinct Ca2+ entry channel that maintains intracellular signaling and mitochondrial bioenergetics. iScience. 2021;24:103339 pubmed publisher |
Liu X, Xu Y, Li Y, Pan Y, Zhao S, Hou Y. Ferumoxytol-β-glucan Inhibits Melanoma Growth via Interacting with Dectin-1 to Polarize Macrophages into M1 Phenotype. Int J Med Sci. 2021;18:3125-3139 pubmed publisher |
Han H, Peng G, Meister M, Yao H, Yang J, Zou M, et al. Electronic Cigarette Exposure Enhances Lung Inflammatory and Fibrotic Responses in COPD Mice. Front Pharmacol. 2021;12:726586 pubmed publisher |
Fu Y, Peng Y, Zhao S, Mou J, Zeng L, Jiang X, et al. Combination Foretinib and Anti-PD-1 Antibody Immunotherapy for Colorectal Carcinoma. Front Cell Dev Biol. 2021;9:689727 pubmed publisher |
Su L, Dong Y, Wang Y, Wang Y, Guan B, Lu Y, et al. Potential role of senescent macrophages in radiation-induced pulmonary fibrosis. Cell Death Dis. 2021;12:527 pubmed publisher |
Wang F, Kong L, Wang W, Shi L, Wang M, Chai Y, et al. Adrenomedullin 2 improves bone regeneration in type 1 diabetic rats by restoring imbalanced macrophage polarization and impaired osteogenesis. Stem Cell Res Ther. 2021;12:288 pubmed publisher |
Kong F, Sun K, Zhu J, Li F, Lin F, Sun X, et al. PD-L1 Improves Motor Function and Alleviates Neuropathic Pain in Male Mice After Spinal Cord Injury by Inhibiting MAPK Pathway. Front Immunol. 2021;12:670646 pubmed publisher |
Wang J, Chen Q, Zhang Z, Wang S, Wang Y, Xiang M, et al. Azithromycin alleviates systemic lupus erythematosus via the promotion of M2 polarisation in lupus mice. Cell Death Discov. 2021;7:82 pubmed publisher |
Dong B, Wang C, Zhang J, Zhang J, Gu Y, Guo X, et al. Exosomes from human umbilical cord mesenchymal stem cells attenuate the inflammation of severe steroid-resistant asthma by reshaping macrophage polarization. Stem Cell Res Ther. 2021;12:204 pubmed publisher |
Song L, Chang R, Sun X, Lu L, Gao H, Lu H, et al. Macrophage-derived EDA-A2 inhibits intestinal stem cells by targeting miR-494/EDA2R/β-catenin signaling in mice. Commun Biol. 2021;4:213 pubmed publisher |
Vonderhaar E, Barnekow N, McAllister D, McOlash L, Eid M, Riese M, et al. STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer. Cell Mol Gastroenterol Hepatol. 2021;12:41-58 pubmed publisher |
Wang Y, Han B, Wang Y, Wang C, Zhang H, Xue J, et al. Mesenchymal stem cell-secreted extracellular vesicles carrying TGF-β1 up-regulate miR-132 and promote mouse M2 macrophage polarization. J Cell Mol Med. 2020;24:12750-12764 pubmed publisher |
Doty D, Schueler J, Mott V, Bryan C, Moore N, Ho J, et al. Modeling Immune Checkpoint Inhibitor Efficacy in Syngeneic Mouse Tumors in an Ex Vivo Immuno-Oncology Dynamic Environment. Int J Mol Sci. 2020;21: pubmed publisher |
Chen J, Wang L, Xu H, Xing L, Zhuang Z, Zheng Y, et al. Meningeal lymphatics clear erythrocytes that arise from subarachnoid hemorrhage. Nat Commun. 2020;11:3159 pubmed publisher |
Lee Y, Song S, Hong H, Oh B, Lee W, Cho Y. The FBW7-MCL-1 axis is key in M1 and M2 macrophage-related colon cancer cell progression: validating the immunotherapeutic value of targeting PI3Kγ. Exp Mol Med. 2020;52:815-831 pubmed publisher |
Qiu J, Peng P, Xin M, Wen Z, Chen Z, Lin S, et al. ZBTB20-mediated titanium particle-induced peri-implant osteolysis by promoting macrophage inflammatory responses. Biomater Sci. 2020;8:3147-3163 pubmed publisher |
Zhang N, Shou B, Chen L, Lai X, Luo Y, Meng X, et al. Cardioprotective Effects of Latifolin Against Doxorubicin-Induced Cardiotoxicity by Macrophage Polarization in Mice. J Cardiovasc Pharmacol. 2020;75:564-572 pubmed publisher |
Kong F, Zhao S, Sun P, Liu H, Jie J, Xu T, et al. Macrophage MSR1 promotes the formation of foamy macrophage and neuronal apoptosis after spinal cord injury. J Neuroinflammation. 2020;17:62 pubmed publisher |
Jin S, Meng C, He Y, Wang X, Zhang Q, Wang Z, et al. Curcumin prevents osteocyte apoptosis by inhibiting M1-type macrophage polarization in mice model of glucocorticoid-associated osteonecrosis of the femoral head. J Orthop Res. 2020;38:2020-2030 pubmed publisher |
Zhao S, Kong F, Jie J, Li Q, Liu H, Xu A, et al. Macrophage MSR1 promotes BMSC osteogenic differentiation and M2-like polarization by activating PI3K/AKT/GSK3β/β-catenin pathway. Theranostics. 2020;10:17-35 pubmed publisher |
Fang D, Tang Q, Kong Y, Wang Q, Gu J, Fang X, et al. MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment. J Immunother Cancer. 2019;7:327 pubmed publisher |
Zhang Y, Li S, Liu Q, Long R, Feng J, Qin H, et al. Mycobacterium tuberculosis Heat-Shock Protein 16.3 Induces Macrophage M2 Polarization Through CCRL2/CX3CR1. Inflammation. 2020;43:487-506 pubmed publisher |
Peng J, Wang K, Xiang W, Li Y, Hao Y, Guan Y. Rosiglitazone polarizes microglia and protects against pilocarpine-induced status epilepticus. CNS Neurosci Ther. 2019;25:1363-1372 pubmed publisher |
Mau T, O Brien M, Ghosh A, Miller R, Yung R. Life-span Extension Drug Interventions Affect Adipose Tissue Inflammation in Aging. J Gerontol A Biol Sci Med Sci. 2020;75:89-98 pubmed publisher |
Kim T, Park J, Kim D, Gautam A, Akauliya M, Kim J, et al. Anti-Bacterial Effect of CpG-DNA Involves Enhancement of the Complement Systems. Int J Mol Sci. 2019;20: pubmed publisher |
Wiktorowicz J, Chowdhury I, Stafford S, Choudhuri S, Dey N, Garg N. Integrated Functional Analysis of the Nuclear Proteome of Classically and Alternatively Activated Macrophages. Mediators Inflamm. 2019;2019:3481430 pubmed publisher |
Guo M, Xiao J, Sheng X, Zhang X, Tie Y, Wang L, et al. Ginsenoside Rg3 Mitigates Atherosclerosis Progression in Diabetic apoE-/- Mice by Skewing Macrophages to the M2 Phenotype. Front Pharmacol. 2018;9:464 pubmed publisher |
Yin X, Feng L, Ma D, Yin P, Wang X, Hou S, et al. Roles of astrocytic connexin-43, hemichannels, and gap junctions in oxygen-glucose deprivation/reperfusion injury induced neuroinflammation and the possible regulatory mechanisms of salvianolic acid B and carbenoxolone. J Neuroinflammation. 2018;15:97 pubmed publisher |
Gao S, Li C, Zhu Y, Wang Y, Sui A, Zhong Y, et al. PEDF mediates pathological neovascularization by regulating macrophage recruitment and polarization in the mouse model of oxygen-induced retinopathy. Sci Rep. 2017;7:42846 pubmed publisher |
