CD201 (EPCR) Monoclonal Antibody (RCR-227), APC, eBioscience | Invitrogen 17-2018-42 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD201 (EPCR) Monoclonal Antibody (RCR-227), APC, eBioscience

catalog :

17-2018-42

quantity :

100 Tests

price :

US 366.00

clonality :

monoclonal

host :

rat

conjugate :

APC

clone name :

RCR-227

reactivity :

human

application :

flow cytometry

citations: 10

Reference
Zhang P, He Q, Wang Y, Zhou G, Chen Y, Tang L, et al. Protein C receptor maintains cancer stem cell properties via activating lipid synthesis in nasopharyngeal carcinoma. Signal Transduct Target Ther. 2022;7:46 pubmed publisher
Wu T, Wang Y, Xiao T, Ai Y, Li J, Zeng Y, et al. Lentiviral CRISPR-guided RNA library screening identified Adam17 as an upstream negative regulator of Procr in mammary epithelium. BMC Biotechnol. 2021;21:42 pubmed publisher
Wang D, Hu X, Liu C, Jia Y, Bai Y, Cai C, et al. Protein C receptor is a therapeutic stem cell target in a distinct group of breast cancers. Cell Res. 2019;29:832-845 pubmed publisher
Wang D, Liu C, Wang J, Jia Y, Hu X, Jiang H, et al. Protein C receptor stimulates multiple signaling pathways in breast cancer cells. J Biol Chem. 2018;293:1413-1424 pubmed publisher
Lin C, Sharma S, Farrugia M, McLaughlin S, Ice R, Loskutov Y, et al. Kruppel-like factor 4 signals through microRNA-206 to promote tumor initiation and cell survival. Oncogenesis. 2015;4:e155 pubmed publisher
Guitton C, Gerard N, Quillard T, Charreau B. Circulating endothelial cell protein C receptor: endothelial regulation and cumulative impact of gender and A3 haplotype. J Vasc Res. 2011;48:336-46 pubmed publisher
Crawley J. Multiple roles of the endothelial cell protein C receptor. J Thromb Haemost. 2007;5:1813-6 pubmed
Villegas Mendez A, Montes R, Ambrose L, Warrens A, Laffan M, Lane D. Proteolysis of the endothelial cell protein C receptor by neutrophil proteinase 3. J Thromb Haemost. 2007;5:980-8 pubmed
Stephenson D, Toltl L, Beaudin S, Liaw P. Modulation of monocyte function by activated protein C, a natural anticoagulant. J Immunol. 2006;177:2115-22 pubmed
Feistritzer C, Mosheimer B, Sturn D, Riewald M, Patsch J, Wiedermann C. Endothelial protein C receptor-dependent inhibition of migration of human lymphocytes by protein C involves epidermal growth factor receptor. J Immunol. 2006;176:1019-25 pubmed

product information

Product Type :

Antibody

Product Name :

CD201 (EPCR) Monoclonal Antibody (RCR-227), APC, eBioscience

Catalog # :

17-2018-42

Quantity :

100 Tests

Price :

US 366.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (0.125 ug)/test

Species :

Human

Clone :

RCR-227

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (0.125 ug)/test

Aliases :

Activated protein C receptor; AI325044; APC receptor; bA42O4.2; CCCA; CCD41; CD antigen CD201; CD201; CD201 antigen; cell cycle, centrosome-associated protein; centrocyclin; Centrosomal protein CCD41; endothelial cell protein C receptor; Endothelial protein C receptor; Epcr; PROCR; protein C receptor; protein C receptor, endothelial