CD193 (CCR3) Monoclonal Antibody (eBio5E8-G9-B4 (5E8-G9-B4)), APC, eBioscience | Invitrogen 17-1939-42 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD193 (CCR3) Monoclonal Antibody (eBio5E8-G9-B4 (5E8-G9-B4)), APC, eBioscience

catalog :

17-1939-42

quantity :

100 Tests

price :

US 364

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

eBio5E8-G9-B4 (5E8-G9-B4)

reactivity :

human

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig s21	Uhlen M, Karlsson M, Zhong W, Tebani A, Pou C, Mikes J, et al. A genome-wide transcriptomic analysis of protein-coding genes in human blood cells. Science. 2019;366: pubmed publisher
	Fekete N, Rojewski M, Furst D, Kreja L, Ignatius A, Dausend J, et al. GMP-compliant isolation and large-scale expansion of bone marrow-derived MSC. PLoS ONE. 2012;7:e43255 pubmed publisher
	Amundsen E, Urdal P, Hagve T, Holthe M, Henriksson C. Absolute neutrophil counts from automated hematology instruments are accurate and precise even at very low levels. Am J Clin Pathol. 2012;137:862-9 pubmed publisher
	Beamer C, Shepherd D. Inhibition of TLR ligand- and interferon gamma-induced murine microglial activation by Panax notoginseng. J Neuroimmune Pharmacol. 2012;7:465-76 pubmed publisher
	Choi H, Kim J, Kwon E, Che J, Lee J, Cho S, et al. Establishment of efficacy and safety assessment of human adipose tissue-derived mesenchymal stem cells (hATMSCs) in a nude rat femoral segmental defect model. J Korean Med Sci. 2011;26:482-91 pubmed publisher
	Sallusto F, Mackay C, Lanzavecchia A. Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells. Science. 1997;277:2005-7 pubmed
	Forssmann U, Uguccioni M, Loetscher P, Dahinden C, Langen H, Thelen M, et al. Eotaxin-2, a novel CC chemokine that is selective for the chemokine receptor CCR3, and acts like eotaxin on human eosinophil and basophil leukocytes. J Exp Med. 1997;185:2171-6 pubmed
	Heath H, Qin S, Rao P, Wu L, LaRosa G, Kassam N, et al. Chemokine receptor usage by human eosinophils. The importance of CCR3 demonstrated using an antagonistic monoclonal antibody. J Clin Invest. 1997;99:178-84 pubmed
	Choe H, Farzan M, Sun Y, Sullivan N, Rollins B, Ponath P, et al. The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell. 1996;85:1135-48 pubmed

product information

Product Type :

Antibody

Product Name :

CD193 (CCR3) Monoclonal Antibody (eBio5E8-G9-B4 (5E8-G9-B4)), APC, eBioscience

Catalog # :

17-1939-42

Quantity :

100 Tests

Price :

US 364

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 µL (0.25 µg)/test

Species :

Human

Clone :

eBio5E8-G9-B4 (5E8-G9-B4)

Isotype :

IgG2b, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

CCR3 (C-C chemokine receptor type 3) binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1 delta. CCR3 trasnduces a signal by increasing the intracellular calcium ions level. It also serves as an alternative co-receptor with CD4 for HIV-1 infection. Other chemokines play important roles in inflammation and are critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 µL (0.25 µg)/test

Aliases :

b-chemokine receptor; CC chemokine receptor 3; C-C chemokine receptor type 3; C-C CKR-3; C-C motif chemokine receptor 3; CC-CKR3; CC-CKR-3; Ccr3; CCR-3; CD193; chemokine (C-C motif) receptor 3; chemokine (C-C) receptor 1,-like 2; chemokine (C-C) receptor 3; CKR3; Cmkbr1l2; CMKBR3; eosinophil CC chemokine receptor 3; eosinophil eotaxin receptor; Macrophage inflammatory protein 1-alpha receptor-like 2; MGC102841; MIP-1 alpha RL2; MIP-1 alphaRL2; probable C-C chemokine receptor type 3

more info or order :

Invitrogen product webpage