CD162 (PSGL-1) Monoclonal Antibody (FLEG), APC, eBioscience | Invitrogen 17-1629-42 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD162 (PSGL-1) Monoclonal Antibody (FLEG), APC, eBioscience

catalog :

17-1629-42

quantity :

100 Tests

price :

US 423

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

FLEG

reactivity :

human

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 2b	Rathod K, Kapil V, Velmurugan S, Khambata R, Siddique U, Khan S, et al. Accelerated resolution of inflammation underlies sex differences in inflammatory responses in humans. J Clin Invest. 2017;127:169-182 pubmed publisher
	Starzonek S, Maar H, Labitzky V, Wicklein D, Rossdam C, Buettner F, et al. Systematic analysis of the human tumor cell binding to human vs. murine E- and P-selectin under static vs. dynamic conditions. Glycobiology. 2020;30:695-709 pubmed publisher
	Park H, Kim D, Choi J, Kim W, Kim J, Senejani A, et al. PPAR? negatively regulates T cell activation to prevent follicular helper T cells and germinal center formation. PLoS ONE. 2014;9:e99127 pubmed publisher
	Nishimura Y, Shimojima M, Tano Y, Miyamura T, Wakita T, Shimizu H. Human P-selectin glycoprotein ligand-1 is a functional receptor for enterovirus 71. Nat Med. 2009;15:794-7 pubmed publisher
	Davenpeck K, Brummet M, Hudson S, Mayer R, Bochner B. Activation of human leukocytes reduces surface P-selectin glycoprotein ligand-1 (PSGL-1, CD162) and adhesion to P-selectin in vitro. J Immunol. 2000;165:2764-72 pubmed
	Levesque J, Zannettino A, Pudney M, Niutta S, Haylock D, Snapp K, et al. PSGL-1-mediated adhesion of human hematopoietic progenitors to P-selectin results in suppression of hematopoiesis. Immunity. 1999;11:369-78 pubmed

product information

Product Type :

Antibody

Product Name :

CD162 (PSGL-1) Monoclonal Antibody (FLEG), APC, eBioscience

Catalog # :

17-1629-42

Quantity :

100 Tests

Price :

US 423

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 µL (0.125 µg)/test

Species :

Human

Clone :

FLEG

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

CD162 (PSGL-1) is a 120 kDa homodimer protein found on the surface of leukocytes and platelets. CD162 is known to bind CD62P (P-selectin), CD62L (L-selectin), and to a lower degree CD62E (E-selectin). These interactions play a critical role in leukocyte adhesion, rolling and extravasation. CD162 has been shown to be an important immune marker of T cell exhaustion in chronic viral infections and cancer.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 µL (0.125 µg)/test

Aliases :

CD162; CLA; Cutaneous lymphocyte associated antigen; cutaneous lymphocyte-associated associated antigen; leukocyte cell surface adhesion molecule; P-selectin glycoprotein ligand 1; P-selectin glycoprotein ligand 1 propeptide; P-selectin glycoprotein ligand-1; Psgl1; Psgl-1; Selectin P ligand; selectin, platelet (p-selectin) ligand; Selp1; SELPG; Selpl; SELPLG

more info or order :

Invitrogen product webpage