CD150 Monoclonal Antibody (mShad150), APC, eBioscience | Invitrogen 17-1502-80 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD150 Monoclonal Antibody (mShad150), APC, eBioscience

catalog :

17-1502-80

quantity :

25 µg

price :

US 121

clonality :

monoclonal

host :

rat

conjugate :

APC

clone name :

mShad150

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; fig 5a	Wu X, Satpathy A, Kc W, Liu P, Murphy T, Murphy K. Bcl11a controls Flt3 expression in early hematopoietic progenitors and is required for pDC development in vivo. PLoS ONE. 2013;8:e64800 pubmed publisher
	Hohsfield L, Najafi A, Ghorbanian Y, Soni N, Hingco E, Kim S, et al. Effects of long-term and brain-wide colonization of peripheral bone marrow-derived myeloid cells in the CNS. J Neuroinflammation. 2020;17:279 pubmed publisher
	Gadomski S, Singh S, Singh S, Sarkar T, Klarmann K, Berenschot M, et al. Id1 and Id3 Maintain Steady-State Hematopoiesis by Promoting Sinusoidal Endothelial Cell Survival and Regeneration. Cell Rep. 2020;31:107572 pubmed publisher
	Guo X, Chu L, Ke F, Mu L, Li Z, Cai J, et al. Recipient bone marrow assimilates the myeloid/lymphoid reconstitution of distinct fetal hematopoietic stem cells. Oncotarget. 2017;8:108981-108988 pubmed publisher
	Zhao Y, Wu K, Nguyen C, Smbatyan G, Melendez E, Higuchi Y, et al. Small molecule p300/catenin antagonist enhances hematopoietic recovery after radiation. PLoS ONE. 2017;12:e0177245 pubmed publisher
	HENRY C, CasÃ¡s Selves M, Kim J, Zaberezhnyy V, Aghili L, Daniel A, et al. Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors. J Clin Invest. 2015;125:4666-80 pubmed publisher
	Psatha N, Sgouramali E, Gkountis A, Siametis A, Baliakas P, Constantinou V, et al. Superior long-term repopulating capacity of G-CSF+plerixafor-mobilized blood: implications for stem cell gene therapy by studies in the Hbb(th-3) mouse model. Hum Gene Ther Methods. 2014;25:317-27 pubmed publisher
	Ramkumar C, Kong Y, Trabucco S, Gerstein R, Zhang H. Smurf2 regulates hematopoietic stem cell self-renewal and aging. Aging Cell. 2014;13:478-86 pubmed publisher
	Luo B, Tseng C, Adams G, Lee A. Deficiency of GRP94 in the hematopoietic system alters proliferation regulators in hematopoietic stem cells. Stem Cells Dev. 2013;22:3062-73 pubmed publisher
	Capitano M, Nemeth M, Mace T, Salisbury Ruf C, Segal B, McCarthy P, et al. Elevating body temperature enhances hematopoiesis and neutrophil recovery after total body irradiation in an IL-1-, IL-17-, and G-CSF-dependent manner. Blood. 2012;120:2600-9 pubmed
	Satpathy A, Kc W, Albring J, Edelson B, Kretzer N, Bhattacharya D, et al. Zbtb46 expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages. J Exp Med. 2012;209:1135-52 pubmed publisher
	Ku C, Hosoya T, Maillard I, Engel J. GATA-3 regulates hematopoietic stem cell maintenance and cell-cycle entry. Blood. 2012;119:2242-51 pubmed publisher
	Schwartzberg P, Mueller K, Qi H, Cannons J. SLAM receptors and SAP influence lymphocyte interactions, development and function. Nat Rev Immunol. 2009;9:39-46 pubmed publisher
	Wilson A, Laurenti E, Oser G, van der Wath R, Blanco Bose W, Jaworski M, et al. Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair. Cell. 2008;135:1118-29 pubmed publisher
	Kiel M, Yilmaz O, Iwashita T, Yilmaz O, Terhorst C, Morrison S. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell. 2005;121:1109-21 pubmed

product information

Product Type :

Antibody

Product Name :

CD150 Monoclonal Antibody (mShad150), APC, eBioscience

Catalog # :

17-1502-80

Quantity :

25 µg

Price :

US 121

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.125 µg/test

Species :

Mouse

Clone :

mShad150

Isotype :

IgG2b, lambda

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

CD150 (SLAM, Signaling Lymphocyte Activation Molecule) belongs to the immunoglobulin gene superfamily, and is involved in T cell stimulation. SLAM is constitutively expressed on peripheral blood memory T cells, T cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation. Activated B cells express the membrane bound form, the soluble form and the cytoplasmic isoforms of SLAM. It is suggested that signalling through homophilic SLAM-SLAM binding during B to B and B to T cell interactions enhances the expansion and differentiation of activated B cells. Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T cells and B cells. Moreover, CD150 is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations CD150 gene may be associated with X-linked lympho-proliferative disease (XLP).

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.125 µg/test

Aliases :

4933415F16; AA177906; CD150; CD150 antigen; CDw150; ESTM51; IPO-3; RGD1560634; signaling lymphocyte activation molecule; signaling lymphocytic activation molecule; signaling lymphocytic activation molecule family member 1; Slam; SLAM family member 1; Slamf1

more info or order :

Invitrogen product webpage