This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD133 (Prominin-1) Monoclonal Antibody (TMP4), APC, eBioscience
catalog :
17-1338-42
quantity :
100 Tests
price :
US 414.00
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
TMP4
reactivity :
human
application :
flow cytometry
citations: 30
Reference
Liang C, Wei T, Zhang T, Niu C. Adipose‑derived stem cell‑mediated alphastatin targeting delivery system inhibits angiogenesis and tumor growth in glioma. Mol Med Rep. 2023;28: pubmed publisher
Liu Y, Xu Q, Deng F, Zheng Z, Luo J, Wang P, et al. HERC2 promotes inflammation-driven cancer stemness and immune evasion in hepatocellular carcinoma by activating STAT3 pathway. J Exp Clin Cancer Res. 2023;42:38 pubmed publisher
Guo Y, Hu G, Tian B, Ma M, Long F, Chen M. Circ_RNF13 Regulates the Stemness and Chemosensitivity of Colorectal Cancer by Transcriptional Regulation of DDX27 Mediated by TRIM24 Stabilization. Cancers (Basel). 2022;14: pubmed publisher
Xiong W, Huang X, Li C, Wang X, Lan H, Wang T, et al. Astragaloside IV - mediated endothelial progenitor cell exosomes promote autophagy and inhibit apoptosis in hyperglycemic damaged endothelial cells via miR-21/PTEN axis. Folia Histochem Cytobiol. 2022;60:323-334 pubmed publisher
Mo L, Su B, Xu L, Hu Z, Li H, Du H, et al. MCM7 supports the stemness of bladder cancer stem-like cells by enhancing autophagic flux. iScience. 2022;25:105029 pubmed publisher
Albayrak E, Akgol S, Turan R, Uslu M, Kocabas F. BML-260 promotes the growth of cord blood and mobilized peripheral blood hematopoietic stem and progenitor cells with improved reconstitution ability. J Cell Biochem. 2022;123:2009-2029 pubmed publisher
Zhou K, Sun Y, Dong D, Zhao C, Wang W. EMP3 negatively modulates breast cancer cell DNA replication, DNA damage repair, and stem-like properties. Cell Death Dis. 2021;12:844 pubmed publisher
Albayrak E, Uslu M, Akgol S, Tuysuz E, Kocabas F. Small molecule-mediated modulation of ubiquitination and neddylation improves HSC function ex vivo. J Cell Physiol. 2021;236:8122-8136 pubmed publisher
Pasquale V, Ducci G, Campioni G, Ventrici A, Assalini C, Busti S, et al. Profiling and Targeting of Energy and Redox Metabolism in Grade 2 Bladder Cancer Cells with Different Invasiveness Properties. Cells. 2020;9: pubmed publisher
Sun Y, Wang Z, Na L, Dong D, Wang W, Zhao C. FZD5 contributes to TNBC proliferation, DNA damage repair and stemness. Cell Death Dis. 2020;11:1060 pubmed publisher
Jia J, Yu F, Xiong Y, Wei W, Ma H, Nisi F, et al. Chemerin enhances the adhesion and migration of human endothelial progenitor cells and increases lipid accumulation in mice with atherosclerosis. Lipids Health Dis. 2020;19:207 pubmed publisher
Chen J, Wang L, Li R, Jiao Y, Yu W. High expression of endothelial progenitor cell-induced angiogenic markers is associated with bile acid levels in HCC. Oncol Lett. 2020;20:2729-2738 pubmed publisher
Li F, Hu Q, He T, Xu J, Yi Y, Xie S, et al. The Deubiquitinase USP4 Stabilizes Twist1 Protein to Promote Lung Cancer Cell Stemness. Cancers (Basel). 2020;12: pubmed publisher
Singh N, Padi S, Bearss J, Pandey R, Okumura K, Beltran H, et al. PIM protein kinases regulate the level of the long noncoding RNA H19 to control stem cell gene transcription and modulate tumor growth. Mol Oncol. 2020;14:974-990 pubmed publisher
Zhu D, Shao M, Yang J, Fang M, Liu S, Lou D, et al. Curcumin Enhances Radiosensitization of Nasopharyngeal Carcinoma via Mediating Regulation of Tumor Stem-like Cells by a CircRNA Network. J Cancer. 2020;11:2360-2370 pubmed publisher
Hu X, Peng W, Zhou H, Jiang J, Zhou X, Huang D, et al. IGF2BP2 regulates DANCR by serving as an N6-methyladenosine reader. Cell Death Differ. 2019;: pubmed publisher
Hocevar B. Loss of Disabled-2 Expression in Pancreatic Cancer Progression. Sci Rep. 2019;9:7532 pubmed publisher
Hung J, Kao Y, Huang C, Hsu W. Overexpression of Aiolos promotes epithelial-mesenchymal transition and cancer stem cell-like properties in lung cancer cells. Sci Rep. 2019;9:2991 pubmed publisher
Huang W, Bei L, Eklund E. Inhibition of Fas associated phosphatase 1 (Fap1) facilitates apoptosis of colon cancer stem cells and enhances the effects of oxaliplatin. Oncotarget. 2018;9:25891-25902 pubmed publisher
Kong Y, Ai C, Dong F, Xia X, Zhao X, Yang C, et al. Targeting of BMI-1 with PTC-209 inhibits glioblastoma development. Cell Cycle. 2018;17:1199-1211 pubmed publisher
Wang F, Wang A, Chesnelong C, Yang Y, Nabbi A, Thalappilly S, et al. ING5 activity in self-renewal of glioblastoma stem cells via calcium and follicle stimulating hormone pathways. Oncogene. 2018;37:286-301 pubmed publisher
Sahlberg S, Spiegelberg D, Glimelius B, Stenerlow B, Nestor M. Evaluation of cancer stem cell markers CD133, CD44, CD24: association with AKT isoforms and radiation resistance in colon cancer cells. PLoS ONE. 2014;9:e94621 pubmed publisher
Khanjani S, Khanmohammadi M, Zarnani A, Akhondi M, Ahani A, Ghaempanah Z, et al. Comparative evaluation of differentiation potential of menstrual blood- versus bone marrow-derived stem cells into hepatocyte-like cells. PLoS ONE. 2014;9:e86075 pubmed publisher
Indumathi S, Harikrishnan R, Rajkumar J, Dhanasekaran M. Immunophenotypic comparison of heterogenous non-sorted versus sorted mononuclear cells from human umbilical cord blood: a novel cell enrichment approach. Cytotechnology. 2015;67:107-14 pubmed publisher
Li C, Wu Q, Liu B, Yao Y, Chen Y, Zhang H, et al. Detection and validation of circulating endothelial cells, a blood-based diagnostic marker of acute myocardial infarction. PLoS ONE. 2013;8:e58478 pubmed publisher
Zou J, Zou P, Wang J, Li L, Wang Y, Zhou D, et al. Inhibition of p38 MAPK activity promotes ex vivo expansion of human cord blood hematopoietic stem cells. Ann Hematol. 2012;91:813-23 pubmed publisher
He J, Vu D, Hunt G, Chugh A, Bhatnagar A, Bolli R. Human cardiac stem cells isolated from atrial appendages stably express c-kit. PLoS ONE. 2011;6:e27719 pubmed publisher
O Brien C, Pollett A, Gallinger S, Dick J. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature. 2007;445:106-10 pubmed
Singh S, Hawkins C, Clarke I, Squire J, Bayani J, Hide T, et al. Identification of human brain tumour initiating cells. Nature. 2004;432:396-401 pubmed
Yin A, Miraglia S, Zanjani E, Almeida Porada G, Ogawa M, Leary A, et al. AC133, a novel marker for human hematopoietic stem and progenitor cells. Blood. 1997;90:5002-12 pubmed
product information
Product Type :
Antibody
Product Name :
CD133 (Prominin-1) Monoclonal Antibody (TMP4), APC, eBioscience
Catalog # :
17-1338-42
Quantity :
100 Tests
Price :
US 414.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 5 uL (0.125 ug)/test
Species :
Human
Clone :
TMP4
Isotype :
IgG1, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
The CD133 (AC133) antigen is a 97 kDa glycoprotein, with 5 transmembrane domains, that shows up as a 120 kDa band on protein gels due to glycosylation. CD133 is a cell surface marker expressed by immature hematopoietic stem cells but not mature blood cells. In addition to hematopoietic stem and progenitor cells, CD133 has been found to be a marker for other stem and progenitor cells including neural and embryonic stem cells. CD133 has been shown to be expressed in cancers, including some leukemias and brain tumors, that may be derived from stem cells. Low level expression could also be detected in the kidney, pancreas, placenta, and fetal liver. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of the CD133 gene is also associated with several types of cancer. CD133 is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner, and multiple transcript variants encoding different isoforms have been found.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 5 uL (0.125 ug)/test
Aliases :
4932416E19Rik; AC133; Antigen AC133; antigen AC133 homolog; antigen CD133; CD107b; CD133; CORD12; fudenine; hematopoietic stem cell antigen; hProminin; Lamp II; Lamp2; LAMP-2; Lamp-2a; Lamp-2b; Lamp-2c; LGP-96; LGP-B; Mac3; MCDR2; MSTP061; Prom; PROM1; Prom-1; prominin 1; prominin 1.s1; Prominin1; prominin-1; prominin-1.s2; prominin-like 1; prominin-like protein 1; PROML1; RP41; STGD4
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA