This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD105 (Endoglin) Monoclonal Antibody (MJ7/18), APC, eBioscience
catalog :
17-1051-80
quantity :
25 ug
price :
US 110.00
clonality :
monoclonal
host :
rat
conjugate :
APC
clone name :
MJ7/18

The same clone is also sold as:
reactivity :
mouse
application :
flow cytometry
citations: 31
Reference
Chen F, Chen Z, Wu H, Chen X, Zhan P, Wei Z, et al. Mesenchymal Stem Cell-Derived Exosomes Attenuate Murine Cytomegalovirus-Infected Pneumonia via NF-κB/NLRP3 Signaling Pathway. Viruses. 2024;16: pubmed publisher
Dushime H, Moreno S, Linard C, Adrait A, Cout xe9 Y, Peltzer J, et al. Fetal Muse-based therapy prevents lethal radio-induced gastrointestinal syndrome by intestinal regeneration. Stem Cell Res Ther. 2023;14:201 pubmed publisher
Zhou Y, Zhu P, Shen S, Wang Y, Li B, Guo B, et al. Overexpression of fibroblast growth factor receptor 2 in bone marrow mesenchymal stem cells enhances osteogenesis and promotes critical cranial bone defect regeneration. Front Cell Dev Biol. 2023;11:1208239 pubmed publisher
Kyryk V, Tsupykov O, Ustymenko A, Smozhanik E, Govbakh I, Butenko G, et al. Age-related ultrastructural changes in spheroids of the adipose-derived multipotent mesenchymal stromal cells from ovariectomized mice. Front Cell Neurosci. 2023;17:1072750 pubmed publisher
Govbakh I, Kyryk V, Ustymenko A, Rubtsov V, Tsupykov O, Bulgakova N, et al. Stem Cell Therapy Enhances Motor Activity of Triceps Surae Muscle in Mice with Hereditary Peripheral Neuropathy. Int J Mol Sci. 2021;22: pubmed publisher
Seras Franzoso J, D xed az Riascos Z, Corchero J, Gonz xe1 lez P, Garc xed a Aranda N, Manda xf1 a M, et al. Extracellular vesicles from recombinant cell factories improve the activity and efficacy of enzymes defective in lysosomal storage disorders. J Extracell Vesicles. 2021;10:e12058 pubmed publisher
Matthews B, Novak S, Sbrana F, Funnell J, Cao Y, Buckels E, et al. Heterogeneity of murine periosteum progenitors involved in fracture healing. elife. 2021;10: pubmed publisher
Wei H, Zhou W, Hu G, Shi C. Induction of mesenchymal stem cell‑like transformation in rat primary glial cells using hypoxia, mild hypothermia and growth factors. Mol Med Rep. 2021;23: pubmed publisher
Zhang C, Gu X, Zhao G, Wang W, Shao J, Zhu J, et al. Extracellular HMGB-1 activates inflammatory signaling in tendon cells and tissues. Ther Adv Chronic Dis. 2020;11:2040622320956429 pubmed publisher
Shahir M, Mahmoud Hashemi S, Asadirad A, Varahram M, Kazempour Dizaji M, Folkerts G, et al. Effect of mesenchymal stem cell-derived exosomes on the induction of mouse tolerogenic dendritic cells. J Cell Physiol. 2020;235:7043-7055 pubmed publisher
Palhinha L, Liechocki S, Hottz E, Pereira J, de Almeida C, Moraes Vieira P, et al. Leptin Induces Proadipogenic and Proinflammatory Signaling in Adipocytes. Front Endocrinol (Lausanne). 2019;10:841 pubmed publisher
Lin M, Liu X, Zheng H, Huang X, Wu Y, Huang A, et al. IGF-1 enhances BMSC viability, migration, and anti-apoptosis in myocardial infarction via secreted frizzled-related protein 2 pathway. Stem Cell Res Ther. 2020;11:22 pubmed publisher
Huang J, Zhao L, Fan Y, Liao L, Ma P, Xiao G, et al. The microRNAs miR-204 and miR-211 maintain joint homeostasis and protect against osteoarthritis progression. Nat Commun. 2019;10:2876 pubmed publisher
Yu B, Li Q, Zhou M. LPS‑induced upregulation of the TLR4 signaling pathway inhibits osteogenic differentiation of human periodontal ligament stem cells under inflammatory conditions. Int J Mol Med. 2019;43:2341-2351 pubmed publisher
Stivala S, Codilupi T, Brkic S, Baerenwaldt A, Ghosh N, Hao Shen H, et al. Targeting compensatory MEK/ERK activation increases JAK inhibitor efficacy in myeloproliferative neoplasms. J Clin Invest. 2019;130:1596-1611 pubmed publisher
Gulati G, Murphy M, Marecic O, Lopez M, Brewer R, Koepke L, et al. Isolation and functional assessment of mouse skeletal stem cell lineage. Nat Protoc. 2018;13:1294-1309 pubmed publisher
Ge J, Burnier L, Adamopoulou M, Kwa M, Schaks M, Rottner K, et al. RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells. J Biol Chem. 2018;293:9358-9369 pubmed publisher
Redgrave R, Tual Chalot S, Davison B, Singh E, Hall D, Amirrasouli M, et al. Cardiosphere-Derived Cells Require Endoglin for Paracrine-Mediated Angiogenesis. Stem Cell Reports. 2017;8:1287-1298 pubmed publisher
Yu Q, Song W, Wang D, Zeng Y. Identification of blood vascular endothelial stem cells by the expression of protein C receptor. Cell Res. 2016;26:1079-1098 pubmed publisher
Ojeda Fernandez L, Recio Poveda L, Aristorena M, Lastres P, Blanco F, Sanz Rodriguez F, et al. Mice Lacking Endoglin in Macrophages Show an Impaired Immune Response. PLoS Genet. 2016;12:e1005935 pubmed publisher
Zafir A, Bradley J, Long B, Muthusamy S, Li Q, Hill B, et al. O-GlcNAcylation Negatively Regulates Cardiomyogenic Fate in Adult Mouse Cardiac Mesenchymal Stromal Cells. PLoS ONE. 2015;10:e0142939 pubmed publisher
Jeong Ryu S, Ju J, Kim W, Bum Kim M, Hee Oh K, Sup Lee D, et al. Alleviation of skin inflammation after Lin(-) cell transplantation correlates with their differentiation into myeloid-derived suppressor cells. Sci Rep. 2015;5:14663 pubmed publisher
Shankman L, Gomez D, Cherepanova O, Salmon M, Alencar G, Haskins R, et al. KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis. Nat Med. 2015;21:628-37 pubmed publisher
Cheng C, Lee Y, Lin S, HuangFu W, Liu I. Cell-autonomous heparanase modulates self-renewal and migration in bone marrow-derived mesenchymal stem cells. J Biomed Sci. 2014;21:21 pubmed publisher
Cheng C, Lian W, Hsiao F, Liu I, Lin S, Lee Y, et al. Isolation and characterization of novel murine epiphysis derived mesenchymal stem cells. PLoS ONE. 2012;7:e36085 pubmed publisher
Yan A, Avraham T, Zampell J, Haviv Y, Weitman E, Mehrara B. Adipose-derived stem cells promote lymphangiogenesis in response to VEGF-C stimulation or TGF-?1 inhibition. Future Oncol. 2011;7:1457-73 pubmed publisher
Wu X, Yu G, Parks H, Hebert T, Goh B, Dietrich M, et al. Circadian mechanisms in murine and human bone marrow mesenchymal stem cells following dexamethasone exposure. Bone. 2008;42:861-70 pubmed publisher
Perez Gomez E, Villa Morales M, Santos J, Fernandez Piqueras J, Gamallo C, Dotor J, et al. A role for endoglin as a suppressor of malignancy during mouse skin carcinogenesis. Cancer Res. 2007;67:10268-77 pubmed
Korpanty G, Carbon J, Grayburn P, Fleming J, Brekken R. Monitoring response to anticancer therapy by targeting microbubbles to tumor vasculature. Clin Cancer Res. 2007;13:323-30 pubmed
Onoe T, Ohdan H, Tokita D, Shishida M, Tanaka Y, Hara H, et al. Liver sinusoidal endothelial cells tolerize T cells across MHC barriers in mice. J Immunol. 2005;175:139-46 pubmed
Quintanilla M, Ramirez J, Perez Gomez E, Romero D, Velasco B, Letarte M, et al. Expression of the TGF-beta coreceptor endoglin in epidermal keratinocytes and its dual role in multistage mouse skin carcinogenesis. Oncogene. 2003;22:5976-85 pubmed
product information
Product Type :
Antibody
Product Name :
CD105 (Endoglin) Monoclonal Antibody (MJ7/18), APC, eBioscience
Catalog # :
17-1051-80
Quantity :
25 ug
Price :
US 110.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.125 ug/test
Species :
Mouse
Clone :
MJ7/18
Isotype :
IgG2a, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.125 ug/test
Aliases :
AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); Eng; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA