CD103 (Integrin alpha E) Monoclonal Antibody (Ber-ACT8), APC, eBioscience | Invitrogen 17-1037-42 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD103 (Integrin alpha E) Monoclonal Antibody (Ber-ACT8), APC, eBioscience

catalog :

17-1037-42

quantity :

100 Tests

price :

US 346.00

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

Ber-ACT8

The same clone is also sold as:

Exbio: 11-670-C025, 1P-670-T100, 11-670-C100, 1A-670-T100, 1P-670-T025, 1A-670-T025, 1F-670-T100, 1F-670-T025
BD Biosciences: 550259, 550258, 561677, 550260, 340945, 340944, 564346
OriGene: AM26142PU-N, AM26142AC-N, AM26142FC-N, AM26142RP-N
Santa Cruz Biotechnology: sc-19981 HRP, sc-19981, sc-19981 AC
Novus Biologicals: NBP1-97564
BioLegend: 350210, 260328, 260330, 350255, 350254, 350202, 350227, 350228, 350231, 350248, 350205, 350204, 350238, 350226, 350203, 984808, 984806, 350253, 350237, 350212, 350211, 350245, 984804, 350213, 350224, 350225, 350216, 350243, 350221, 350233, 350206, 350222, 350241, 350208, 350256, 350230, 350249, 350209, 350217, 350215, 350229, 350218, 350250, 350247, 285063, 350246, 350220, 350214, 350223, 350244, 350239, 350240, 350251, 350235

reactivity :

human

application :

flow cytometry

citations: 7

Reference
El Houseini M, Arafat M, El Husseiny A, Kasem I, Kamel M, El Habashy A, et al. Biological and molecular studies on specific immune cells treated with checkpoint inhibitors for the thera-personal approach of breast cancer patients (ex-vivo study). Oncol Res. 2021;29:319-330 pubmed publisher
Duhen R, Ballesteros Merino C, Frye A, Tran E, Rajamanickam V, Chang S, et al. Neoadjuvant anti-OX40 (MEDI6469) therapy in patients with head and neck squamous cell carcinoma activates and expands antigen-specific tumor-infiltrating T cells. Nat Commun. 2021;12:1047 pubmed publisher
Hamilton E, Pearce L, Morgan L, Robinson S, Ware V, Brennan P, et al. Mimicking the tumour microenvironment: three different co-culture systems induce a similar phenotype but distinct proliferative signals in primary chronic lymphocytic leukaemia cells. Br J Haematol. 2012;158:589-99 pubmed publisher
Hovhannisyan Z, Treatman J, Littman D, Mayer L. Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases. Gastroenterology. 2011;140:957-65 pubmed publisher
Cardoso C, Garlet G, Moreira A, Júnior W, Rossi M, Silva J. Characterization of CD4+CD25+ natural regulatory T cells in the inflammatory infiltrate of human chronic periodontitis. J Leukoc Biol. 2008;84:311-8 pubmed publisher
Cavassani K, Campanelli A, Moreira A, Vancim J, Vitali L, Mamede R, et al. Systemic and local characterization of regulatory T cells in a chronic fungal infection in humans. J Immunol. 2006;177:5811-8 pubmed
Kruschwitz M, Fritzsche G, Schwarting R, Micklem K, Mason D, Falini B, et al. Ber-ACT8: new monoclonal antibody to the mucosa lymphocyte antigen. J Clin Pathol. 1991;44:636-45 pubmed

product information

Product Type :

Antibody

Product Name :

CD103 (Integrin alpha E) Monoclonal Antibody (Ber-ACT8), APC, eBioscience

Catalog # :

17-1037-42

Quantity :

100 Tests

Price :

US 346.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (0.06 ug)/test

Species :

Human

Clone :

Ber-ACT8

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

CD103 (ITGAE, Integrin alpha E) is molecule that is expressed on mucosa-associated T lymphocytes and activated cells and on subet of TGF beta -1 cells. In particular, CD103 includes a 150kDa alpha chain and a 120kDa beta chain. CD103 is expressed by 0.5 to 2% of resting lymphocytes in peripheral blood and lymphoid organs. CD103 antibody stains a few bone marrow cells and, rarely, peripheral blood lymphocytes. CD103 is part of the integrin family which are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. ITGAE encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, CD103 protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. CD103 is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. Diseases associated with CD103 dysfunction include hairy cell leukemia and splenic marginal zone lymphoma.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (0.06 ug)/test

Aliases :

A530055J10; alpha-E1; alpha-M290; aM290; antigen CD103; antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide; CD103; DC; DCs; HML-1 antigen; human mucosal lymphocyte antigen 1, alpha polypeptide; HUMINAE; integrin alpha E; integrin alpha E, epithelial-associated; integrin alpha E1, epithelial-associated; integrin alpha M290; Integrin alpha-E; Integrin alpha-E heavy chain; Integrin alpha-E light chain; Integrin alpha-IEL; integrin subunit alpha E; integrin, alpha E; integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide); integrin, alpha E, epithelial-associated; Intregrin alpha E2; Itgae; MGC141996; Mucosal lymphocyte 1 antigen