This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD66b Monoclonal Antibody (G10F5), APC, eBioscience
catalog :
17-0666-42
quantity :
100 Tests
price :
US 366.00
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
G10F5

The same clone is also sold as:
reactivity :
human
application :
flow cytometry
citations: 17
Reference
Hopke A, Lin T, Scherer A, Shay A, Timmer K, Wilson Mifsud B, et al. Transcellular biosynthesis of leukotriene B4 orchestrates neutrophil swarming to fungi. iScience. 2022;25:105226 pubmed publisher
Liu D, Li Q, Ding H, Zhao G, Wang Z, Cao C, et al. Placenta-derived IL-32β activates neutrophils to promote preeclampsia development. Cell Mol Immunol. 2021;18:979-991 pubmed publisher
Palace S, Vitseva O, Proulx M, Freedman J, Goguen J, Koupenova M. Yersinia pestis escapes entrapment in thrombi by targeting platelet function. J Thromb Haemost. 2020;18:3236-3248 pubmed publisher
Hernandez J, Tew B, Li T, Gooden G, Ghannam H, Masuda M, et al. A FACS-based approach to obtain viable eosinophils from human adipose tissue. Sci Rep. 2020;10:13210 pubmed publisher
Drescher H, Schippers A, Rosenhain S, Gremse F, Bongiovanni L, Bruin A, et al. L-Selectin/CD62L is a Key Driver of Non-Alcoholic Steatohepatitis in Mice and Men. Cells. 2020;9: pubmed publisher
Markman J, Porritt R, Wakita D, Lane M, Martinon D, Noval Rivas M, et al. Loss of testosterone impairs anti-tumor neutrophil function. Nat Commun. 2020;11:1613 pubmed publisher
Koupenova M, Corkrey H, Vitseva O, Manni G, Pang C, Clancy L, et al. The role of platelets in mediating a response to human influenza infection. Nat Commun. 2019;10:1780 pubmed publisher
Shanmugasundaram U, Critchfield J, Pannell J, Perry J, Giudice L, Smith McCune K, et al. Phenotype and functionality of CD4+ and CD8+ T cells in the upper reproductive tract of healthy premenopausal women. Am J Reprod Immunol. 2014;71:95-108 pubmed publisher
McFarlin B, Williams R, Venable A, Dwyer K, Haviland D. Image-based cytometry reveals three distinct subsets of activated granulocytes based on phagocytosis and oxidative burst. Cytometry A. 2013;83:745-51 pubmed publisher
Lindau D, Mussard J, Wagner B, Ribon M, Rönnefarth V, Quettier M, et al. Primary blood neutrophils express a functional cell surface Toll-like receptor 9. Eur J Immunol. 2013;43:2101-13 pubmed publisher
Simhadri V, Mariano J, Gil Krzewska A, Zhou Q, Borrego F. CD300c is an activating receptor expressed on human monocytes. J Innate Immun. 2013;5:389-400 pubmed publisher
Zhou L, Somasundaram R, Nederhof R, Dijkstra G, Faber K, Peppelenbosch M, et al. Impact of human granulocyte and monocyte isolation procedures on functional studies. Clin Vaccine Immunol. 2012;19:1065-74 pubmed publisher
Norling L, Dalli J, Flower R, Serhan C, Perretti M. Resolvin D1 limits polymorphonuclear leukocyte recruitment to inflammatory loci: receptor-dependent actions. Arterioscler Thromb Vasc Biol. 2012;32:1970-8 pubmed publisher
Schmidt T, Zundorf J, Gruger T, Brandenburg K, Reiners A, Zinserling J, et al. CD66b overexpression and homotypic aggregation of human peripheral blood neutrophils after activation by a gram-positive stimulus. J Leukoc Biol. 2012;91:791-802 pubmed publisher
Jensen T, Schmidt H, Møller H, Donskov F, Høyer M, Sjoegren P, et al. Intratumoral neutrophils and plasmacytoid dendritic cells indicate poor prognosis and are associated with pSTAT3 expression in AJCC stage I/II melanoma. Cancer. 2012;118:2476-85 pubmed publisher
Lechner M, Megiel C, Russell S, Bingham B, Arger N, Woo T, et al. Functional characterization of human Cd33+ and Cd11b+ myeloid-derived suppressor cell subsets induced from peripheral blood mononuclear cells co-cultured with a diverse set of human tumor cell lines. J Transl Med. 2011;9:90 pubmed publisher
Skubitz K, Campbell K, Skubitz A. CD66a, CD66b, CD66c, and CD66d each independently stimulate neutrophils. J Leukoc Biol. 1996;60:106-17 pubmed
product information
Product Type :
Antibody
Product Name :
CD66b Monoclonal Antibody (G10F5), APC, eBioscience
Catalog # :
17-0666-42
Quantity :
100 Tests
Price :
US 366.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 5 uL (0.125 ug)/test
Species :
Human
Clone :
G10F5
Isotype :
IgM, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 5 uL (0.125 ug)/test
Aliases :
carcinoembryonic antigen CGM6; carcinoembryonic antigen gene family member 6; carcinoembryonic antigen related cell adhesion molecule 8; carcinoembryonic antigen-related cell adhesion molecule 8; CD66b; CD67; CD67 antigen; CEACAM8; CGM6; NCA-95; non-specific cross-reacting antigen NCA-95
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA