CD66a (CEACAM1) Monoclonal Antibody (CC1), APC, eBioscience | Invitrogen 17-0661-80 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD66a (CEACAM1) Monoclonal Antibody (CC1), APC, eBioscience

catalog :

17-0661-80

quantity :

25 ug

price :

US 158.00

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

CC1

The same clone is also sold as:

Novus Biologicals: NBP1-43390-0.1mg

reactivity :

mouse

application :

flow cytometry

citations: 7

Reference
Chiang H, Lu H, Sudhakar J, Chen Y, Shih N, Weng Y, et al. IL-22 initiates an IL-18-dependent epithelial response circuit to enforce intestinal host defence. Nat Commun. 2022;13:874 pubmed publisher
Dao T, Utturkar S, Atallah Lanman N, Matosevic S. TIM-3 Expression Is Downregulated on Human NK Cells in Response to Cancer Targets in Synergy with Activation. Cancers (Basel). 2020;12: pubmed publisher
Thirion G, Feliu A, Coutelier J. CD66a (CEACAM1) expression by mouse natural killer cells. Immunology. 2008;125:535-40 pubmed publisher
Nakagaki K, Nakagaki K, Taguchi F. Receptor-independent spread of a highly neurotropic murine coronavirus JHMV strain from initially infected microglial cells in mixed neural cultures. J Virol. 2005;79:6102-10 pubmed
Turner B, Hemmila E, Beauchemin N, Holmes K. Receptor-dependent coronavirus infection of dendritic cells. J Virol. 2004;78:5486-90 pubmed
Greicius G, Severinson E, Beauchemin N, Obrink B, Singer B. CEACAM1 is a potent regulator of B cell receptor complex-induced activation. J Leukoc Biol. 2003;74:126-34 pubmed
Kammerer R, Stober D, Singer B, Obrink B, Reimann J. Carcinoembryonic antigen-related cell adhesion molecule 1 on murine dendritic cells is a potent regulator of T cell stimulation. J Immunol. 2001;166:6537-44 pubmed

product information

Product Type :

Antibody

Product Name :

CD66a (CEACAM1) Monoclonal Antibody (CC1), APC, eBioscience

Catalog # :

17-0661-80

Quantity :

25 ug

Price :

US 158.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.06 ug/test

Species :

Mouse

Clone :

CC1

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

CEACAM1 is a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of only two has been determined.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.06 ug/test

Aliases :

antigen CD66; ATP-dependent taurocolate-carrier protein; bb-1; BGP; BGP1; BGP-1; BGPI; BGPR; Biliary glycoprotein 1; biliary glycoprotein D; bone gamma-carboxyglutamic acid (Gla) protein; carcinoembryonic antigen 1; carcinoembryonic antigen 7; carcinoembryonic antigen related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein); Cc1; C-CAM; C-CAM 105; Ccam1; CD66a; CD66a antigen; Cea1; Cea-1; Cea7; Cea-7; CEACAM1; CEA-related cell adhesion molecule 1; CEA-related cell adhesion molecule 1 (bone gamma-carboxyglutamic acid (Gla) protein) (osteocalcin); Cell-CAM 105; ecto-ATPase; GP110; hepatitis virus (MHV-4) susceptibility; hepatitis virus receptor; Hv2; Hv-2; mCEA1; Mhv-1; MHVR; MHV-R; MHVR1; mmCGM1; mmCGM1a; mmCGM2; murine hepatitis virus receptor; osteocalcin; pp120; pp120/ecto-ATPase