This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD58 (LFA-3) Monoclonal Antibody (TS2/9), APC, eBioscience
catalog :
17-0578-42
quantity :
100 Tests
price :
US 336.00
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
TS2/9

The same clone is also sold as:
reactivity :
human
application :
flow cytometry
citations: 6
Reference
Nguyen C, Domma A, Zhang H, Kamil J. Endoplasmic Reticulum (ER) Reorganization and Intracellular Retention of CD58 Are Functionally Independent Properties of the Human Cytomegalovirus ER-Resident Glycoprotein UL148. J Virol. 2020;94: pubmed publisher
Ariel O, Levi Y, Hollander N. Signal transduction by CD58: the transmembrane isoform transmits signals outside lipid rafts independently of the GPI-anchored isoform. Cell Signal. 2009;21:1100-8 pubmed publisher
Hahn W, Burakoff S, Bierer B. Signal transduction pathways involved in T cell receptor-induced regulation of CD2 avidity for CD58. J Immunol. 1993;150:2607-19 pubmed
Osborn L, Day E, Miller G, Karpusas M, Tizard R, Meuer S, et al. Amino acid residues required for binding of lymphocyte function-associated antigen 3 (CD58) to its counter-receptor CD2. J Exp Med. 1995;181:429-34 pubmed
Diaz Sanchez D, Chegini S, Zhang K, Saxon A. CD58 (LFA-3) stimulation provides a signal for human isotype switching and IgE production distinct from CD40. J Immunol. 1994;153:10-20 pubmed
Sanchez Madrid F, Krensky A, Ware C, Robbins E, Strominger J, Burakoff S, et al. Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. Proc Natl Acad Sci U S A. 1982;79:7489-93 pubmed
product information
Product Type :
Antibody
Product Name :
CD58 (LFA-3) Monoclonal Antibody (TS2/9), APC, eBioscience
Catalog # :
17-0578-42
Quantity :
100 Tests
Price :
US 336.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 5 uL (0.5 ug)/test
Species :
Human
Clone :
TS2/9
Isotype :
IgG1, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 5 uL (0.5 ug)/test
Aliases :
Ag3; CD305; CD58; CD58 antigen; CD58 antigen, (lymphocyte function-associated antigen 3); CD58 molecule; FLJ23181; FLJ43722; LAIR1; LAIR-1; LFA3; LFA-3; Lymphocyte function-associated antigen 3; membrane receptor; RP5-1086K13.2; surface glycoprotein LFA-3
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA