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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD56 (NCAM) Monoclonal Antibody (CMSSB), APC, eBioscience
catalog :
17-0567-42
quantity :
100 Tests
price :
US 311
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
CMSSB
reactivity :
human
application :
flow cytometry
more info or order :
Invitrogen product webpage
citations: 27
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human
Tichy E, Ma N, Sidibe D, Loro E, Kocan J, Chen D, et al. Persistent NF-κB activation in muscle stem cells induces proliferation-independent telomere shortening. Cell Rep. 2021;35:109098 pubmed publisher
  • flow cytometry; human; tbl 1
Magri G, Miyajima M, Bascones S, Mortha A, Puga I, Cassis L, et al. Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells. Nat Immunol. 2014;15:354-364 pubmed publisher
Black J, McCutcheon S, Dube S, Barrera A, Klann T, Rice G, et al. Master Regulators and Cofactors of Human Neuronal Cell Fate Specification Identified by CRISPR Gene Activation Screens. Cell Rep. 2020;33:108460 pubmed publisher
Goloviznina N, Xie N, Dandapat A, Iaizzo P, Kyba M. Prospective isolation of human fibroadipogenic progenitors with CD73. Heliyon. 2020;6:e04503 pubmed publisher
Zou Y, Liang J, Li D, Fang J, Wang L, Wang J, et al. Application of the chemokine-chemokine receptor axis increases the tumor-targeted migration ability of cytokine-induced killer cells in patients with colorectal cancer. Oncol Lett. 2020;20:123-134 pubmed publisher
Schulte L, Schweinlin M, Westermann A, Janga H, Santos S, Appenzeller S, et al. An Advanced Human Intestinal Coculture Model Reveals Compartmentalized Host and Pathogen Strategies during Salmonella Infection. MBio. 2020;11: pubmed publisher
Tiwari R, Manzar N, Bhatia V, Yadav A, Nengroo M, Datta D, et al. Androgen deprivation upregulates SPINK1 expression and potentiates cellular plasticity in prostate cancer. Nat Commun. 2020;11:384 pubmed publisher
Pan M, Wu C, Kan J, Li Q, Chang S, Wu C, et al. Impact of FAK Expression on the Cytotoxic Effects of CIK Therapy in Triple-Negative Breast Cancer. Cancers (Basel). 2019;12: pubmed publisher
Klöss V, Grünvogel O, Wabnitz G, Eigenbrod T, Ehrhardt S, Lasitschka F, et al. Interaction and Mutual Activation of Different Innate Immune Cells Is Necessary to Kill and Clear Hepatitis C Virus-Infected Cells. Front Immunol. 2017;8:1238 pubmed publisher
Cobb D, Kim O, Golden Mason L, Rosen H, Hahn Y. Hepatocyte-derived exosomes promote T follicular regulatory cell expansion during hepatitis C virus infection. Hepatology. 2017;: pubmed publisher
Cui R, Rekasi H, Hepner Schefczyk M, Fessmann K, Petri R, Bruderek K, et al. Human mesenchymal stromal/stem cells acquire immunostimulatory capacity upon cross-talk with natural killer cells and might improve the NK cell function of immunocompromised patients. Stem Cell Res Ther. 2016;7:88 pubmed publisher
Manson J, Cole E, De Ath H, Vulliamy P, Meier U, Pennington D, et al. Early changes within the lymphocyte population are associated with the development of multiple organ dysfunction syndrome in trauma patients. Crit Care. 2016;20:176 pubmed publisher
Soh K, Tario J, Colligan S, Maguire O, Pan D, Minderman H, et al. Simultaneous, Single-Cell Measurement of Messenger RNA, Cell Surface Proteins, and Intracellular Proteins. Curr Protoc Cytom. 2016;75:7.45.1-7.45.33 pubmed publisher
Bhanu N, Sidoli S, Garcia B. Histone modification profiling reveals differential signatures associated with human embryonic stem cell self-renewal and differentiation. Proteomics. 2016;16:448-58 pubmed publisher
Spiesberger K, Paulfranz F, Egger A, Reiser J, Vogl C, Rudolf Scholik J, et al. Large-Scale Purification of r28M: A Bispecific scFv Antibody Targeting Human Melanoma Produced in Transgenic Cattle. PLoS ONE. 2015;10:e0140471 pubmed publisher
Moraru M, Black L, Muntasell A, Portero F, López Botet M, Reyburn H, et al. NK Cell and Ig Interplay in Defense against Herpes Simplex Virus Type 1: Epistatic Interaction of CD16A and IgG1 Allotypes of Variable Affinities Modulates Antibody-Dependent Cellular Cytotoxicity and Susceptibility to Clinical Reactivation. J Immunol. 2015;195:1676-84 pubmed publisher
Reinhardt R, Pohlmann S, Kleinertz H, Hepner Schefczyk M, Paul A, Flohé S. Invasive Surgery Impairs the Regulatory Function of Human CD56 bright Natural Killer Cells in Response to Staphylococcus aureus. Suppression of Interferon-? Synthesis. PLoS ONE. 2015;10:e0130155 pubmed publisher
Thomas H, Jager M, Mauel K, Brandau S, Lask S, Flohé S. Interaction with mesenchymal stem cells provokes natural killer cells for enhanced IL-12/IL-18-induced interferon-gamma secretion. Mediators Inflamm. 2014;2014:143463 pubmed publisher
Tittarelli A, Mendoza Naranjo A, Farías M, Guerrero I, Ihara F, Wennerberg E, et al. Gap junction intercellular communications regulate NK cell activation and modulate NK cytotoxic capacity. J Immunol. 2014;192:1313-9 pubmed publisher
Peruzzi G, Femnou L, Gil Krzewska A, Borrego F, Weck J, Krzewski K, et al. Membrane-type 6 matrix metalloproteinase regulates the activation-induced downmodulation of CD16 in human primary NK cells. J Immunol. 2013;191:1883-94 pubmed publisher
Turaç G, Hindley C, Thomas R, Davis J, Deleidi M, Gasser T, et al. Combined flow cytometric analysis of surface and intracellular antigens reveals surface molecule markers of human neuropoiesis. PLoS ONE. 2013;8:e68519 pubmed publisher
Albini S, Coutinho P, Malecova B, Giordani L, Savchenko A, Forcales S, et al. Epigenetic reprogramming of human embryonic stem cells into skeletal muscle cells and generation of contractile myospheres. Cell Rep. 2013;3:661-70 pubmed publisher
Lim O, Lee Y, Chung H, Her J, Kang S, Jung M, et al. GMP-compliant, large-scale expanded allogeneic natural killer cells have potent cytolytic activity against cancer cells in vitro and in vivo. PLoS ONE. 2013;8:e53611 pubmed publisher
Miki Y, Gion Y, Mukae Y, Hayashi A, Sato H, Yoshino T, et al. Morphologic, flow cytometric, functional, and molecular analyses of S100B positive lymphocytes, unique cytotoxic lymphocytes containing S100B protein. Eur J Haematol. 2013;90:99-110 pubmed publisher
Sonnenberg G, Monticelli L, Alenghat T, Fung T, Hutnick N, Kunisawa J, et al. Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria. Science. 2012;336:1321-5 pubmed publisher
Gorska M, Alam R. A mutation in the human Uncoordinated 119 gene impairs TCR signaling and is associated with CD4 lymphopenia. Blood. 2012;119:1399-406 pubmed publisher
McAlpine S, Issekutz T, Marshall J. Virus stimulation of human mast cells results in the recruitment of CD56? T cells by a mechanism dependent on CCR5 ligands. FASEB J. 2012;26:1280-9 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CD56 (NCAM) Monoclonal Antibody (CMSSB), APC, eBioscience
Catalog # :
17-0567-42
Quantity :
100 Tests
Price :
US 311
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 5 µL (0.125 µg)/test
Species :
Human
Clone :
CMSSB
Isotype :
IgG1, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of the immunoglobulin family that serves as an adhesive molecule and is ubiquitously expressed in the nervous system in isoforms ranging from 120-180 kDa. CD56 is found on T cells and NK cells, and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. Polysialic modification results in reduction of CD56-mediated cell adhesion. Through its extracellular region, CD56 mediates homophilic and heterophilic interactions by binding extracellular matrix components such as laminin and integrins. CD56 is expressed on most neuroectodermal derived cell lines, tissues and neoplasms such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma. Further, CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumors and ovarian granulosa cell tumors. Diseases associated with CD56 dysfunction include rabies and blastic plasmacytoid dendritic cell neoplasms.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 5 µL (0.125 µg)/test
Aliases :
adhesion molecule; antigen recognized by monoclonal antibody 5.1H11; Cd56; CD-56; CD56 120 kDa GPI-linked isoform; CD56 140 kDa isoform; CD56 140 kDa VASE isoform; E NCAM; E-NCAM; MSK39; N CAM1; NCAM; N-CAM; Ncam1; N-CAM-1; NCAM-1; NCAMC; NCAM-C; neural cell adhesion molecule; Neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; sCD56; sNCAM; soluble CD56; soluble NCAM
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA