CD56 (NCAM) Monoclonal Antibody (TULY56), APC, eBioscience™ | Invitrogen 17-0566-42 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD56 (NCAM) Monoclonal Antibody (TULY56), APC, eBioscience™

catalog :

17-0566-42

quantity :

100 Tests

price :

US 309.00

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

TULY56

reactivity :

human, rhesus macaque

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig 6a, s11, s12c	Zou F, Lu L, Liu J, Xia B, Zhang W, Hu Q, et al. Engineered triple inhibitory receptor resistance improves anti-tumor CAR-T cell performance via CD56. Nat Commun. 2019;10:4109 pubmed publisher
	Yang C, Siebert J, Burns R, Gerbec Z, Bonacci B, Rymaszewski A, et al. Heterogeneity of human bone marrow and blood natural killer cells defined by single-cell transcriptome. Nat Commun. 2019;10:3931 pubmed publisher
	Salyer A, David S. Transcriptomal signatures of vaccine adjuvants and accessory immunostimulation of sentinel cells by toll-like receptor 2/6 agonists. Hum Vaccin Immunother. 2018;14:1686-1696 pubmed publisher
	Yu Y, Gool E, Berckmans R, Coumans F, Barendrecht A, Maas C, et al. Extracellular vesicles from human saliva promote hemostasis by delivering coagulant tissue factor to activated platelets. J Thromb Haemost. 2018;16:1153-1163 pubmed publisher
	Xiao Q, Wu J, Wang W, Chen S, Zheng Y, Yu X, et al. DKK2 imparts tumor immunity evasion through β-catenin-independent suppression of cytotoxic immune-cell activation. Nat Med. 2018;24:262-270 pubmed publisher
	Walker W, Kurscheid S, Joshi S, Lopez C, Goh G, Choi M, et al. Increased Levels of Macrophage Inflammatory Proteins Result in Resistance to R5-Tropic HIV-1 in a Subset of Elite Controllers. J Virol. 2015;89:5502-14 pubmed publisher
	Sonnenberg G, Monticelli L, Alenghat T, Fung T, Hutnick N, Kunisawa J, et al. Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria. Science. 2012;336:1321-5 pubmed publisher
	Hayakawa Y, Huntington N, Nutt S, Smyth M. Functional subsets of mouse natural killer cells. Immunol Rev. 2006;214:47-55 pubmed

product information

Product Type :

Antibody

Product Name :

CD56 (NCAM) Monoclonal Antibody (TULY56), APC, eBioscience™

Catalog # :

17-0566-42

Quantity :

100 Tests

Price :

US 309.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human, Non-human primate, Rhesus Monkey

Applications :

Flow Cytometry: 5 µL (0.125 µg)/test

Species :

Human, Non-human primate, Rhesus Monkey

Clone :

TULY56

Isotype :

IgG1, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of the immunoglobulin family that serves as an adhesive molecule and is ubiquitously expressed in the nervous system in isoforms ranging from 120-180 kDa. CD56 is found on T cells and NK cells, and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. Polysialic modification results in reduction of CD56-mediated cell adhesion. Through its extracellular region, CD56 mediates homophilic and heterophilic interactions by binding extracellular matrix components such as laminin and integrins. CD56 is expressed on most neuroectodermal derived cell lines, tissues and neoplasms such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma. Further, CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumors and ovarian granulosa cell tumors. Diseases associated with CD56 dysfunction include rabies and blastic plasmacytoid dendritic cell neoplasms.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 µL (0.125 µg)/test

Aliases :

adhesion molecule; antigen recognized by monoclonal antibody 5.1H11; Cd56; CD-56; CD56 120 kDa GPI-linked isoform; CD56 140 kDa isoform; CD56 140 kDa VASE isoform; E NCAM; E-NCAM; MSK39; N CAM1; NCAM; N-CAM; Ncam1; N-CAM-1; NCAM-1; NCAMC; NCAM-C; neural cell adhesion molecule; Neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; sCD56; sNCAM; soluble CD56; soluble NCAM

more info or order :

Invitrogen product webpage