CD56 (NCAM) Monoclonal Antibody (TULY56), APC, eBioscience | Invitrogen 17-0566-41 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD56 (NCAM) Monoclonal Antibody (TULY56), APC, eBioscience

catalog :

17-0566-41

quantity :

25 Tests

price :

US 148.00

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

TULY56

reactivity :

human, rhesus macaque

application :

flow cytometry

citations: 17

Reference
Dong W, Li W, Zhang S, Zeng X, Qin Q, Fan H, et al. Exhaustion‑like dysfunction of T and NKT cells in an X‑linked severe combined immunodeficiency patient with maternal engraftment by single‑cell analysis. Int J Mol Med. 2023;51: pubmed publisher
Fischer D, Ansari M, Wagner K, Jarosch S, Huang Y, Mayr C, et al. Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through 'reverse phenotyping'. Nat Commun. 2021;12:4515 pubmed publisher
Satria R, Huang T, Jhan M, Shen T, Tseng P, Wang Y, et al. Increased TNF-α Initiates Cytoplasmic Vacuolization in Whole Blood Coculture with Dengue Virus. J Immunol Res. 2021;2021:6654617 pubmed publisher
Rubio Perez C, Planas Rigol E, Trincado J, Bonfill Teixidor E, Arias A, Marchese D, et al. Immune cell profiling of the cerebrospinal fluid enables the characterization of the brain metastasis microenvironment. Nat Commun. 2021;12:1503 pubmed publisher
Louka E, Povinelli B, Rodriguez Meira A, Buck G, Wen W, Wang G, et al. Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia. J Exp Med. 2021;218: pubmed publisher
Kim Y, Park S, Ha H, Lee A, Won H, Cha H, et al. HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment. J Cancer. 2020;11:4059-4072 pubmed publisher
Kwon J, Vankara A, Ettyreddy A, Bohning J, Gersbach C. Myogenic Progenitor Cell Lineage Specification by CRISPR/Cas9-Based Transcriptional Activators. Stem Cell Reports. 2020;14:755-769 pubmed publisher
Grutza R, Moskorz W, Senff T, B xe4 cker E, Lindemann M, Zimmermann A, et al. NKG2Cpos NK Cells Regulate the Expansion of Cytomegalovirus-Specific CD8 T Cells. J Immunol. 2020;204:2910-2917 pubmed publisher
Zou F, Lu L, Liu J, Xia B, Zhang W, Hu Q, et al. Engineered triple inhibitory receptor resistance improves anti-tumor CAR-T cell performance via CD56. Nat Commun. 2019;10:4109 pubmed publisher
Yang C, Siebert J, Burns R, Gerbec Z, Bonacci B, Rymaszewski A, et al. Heterogeneity of human bone marrow and blood natural killer cells defined by single-cell transcriptome. Nat Commun. 2019;10:3931 pubmed publisher
Salyer A, David S. Transcriptomal signatures of vaccine adjuvants and accessory immunostimulation of sentinel cells by toll-like receptor 2/6 agonists. Hum Vaccin Immunother. 2018;14:1686-1696 pubmed publisher
Yu Y, Gool E, Berckmans R, Coumans F, Barendrecht A, Maas C, et al. Extracellular vesicles from human saliva promote hemostasis by delivering coagulant tissue factor to activated platelets. J Thromb Haemost. 2018;16:1153-1163 pubmed publisher
Xiao Q, Wu J, Wang W, Chen S, Zheng Y, Yu X, et al. DKK2 imparts tumor immunity evasion through β-catenin-independent suppression of cytotoxic immune-cell activation. Nat Med. 2018;24:262-270 pubmed publisher
Albayati Z, Alyami A, Alomar S, Middleton D, Bonnett L, Aleem S, et al. The Influence of Cytomegalovirus on Expression of HLA-G and its Ligand KIR2DL4 by Human Peripheral Blood Leucocyte Subsets. Scand J Immunol. 2017;86:396-407 pubmed publisher
Walker W, Kurscheid S, Joshi S, Lopez C, Goh G, Choi M, et al. Increased Levels of Macrophage Inflammatory Proteins Result in Resistance to R5-Tropic HIV-1 in a Subset of Elite Controllers. J Virol. 2015;89:5502-14 pubmed publisher
Sonnenberg G, Monticelli L, Alenghat T, Fung T, Hutnick N, Kunisawa J, et al. Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria. Science. 2012;336:1321-5 pubmed publisher
Hayakawa Y, Huntington N, Nutt S, Smyth M. Functional subsets of mouse natural killer cells. Immunol Rev. 2006;214:47-55 pubmed

product information

Product Type :

Antibody

Product Name :

CD56 (NCAM) Monoclonal Antibody (TULY56), APC, eBioscience

Catalog # :

17-0566-41

Quantity :

25 Tests

Price :

US 148.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human, Non-human primate, Rhesus Monkey

Applications :

Flow Cytometry: 5 uL (0.125 ug)/test

Species :

Human, Non-human primate, Rhesus Monkey

Clone :

TULY56

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of the immunoglobulin family that serves as an adhesive molecule and is ubiquitously expressed in the nervous system in isoforms ranging from 120-180 kDa. CD56 is found on T cells and NK cells, and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. Polysialic modification results in reduction of CD56-mediated cell adhesion. Through its extracellular region, CD56 mediates homophilic and heterophilic interactions by binding extracellular matrix components such as laminin and integrins. CD56 is expressed on most neuroectodermal derived cell lines, tissues and neoplasms such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma. Further, CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumors and ovarian granulosa cell tumors. Diseases associated with CD56 dysfunction include rabies and blastic plasmacytoid dendritic cell neoplasms.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (0.125 ug)/test

Aliases :

adhesion molecule; antigen recognized by monoclonal antibody 5.1H11; Cd56; CD-56; CD56 120 kDa GPI-linked isoform; CD56 140 kDa isoform; CD56 140 kDa VASE isoform; E NCAM; E-NCAM; MSK39; N CAM1; NCAM; N-CAM; Ncam1; N-CAM-1; NCAM-1; NCAMC; NCAM-C; neural cell adhesion molecule; Neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; sCD56; sNCAM; soluble CD56; soluble NCAM