CD49c (Integrin alpha 3) Monoclonal Antibody (P1B5), APC, eBioscience™ | Invitrogen 17-0494-42 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD49c (Integrin alpha 3) Monoclonal Antibody (P1B5), APC, eBioscience™

catalog :

17-0494-42

quantity :

100 Tests

price :

US 309.00

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

P1B5

reactivity :

human

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; 1:50; fig 2a, s2a	Menon V, Thomas R, Elgueta C, Horl M, Osborn T, Hallett P, et al. Comprehensive Cell Surface Antigen Analysis Identifies Transferrin Receptor Protein-1 (CD71) as a Negative Selection Marker for Human Neuronal Cells. Stem Cells. 2019;37:1293-1306 pubmed publisher
	Mitchell K, Szekeres C, Milano V, Svenson K, Nilsen Hamilton M, Kreidberg J, et al. Alpha3beta1 integrin in epidermis promotes wound angiogenesis and keratinocyte-to-endothelial-cell crosstalk through the induction of MRP3. J Cell Sci. 2009;122:1778-87 pubmed publisher
	Liddington R, Ginsberg M. Integrin activation takes shape. J Cell Biol. 2002;158:833-9 pubmed
	Wayner E, Gil S, Murphy G, Wilke M, Carter W. Epiligrin, a component of epithelial basement membranes, is an adhesive ligand for alpha 3 beta 1 positive T lymphocytes. J Cell Biol. 1993;121:1141-52 pubmed
	Wayner E, Carter W. Identification of multiple cell adhesion receptors for collagen and fibronectin in human fibrosarcoma cells possessing unique alpha and common beta subunits. J Cell Biol. 1987;105:1873-84 pubmed

product information

Product Type :

Antibody

Product Name :

CD49c (Integrin alpha 3) Monoclonal Antibody (P1B5), APC, eBioscience™

Catalog # :

17-0494-42

Quantity :

100 Tests

Price :

US 309.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 µL (0.125 µg)/test

Species :

Human

Clone :

P1B5

Isotype :

IgG1

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

ITGA3 (INTEGRIN, ALPHA-3), also called CD49C, VLA3 or GAPB3, is a protein that in humans is encoded by the ITGA3 gene. ITGA3 is an integrin alpha subunit which is also a member of the family of cell surface adhesion molecules. ITGA3 is mapped to chromosome 17 and its exact cytogenetic location is 17q21.33. ITGA3 makes up half of the alpha3beta1 integrin duplex that plays a role in neural migration and corticogenesis together with beta-1 subunit. A functional link between DAB1 phosphorylation and ITGA3 signaling drives the timely detachment of migrating neurons from radial glial fibers. Expression of human ITGA3 increased the infectivity of virus for Chinese hamster ovary cells. ITGA3 also contains 13 potential N-glycosylation sites, 2 potential cleavage sites, and the 7 N-terminal repeating units characteristic of ITGAs. Recombinant ITGA3 is expressed as a 150-kD protein as the same size as the native protein by the western blot analysis.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 µL (0.125 µg)/test

Aliases :

AA407068; alpha 3 subunit of VLA-3 receptor; Alpha3 integrin; antigen CD49C; antigen identified by monoclonal antibody J143; CD49 antigen-like family member C; CD49c; CD49c antigen; FLJ34631; FLJ34704; FRP-2; Galactoprotein B3; GAPB3; GAP-B3; ILNEB; integrin alpha 3; Integrin alpha3; Integrin alpha-3; Integrin alpha-3 heavy chain; Integrin alpha-3 light chain; integrin subunit alpha 3; integrin, alpha 3; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor); ITGA3; MSK18; testicular tissue protein Li 96; testicular tissue protein Li 98; VCA-2; very late activation protein 3 receptor, alpha-3 subunit; VL3A; VLA-3 subunit alpha; VLA3a

more info or order :

Invitrogen product webpage