CD43 Monoclonal Antibody (eBio84-3C1 (84-3C1)), APC, eBioscience | Invitrogen 17-0439-42 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD43 Monoclonal Antibody (eBio84-3C1 (84-3C1)), APC, eBioscience

catalog :

17-0439-42

quantity :

100 Tests

price :

US 317.00

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

eBio84-3C1 (84-3C1)

reactivity :

human

application :

flow cytometry

citations: 10

Reference
García Alegría E, Potts B, Menegatti S, Kouskoff V. In vitro differentiation of human embryonic stem cells to hemogenic endothelium and blood progenitors via embryoid body formation. STAR Protoc. 2021;2:100367 pubmed publisher
Ichisima J, Suzuki N, Samata B, Awaya T, Takahashi J, Hagiwara M, et al. Verification and rectification of cell type-specific splicing of a Seckel syndrome-associated ATR mutation using iPS cell model. J Hum Genet. 2019;64:445-458 pubmed publisher
Yoon J, Lee Y, Yu S, Yoon H, Park H, Joung C, et al. Aberrant expression of interleukin-10 and activation-induced cytidine deaminase in B cells from patients with Behçet's disease. Biomed Rep. 2017;7:520-526 pubmed publisher
Watanabe D, Koyanagi Aoi M, Taniguchi Ikeda M, Yoshida Y, Azuma T, Aoi T. The Generation of Human ??T Cell-Derived Induced Pluripotent Stem Cells from Whole Peripheral Blood Mononuclear Cell Culture. Stem Cells Transl Med. 2017;: pubmed publisher
Yang C, Ma R, Axton R, Jackson M, Taylor A, Fidanza A, et al. Activation of KLF1 Enhances the Differentiation and Maturation of Red Blood Cells from Human Pluripotent Stem Cells. Stem Cells. 2017;35:886-897 pubmed publisher
Jackson M, Ma R, Taylor A, Axton R, Easterbrook J, Kydonaki M, et al. Enforced Expression of HOXB4 in Human Embryonic Stem Cells Enhances the Production of Hematopoietic Progenitors but Has No Effect on the Maturation of Red Blood Cells. Stem Cells Transl Med. 2016;5:981-90 pubmed publisher
VÃ¡squez C, Franco M, Angel J. Rapid Proliferation and Differentiation of a Subset of Circulating IgM Memory B Cells to a CpG/Cytokine Stimulus In Vitro. PLoS ONE. 2015;10:e0139718 pubmed publisher
Cho J, Seo J, Lim C, Yang L, Shiratsuchi T, Lee M, et al. Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis. Cell Death Differ. 2015;22:1437-50 pubmed publisher
Sandler V, Lis R, Liu Y, Kedem A, James D, Elemento O, et al. Reprogramming human endothelial cells to haematopoietic cells requires vascular induction. Nature. 2014;511:312-8 pubmed publisher
Zawada A, Rogacev K, Hummel B, Grün O, Friedrich A, Rotter B, et al. SuperTAG methylation-specific digital karyotyping reveals uremia-induced epigenetic dysregulation of atherosclerosis-related genes. Circ Cardiovasc Genet. 2012;5:611-20 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD43 Monoclonal Antibody (eBio84-3C1 (84-3C1)), APC, eBioscience

Catalog # :

17-0439-42

Quantity :

100 Tests

Price :

US 317.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (0.25 ug)/test

Species :

Human

Clone :

eBio84-3C1 (84-3C1)

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

CD43 (leukosialin, sialophorin) is a transmembrane mucin-like protein with high negative charge, expressed on the surface of most hematopoietic cells. CD43 contributes to a repulsive barrier that interferes with cellular adhesion, however, in certain cases also promotes leukocyte aggregation. By interaction with actin-binding proteins ezrin and moesin CD43 plays a regulatory role in remodeling T-cell morphology and regulates cell-cell interactions during lymphocyte traffic. CD43 signaling both enhances LFA-1 adhesiveness and counteracts LFA-1 induction via other receptors. Expression of CD43 causes induction of functionally active tumor suppressor p53 protein, but in case of p53 and ARF deficiency CD43 promotes tumor proliferation and viability. CD43 appears to be an important modulator of leukocyte functions. Diseases associated with CD43 dysfunction include Wiscott-Aldrich Syndrome and Adenoid Basal Cell Carcinoma.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (0.25 ug)/test

Aliases :

3E8 antigen; A630014B01Rik; B-cell differentiation antigen LP-3; CD43; CD43 cytoplasmic tail; CD43-ct; Galactoglycoprotein; GALGP; gpL115; Leukocyte sialoglycoprotein; leukosialin; leukosianin; LOC101120462; LOW QUALITY PROTEIN: leukosialin; Lsn; Lsn1; Ly48; Ly-48; Lymphocyte antigen 48; sialophorin; sialophorin (gpL115, leukosialin, CD43); sialophorin gpL115; SPN; W3/13 antigen