This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD35 Monoclonal Antibody (E11), APC, eBioscience
catalog :
17-0359-42
quantity :
100 Tests
price :
US 363.00
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
E11

The same clone is also sold as:
reactivity :
human
application :
flow cytometry
citations: 5
Reference
Pawlowski A, Lannerg xe5 rd J, González Miro M, Cao D, Larsson S, Persson J, et al. A group B Streptococcus alpha-like protein subunit vaccine induces functionally active antibodies in humans targeting homotypic and heterotypic strains. Cell Rep Med. 2022;3:100511 pubmed publisher
Glodek A, Mirchev R, Golan D, Khoory J, Burns J, Shevkoplyas S, et al. Ligation of complement receptor 1 increases erythrocyte membrane deformability. Blood. 2010;116:6063-71 pubmed publisher
Tham W, Wilson D, Lopaticki S, Schmidt C, Tetteh Quarcoo P, Barlow P, et al. Complement receptor 1 is the host erythrocyte receptor for Plasmodium falciparum PfRh4 invasion ligand. Proc Natl Acad Sci U S A. 2010;107:17327-32 pubmed publisher
Khera R, Das N. Complement Receptor 1: disease associations and therapeutic implications. Mol Immunol. 2009;46:761-72 pubmed publisher
Hogg N, Ross G, Jones D, Slusarenko M, Walport M, Lachmann P. Identification of an anti-monocyte monoclonal antibody that is specific for membrane complement receptor type one (CR1). Eur J Immunol. 1984;14:236-43 pubmed
product information
Product Type :
Antibody
Product Name :
CD35 Monoclonal Antibody (E11), APC, eBioscience
Catalog # :
17-0359-42
Quantity :
100 Tests
Price :
US 363.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human, Non-human primate
Applications :
Flow Cytometry: 5 uL (0.06 ug)/test
Species :
Human, Non-human primate
Clone :
E11
Isotype :
IgG1, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
CD35 (CR1, Complement Receptor 1) is a cell membrane-bound, monomeric glycoprotein and its primary function is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. CD35 protein mediates cellular binding to particles and immune complexes that have activated complement. The CD35 complex is four different allotypes (C,A,B,D) C is 160 kDa; A is 190 kDa; B is 220 kDa and D is 250 kDa. CD35 is involved in the processing of immune complexes, promoting of binding and phagocytosis of C3b complexes and inhibition of complement activation. CD35 is on neutrophils, eosinophils, monocytes, B-cells, some NK-cells, erythrocytes, myeloid leukemias, follicular dendritic reticulum cells and is negative on basophils. Decreases in expression of CD35 protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in the CD35 gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants encoding different isoforms of CD35 have been characterized. An additional secreted form of CD35 have also been described but has not been fully characterized.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 5 uL (0.06 ug)/test
Aliases :
C3 binding protein; C3b/C4b receptor; C3-binding protein; C3BR; C4BR; CD35; CD35 antigen; complement component (3b/4b) receptor 1 (Knops blood group); Complement Component (3b/4b) receptor 1 including Knops blood group system; complement component 3b/4b receptor 1 (Knops blood group); complement receptor type 1; CR1; KN; Knops blood group antigen
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA