product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD16/CD32 Monoclonal Antibody (93), APC, eBioscience™
catalog :
17-0161-81
quantity :
50 µg
price :
US 309.00
clonality :
monoclonal
host :
rat
conjugate :
APC
clone name :
93
reactivity :
mouse
application :
flow cytometry
more info or order :
Invitrogen product webpage
citations: 20
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 3a
Lüscher Firzlaff J, Chatain N, Kuo C, Braunschweig T, Bochynska A, Ullius A, et al. Hematopoietic stem and progenitor cell proliferation and differentiation requires the trithorax protein Ash2l. Sci Rep. 2019;9:8262 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1a
Halvarsson C, Rörby E, Eliasson P, Lang S, Soneji S, Jönsson J. Putative role of NF-kB but not HIF-1α in hypoxia-dependent regulation of oxidative stress in hematopoietic stem and progenitor cells. Antioxid Redox Signal. 2019;: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1f
Salomè M, Magee A, Yalla K, Chaudhury S, Sarrou E, Carmody R, et al. A Trib2-p38 axis controls myeloid leukaemia cell cycle and stress response signalling. Cell Death Dis. 2018;9:443 pubmed publisher
  • flow cytometry; mouse; fig 1, 2, 3
Böiers C, Buza Vidas N, Jensen C, Pronk C, Kharazi S, Wittmann L, et al. Expression and role of FLT3 in regulation of the earliest stage of normal granulocyte-monocyte progenitor development. Blood. 2010;115:5061-8 pubmed publisher
Lam J, van den Bosch M, Wegrzyn J, Parker J, Ibrahim R, Slowski K, et al. miR-143/145 differentially regulate hematopoietic stem and progenitor activity through suppression of canonical TGFβ signaling. Nat Commun. 2018;9:2418 pubmed publisher
Qin Y, Wu L, Ouyang Y, Zhou P, Zhou H, Wang Y, et al. MiR-125a Is a critical modulator for neutrophil development. PLoS Genet. 2017;13:e1007027 pubmed publisher
Hérault A, Binnewies M, Leong S, Calero Nieto F, Zhang S, Kang Y, et al. Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis. Nature. 2017;544:53-58 pubmed publisher
Liu Z, Ravindranathan R, Kalinski P, Guo Z, Bartlett D. Rational combination of oncolytic vaccinia virus and PD-L1 blockade works synergistically to enhance therapeutic efficacy. Nat Commun. 2017;8:14754 pubmed publisher
Fang J, Bolanos L, Choi K, Liu X, Christie S, Akunuru S, et al. Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia. Nat Immunol. 2017;18:236-245 pubmed publisher
Patel M, Kim J, Theodros D, Tam A, Velarde E, Kochel C, et al. Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma. J Immunother Cancer. 2016;4:28 pubmed publisher
Schlam D, Canton J, Carreño M, Kopinski H, Freeman S, Grinstein S, et al. Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3,4,5-Trisphosphate Homeostasis. MBio. 2016;7:e02242 pubmed publisher
Yue Y, Li P, Song N, Li B, Li Z, Guo Y, et al. Genomic and immunologic factors associated with viral pathogenesis in a lethal EV71 infected neonatal mouse model. Mol Med Rep. 2016;13:4183-90 pubmed publisher
Li Y, Zhao L, Shi B, Ma S, Xu Z, Ge Y, et al. Functions of miR-146a and miR-222 in Tumor-associated Macrophages in Breast Cancer. Sci Rep. 2015;5:18648 pubmed publisher
Pirnes Karhu S, Mäntymaa P, Sironen R, Mäkinen P, Wojciechowski S, Juutinen S, et al. Enhanced polyamine catabolism disturbs hematopoietic lineage commitment and leads to a myeloproliferative disease in mice overexpressing spermidine/spermine N¹-acetyltransferase. Amino Acids. 2014;46:689-700 pubmed publisher
Pello O, Chevre R, Laoui D, De Juan A, Lolo F, Andrés Manzano M, et al. In vivo inhibition of c-MYC in myeloid cells impairs tumor-associated macrophage maturation and pro-tumoral activities. PLoS ONE. 2012;7:e45399 pubmed publisher
Capitano M, Nemeth M, Mace T, Salisbury Ruf C, Segal B, McCarthy P, et al. Elevating body temperature enhances hematopoiesis and neutrophil recovery after total body irradiation in an IL-1-, IL-17-, and G-CSF-dependent manner. Blood. 2012;120:2600-9 pubmed
Ninkovic J, Roy S. Morphine decreases bacterial phagocytosis by inhibiting actin polymerization through cAMP-, Rac-1-, and p38 MAPK-dependent mechanisms. Am J Pathol. 2012;180:1068-79 pubmed publisher
Varney M, Buchanan J, Dementieva Y, Hardman W, Sollars V. A high omega-3 fatty acid diet has different effects on early and late stage myeloid progenitors. Lipids. 2011;46:47-57 pubmed publisher
Marchlik E, Thakker P, Carlson T, Jiang Z, Ryan M, Marusic S, et al. Mice lacking Tbk1 activity exhibit immune cell infiltrates in multiple tissues and increased susceptibility to LPS-induced lethality. J Leukoc Biol. 2010;88:1171-80 pubmed publisher
Parker M, Xue S, Alexander J, Wasserfall C, Campbell Thompson M, Battaglia M, et al. Immune depletion with cellular mobilization imparts immunoregulation and reverses autoimmune diabetes in nonobese diabetic mice. Diabetes. 2009;58:2277-84 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CD16/CD32 Monoclonal Antibody (93), APC, eBioscience™
Catalog # :
17-0161-81
Quantity :
50 µg
Price :
US 309.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.25 µg/test
Species :
Mouse
Clone :
93
Isotype :
IgG2a, lambda
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
CD16 is a 50-65 kDa cell surface molecule that exists in two forms - a transmembranous form expressed by natural killer (NK) cells, and some T cells and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC (antibody dependent cell mediated cytotoxicity) by NK cells. IN comparison, CD32 is a 40 kD glycoprotein that acts as a low affinity receptor for IgG (also known as Fc gamma RII), and mediates several functions including endocytosis, activation of secretion, cytotoxicity and immunomodulation. CD32 is expressed by B cells, monocytes, granulocytes and platelets. Further, CD32 is involved in the phagocytosis of immune complexes, the regulation of antibody production by B-cells, and variations of the CD32 gene may increase vulnerability to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms of CD32 have been found.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.25 µg/test
Aliases :
AI528646; CD16; CD16a; CD16a antigen; CD16B; CD32; CD32 receptor 2; CD32B; CDw32; F630109E10Rik; Fc fragment of IgG low affinity IIIa receptor; Fc fragment of IgG receptor IIb; Fc fragment of IgG receptor IIIa; Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity III, receptor for (CD16); Fc fragment of IgG, low affinity IIIa, receptor (CD16a); fc gamma receptor IIB; Fc gamma receptor III; Fc gamma receptor IIIa; Fc gamma receptor III-A; Fc gamma receptor RII; Fc gamma RIIB; Fc gamma RIIIa; Fc receptor, IgG, low affinity IIb; Fc receptor, IgG, low affinity III; Fc[g]RII; Fcg receptor III; FCG2; FCG3; Fc-gamma receptor III-2 (CD 16); Fc-gamma receptor IIIb (CD16); fc-gamma RII; Fc-gamma RII-b; Fc-gamma RII-c; Fc-gamma RIII; Fc-gamma RIIIa; Fc-gamma RIII-alpha; Fc-gamma-RII; FcgammaRIIB; fc-gamma-RIIB; Fc-gamma-RIIc; FcgammaRIII; FcgammaRIIIA; Fcgr2; Fcgr2a; Fcgr2b; FCGR2C; Fcgr3; FCGR3A; FCGR3B; FcgRII; FCGRIII; FCR-10; Fcr-2; Fcr-3; fcRII; FcRII-b; FcRII-c; FCRIII; FCRIIIA; FGFR2B; IGFR3; IgG Fc receptor II beta; IgG Fc receptor III; IgG Fc receptor III-2; IMD20; immunoglobulin G Fc receptor III; low affinity immunoglobulin gamma Fc region receptor II; low affinity immunoglobulin gamma Fc region receptor II-b; low affinity immunoglobulin gamma Fc region receptor III; Low affinity immunoglobulin gamma Fc region receptor III-A; Ly-17; Lym-1; Ly-m20; lymphocyte antigen 17; neutrophil-specific antigen NA; RP11-5K23.1
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA