This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD15 Monoclonal Antibody (MMA), APC, eBioscience
catalog :
17-0158-42
quantity :
100 Tests
price :
US 363.00
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
MMA

The same clone is also sold as:
reactivity :
human
application :
flow cytometry
citations: 10
Reference
Zhao T, Liu S, Hanna N, Jalal S, Ding X, Wan J, et al. LAL deficiency induced myeloid-derived suppressor cells as targets and biomarkers for lung cancer. J Immunother Cancer. 2023;11: pubmed publisher
Jiang Z, Peng Z, Liu X, Guo H, Zhou M, Jiang D, et al. Neutrophil extracellular traps induce tumor metastasis through dual effects on cancer and endothelial cells. Oncoimmunology. 2022;11:2052418 pubmed publisher
Ummarino S, Hausman C, Gaggi G, Rinaldi L, Bassal M, Zhang Y, et al. NAD Modulates DNA Methylation and Cell Differentiation. Cells. 2021;10: pubmed publisher
Rahmani N, Ramachandra N, Sahu S, Gitego N, Lopez A, Pradhan K, et al. ASXL1 mutations are associated with distinct epigenomic alterations that lead to sensitivity to venetoclax and azacytidine. Blood Cancer J. 2021;11:157 pubmed publisher
Xia L, Jiang Y, Zhang X, Wang X, Wei R, Qin K, et al. SUMOylation disassembles the tetrameric pyruvate kinase M2 to block myeloid differentiation of leukemia cells. Cell Death Dis. 2021;12:101 pubmed publisher
Su R, Dong L, Li Y, Gao M, Han L, Wunderlich M, et al. Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion. Cancer Cell. 2020;38:79-96.e11 pubmed publisher
Markman J, Porritt R, Wakita D, Lane M, Martinon D, Noval Rivas M, et al. Loss of testosterone impairs anti-tumor neutrophil function. Nat Commun. 2020;11:1613 pubmed publisher
Huang Y, Su R, Sheng Y, Dong L, Dong Z, Xu H, et al. Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia. Cancer Cell. 2019;35:677-691.e10 pubmed publisher
Kasper M, Walscheid K, Laffer B, Bauer D, Busch M, Wildschütz L, et al. The Phenotype of Monocytes in Anterior Uveitis Depends on the HLA-B27 Status. Front Immunol. 2018;9:1773 pubmed publisher
Pellegrini W, Bresciani G, De Zorzi A, Marocolo D, Ungari M, Facchetti F. MMA monoclonal antibody is a superior anti-CD15 reagent for the diagnosis of classical Hodgkin's lymphoma?. Haematologica. 2007;92:708-9 pubmed
product information
Product Type :
Antibody
Product Name :
CD15 Monoclonal Antibody (MMA), APC, eBioscience
Catalog # :
17-0158-42
Quantity :
100 Tests
Price :
US 363.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 5 uL (0.125 ug)/test
Species :
Human
Clone :
MMA
Isotype :
IgM
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin's disease.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 5 uL (0.125 ug)/test
Aliases :
FUTIV; Lewis X; SSEA-1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA